| Patent Number |
Title Of Patent |
Date Issued |
| D336346 |
Collapisble bollard |
June 8, 1993 |
|
| D324920 |
Collapsible bollard |
March 24, 1992 |
|
| 7430323 |
Method and apparatus for 4-dimensional image warping |
September 30, 2008 |
| A method of atlas mapping and an apparatus for image mapping are provided. The method includes generating a four dimensional template, linearly transforming the four dimensional representation of a subject to the four dimensional template, generating attribute vectors for a plurality of |
| 7402308 |
Method of delivering genes to the central nervous system of a mammal |
July 22, 2008 |
| The invention provides a method of delivering a selected DNA sequence to the central nervous system of a mammal by administering to said mammal a neurotropic virus, said virus containing a selected DNA sequence under the control of a promoter which permits expression of the DNA during th |
| 7297820 |
Stilbene derivatives and their use for binding and imaging amyloid plaques |
November 20, 2007 |
| This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid pro |
| 7264762 |
Electrospinning ultrafine conductive polymeric fibers |
September 4, 2007 |
| A process of making conductive polymeric fibers by electrospinning fibers from a blend of polymers dissolved in an organic solvent includes generating a high voltage electric field between oppositely charged polymer fluid in a glass syringe (4) with a capillary tip (5) and a metallic |
| 7262290 |
Diagnostic markers for multiple epilepsy phenotypes |
August 28, 2007 |
| A mammalian KIR 4.1 gene and gene products which are predictive of a susceptibility or predisposition to neurological disorders such as multiple epilepsy phenotypes are provided. Methods of predicting an individual's susceptibility in developing or having a neurological disorder via |
| 7247614 |
Composition and method for modulating somatolactogenic function |
July 24, 2007 |
| A human prolactin-binding protein and compositions and methods using this protein are provided. |
| 7244704 |
Peptide scaffolds for transfer of molecules into eukaryotic cells |
July 17, 2007 |
| Compositions and methods of using compositions with a nuclear targeting peptide containing a nonclassical nuclear localization signal to deliver selected molecules to the nucleus of eukaryotic cells are provided. The compositions are particularly useful in gene transfer methods. |
| 7172760 |
Compositions and methods for prevention and treatment of uncontrolled formation of intravascular |
February 6, 2007 |
| Compositions and methods for prevention and treatment of uncontrolled formation of intravascular fibrin clots are provided wherein fibrinolytic or anticoagulant drugs are biocompatibly coupled to red blood cell carriers. |
| 7160994 |
Osteoclast-specific genes and proteins and uses thereof |
January 9, 2007 |
| Isolated nucleic acid and amino acid sequence for osteoclast-specific genes and proteins are provided. Methods for using these osteoclast-specific genes and proteins in the detection and isolation of osteoclasts, in production of antibodies specific to osteoclasts and to identify age |
| 7160676 |
Method of determining sperm capacitation |
January 9, 2007 |
| This invention describes unique patterns of distribution of ganglioside G.sub.M1 in non-capacitated sperm and demonstrates that the pattern of distribution of G.sub.M1 undergoes changes that can be correlated with the process of capacitation and/or with acrosomal exocytosis. Accordin |
| 7157087 |
Enhancement of intracellular delivery and tissue targeting of drugs and genes |
January 2, 2007 |
| A method for enhancing intracellular delivery of effector molecules is provided. The method involves modifying selected antibodies with biotin and streptavidin, conjugating these antibodies with an effector molecule, and delivering the conjugated effector to an intracellular target s |
| 7148269 |
Interfacial polymer incorporation of nanotubes |
December 12, 2006 |
| A method for producing a composite material containing nanotubes and an interfacial polymer, and a composite material made by the method. The method involves contacting two mutually insoluble monomer solutions, at least one of which contains nanotubes, to provide an insoluble polymer |
| 7122313 |
Methods and kits for identifying and quantifying RNAs and DNAs associated with RNA and DNA bindi |
October 17, 2006 |
| Methods and kits for identifying RNAs and DNAs associated with an RNA or DNA binding protein via a detector specific for the binding protein or protein bound thereto which is linked to an oligonucleotide capable of directing the synthesis of cDNA copies of RNA or DNA that are in close |
| 7119185 |
Hormonally up-regulated, neu-tumor-associated kinase |
October 10, 2006 |
| This invention relates generally to a novel serine/threonine protein kinase, specifically to hormonally up-regulated, neu-tumor-associated kinase (HUNK); and to the nucleotide sequence encoding it. The kinase is temporally expressed during postnatal mammary development in a spatially |
| 7115371 |
Rapid, sensitive and quantitative methods for tissue and cell-based proteomics via consecutive a |
October 3, 2006 |
| Methods, systems and kits are provided for detecting and quantifying multiple immunogens in a sample via consecutive addition of quantifiable extenders to immunogen bound complexes of immunogen binding agent attached to a DNA containing an RNA polymerase promoter. |
| 7105306 |
Methods and compositions for modulating somatolactogenic functions |
September 12, 2006 |
| Compositions containing cyclophilin B, mutants of cyclophilin B or inhibitors of cyclophilin B and methods of using these compositions to modulate somatolactogenic function are provided. |
