| Patent Number |
Title Of Patent |
Date Issued |
| 7456537 |
Control system for bearingless motor-generator |
November 25, 2008 |
| A control system for an electromagnetic rotary drive for bearingless motor-generators comprises a winding configuration comprising a plurality of individual pole pairs through which phase current flows, each phase current producing both a lateral force and a torque. A motor-generator |
| 7417407 |
Circuit with a switch for charging a battery in a battery capacitor circuit |
August 26, 2008 |
| A circuit for charging a battery combined with a capacitor includes a power supply adapted to be connected to the capacitor, and the battery. The circuit includes an electronic switch connected to the power supply. The electronic switch is responsive to switch between a conducting state |
| 7245952 |
Noninvasive birefringence compensated sensing polarimeter |
July 17, 2007 |
| The present invention relates to a system and method for compensating for the effects of birefringence in a given sample and employs an optical birefringence analyzer to sense the real-time birefringence contributions and then provides a feedback signal to a compound electro-optical syst |
| 7164027 |
Aralkyl ester soft drugs |
January 16, 2007 |
| The present invention describes a method for programming a specific course and rate of metabolism for a parent drug compound that leads to an inactive or very weakly active and nontoxic metabolite when the modified drug compound is administered. The parent drug compound is modified by |
| 7105635 |
Cyclic beta-sheet peptides useful as apoptotic/cytotoxic cancer agents |
September 12, 2006 |
| Peptides and pharmaceutical compositions of matter useful as cytotoxic compositions particularly for, but not limited to, treatment of cancers, that includes a synthetic peptide whose amino acid sequence is different from an initial loop of cobra cardiotoxin. |
| 7049326 |
Method and compositions for temporarily incapacitating subjects |
May 23, 2006 |
| A method for modifying at least one non-ester-containing parent compound, and the compounds produced using such method, which compounds are deployed to temporarily incapacitate at least one subject are disclosed. The modified compounds are rapidly metabolized to inactive and non-toxic |
| 6958078 |
Bioartificial intervertebral disc |
October 25, 2005 |
| A bioartificial nucleus pulposus is adapted for replacing at least a portion of a natural nucleus pulposus in an intervertebral disc. The bioartificial nucleus pulposus includes an artificial support structure made from a biodegradable material. The support structure has a plurality |
| 6846937 |
Method for the selective removal of acyl-functionality attached to the 2'-hydroxy-group of pacli |
January 25, 2005 |
| A method for removing acyl-groups appended by an ester linkage to the 2'-hydroxyl group present in paclitaxel-related molecules comprising treatment with alcohol under non-acidic conditions. 2',7-bis-Monochloroacetylpaclitaxel analogs are converted to their corresponding 7-monochloro |
| 6756047 |
Method and compositions for treating persistent pulmonary hypertension using aralkyl ester soft |
June 29, 2004 |
| A method and compositions for treating persistent pulmonary hypertension in human newborns that deploys an intravenous infusion of a modified drug formed by adding one or more of a predetermined chemical arrangement to an efficacious parent drug compound so as to retain efficacy while |
| 6755151 |
Hot-filament chemical vapor deposition chamber and process with multiple gas inlets |
June 29, 2004 |
| A thin film deposition method uses a vacuum confinement cup that employs a dense hot filament and multiple gas inlets. At least one reactant gas is introduced into the confinement cup both near and spaced apart from the heated filament. An electrode inside the confinement cup is used to |
| 6750238 |
Aralkyl ester soft drugs |
June 15, 2004 |
| The present invention describes a method for programming a specific course and rate of metabolism for a parent drug compound that leads to an inactive or very weakly active and nontoxic metabolite when the modified drug compound is administered. The parent drug compound is modified by |
| 6731388 |
Method of measuring surface plasmon resonance using interference structure of reflected beam pro |
May 4, 2004 |
| Changes in optical properties of layered materials are measured by directing an incident wave of finite transverse dimensions toward layered materials under conditions that will produce a propagating surface mode or a waveguide mode in the layered materials. The intensity distribution is |
| 6638839 |
Hot-filament chemical vapor deposition chamber and process with multiple gas inlets |
