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Universite Pierre et Marie Curie Patents
Assignee:
Universite Pierre et Marie Curie
Address:
Paris, FR
No. of patents:
41
Patents:




Patent Number Title Of Patent Date Issued
7309605 Nucleotide sequence encoding the enzyme I-SceI and the uses thereof December 18, 2007
An isolated DNA encoding the enzyme I-SceI is provided. The DNA sequence can be incorporated in cloning and expression vectors, transformed cell lines and transgenic animals. The vectors are useful in gene mapping and site-directed insertion of genes.
7307726 Device for ellipsometric two-dimensional display of a sample, display method and ellipsometric m December 11, 2007
This invention concerns a device for ellipsometric two-dimensional display of a sample placed in an incident medium, observed between a convergent light cross-reflected analyser and polarizer, wherein the ellipsometric parameters of the ensemble formed by the sample and a substrate where
7271000 Nucleotide sequence encoding the enzyme I-Scel and the uses thereof September 18, 2007
An isolated DNA encoding the enzyme I-SceI is provided. The DNA sequence can be incorporated in cloning and expression vectors, transformed cell lines and transgenic animals. The vectors are useful in gene mapping and site-directed insertion of genes.
7254213 Radiological imagery method and device August 7, 2007
The relation relates to a method and a radiological imaging device. A subject (4) is illuminated by a luminous flux (1) generated by an X-ray source (2). This luminous flux (1) is a pulse having a duration t.sub.p shorter than 1 ms. The signals S derived from the interaction of the l
7217324 Method and device for producing an electronic GaAs detector for x-ray detection for imaging May 15, 2007
The invention relates to a method for producing an X-ray detector for imaging. By increasing the epitaxial layers, a GaAs material (1) is placed on a substrate n<+> (or p<+>) (2). p<+> (or n<+>)< >ions are then implanted on the external face (11) of the
7211564 Methods and construction and screening of libraries of chemokine variants May 1, 2007
The present invention provides a method for the design and/or the selection of agonist or antagonist chemokine variants combining a phage display technology and a screening on living cells expressing the receptor of the corresponding native chemokine. It also provides RANTES variants
7209232 Device for ellipsometric two-dimensional display of a sample, display method and ellipsometric m April 24, 2007
A device for ellipsometric two-dimensional display of a sample placed in an incident medium, observed between an analyser and a polarizer intersected by convergent light reflection, wherein the ellipsometric parameters of the assembly formed by the sample and a substrate whereon it i
7074411 .alpha.-.beta. C4BP-type recombinant heteromultimeric proteins July 11, 2006
A recombinant heteromultimeric protein including at least (a) a polypeptide fusion molecule A consisting of a C4BP .alpha.-chain C-terminal fragment and a polypeptide fragment heterologous to said .alpha.-chain, and (a) a polypeptide fusion molecule B consisting of a C4BP .beta.-chai
7011178 Sound transmitter and speaker March 14, 2006
A sound transmitter includes at least a vibrating membrane mounted on the wall of an enclosure so that one surface of the speaker membrane radiates in the enclosure, the enclosure being provided with a vent forming a conduit between an outlet inside the enclosure and an outlet outside th
6979554 Chemical structure having an affinity for a phospholipid and labeling compound diagnose kit and December 27, 2005
The present invention relates to a compound having affinity for a negatively charged phospholipid as well as to a detection molecule, to a conjugate and to a pharmaceutical composition comprising said compound.Generally speaking, the compound of the present invention is useful for specif
6926899 Glycoprotein peptide of the human herpesvirus-7 for use in particular in an elisa serologic test August 9, 2005
The invention concerns an immunogenic peptide comprising at least six consecutive amino acids of a hydrophilic region of the glycoprotein B (gB) of the human herpesvirus-7 (HIV-7), and reacting specifically with antibodies directed against HHV-7, and diagnosis kit containing it.
