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University of Cincinnati Patents
Assignee:
University of Cincinnati
Address:
Cincinnati, OH
No. of patents:
178
Patents:


1 2 3 4


Patent Number Title Of Patent Date Issued
7452720 Apparatus for preparing a biocompatible matrix November 18, 2008
An apparatus and method of using the apparatus to prepare a biocompatible biodegradable matrix capable of supporting cells to form an implantable or engraftable surgical device. A matrix-forming fluid is contained within a chamber defined by top and bottom surfaces of a thermally con
7450983 Automated brain MRI and CT prescriptions in Talairach space November 11, 2008
Brain Magnetic Resonance Imaging (MRI), Computerized Tomotography (CT), or other diagnostic modalities may employ a three-step procedure during initial ("scout") cranial pre-scans that corrects for patient positioning (i.e., roll, yaw and pitch) to reduce inter- and intra-patient variati
7449292 Methods for predicting relative efficacy of a beta blocker therapy based on a B1-adrenergic rece November 11, 2008
Methods and compositions for the detection, diagnosis, and prevention of cardiac conditions are provided. Polymorphisms of .beta..sub.1-adrenergic receptor are provided. The Gly389 .beta..sub.1-adrenergic receptor variants are not as responsive to treatment .beta. blockers such as ca
7430355 Light emissive signage devices based on lightwave coupling September 30, 2008
A signage device comprising one or more light sources, a waveguide or arrangement of waveguides and photoluminescent features coupled thereto. In one embodiment, a waveguide is adapted to receive light of a first wavelength and the photoluminescent features are adapted to emit light of
7378385 Role for GLP-1 to mediate responses to disparate stressors May 27, 2008
GLP-1 and GLP-1 receptor antagonists have been found to have a sedative or anxiolytic effect on the mammalian central nervous system. Conversely, GLP-1 and GLP-1 receptor agonists increase nervous system activity and the stress response. The invention relates, in one aspect, to the use o
7300414 Transcranial ultrasound thrombolysis system and method of treating a stroke November 27, 2007
A method of transcranial ultrasound thrombolysis comprises the steps of providing a predetermined level of ultrasonic energy substantially throughout a primary treatment zone encompassing the M1 branch and M2 branches of the middle cerebral artery of an individual. A thrombolytic age
7297312 Simultaneous multianalyte electrochemical assay based on spatial resolution November 20, 2007
A simultaneous multianalyte electrochemical assay includes a cell which has a surface and the surface includes analyte binding sites i.e., antibodies or antigens on a solid phase at distinct separate locations. Separate working electrodes are located within proximity to these separat
7241797 Method of increasing milk production July 10, 2007
The invention relates generally to the use of pharmaceutical compositions to increase milk production alone or in combination with certain biological active ingredients. Specifically, the method relates to the use of pharmaceutical compositions that will act on the feedback of the in
7229756 Alpha-2B-adrenergic receptor polymorphisms June 12, 2007
The present invention includes polymorphisms in nucleic acids encoding the alpha-2B adrenergic receptor and expressed alpha-2B adrenergic receptor molecule. The invention also pertains to methods and molecules for detecting such polymorphisms. The invention further pertains to the use
7211386 Alpha-2A-adrenergic receptor polymorphisms May 1, 2007
The present invention includes polymorphisms in nucleic acids encoding the alpha-2A adrenergic receptor and expressed alpha-2A adrenergic receptor molecule. The invention also pertains to methods and molecules for detecting such polymorphisms and transgenic animals expressing alpha-2A
7182807 Silane coatings for metal February 27, 2007
A method of treating a metal surface by application of a solution containing at least one vinyl silane and at least one bis-silyl aminosilane. A solution composition having at least one vinyl silane and at least one bis-silyl aminosilane is also provided, along with a silane coated m
7166627 Antibiotic compositions and methods of using the same January 23, 2007
