| Patent Number |
Title Of Patent |
Date Issued |
| RE35053 |
Amines useful in producing pharmaceutically active CNS compounds |
October 10, 1995 |
| Disclosed are .DELTA..sup.9(11) -steroids (VI) and amino substituted steroids (XI) which contain an amino group attached to the terminal carbon atom of the C.sub.17 -side chain, more particularly amino steroids (Ia and Ib), aromatic steroids (II), .DELTA..sup.16 -steroids (IIIa and IIIb) |
| RE33364 |
Non-aromatic oxygenated strong acid dehydration of 9.alpha.-hydroxyandrostenediones |
October 2, 1990 |
| The present invention discloses a process for the production of androsta-4,9(11)-diene-3,17-dione type compounds from 9.alpha.-hydroxyandrostenedione type compounds by non-aromatic oxygenated strong acid dehydration. |
| RE33102 |
Removal of volatile contaminants from the vadose zone of contaminated ground |
October 31, 1989 |
| Volatile contaminants are removed from the vadose zone of contaminated ground by pumping volatilized contaminants from the vadose zone using one or more vacuum extraction wells. |
| RE31703 |
Process of making particle board from pyrophosphate treated polyisocyanates |
October 9, 1984 |
| A process is disclosed for the preparation of liquid, storage-stable, polyisocyanate compositions containing a release agent formed in situ which compositions are useful, for example, as binder resins in the formation of particle boards which latter, because of the presence of the re |
| RE31671 |
Thermoplastic polyurethane elastomers from polyoxypropylene polyoxyethylene block copolymers |
September 11, 1984 |
| Polyurethane polyether-based elastomers are described which are thermoplastic, recyclable and have increased high temperature resistance which permits fabrication by injection molding. The elastomers are the product of reaction of 4,4'-methylenebis(phenyl isocyanate), a particular gr |
| RE31578 |
.alpha.(Substituted) amino-3-substituted-2-isoxazoline-5-acetic acids (esters) |
May 1, 1984 |
| Chemical process for preparing AT-125 and its analogs and intermediates used in the process. |
| RE30837 |
N-(2-Aminocycloheptyl)alkanoylanilides |
December 29, 1981 |
| N-(2-aminocycloheptyl)N-alkanoylanilides and their 2-N-oxides of the formula ##STR1## e.g., trans-3,4-dichloro-N-[2-(allylamino)cycloheptyl]propionanilide, and their pharmacologically acceptable salts, have been found to possess potent Central Nervous System antidepressant proper |
| RE30439 |
Treatment of genital tract diseases of domestic animals with prostaglandins |
November 25, 1980 |
| The treatment of purulent diseases of the female genital track of domestic animals by administration of an amount of a domestic animal luteolytic-uterine smooth muscle stimulating prostaglandin (DALUSMUS-PG) effective to cure said disease is disclosed. |
| RE30053 |
PG-type, 1,9-lactones |
July 24, 1979 |
| The present invention provides novel 1,9 lactones of prostaglandin-type free acids and a process for their preparation. These lactones are useful for the same pharmacological purposes as the corresponding prostaglandin-type free acids. |
| RE29926 |
2-Decarboxy-2-hydroxy-methyl-16-fluoro-PGE.sub.1 compounds |
March 6, 1979 |
| This invention comprises certain analogs of the prostaglandins in which the C-1 carboxyl is replaced by a primary alcohol. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit p |
| RE29558 |
Lincomycin analogs |
February 28, 1978 |
| Compounds of the formula: ##STR1## are disclosed, wherein R.sub.1 taken independently is hydrogen; R.sub.2 taken independently is the moiety ##STR2## wherein Ac is carboxacyl or an acyl group of formula: ##STR3## wherein Z is hydrogen, lower alkyl or a protective group re |
| PP5171 |
Tomato plant |
January 3, 1984 |
| A new and distinct variety of a hybrid tomato plant substantially as herein shown and described, characterized as to novelty when compared to Flora-Dade, Tempo and Walter, the most similar cultivars to it, by uniform crop characteristics, low grading loss, high yield, large fruit, low |
