| Patent Number |
Title Of Patent |
Date Issued |
| 7094391 |
Compositions and methods for administering Borrelia burgdorferi antigens |
August 22, 2006 |
| Mucosal administration of OspA and compositions therefor are disclosed and claimed. More particularly, oral administration of OspA and compositions therefor for eliciting an immunological response against Borrelia burgdorferi, such as a protective response preventive of Lyme disease are |
| 7094358 |
Ultra-low shrinkage composite resins based on blended nematic liquid crystal monomers |
August 22, 2006 |
| Resin blends comprising liquid crystal monomers and secondary monomers useful to blend with liquid crystal monomers to maintain a nematic state under processing conditions while maintaining low cute shrinkage, particularly suitable for use in dental resin composites. |
| 6923965 |
Modulators of polysaccharides and uses thereof |
August 2, 2005 |
| The present invention provides peptides with a specific affinity for glycosaminoglycan molecules. These peptides may have any number of functions, including but not limited to use as inhibitors of glycosaminoglycan-mediated processes, enhancers of glycosaminoglycan-mediated processes |
| 6852696 |
Inhibitors of glycosaminoglycans |
February 8, 2005 |
| The present invention provides peptide derivatives with a specific affinity for glycosaminoglycan molecules. These peptide derivatives include multimers as well as chemically modified peptides and may be prepared by a variety of methods. The peptides of the invention have numerous functi |
| 6824760 |
Imaging agents, precursors thereof and methods of manufacture |
November 30, 2004 |
| Compounds of formula (I) and (II): ##STR1##wherein groups R.sub.1, R.sub.2, RE, PG.sub.1 and PG.sub.2 have the definitions provided in the specification, methods of manufacture and methods of use. |
| 6677506 |
DNA coding for a Mg2+/H+ or Zn2+/H+ exchanger and transgenic plants expressing same |
January 13, 2004 |
| An isolated DNA molecule is provided coding for a polypeptide of the 11-12 transmembrane domain transporter family having a Mg.sup.2+ /H.sup.+ or Zn.sup.2+ /H.sup.+ exchange activity, herein designated MHX. The genomic MHX DNA was isolated from Arabidopsis thaliana cv. C-24. Transgenic p |
| 6653285 |
Modulators of polysaccharides and uses thereof |
November 25, 2003 |
| The present invention provides peptides with a specific affinity for glycosaminoglycan molecules. These peptides may have any number of functions, including but not limited to use as inhibitors of glycosaminoglycan-mediated processes, enhancers of glycosaminoglycan-mediated processes |
| 6634790 |
Tomotherapy treatment table positioning device |
October 21, 2003 |
| An integrated positioning device for a tomotherapy treatment couch is disclosed. The integrated positioning device has a central frame, two positioning tables, and an attachment arm. The central frame is mounted on the base of the tomotherapy treatment couch. The positioning tables p |
| 6602702 |
Detection system based on an analyte reactive particle |
August 5, 2003 |
| A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles ar |
| 6585802 |
Mixed matrix membranes and methods for making the same |
July 1, 2003 |
| Mixed matrix membranes capable of separating carbon dioxide from mixtures including carbon dioxide and methane, and processes for purifying methane using the membranes, are disclosed. The membranes are preferably polymer membranes that include discrete carbon-based molecular sieve partic |
| 6565631 |
High carbon content filamentary membrane and method of making the same |
May 20, 2003 |
| A high carbon content membrane and method for making the same are disclosed. The carbon membrane includes an asymmetric hollow filamentary carbon membrane, including a partial carbonization product of an asymmetric hollow filament including an aromatic imide polymer material. The car |
| 6562110 |
Carbon molecular sieves and methods for making the same |
May 13, 2003 |
| Mixed matrix membranes capable of separating carbon dioxide from mixtures including carbon dioxide and methane, and processes for purifying methane using the membranes, are disclosed. The membranes are preferably polymer membranes, that include discrete carbon-based molecular sieve parti |
| 6503295 |
Gas separations using mixed matrix membranes |
January 7, 2003 |
| Mixed matrix membranes capable of separating carbon dioxide from mixtures including carbon dioxide and methane, and processes for purifying methane using the membranes, are disclosed. The membranes are polymer membranes with a selective layer thickness of between about 1000 Angstroms to |
| 6498942 |
Optoacoustic monitoring of blood oxygenation |
December 24, 2002 |
| An optoacoustic apparatus is disclosed which includes a radiation source of pulsed radiation and a probe having a front face to be placed in close proximity to or in contact with a tissue site of an animal body. The probe further includes a plurality of optical fibers terminating at the |
| 6488963 |
Hot-melt extrudable pharmaceutical formulation |
December 3, 2002 |
| The present invention relates to pharmaceutical formulations comprising a hot-melt extrudable mixture of a therapeutic compound and a high molecular weight poly(ethylene oxide) in an essentially non-film like preparation. In some embodiments, the formulation further comprises poly(ethyle |
| 6451769 |
