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Transform Pharmaceuticals, Inc. Patents |
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Assignee: Transform Pharmaceuticals, Inc.
Address: Lexington, MA
No. of patents: 17
Patents:
| Patent Number |
Title Of Patent |
Date Issued |
| 7449342 |
Methods of manipulating small amounts of solids |
November 11, 2008 |
| The invention relates to methods and apparatuses for manipulating small amounts of solids. Specific embodiments of the invention are particularly suited for the automated transfer of small amounts of solids. In one embodiment, a uniform powder bed is lightly compressed into plugs of |
| 7449307 |
Raised surface assay plate |
November 11, 2008 |
| The assay plate includes a substrate having an substrate surface and at least one raised pad extending from the substrate surface. The raised pad includes a substantially planar sample receiving surface configured for holding a sample thereon for in situ experimentation. The sample r |
| 7446107 |
Crystalline forms of conazoles and methods of making and using the same |
November 4, 2008 |
| The invention provides novel soluble conazole crystalline forms (e.g. itraconazole, posaconazole and saperconazole) that include salts, co-crystals and related solvates useful as pharmaceuticals. The invention also provides pharmaceutical compositions comprising, and processes for ma |
| 7408632 |
Miscibility determination of a combination of liquids |
August 5, 2008 |
| The present invention provides methods for the determination of miscibility of a mixture of two or more liquids. Measurements of the local deviation of a pattern characteristic or of the variation in light intensity are employed in such determinations. |
| 7205413 |
Solvates and polymorphs of ritonavir and methods of making and using the same |
April 17, 2007 |
| Novel solvates and crystal polymorphs of Ritonavir are disclosed, as well as methods of making them. Specific solvates of the compound include a formamide solvate and a partially desolvated solvate. Also disclosed are methods of making previously known forms of Ritonavir. Methods of usin |
| 7186863 |
Sertraline compositions |
March 6, 2007 |
| An acid salt of sertraline, wherein the acid is citric acid, fumaric acid, malic acid, maleic acid, malonic acid, phosphoric acid, succinic acid, sulfuric acid, L-tartaric acid, HBr, acetic acid, benzoic acid, benzenesulfonic acid, ethanesulfonic acid, lactic acid, methanesulfonic ac |
| 7172859 |
System and method for optimizing tissue barrier transfer of compounds |
February 6, 2007 |
| The present invention relates to high-throughput systems and methods to prepare a large number of component combinations, at varying concentrations and identities, at the same time, and high-throughput methods to test tissue barrier transfer, such as transdermal transfer, of componen |
| 7108970 |
Rapid identification of conditions, compounds, or compositions that inhibit, prevent, induce, mo |
September 19, 2006 |
| The invention concerns arrays comprising hundreds, thousands, to hundreds of thousands of samples and methods for screening thereof. These methods are useful to optimize, select, and discover compounds, compositions, or conditions that prevent, inhibit, induce, modify, or reverse phy |
| 7078526 |
CIS-itraconazole crystalline forms and related processes, pharmaceutical compositions and method |
July 18, 2006 |
| The invention provides novel soluble conazole crystalline forms (e.g. itraconazole, posaconazole and saperconazole) that include salts, co-crystals and related solvates useful as pharmaceuticals. The invention also provides pharmaceutical compositions comprising, and processes for ma |
| 7061605 |
Apparatus and method for high-throughput preparation and spectroscopic classification and charac |
June 13, 2006 |
| Systems and methods are described that allow the high-throughput preparation, processing, and study of arrays of samples, each of which comprises at least one compound. Particular embodiments of the invention allow a large number of experiments to be performed in parallel on samples |
| 6977723 |
Apparatus and method for high-throughput preparation and spectroscopic classification and charac |
December 20, 2005 |
| Systems and methods are described that allow the high-throughput preparation, processing, and study of arrays of samples, each of which comprises at least one compound. Particular embodiments of the invention allow a large number of experiments to be performed in parallel on samples |
| 6919370 |
Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable |
July 19, 2005 |
| The invention concerns paclitaxel solubilizers and formulations thereof with a high propensity to dissolve paclitaxel. The formulations of the invention reduce or obviate the need for the disadvantageous excipient Cremophor.RTM. EL. The formulations of the invention are useful for ad |
| 6908760 |
Raised surface assay plate |
June 21, 2005 |
| The assay plate includes a substrate having an substrate surface and at least one raised pad extending from the substrate surface. The raised pad includes a substantially planar sample receiving surface configured for holding a sample thereon for in-situ experimentation. The sample recei |
| 6852526 |
Transdermal assay with magnetic clamp |
February 8, 2005 |
| The transdermal assay apparatus includes first, second, and third members. The first member has one or more sample surfaces, each of which is configured to receive a sample thereon. The second member defines one or more reservoirs, each of which has an opening on a surface of the second |
| 6758099 |
System and method for optimizing tissue barrier transfer of compounds |
July 6, 2004 |
| The present invention relates to high-throughput systems and methods to prepare a large number of component combinations, at varying concentrations and identities, at the same time, and high-throughput methods to test tissue barrier transfer, such as transdermal transfer, of componen |
| 6699840 |
Controlled- or delayed-release forms of topiramate |
March 2, 2004 |
| The invention encompasses novel salts of topiramate, and pharmaceutically acceptable polymorphs, solvates, hydrates, dehydrates, co-crystals, anhydrous, or amorphous forms thereof, as well as pharmaceutical compositions and pharmaceutical unit dosage forms containing the same. In par |
| 6559293 |
Topiramate sodium trihydrate |
May 6, 2003 |
| The invention encompasses novel salts of topiramate, and pharmaceutically acceptable polymorphs, solvates, hydrates, dehydrates, co-crystals, anhydrous, or amorphous forms thereof, as well as pharmaceutical compositions and pharmaceutical unit dosage forms containing the same. In par |
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