| 7087436 |
Membrane countercurrent exchanger and membrane inlet mass spectrometer for the analysis of gas p |
August 8, 2006 |
| A method and apparatus for the analysis of blood or other liquids by mass spectrometry to determine the partial pressures of gases and other volatile substances dissolved in the blood or other liquid in a manner independent of the solubility of the gases in the blood or other liquid. |
| 7087060 |
Methods for obtaining hemostasis of percutaneous wounds |
August 8, 2006 |
| This invention relates to novel methods, kits, and devices for stopping hemorrhaging of percutaneous wounds. The inventive subject matter involves insertion of a purse-string suture around the wound, insertion of the free two ends of the suture through a tension collar, manual tighte |
| 7053121 |
Compositions and methods for regulating circadian rhythms |
May 30, 2006 |
| The present invention provides methods of effecting a change in the core circadian clock by modulating retinoid nuclear receptors. |
| 7052685 |
Methods for treatment of cutaneous T-cell lymphoma |
May 30, 2006 |
| A method and composition for treatment of advanced cutaneous T cell lymphoma is provided which involves administration of recombinant interleukin-12. |
| 7041287 |
Compositions and methods for selective dissolution of nascent intravascular blood clots |
May 9, 2006 |
| Compositions and methods for prevention and treatment of uncontrolled formation of intravascular fibrin clots, which are capable of selective dissolution of pathological nascent clots formed intravascularly, with minimal risk of unwanted dissolution of pre-existing hemostatic clots, |
| 7011827 |
Compositions and methods for producing and using homogenous neuronal cell transplants |
March 14, 2006 |
| Methods of treating individuals suspected of suffering from diseases, conditions or disorders of the Central Nervous System including nerve damage are provided wherein stable, homogeneous post-mitotic human neurons are into the individual's brain or at or near a site of nerve damage. |
| 6982743 |
Multispectral omnidirectional optical sensor and methods therefor |
January 3, 2006 |
| Provided is a multispectral and omnidirectional imaging sensor and system that produces improved surround awareness, as well as methods of use therefor. The multispectral omnidirectional optical sensor device comprises a series of view and reflecting mirrors for splitting the electro |
| 6982156 |
Compositions and methods modulating variola and vaccinia virus |
January 3, 2006 |
| Antibodies directed to SPICE and VCP which may be used for detection, prevention, and treatment of variola virus or vaccinia virus are provided. Recombinant SPICE and VCP proteins are also provided which are used for enhancing the immune response to variola or vaccinia virus and modu |
| 6979673 |
Method and compositions for modulating somatolactogenic functions |
December 27, 2005 |
| Compositions containing cyclophilin B, mutants of cyclophilin B or inhibitors of cyclophilin B and methods of using these compositions to modulate somatolactogenic function are provided. |
| 6979572 |
Compositions and methods for inhibiting inward-rectifier potassium channels |
December 27, 2005 |
| The present invention provides compounds and methods of identifying and designing compounds which inhibit activity of inward-rectifier K.sup.+ channels. In particular, compounds having a tertiapin-like .alpha. helix, such as a stable tertiapin derivative wherein the methionine residue in |
| 6975894 |
Digital topological analysis of trabecular bone MR images and prediction of osteoporosis fractur |
December 13, 2005 |
| The invention provides method, system and device for determining trabecular bone structure and strength by digital topological analysis, and offers, for the first time, a demonstration of superior associations between vertebral deformity and a number of architectural indices measured in |
| 6962688 |
Methods for modulation of cholesterol transport |
November 8, 2005 |
| Methods for regulation of lipid and cholesterol uptake are described which are based on regulation of the expression or function of the SR-BI HDL receptor. The examples demonstrate that estrogen dramatically downregulates SR-BI under conditions of tremendous upregulation of the LDL-r |
| 6961600 |
Transbronchial reflectance oximetric measurement of mixed venous oxygen saturation, and device t |
November 1, 2005 |
| Provided are methods and a system for the transbronchial reflectance oximetric measurement of mixed venous oxygen saturation in the pulmonary artery of a patient, and a device therefor. Thus, provided is a quick, minimally invasive, method and system for determining an important endp |
| 6958196 |
Porous electrode, solid oxide fuel cell, and method of producing the same |
October 25, 2005 |
| The present invention generally relates to porous electrodes for use in solid oxide fuel cells, whereby the electrodes are comprised primarily of ceramic material and electronically conductive material. The electrodes are prepared by impregnating a porous ceramic material with precursors |
| 6953676 |
Mesoscale polynucleotide amplification device and method |
October 11, 2005 |
| Disclosed are devices for amplifying a preselected polynucleotide in a sample by conducting a polynucleotide polymerization reaction. The devices comprise a substrate microfabricated to define a sample inlet port and a mesoscale flow system, which extends from the inlet port. The mesosca |
| 6927278 |
Peptide scaffolds for transfer of molecules into eukaryotic cells |
August 9, 2005 |
| Compositions and methods of using compositions with a nuclear targeting peptide containing a nonclassical nuclear localization signal to deliver selected molecules to the nucleus of eukaryotic cells are provided. The compositions are useful for gene transfer. |