| PP4539 |
Tomato plant |
May 27, 1980 |
| A new and distinct variety of a hybrid tomato plant substantially as herein shown and described, characterized as to novelty when compared to Walter, the most similar variety to it, by uniform crop characteristics, low grading loss, high yield, early maturity, low percentage of fruit wit |
| D350601 |
Vaginal drug delivery insert |
September 13, 1994 |
|
| D310579 |
Triscored drug tablet |
September 11, 1990 |
|
| D309035 |
Drug tablet |
July 3, 1990 |
|
| D267653 |
Combined portfolio and writing pad |
January 18, 1983 |
|
| 6331636 |
Therapeutically useful 2-aminotetralin derivatives |
December 18, 2001 |
| This invention is therapeutically useful 2-aminotetralins and pharmaceutically acceptable acid addition salts thereof of the formula ##STR1##These compounds are useful to treat central nervous system disorders, hypertension, diabetes, sexual impotency and to control appetite. |
| 6008253 |
Use of 3-guanidinopropionic acid to increase endurance, stamina and exercise capacity in a mamma |
December 28, 1999 |
| The present invention provides a new food product and use for a known compound. More particularly, the present invention provides a new food product containing 3-guanidinopropionic acid and a method of using 3-guanidinopropionic acid to increase endurance, stamina and exercise capaci |
| 5721132 |
Synthetic gene for D4 dopamine receptors |
February 24, 1998 |
| A modified gene coding for the human D4 dopamine receptor has been synthesized by chemo-enzymatic methods. The nucleotide sequence of the D4 dopamine receptor gene was changed to reduce the G+C content and to eliminate intronic sequences, while maintaining the published amino acid se |
| 5663305 |
Somatotropin analogs |
September 2, 1997 |
| The present invention provides analogs of animal somatotropins particularly with changes in the amino acids between residue 96 to 133 which are changed to reduce hydrophobicity or helical stability. |
| 5650427 |
Centrally acting 6,7,8,9-tetrahydro-3H-benz(e) indole heterocyclics |
July 22, 1997 |
| A compound of Formula I ##STR1## or pharmaceutically acceptable salts of Formula I, where R.sup.1 is H, C.sub.1 -C.sub.3 alkyl, --(CH.sub.2).sub.n CONH.sub.2 where n is 2 to 6, (CH2).sub.n -1-(4,4-dimethylpiperidine-2,6-dione-yl), or cyclopropylmethyl;R.sup.2 is hydrogen, C.sub.1 |
| 5643942 |
Methods, composition and solutions for treating alopecia |
July 1, 1997 |
| This invention relates to the method for treating the form of alopecia commonly known as "male pattern baldness" which comprises regular topical application to the affected areas of the human scalp of a composition containing as at least one of its active ingredients of Formula I. It als |
| 5643940 |
Dioxapyrrolomycin as an antiparasitic agent and compositions useful therefor |
July 1, 1997 |
| This invention concerns a method for killing internal parasites, especially nematodes, trematodes and cestodes affecting warm blooded animals such as sheep, cattle, swine, goats, dogs, cats, horses and humans as well as poultry by administering an effective amount of dioxapyrrolomycin of |
| 5643895 |
Phosphonoacetic esters and acids as anti-inflammatories |
July 1, 1997 |
| Compounds useful in the treatment of inflammation structurally represented as Formula I ##STR1## one of X or Y is H and the other is selected from the group consisting of: ##STR2## or X and Y are taken together to form a ring selected from the group consisting of: ##STR3# |
| 5635495 |
Pyrimidine bisphosphonate esters and (alkoxymethylphosphinyl)alkyl phosphonic acids as anti-infl |
June 3, 1997 |
| Compounds useful in the treatment of inflammation structurally represented as ##STR1## wherein X,X.sup.1 and R groups are as herein defined. |
| 5633374 |
Pyrimidine, cyanoguanidines as K-channel blockers |
May 27, 1997 |
| Pyrimidine-cyanoguanidine compounds of Formula I and its pharmaceutically acceptable acid addition salts ##STR1## wherein R.sub.1 is hydrogen or methyl;R.sub.2 is C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 alkenyl, C.sub.2 -C.sub.6 alkynyl, C.sub.3 -C.sub.5 cycloalkyl, C.sub.3 -C.sub.5 |