6875170 Positioning, exploration, and/or intervention device, in particular in the field of endoscopy an April 5, 2005
The positioning, intervention, and/or exploration device has two endpieces (6a-6d, 7) and at least one cable (20) extending from one endpiece to the other (6a-6d, 7), it has at least two bellows (10) each fixed directly to both of the endpieces and it has means (12, 18) for modifying the
6872528 Highly productive packaging lines March 29, 2005
The invention concerns a packaging eukaryotic cell for the production of defective infections viruses carrying a transgene, characterized in that it is deficient in one cell function essential to its growth, in particular in the presence of a selection culture medium, the function be
6870044 Inflammation inducible hybrid promoters, vectors comprising them and uses thereof March 22, 2005
The present invention relates to the field of the regulation of the expression of genes and is based in particular on the use of constructs which make it possible to activate the transcription of a transgene in cells, tissues or organs under inflammatory conditions. The promoters of
6841249 Method of a diamond surface and corresponding diamond surface January 11, 2005
The invention relates to a treatment method of a diamond surface and to a corresponding diamond surface (5A).According to the method, ions are produced, each having at least three positive charges, and a beam of these ions is sent towards a diamond surface in order to make at least one z
6833252 Nucleotide sequence encoding the enzyme I-SecI and the uses thereof December 21, 2004
An isolated DNA encoding the enzyme I-SceI is provided. The DNA sequence can be incorporated in cloning and expression vectors, transformed cell lines and transgenic animals. The vectors are useful in gene mapping and site-directed insertion of genes.
6822137 Nucleotide sequence encoding the enzyme I-SCEI and the uses thereof November 23, 2004
An isolated DNA encoding the enzyme I-SceI is provided. The DNA sequence can be incorporated in cloning and expression vectors, transformed cell lines and transgenic animals. The vectors are useful in gene mapping and site-directed insertion of genes.
6635248 Single-chain antibody fragments for transferring substances into cells October 21, 2003
The present invention provides novel polypeptides which can effectively penetrate into cells thereby transporting a substance of interest into the cells.
6624190 2-acylamino-2-deoxy-glucono-1,5-lactones, a method for the production thereof, compositions cont September 23, 2003
The invention concerns compounds of formula (I) wherein: A represents R.sub.1 or (O)R.sub.1 where R.sub.1 represents an alkyl group comprising 1 to 30 carbon atoms, linear or branched, saturated or unsaturated, capable of being partly or totally substituted by Hal where Hal represents
6608034 Immunovectors for the intracellular and intranuclear transport August 19, 2003
A product for coupling a biologically active principle with an immunovector, characterized in that the immunovector is capable of enabling the biologically active principle to be internalized into eukaryotic cells, and in that said immunovector has an affinity for the cell DNA to suc
6402882 Device and method for ion beam etching using space-time detection June 11, 2002
The invention concerns a device and a method for ion beam etching for producing an etched surface (2) on a semiconductor (1) or insulant The device comprises a positive ion source (20), means for guiding (23) an ion beam (42), a system for detecting the spatial and temporal interaction o
6383807 Method of transforming T lymphocytes May 7, 2002
The present invention discloses a method for transforming hematopoietic cells, in particular, T lymphocytes. The method involves co-culturing target cells, such as T lymphocytes, with pseudo-viral particles comprising a foreign DNA sequence.
6365405 Compositions of chondrocytes, preparation and utilization April 2, 2002
This invention concerns compositions of chondrocytic cells, notably human ones, and the methods for preparing and using them. More specifically, the invention describes the production of autologous human chondrocyte suspensions, employing recombinant enzymes and/or media that are com
6356565 Method of controlling bandwidth allocation in shared access local networks and a protocol and a March 12, 2002
To manage band allocation as a function of occupancy loading on a local network with high quality of service, the invention proposes a decentralized management protocol distributing allocation at all times by adapting the load of application streams to be transmitted to the bandwidth
6355574 Method and device for treating a semiconductor surface March 12, 2002
The invention concerns a method for treating a surface (2) of a semiconductor (1B) and a corresponding treating device. The surface is made by first molecules of the semiconductor having external bonds saturated with hydrogen. The method consists in sending a beam (30)of ions highly
6349279 Method for the voice recognition of a speaker using a predictive model, particularly for access February 19, 2002
The invention discloses a method for the voice recognition of a speaker using a q-order predictive model, comprising a step for extracting the statistical characteristics including a step of digital acquisition of the speaker's voice sample, corresponding to one or several utterances, a
6333171 CD4 gene regulatory sequences specifically expressed in mature T cells December 25, 2001