| 6915151 |
Quantitative pulmonary imaging |
July 5, 2005 |
| The present invention comprises imaging and quantitative measurement of lung ventilation, particularly in a human lung. Methods for quantitative imaging of lung ventilation, and the further provided systems and algorithmic tools therefore, comprise three primary components: the combi |
| 6908742 |
Methods and kits for the detection of endotoxin |
June 21, 2005 |
| Methods for determining levels of endotoxin in a sample are provided. These methods are useful in the diagnosis of septicemia. Kits for the detection of endotoxin are also provided. |
| 6897009 |
Fabrication of nanometer size gaps on an electrode |
May 24, 2005 |
| A shadow mask method to fabricate electrodes with nanometer scale separation utilizes nanotubes (NTs). Metal wires with gaps are made by incorporating multi-wall carbon nanotubes (MWNTs) or single-wall carbon nanotubes (SWNTs) (or bundles thereof) into a tri-layer electron beam litho |
| 6885762 |
Scale-based image filtering of magnetic resonance data |
April 26, 2005 |
| The invention provides novel scale-based filtering methods that use local structure size or "object scale" information to arrest smoothing around fine structures and across even low-gradient boundaries. One method teaches a weighted average over a scale-dependent neighborhood; while |
| 6867187 |
Composition and method for modulating somatolactogenic function |
March 15, 2005 |
| A human prolactin-binding protein and compositions and methods using this protein are provided. |
| 6858011 |
Method and apparatus to control microbubble destruction during contrast-enhanced ultrasound imag |
February 22, 2005 |
| Methods and apparatus are provided for controlling fluid flow or perfusion, wherein gas-filled microbubbles are used as ultrasound contrast-enhancing agents, and wherein the method comprises separating the removal of the contrast agent due to flow from the removal of the contrast agent d |
| 6831153 |
Gene and methods for diagnosing neuropsychiatric disorders and treating such disorders |
December 14, 2004 |
| A mammalian 22444 gene and gene products which are predictive of a susceptibility or predisposition to various neuropsychiatric disorders are provided. Methods of predicting an individual's susceptibility to developing or having a neuropsychiatric disorder via detection of these diag |
| 6797816 |
Identification and cloning of a new subfamily of sulfatases and functional embryonic techniques |
September 28, 2004 |
| Nucleic acid sequences encoding members of a new subfamily of sulfatases and polypeptides encoded thereby are provided. Compositions and methods of modulating sulfatases of this new subfamily to modify growth properties and differentiation of cells, as well as the ability of cells to pre |
| 6783759 |
Compositions and methods for modulating variola virus |
August 31, 2004 |
| Antibodies directed to SPICE which may be used for detection, prevention, and treatment of variola virus are provided. Recombinant SPICE and VCP proteins are also provided which are used for enhancing the immune response to variola virus. Furthermore, modulation of complement activat |
| 6720553 |
Tip calibration standard and method for tip calibration |
April 13, 2004 |
| The present invention is directed to a tip calibration standard for characterizing the geometric and electrostatic properties of the probe tips of scanning probe microscopes comprising a carbon nanotube mounted on a dielectric surface of a grounded, conductive substrate and connected to |
| 6701168 |
Apparatus for measuring an oxygen concentration gradient and method of use thereof |
March 2, 2004 |
| The invention provides an improved, reliable and efficient way of measuring the oxygen concentration gradient in a sample by a novel apparatus and accompanying method of calculating linear oxygen concentrations within the sample, permitting diagnostic testing, for example, of the effects |
| 6698885 |
Judging changes in images of the eye |
March 2, 2004 |
| The invention includes a computer-implemented method, system (100), and computer-readable medium having computer-executable modules for judging changes in components of an eye. The inventive computer-implemented method includes the steps of acquiring (103), displaying (107), and superimp |
| 6696039 |
Amyloid plaque aggregation inhibitors and diagnostic imaging agents |
February 24, 2004 |
| This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid pro |
| 6673039 |
Compositions, kits, methods, and apparatus for transvascular delivery of a composition to an ext |
January 6, 2004 |
| Compositions, methods, kits, and apparatus are provided for delivering a macromolecular assembly such as a plasmid, virus vector, or other gene vector, to an extravascular tissue such as muscle tissue. The composition comprises the macromolecular assembly and a vascular permeability- |
| 6660517 |
Mesoscale polynucleotide amplification devices |
December 9, 2003 |
| Disclosed are devices for amplifying a preselected polynucleotide in a sample by conducting a polynucleotide amplification reaction. The devices are provided with a substrate microfabricated to include a polynucleotide amplification reaction chamber, having at least one cross-sectional |
| 6630067 |
Methods and apparatus for biological treatment of aqueous waste |
October 7, 2003 |
| A biofilter system of the present invention utilizes an Alternating-Aerobic-Anoxic (AAA) process in a single reactor to provide efficient and cheap removal of carbonaceous materials, nitrogenous materials, and/or mixtures thereof from aqueous waste. The biofilter system of the presen |