| 5631227 |
Somatotropin analogs |
May 20, 1997 |
| The present invention provides analogs of somatotropins wherein the asparagine residue corresponding to position 99 of a bovine somatotropin is replaced with a compound selected from the group consisting of proline, aspartic acid, glutamic acid, serine, glycine, serine-serine or seri |
| 5622845 |
Fermentation method for producing norleucine |
April 22, 1997 |
| The present invention provides an inexpensive fermentation medium for growing microorganisms. Also provided are fermentation media and methods for producing norleucine by growing E. coli thereon, fermentation media and methods for incorporating norleucine into polypeptides expressed by |
| 5621123 |
Cyclic hydrocarbons with an aminoalkyl sidechain |
April 15, 1997 |
| Provided are cyclic hydrocarbons of Formula I ##STR1## with an aminoalkyl sidechain that are useful for treating phospholipase A2 mediated conditions, diabetes, and obesity. |
| 5616320 |
Use of antibiotics 10381b to promote growth |
April 1, 1997 |
| Antibiotic 10381a.sub.1, wherein R is hydrogen, is a cytosine-containing antibiotic producible by culturing the novel microorganism Streptomyces arginensis in an aqueous medium and isolation thereof. Derivatives wherein R is a C.sub.1 to C.sub.3 alkyl ester of antibiotic 10381a.sub.1, ar |
| 5610158 |
4-oxo- and 4H-imidazo(5,1-c)(1,4)benzoxazines useful as benzodiazepine receptor-binding agents |
March 11, 1997 |
| Imidazo-benzoxazines of Formula (I) and pharmaceutically acceptable salts thereof. ##STR1## where Q is selected from (A) through (H) ##STR2## or pharmaceutically acceptable salts thereof wherein the R groups are as defined herein. The imidazo-benzoxazines, Formula (I), of the |
| 5602115 |
Bisphosphonic acid derivatives as anti-arthritic agents |
February 11, 1997 |
| The bisphosphonates of formula (III)bicyclic bisphosphonates (V), and cyclic bisphosphonates (VII) are useful as antiarthritic agents and do not have the side effects of anti-arthritic agents which are prostaglandin synthetase inhibitors. |
| 5601974 |
Method of detecting viral infection in vaccinated animals |
February 11, 1997 |
| Provided are methods for determining whether a vaccinated animal is uninfected or infected with a virulent wild-type virus. Methods, vaccines and viruses are disclosed that are useful to seratologically distinguish infected from uninfected animals in populations of animals vaccinated wit |
| 5599930 |
Substituted indoles as anti-AIDS pharmaceuticals |
February 4, 1997 |
| Substituted indoles of formula (I) ##STR1## are useful anti-AIDS pharmaceuticals. |
| 5599841 |
Use of 3-guanidinopropionic acid in the treatment and prevention of metabolic disorders |
February 4, 1997 |
| The present invention provides a method for treating or preventing certain metabolic disorders comprising the systemic administration of 3-guanidinopropionic acid. |
| 5597816 |
Pyrazoloazepino substituted oximes useful as anti-atherosclerosis and anti-hypercholesterolemic |
January 28, 1997 |
| Pyrazoloazepino-substituted oximes, having the formula ##STR1## wherein R is ##STR2## where R.sup.5 is --(CH.sub.2).sub.c -- and c is 3-6 are disclosed. These compounds are useful for the treatment of atherosclerosis and hypercholesterolemia. |
| 5594144 |
Tropolone derivatives and pharmaceutical composition thereof for preventing and treating ischemi |
January 14, 1997 |
| The present invention provides novel tropolone derivatives of the formula I ##STR1## wherein R.sub.10 is a substituted or unsubstituted piperazinyl or benzothiazolidinyl group, and pharamaceutical compositions thereof. These compounds are useful for the prevention and treatment of is |
| 5594140 |
Imidazo[1,5-A]quinolines for treatment of anxiety and sleep disorders |
January 14, 1997 |