Compositions and methods for administering Borrelia DNA |
September 17, 2002 |
| Disclosed is a vaccine against Lyme Disease or its causative agent Borrelia burgdorferi (sensu stricto or sensu lato) containing a plasmid a DNA encoding a promoter for driving expression in a mammalian cell, DNA encoding a leader peptide for facilitating secretion/release of a proka |
| 6361954 |
Methods of immunoassay for human CDC6 |
March 26, 2002 |
| The invention pertains to novel genes which function in the regulation of DNA replication and/or entry of a cell into mitosis. Tile invention also pertains to novel proteins encoded by the genes described herein, antibodies which bind the encoded protein, and homologs of the novel genes |
| 6299669 |
Process for CO2/natural gas separation |
October 9, 2001 |
| The invention includes a process for separating CO.sub.2 from natural gas including: contacting a mixture of CO.sub.2 and natural gas with a first side of a carbon membrane in a manner to cause a portion of the mixture to pass through the carbon membrane to a permeate side. The resulting |
| 6235481 |
Polynucleotides encoding calpain 10 |
May 22, 2001 |
| The present invention relates generally to the field of diabetes. More particularly, it concerns the identification of genes responsible for NIDDM1 for use in diagnostic and therapeutic applications. The present invention demonstrates that the NIDDM1 locus is, in fact, the calpain 10 |
| 6207941 |
Method and apparatus for rapid drying of coated materials with close capture of vapors |
March 27, 2001 |
| A method and apparatus for the removing solvents from coated materials while capturing evaporated vapors in a confined space and maintaining non-explosive conditions within the space. Microwave energy may be applied to a coated material as the coated material passes through a cavity |
| 6046307 |
Modulation of mammalian telomerase by peptide nucleic acids |
April 4, 2000 |
| The invention relates to peptide nucleic acids that inhibit telomerase activity in mammalian cells. |
| 6015710 |
Modulation of mammalian telomerase by peptide nucleic acids |
January 18, 2000 |
| The invention relates to peptide nucleic acids that modulate telomerase activity in mammalian cells. |
| 6013853 |
Continuous release polymeric implant carrier |
January 11, 2000 |
| Biodegradable, porous, polymeric implant material provides substantially continuous release of bioactive agent during in vivo use. Bioactive agent is initially released in amounts that are less than degradation rate of polymer, thereby promoting migration of cells into material. Later la |
| 6004939 |
Methods for modulation and inhibition of telomerase |
December 21, 1999 |
| It was found that normal human stem cells produce a regulated non-processive telomerase activity, while cancer cells produce a processive telomerase activity. Nucleotide analogs, such as 7-deaza-2'-deoxyquanosine-5'-triphosphate (7-deaza-dGTP) were found to be substrates for processi |
| 5998154 |
Somatostatin receptor peptide antigens and antibodies |
December 7, 1999 |
| Peptide antigens derived from the carboxy terminus of somatostatin receptors and antibodies produced using the peptide antigens. The anti-somatostatin receptor antibodies are specific for a receptor subtype and are useful in characterizing receptor subtypes expressed by tissues. |
| 5989807 |
Detecting cancerous conditions by assaying for telomerase activity |
November 23, 1999 |
| Methods and kits are provided for diagnosis of specific cancerous conditions. The invention features a method for diagnosis of a condition in a patient associated with an elevated level of telomerase activity within a cell. The method involves determining the presence or amount of te |
| 5962413 |
Treatment of uterine contractility disorders with a nitric oxide synthase substrate and/or donor |
October 5, 1999 |
| Dysmenorrhea, disfunctional uterine bleeding, preterm labor and postpartum labor in female mammals are treated by inhibiting uterine contractility by administering thereto a nitric oxide synthase substrate, a nitric oxide donor or both, optionally in combination with one or more of a |
| 5948762 |
Treatment of uterine contractility disorders with a nitric oxide synthase substrate and/or donor |
September 7, 1999 |
| Dysmenorrhea, disfunctional uterine bleeding, preterm labor and postpartum labor in female mammals are treated by inhibiting uterine contractility by administering thereto a nitric oxide synthase substrate, a nitric oxide donor or both, optionally in combination with one or more of a |
| 5906987 |
Treatment of male climacteric disorders with nitric oxide synthase substrates and/or donors, in |
May 25, 1999 |
| The symptoms of climacterium in male mammals, e.g., hypertension, cardiovascular disease and osteoporosis, are ameliorated by the administration to an afflicted individual one or both of a nitric oxide substrate and/or nitric acid donor, in combination with an androgen, an aromatase |
| 5902283 |
Antimicrobial impregnated catheters and other medical implants |
May 11, 1999 |
| A non-metallic antimicrobial impregnated medical implant, such as a catheter, and a method for impregnating a non-metallic medical implant with an antimicrobial agent is provided. The method for making the impregnated implant comprises the steps of forming an antimicrobial compositio |
| 5871628 |
Automatic sequencer/genotyper having extended spectral response |