October 28, 2003 |
| A thin film deposition method uses a vacuum confinement cup that employs a dense hot filament and multiple gas inlets. At least one reactant gas is introduced into the confinement cup both near and spaced apart from the heated filament. An electrode inside the confinement cup is used to |
| 6602891 |
Muscarinic receptor agonists |
August 5, 2003 |
| A compound of Formula (III): ##STR1##wherein X is a linkage independently selected from (CH.sub.2).sub.12 or (CH.sub.2 CH.sub.2).sub.4 O.sub.3 and wherein R.sub.3 is independently selected from H, CH.sub.2 CH.sub.3, COCH.sub.3 or ##STR2##and acid addition salts, solvates and hydrates |
| 6536258 |
Blast load simulation system |
March 25, 2003 |
| A blast load simulation system includes a glass panel having two surfaces. The system also includes a membrane for covering at least one of the two surfaces of the glass panel. The system also includes means for delivering an impulse with a given characteristic to the glass panel through |
| 6498829 |
Method for measurement of physical characteristics of crystals |
December 24, 2002 |
| A method and apparatus to simultaneously measure the diffraction resolution and mosaic spread of macromolecular crystals, are described. The method includes minimizing contributions of an x-ray beam to any reflection angular widths in the crystal, rapidly measuring multi reflection profi |
| 6495680 |
Helices and nanotubes on folding compositions and method of making same |
December 17, 2002 |
| Helical oligomer and polymer compositions that form nanotubes are described. The compositions comprise a plurality of aromatic substituents linked by at least one amide group. The compositions have a curved backbone due to intramolecular hydrogen bonds that rigidify the amide linkage |
| 6376675 |
Muscarinic receptor agonists |
April 23, 2002 |
| A compound of Formula (III): ##STR1##wherein X is a linkage independently selected from (CH.sub.2).sub.12 or (CH.sub.2 CH.sub.2).sub.4 O.sub.3 and wherein R.sub.3 is independently selected from H, CH.sub.2 CH.sub.3, COCH.sub.3 or ##STR2##and acid addition salts, solvates and hydrates |
| 6369081 |
Muscarinic receptor agonists |
April 9, 2002 |
| A compound of Formula (I): ##STR1##wherein R is a linkage independently selected from (CH.sub.2).sub.12 or (CH.sub.2).sub.4 O.sub.3 ; and acid addition salts, solvates and hydrates thereof. The compounds have unusually high affinity for muscarinic receptors, and exhibit agonist activ |
| 6302360 |
Vortex generation for control of the air flow along the surface of an airfoil |
October 16, 2001 |
| Apparatus for generating vortices to control the flow of air across a airfoil of an aircraft includes a series of pressure active regions arranged along the leading edge of the airfoil. The pressure active regions include spaced apart valves connected to a source of vacuum, a control |
| 6298607 |
Venting-membrane system to mitigate blast effects |
October 9, 2001 |
| A venting-membrane system for mitigating blast pressure generated from a blast force on a wall structure. The venting-membrane system having a framework including a plurality of parallel structural members defining a wall structure having an interior surface and an exterior surface. At |
| 6294152 |
Iron(III) complexes as contrast agents for image enhancement in magnetic resonance imaging |
September 25, 2001 |
| A compound of formula (I): ##STR1##wherein, R.sub.1 is independently selected from methyl and ethyl and R.sub.2 is independently selected from hydrogen, alkyl, and substituted alkyl. The compound is capable of functioning as a ligand and complexing with paramagnetic Fe(III) ion for u |
| 6255540 |
Methods for producing two-substituted glycerols having various levels of protection |
July 3, 2001 |
| A method for producing 2-substituted glycerols having various levels of hydroxy group protection by opening dihydroxyacetone dimer in a nonaqueous, non-protic environment with a composition that initially protects both of the liberated 1,3-dihydroxy groups to form di-ether containing |
| 6146615 |
Contrast agents for image enhancement in magnetic resonance imaging |
November 14, 2000 |
| A compound of formula (I): ##STR1## wherein, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are selected independently from hydrogen, alkyl, and alkyl substituted with one or more --O-- atoms, or where R.sup.1, R.sup.2 and R.sup.3, R.sup.4 are ring residues. The compound is capable of fun |
| 6096767 |
Muscarinic receptor agonists |
August 1, 2000 |
| A compound of Formula (I): ##STR1## wherein R is a linkage independently selected from (CH.sub.2).sub.12 or (CH.sub.2).sub.4 O.sub.3 ; and acid addition salts, solvates and hydrates thereof. The compounds have unusually high affinity for muscarinic receptors, and exhibit agonist |