| Imidazo[1,5-a]quinolines of formula (I) which are useful pharmaceutical agents for the treatment of anxiety, sleep disorders, panic states, convulsions and muscle disorders. ##STR1## |
| 5594024 |
Centrally actig substituted phenylazacycloalkanes |
January 14, 1997 |
| A compound or Formula I ##STR1## or a pharmaceutically acceptable salt thereof wherein n is 1 or 2; R.sup.1 and R.sup.2 are independently H (provided only one is H at the same time), --OH, CN, CH.sub.2 CN, 2- or 4-CF.sub.3, CH.sub.2 CF.sub.3, CH.sub.2 CHF.sub.2, CH.dbd.CF.sub.2, |
| 5593980 |
Arylmethylphosphonates and phosphonic acids useful as anti-inflammatory agents |
January 14, 1997 |
| This invention provides a new use of acids, esters, and salts of arylmethylphosphonates of Formula I, ##STR1## or a phosphonic acid of Formula II ##STR2## and derivatives as anti-inflammatory and anti-arthritic agents. Representative compounds include 4-dodecyloxybenzylphosph |
| 5583106 |
Somatotropin for increasing reproductive performance in cattle |
December 10, 1996 |
| This invention provides a method of using somatotropin to enhance the reproductive performance in cattle by commencing administration during the early postpartum period. Following one aspect of the invention, somatotropin (5 mg/day) is administered starting at five days postpartum, c |
| 5578599 |
Stimulation of hair growth with minoxidil and a 5.alpha.-reductase inhibitor |
November 26, 1996 |
| An improved method and composition for promoting hair growth in mammals for treating various forms of alopecia or male pattern baldness comprising the concomitant administration of potassium channel openers, such as minoxidil, cromakalim, pinacidil, or a compound selected frown the class |
| 5574038 |
5,6-cyclicimidazo [1,5-a] Quinoxalines |
November 12, 1996 |
| The invention discloses imidazo[1,5-a]quinoxalines (I) ##STR1## which do not contain an endocyclic carbonyl group that are useful as anxiolytic and sedative/hypnotic agents. |
| 5567722 |
Cyanoguanidines as K-channel blockers |
October 22, 1996 |
| Cyanoguanidine compounds of Formula I and its pharmaceutically acceptable acid addition salts ##STR1## wherein R.sub.1 is hydrogen or methyl;R.sub.2 is C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 alkenyl, C.sub.2 -C.sub.6 alkynyl, C.sub.3 -C.sub.5 cycloalkyl, C.sub.3 -C.sub.5 cycloa |
| 5566828 |
Locking package for a syringe |
October 22, 1996 |
| A locking package structure wherein the package will provide a convenient and safe disposable receptacle for the syringe and the needle thereon and which can then be closed so as to prevent the syringe and needle from being a hazard. The open box receives the used syringe at the bedside |
| 5565571 |
Substituted aryl- and heteroaryl-phenyloxazolidinones |
October 15, 1996 |
| The present invention discloses novel substituted aryl- and heteroarylphenyloxazolidinones which are useful as anti-bacterial agents. More specifically, the substituted aryl- and heteroarylphenyloxazolidinones of the invention are characterized by oxazolidinones having an aryl or het |
| 5565468 |
Pyridino substituted oximes useful as anti-atherosclerosis and anti-hypercholesterolemic agents |
October 15, 1996 |
| Imidazopyridino- and pyrazolopyridino- substituted oximes are disclosed having the formulas ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and a are as described in the claims. for the treatment of atherosclerosis and hypercholesterolemia. |
| 5565441 |
Phosphonoacetic esters and acids as anti-inflammatories |
October 15, 1996 |
| Compounds useful in the treatment of inflammation structurally represented as Formula I ##STR1## one of X or Y is H and the other is selected from the group consisting of: ##STR2## or X and Y are taken together to form a ring selected from the group consisting of: ##STR3# |
| 5563142 |
Diaromatic substituted compounds as anti-HIV-1 agents |
October 8, 1996 |
| The present invention includes diaromatic substituted heterocyclic compounds (III) ##STR1## which are useful in treating individuals infected with the HIV virus. |