The present invention relates to a process for the production of substituted 5-isoxazolidinone antibiotics. More specifically the patent relates to the production of compounds that mimic the antibiotic action of .beta.-lactams, are resistant to .beta.-lactamase degradation, and inhib
7135562 Avian iFABP gene expression controlling region November 14, 2006
A recombinant nucleic acid is provided having an avian promoter. One embodiment of the present invention contemplates the use of a gut-specific promoter, wherein a promoter can be the chicken intestinal fatty acid binding protein promoter region. A method for making a transgenic bird
7123796 Light emissive display based on lightwave coupling October 17, 2006
A light emissive display having a specular waveguide that propagates short wavelength light and photoluminescent features adjacent to the waveguide that fluoresce, for example, in visible red, green, blue, and mixed colors when selectively coupled with the short wavelength light. The
7118928 Method of forming a semiconductor phosphor layer by metalorganic chemical vapor deposition for u October 10, 2006
Light-emitting devices having a semiconductor phosphor layer formed by metalorganic chemical vapor deposition (MOCVD). The semiconductor phosphor layer may be any Group III nitride semiconductor compound that is in-situ doped during MOCVD deposition with one or more dopants effective
7096359 Authentication scheme for ad hoc and sensor wireless networks August 22, 2006
Strong authentication of packets sent between nodes of different clusters in a two-tier ad hoc network is provided by the cluster heads. Each cluster head authenticates nodes that enter the cluster. Thereafter, when a sending node requests a session from its cluster head with a receiving
7087281 Dielectric thin-film color optical memory device and fabrication process August 8, 2006
The DTF optical memory makes use of the property of dielectric thin film interference to create multi-color pixels and serve as a multi-level optical memory device. The fabrication of the device comprises a dielectric thin film deposited on a substrate that is micro-milled utilizing
7081084 Modular power system and method for a heart wall actuation system for the natural heart July 25, 2006
An actuation system for assisting the operation of a natural heart is disclosed. The actuation system includes a framework for interfacing with the natural heart and a power system that can be coupled to the framework. The framework includes an internal framework element and an exter
7041810 Alpha-2 adrenergic receptor polymorphisms May 9, 2006
The present invention includes polymorphisms in nucleic acids encoding the alpha-2B, alpha-2A, and alpha-2C adrenergic receptor and expressed alpha-2B, alpha-2A and alpha-2C adrenergic receptor molecule. The invention also pertains to methods and molecules for detecting such polymorp
7022296 Method for treating flue gas April 4, 2006
A multiple-field precipitator, flue-gas treating device, in accordance with the principles of the invention, includes a first section having a dual-function, sensible-cooling heat exchanger/electrostatic precipitator, a second section having a wet electrostatic precipitator, and a mi
6972516 Photopump-enhanced electroluminescent devices December 6, 2005
An electroluminescent device in which the intensity of the light emission is enhanced by photopumping with radiation from a radiation source of a suitable photon energy. The photopumping radiation from the radiation source interacts with the wide band-gap semiconductor forming the el
6962902 Compounds for control of appetite, blood pressure, cardiovascular response, libido, and circadia November 8, 2005
This invention relates generally to dipeptides and tripeptides and to methods for pharmaceutical treatment of mammals using analogs of such dipeptides and tripeptides. More specifically, the invention relates to tripeptides and their analogs, to pharmaceutical compositions containing
6955728 Acyloxy silane treatments for metals October 18, 2005
A method of treating a metal surface by application of a solution containing at least one acyloxy silane and at least one basic compound. A composition having at least one acyloxy silane and at least one basic compound is also provided, along with a silane coated metal surface.