| 6011563 |
Computer controlled photoirradiation during photodynamic therapy |
January 4, 2000 |
| A system and method is provided for optimizing a laser light fractionation during photodynamic therapy of a tumor. The tumor is destroyed through the production of singlet oxygen and successful photodynamic therapy treatment requires the maintenance of tumor oxygen above a specified crit |
| 6003321 |
Open flow helium cryostat system and related method of using |
December 21, 1999 |
| An open flow helium cryostat system for cooling a sample crystal to be examined using X-ray diffraction, neutron diffraction, or a similar method. The cryostat system including a primary helium supply to provide a first stream of liquid helium onto the sample crystal and a secondary |
| 5982143 |
Battery equalization circuit with ramp converter and selective outputs |
November 9, 1999 |
| An electronic battery equalization circuit that equalizes the voltages of a plurality of series connected batteries in a battery pack. The current waveform is in the shape of a ramp for providing zero current switching. The transformer has a primary winding circuit and at least one secon |
| 5925415 |
Electroless plating of a metal layer on an activated substrate |
July 20, 1999 |
| A method of electroless plating at least one homogeneous metal coating in a predetermined pattern on a solid substrate surface having pendant hydroxy groups. The method includes the steps of providing a first monatomic metal layer in a predetermined pattern on the solid substrate surface |
| 5855616 |
Bioartificial pancreas |
January 5, 1999 |
| An implantable bioartificial pancreas device having an islet chamber containing glucose responsive and insulin-secreting islets of Langerhans or similar hormone secreting cells, one or more vascularizing chambers open to surrounding tissue, a semi-permeable membrane between the islet |
| 5846843 |
Sensor using long range surface plasmon resonance with diffraction double-grating |
December 8, 1998 |
| A long range surface plasmon resonance sensor for use in biological, biochemical or chemical testing. The sensor includes a first dielectric medium and a second dielectric medium having an index of refraction approximately matching the first dielectric medium. A double-grating struct |
| 5844399 |
Battery charger control system |
December 1, 1998 |
| A battery charger control system and method for maximizing output power to a battery. This is achieved by ensuring operation at either the maximum allowable input current or the thermal limit imposed by the battery charger using an on-line controller. In the invention, the thermal limit |
| 5746774 |
Knee joint mechanism for knee disarticulation prosthesis |
May 5, 1998 |
| An improved four-bar knee joint mechanism for use in knee disarticulation prosthesis is shown, including a coupler link forming a negative angle with the horizontal when said knee joint mechanism is in its stance position, an anterior link, a fixed link in a horizontal position when |
| 5731890 |
Aromatic rings with rotated adjacent chromophores |
March 24, 1998 |
| A compound having nonlinear optical properties of the general formula:wherein, n represents a whole number; R.sup.1, R.sup.1, R.sup.3 and R.sup.4 groups are independently selected from H, branched aliphatic, straight chain aliphatic, branched silane or straight chain silane; Ar.sup.1 and |
| 5726179 |
Muscarinic agonists |
March 10, 1998 |
| A muscarinic agonist compound having the formula (I) or (II) below or a pharmaceutically acceptable salt thereof: ##STR1## where R is (trans) 3-methyl-2-penten-4-ynyl, (cis)3-methyl-2-penten-4-ynyl, 2-butynyl, 2-methylbutenyl, 3-methylpropynyl, phenylpropynyl, butynyl; or ##S |
| 5693632 |
Method of use of diels alder adducts of vinyl porphyrin metal complexes |
December 2, 1997 |
| Families of Diels Alder adducts and of metal complexes of Diels Alder adducts, which are useful as particularly active compounds for use in photodynamic therapy, are disclosed. The Diels Alder adducts and a preferred family of metal complexes have the structures of Formulas 1, 2, 3 a |
| 5679350 |
Method of delivery of a medicament to a cancer cell using a pathway of plasminogen activator mat |
October 21, 1997 |
| A method of delivering a medicament to the surface of a cancer cell and transferring the medicament into the cancer cell using an activated plasminogen activator material such as a plasminogen activator inhibitor type-1 or type-2 (PAI-1, PAI-2). The medicament is coupled to PAI-1 or |
| 5674289 |
Bioartificial pancreas |
October 7, 1997 |