The present invention relates to compositions and methods for the expression of nucleic acids or polypeptides into mature T lymphocytes. The invention relates more specifically to methods of selective gene expression into mature T lymphocytes, based on CD4-derived regulatory sequence
6150181 Magnetic nanoparticles coupled to annexine, and utilization thereof November 21, 2000
The invention relates to a process for producing ferrofluid-forming magnetic particles substituted by DMSA (FFSH) that can be covalently coupled, directly or through a difunctional reactant, to an effector, which process comprises combining DMSA with ferrofluid-forming magnetic parti
6140114 Defective viral vaccine particles obtained in vivo or ex vivo October 31, 2000
The present invention relates to a vaccine consisting of defective viral particles as are obtained in vivo or ex vivo, in individuals infected or capable of being infected with a virus, after expression of the genes carried by a vector or a combination of vectors and comprising at least
6124098 Rapid detection of antibiotic resistance in mycobacterium tuberculosis September 26, 2000
A nucleotide sequence encoding a katG/lacZ fusion protein is useful for assaying the enzymatic activity of the katG gene product. A process of selecting a compound that is toxic against an isoniazid-resistant mycobaterial strain comprises incubating a catalase peroxidase enzyme with
6090378 Composition comprising interleukin-2 and thymidine kinase for the treatment of tumors July 18, 2000
Composition for use in the treatment of tumors and the immunization of humans or animals comprising a synergistic association of cells, viruses, or bacteria expressing, transitorily, in organisms at least one gene for producing in vivo one or more immunomodulators, and viruses, or cells
6080846 Composition containing a B epitope of the envelope glycoprotein of a retrovirus and a T epitope June 27, 2000
Compositions which comprise one or more B epitopes of the envelope glycoprotein of a retrovirus and one or more T epitope of the envelope glycoprotein from a distinct retrovirus, or a Tepitope from a different protein of the same retrovirus as the B epitope. In particular, the retrov
6004803 Genes encoding HSV1-TK containing a deletion of 5' cryptic promoter sites, vectors and cell line December 21, 1999
A recombinant vector comprising a gene encoding a Herpes Simplex Virus Type 1 thymidine kinase (HSV1-TK) comprising a deletion in the 5' sequence upstream of the second ATG initiation codon of the complete HSV1-TK sufficient to inhibit transcription initiation from a cryptic promoter
5948675 Host-vector system which can be used in gene therapy September 7, 1999
The invention relates to a system for expressing a transgene in a target cell or a human or animal cell, characterized in that it consists of a eukaryotic cell established as a line, into which there have been transfected:a) a recombinant viral sequence in which a gene has been deleted t
5906939 Cultured fibroblast or epithelial cell dissociation method using sulfated polysaccharide and che May 25, 1999
A cultured eukaryotic cell dissociation method using at least one polysaccharide polymer derivative. In particular, the method of dissociating cultured, adherent fibroblast or epithelial cells using a chelating agent such as EDTA and a sulfated polysaccharide such as heparin is discl
5866361 Nucleotide sequence encoding the enzyme I-SceI and the uses thereof February 2, 1999
An isolated DNA encoding the enzyme I-SceI is provided. The DNA sequence can be incorporated in cloning and expression vectors, transformed cell lines and transgenic animals. The vectors are useful in gene mapping and site-directed insertion of genes.
5843432 Retroviral vectors for the treatment of tumors, and cell lines containing them December 1, 1998
The invention relates to recombinant retroviral vectors, derived from Moloney MuLV, carrying a suicide gene susceptible of transforming an inactive substance into a toxic substance for cells going through a division process, said vectors being characterized by the presence in their s
5124442 Process for preparing AZT (3'-azido-3'-deoxy-thymidine) and related compounds June 23, 1992
The present invention relates to a process for preparing a compound of formula I ##STR1## from a compound of formula II ##STR2## via a compound of formula IV ##STR3## and to a compound of formula IV by way of an intermediate in the preparation of a compound of formula
5101023 Process for synthesising azido-3'-deoxythymidine and analogs March 31, 1992
The invention relates to a process for preparing a compound of formula (I) ##STR1## in which R.sub.1 is H, an alkyl radical or an alkoxy, hydroxyalkyl or halogen radical, and R.sub.3 is N.sub.3 or a CN radical, characterized in that a compound of formula (II): ##STR2## is rea
4992273 Antigens of Leishmania parasites February 12, 1991
The invention concerns hybridomes producing anti-Leishmania monoclonal antibodies which are characterized by their capacity to inhibit the infection of sarcomatous cells by the promastigote forms of one or more species of Leishmania, when the sarcomatous cells are placed in contact w
4765186 Liquid level detector by guided elastic waves August 23, 1988
The liquid level detector using guided waves, comprises a first transducer situated out of the liquid for sending an incident elastic pulse which propagates in an elongated guide of which the lower part is immersed in the liquid, a second transducer situated out of the liquid and receivi

 
 
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