6925391 Methods and apparatus for detecting artifactual output from a chemical analyzer August 2, 2005
A method and apparatus for examining data from a chemical analyzer for artifactual results. A set of rules are established to identify artifactual results based upon experience with the analyzer. Moreover, each rule can be associated with a sample collection or testing problem which
6925213 Micromachined fiber optic sensors August 2, 2005
A novel fiber optic sensor configuration whose diameter is the same as that of the optical fiber on which it is directly fabricated is introduced. A simple MEMS-compatible fabrication process to accomplish micromachining on the fiber end face has been developed and is detailed. This sens
6905105 Apparatus for preparing a biocompatible matrix June 14, 2005
An apparatus and method of using the apparatus to prepare a biocompatible biodegradable matrix capable of supporting cells to form an implantable or engraftable surgical device. A matrix-forming fluid is contained within a chamber defined by top and bottom surfaces of a thermally conduct
6861217 Variation in drug response related to polymorphisms in the .beta.2-adrenergic receptor March 1, 2005
A novel polymorphic site in the 5' leader cistron of the .beta..sub.2 -adrenergic receptor (.beta..sub.2 AR) gene is disclosed. The polymorphisms present at this site result in different levels of inhibition of translation of .beta..sub.2 AR mRNA. Compositions and methods for genotyp
6838240 Methods for diagnosis and treatment of Bloom's syndrome January 4, 2005
The present invention provides a method for diagnosing Bloom's syndrome (BS) as well as determining whether a subject is a carrier of a mutated BLM gene. The present invention also provides one or more single-stranded nucleic acid probes and antibodies which may be formulated in kits, an
6824986 Methods for measuring in vivo cytokine production November 30, 2004
The present invention involves techniques for evaluating in vivo cytokine production through the in vivo capture of secreting cytokines by labeled cytokine-binding reagents, followed by in vitro measurement of serum levels of captured cytokine. The methods of the present invention make u
6821799 Method of fabricating a multi-color light emissive display November 23, 2004
Multi-color light-emissive displays in which the constituent light-emissive devices providing the multiple colors are laterally integrated on the surface of a substrate. The light-emissive devices, typically emitting light by electroluminescence, are arranged such that adjacent devices e
6797478 Method of detecting axonal damage, from associated disease states using tau monoclonal antibodie September 28, 2004
Patients having several neurological diseases have been shown to have elevated levels of axonally-derived proteins (i.e. tau and neurofilament proteins) in cerebrospinal fluid (CSF) and in brain tissue. Three monoclonal antibodies (MAbs) recognizing CSF tau proteins were developed. T
6797472 Variation in drug response related to polymorphisms in .beta.2-adrenergic receptor September 28, 2004
A method for predicting an individual's response to the .beta.-agonists salmeterol, albuterol, metaproterenol, terbutaline and formoterol is disclosed. Individuals expressing the Ile164 .beta..sub.2 AR variant are likely to exhibit a reduced response as compared to individuals expressing
6737408 Compounds for control of appetite, blood pressure, cardiovascular response, libido, and circadia May 18, 2004
This invention relates generally to dipeptides and tripeptides and to methods for pharmaceutical treatment of mammals using analogs of such dipeptides and tripeptides. More specifically, the invention relates to tripeptides and their analogs, to pharmaceutical compositions containing
6737041 Non-ozone depleting vapocoolants May 18, 2004
Chemical compositions are provided, for use as topical anesthetics or skin refrigerants. These compositions do not cause the depletion of the stratospheric ozone layer and are non-toxic, non-carcinogenic and less flammable than ethyl chloride. Also these chemical compositions match the
6733510 Article and method for coupling muscle to a prosthetic device May 11, 2004
An insertion kit for positioning a plurality of filaments into muscle includes at least one holder that is configured for being attached to an end portion of the muscle. The holder is coupled with a guide, such as on a frame. The guide conforms the muscle to a desired shape. An inserter,
6635306 Light emissive display with a black or color dielectric layer October 21, 2003
Light emissive devices incorporating a low-reflectance black or color dielectric layer into their layered structure for improving the contrast of the emitted light. The black or color dielectric layer comprises a layer of a dielectric material having a network of passageways, such as
6592619 Heart wall actuation device for the natural heart July 15, 2003