| An implantable bioartificial pancreas device having an islet chamber containing glucose responsive and insulin-secreting islets of Langerhans or similar hormone secreting cells, one or more vascularizing chambers open to surrounding tissue, a semi-permeable membrane between the islet |
| 5666041 |
Battery equalization circuit with ramp converter |
September 9, 1997 |
| An electronic battery equalization circuit that equalizes the voltages of a plurality of series connected batteries in a battery pack. The current waveform is in the shape of a ramp for providing zero current switching. The ramp converter power circuit has at least one semiconductor devi |
| 5665834 |
Method of polymerizing alpha-olefins with boryl zirconocene organic 1,1-dimetallic compound cata |
September 9, 1997 |
| Boron-zirconium 1,1,-dimetallic organic compounds useful in organic synthesis such as the preparation of alpha-borobromanes. The boron-zirconium compounds include boron and zirconiun, and in particular the synthesis, structure and reactivity of E-chlorobis(cyclopentadienyl)- [1-(4,4, |
| 5663350 |
Process for the preparation of intermediates useful for the synthesis of histamine receptor anta |
September 2, 1997 |
| The present invention relates to a novel process for the preparation of highly potent histamine receptor antagonists, in particular histamine H.sub.3 -receptor antagonists. Also disclosed is a novel process for the preparation of intermediates useful in the preparation of histamine r |
| 5639775 |
4-[4'-piperodinyl or 3'-pirrolidinyl] substituted imidazoles as H.sub.3 -receptor antagonists an |
June 17, 1997 |
| Diazolyl compounds having activity as histamine H3-receptor antagonists, pharmaceutical compositions and methods of using such compounds for treating cognitive disorder or attention or arousal deficit. |
| 5633382 |
Histamine H.sub.3 -receptor antagonists and therapeutic uses thereof |
May 27, 1997 |
| The present invention provides novel compounds having activity as histamine H.sub.3 -receptor antagonists. The novel compounds include 4-imidazolyl-N-substituted pyrrolidines, piperidines, and cycloheptimides. The preferred compounds are 4-imidazolyl-N-(cycloalkyl/aryl-alkyl-carbonyl |
| 5618818 |
Muscarinic agonist compounds |
April 8, 1997 |
| A muscarinic agonist compound having the structure (I) or (II): ##STR1## where R is methyl or dimethylamino; or ##STR2## where R' is dimethylamino. |
| 5587394 |
Production and use of diels alder adducts of vinyl porphyrins, of metal complexes thereof, and o |
December 24, 1996 |
| Families of Diels Alder adducts and of metal complexes of Diels Alder adducts, which are useful as particularly active compounds for use in photodynamic therapy, are disclosed. The Diels Alder adducts and a preferred family of metal complexes have the structures of Formulas 1, 2, 3 a |
| 5494656 |
Second sphere complexes as relaxation agents for image enhancement in magnetic resonance imaging |
February 27, 1996 |
| A second sphere contrast enhancing agent for magnetic resonance imaging comprises a paramagnetic metal ion having catecholate ligands coordinated thereto and having water molecules hydrogen bonded to the catecholate ligands. |
| 5486526 |
Histamine H.sub.3 -receptor antagonists and therapeutic uses thereof |
January 23, 1996 |
| The present invention is directed to compounds of the class of piperidyl-imidazole derivative histamine H.sub.3 -receptor antagonists. Such compounds have affinity for histamine H.sub.3 -receptor, and preferably penetrate the blood-brain barrier. The compounds can block the soporific |
| 5471378 |
AC to DC converter system with ripple feedback circuit |
November 28, 1995 |
| A nonlinear ripple feedback circuit for use with a current-sourced rectifier system with an inductor input filter. The nonlinear ripple feedback circuit eliminates the oscillation of the rectifiers and improves the line-current waveform by sensing of and compensating for any amplitude |
| 5468889 |
Boryl zirconocene organic 1,1-dimetallic compounds |
November 21, 1995 |
| Boron-zirconium 1,1,-dimetallic organic compounds useful in organic synthesis such as the preparation of alpha-bromoboranes. The boron-zirconium compounds include boron and zirconiun, and in particular the synthesis, structure and reactivity of E-chlorobis(cyclopentadienyl)- [1-(4,4, |
| 5451980 |
Liquid crystal flat panel color display with surface plasmon scattering |
September 19, 1995 |
| A flat panel color display is provided in which white collimated light incident on a light coupling means having a metal layer and a liquid crystal layer formed on a surface of the coupling means produces a colored spot of light at the interface of the metal layer and liquid crystal laye |