An actuation system for assisting the operation of the natural heart comprises a framework for interfacing with a natural heart, through the wall of the heart, which includes an internal framework element configured to be positioned within the interior volume of a heart and an external
6589746 Method of detecting axonally-derived protein tau in patients with traumatic CNS injury July 8, 2003
Patients having several neurological diseases have been shown to have elevated levels of axonally-derived proteins (i.e. tau and neurofilament proteins) in cerebrospinal fluid (CSF) and in brain tissue. Three monoclonal antibodies (MAbs) recognizing CSF tau proteins were developed. T
6582375 System for study of global uni-or bi-ventricular function of an explanted, reperfused heart June 24, 2003
A system for studying a beating explanted heart comprises a fluid inflow circuit configured for coupling to an explanted heart to direct fluid for flowing into a ventricle of the heart, and a fluid outflow circuit configured for coupling to an explanted heart to direct fluid flowing out
6569811 Enhancement of JC in oxide superconductors May 27, 2003
The present invention comprises novel materials comprising composite high-Tc superconductors which contain a dispersion of precipitates and structural defects and thereby exhibit enhanced flux pinning and enhanced critical current in the superconducting state, and novel nanophase ori
6525808 Method and system for local index measurement in optical materials February 25, 2003
A method and system for determining a spatially local index of refraction in optical materials is provided. Light, including a near-field intensity, is collected above a surface of the material. A probe is oscillated at a plurality of frequencies and in a substantially perpendicular mann
6498009 .beta.-adrenergic receptor polymorphisms December 24, 2002
The invention concerns polymorphisms in the .beta..sub.1 - and the .beta..sub.2 -adrenergic receptors. The invention also pertains to methods and molecules for detecting such polymorphisms. The invention further pertains to the use of such molecules and methods in the diagnosis, prog
6488992 Product having a thin film polymer coating and method of making December 3, 2002
Elastomeric seals, including O-rings, may have chemically resistant thin films applied by the technique of plasma polymerization to the surface of the elastomer, enhancing wear resistance and environmental resistance without changing the physical properties of the elastomer. The films ma
6416869 Silane coatings for bonding rubber to metals July 9, 2002
A method of treating a metal substrate by applying a coating of a silane composition having at least one substantially unhydrolyzed aminosilane having one or more secondary or tertiary groups. Methods of adhering a polymer (such as rubber) to a metal substrate are also provided.
6409874 Rubber to metal bonding by silane coupling agents June 25, 2002
Adhesion of rubber to a variety of metals (aluminum, stainless steel, mild steel and brass) is effectively achieved by the application of an organofunctional silane (I) and a non-organofunctional silane (II) to the requisite surface. Preferably, the organofunctional silane (I) is a v
6409760 Device and method for restructuring heart chamber geometry June 25, 2002
A static device for use with the heart that has a plurality of members configured to be positioned adjacent the epicardial surface of the heart. The members are joined by at least one connector wherein the members are fixed in a spatial or spaced relationship relative to each other such
6406930 Fabrication of visible light emitting device formed from wide band gap semiconductor doped with June 18, 2002
A visible light emitting device includes a wide band gap semiconductor layer doped with one or more elements which emit light at various wavelengths based upon atomic transitions. The semiconductor preferably is GaN, InN, AIN, BN or alloys thereof doped with a lanthanide element such
6387956 Methods of treating obsessive-compulsive spectrum disorders May 14, 2002
A method of treating an obsessive-compulsive spectrum disorder comprises the step of administering an effective amount of tramadol to an individual.
6372296 High aluminum galvanized steel April 16, 2002
The present invention relates to galvanized steel having a high aluminum content in the coating, as well as a batch hot-dip galvanization process for making such steel. The galvanized steel herein has a coating comprising an inner layer of intermetallic iron aluminum compounds, such
6365698 Grafted polysilanes useful as photoinitiators and process for preparing same April 2, 2002
Grafted-polysilanes with a greater efficiency for the photoinitiation of vinyl type resins are provided. These grafted polysilanes which include both grafted cyclic polysilanes and grafted networked polysilanes have variable composition and length molecular chains grafted onto the silane
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