February 16, 1999 |
| An advanced imaging spectrograph system provides for slab-gel DNA sequencing and genotyping with high throughput sequencing. The system is based on the integration of improved electrophoresis structures with an imaging spectrophotometer that records the entire emission spectra along |
| 5691460 |
Epidermal surface antigen gene |
November 25, 1997 |
| The present invention relates to the cloning, sequencing and characterization of a unique human epidermal surface antigen, ESA, and to methods for preparing and using the ESA gene and protein. The ESA gene is mapped to the region 17q11-12, on the long arm of chromosome 17, in the sam |
| 5578122 |
Methods of producing concretes containing class C fly ash that are stable in sulphate environmen |
November 26, 1996 |
| Methods for combining Class C fly ash into cementitious mixtures for producing concretes that are resistant to sulfate-containing environments. In one method, Class C fly ash is intergound with portland cement clinker and gypsum to produce a cementitions mixture, which, when combined wit |
| 5545672 |
Treatment of insulin resistance and type 2 diabetes mellitus with a thiol protease inhibitor |
August 13, 1996 |
| Pharmaceutical compositions and methods for treatment of insulin-resistance and diabetes mellitus using thiol protease inhibitors such as E-64. |
| 5519713 |
Integrated circuit having clock-line control and method for testing same |
May 21, 1996 |
| An integrated circuit includes a plurality of interconnected circuit modules having memory elements and logic elements therein. The modules collectively perform the operations of the integrated circuit. However, rather than testing the entire circuit and limiting the degree of fault |
| 5474030 |
Method and apparatus for determining excitants and attractants for the penaeus genus of crustace |
December 12, 1995 |
| Described is a process for determining excitants and attractants for members of the Penaeus genus of Crustacea including but not limited to Penaeus setiferus and Penaeus vannamei, as well as apparatus for carrying out such process. The apparatus for carrying out the process includes |
| 5288502 |
Preparation and uses of multi-phase microspheres |
February 22, 1994 |
| Multi-phase polymeric microspheres containing a molecular compound dispersed in a polymeric matrix are described. Methods for preparing the multi-phase microspheres are also described, which includes a multiple emulsion solvent evaporation technique. Drug loading efficiencies between |
| 5288304 |
Composite carbon fluid separation membranes |
February 22, 1994 |
| The invention provides carbon membranes for use in fluid separation processes, particularly gas separations, which are treated with a coating that provides a protective barrier which significantly limits permeation of water vapor or other impurities such as hydrocarbons without signi |
| 5268973 |
Wafer-scale optical bus |
December 7, 1993 |
| An improved wafer-wide optical bus interconnect is described for use in wafer-scale integration systems. By optically coupling sub-systems on the wafer, faults normally found in electrically based interconnection topologies are avoided. The invention incorporates a planar waveguide w |
| 5219889 |
Dietary supplementation with potassium magnesium citrate |
June 15, 1993 |
| A method for supplementing dietary potassium, magnesium and citrate is disclosed that comprises orally administering an effective amount of potassium magnesium citrate in a single salt. Methods for decreasing urinary calcium and oxalate by the administration of potassium magnesium ci |
| 5160254 |
Apparatus and method for combustion within porous matrix elements |
November 3, 1992 |
| Apparatus for controlled low NO.sub.x combustion. First and second combustion zones are provided, each filled with a porous high temperature resistant matrix, the void spaces of which provide sites at which substantially all of the combustion occurs. The second zone is downstream of |
| 5041203 |
Apparatus and procedure for rotating gel electrophoresis |
August 20, 1991 |
| An apparatus and a procedure for fractionating DNA using agarose gel electrophoresis is provided. To improve resolution by length and conformation, the direction of the electric field impressed upon the sample is changed by rotating the gel. During agarose gel electrophoresis in one |
| 4951286 |
Device and method for squeezed state generation by a coupled system |
August 21, 1990 |
| Squeezed states of light having significant degrees of squeezing are achieved with modest values of atomic density and intracavity electromagnetic (EM) field by a device and method for coupling the EM field within the optical cavity. An oscillatory exchange of excitation then occurs |
| 4944592 |
Device and method for quantum nondemolition measurements using parametric oscillation |
July 31, 1990 |
| Quantum nondemolition measurements are made by back-action evasion obtained by a combination of a parametric oscillation and a conversion of polarizations. A polarization converter (14, 16, 17), such as a Faraday rotator, converts at substantially a single frequency between at least a |
| 4920061 |
Biological magnetic colloids |
April 24, 1990 |
| Colloidal-sized paramagnetic particles are formed with affinity ligands directly adsorbed to their surface. The colloidal-sized particles can form a colloidal disperse phase which is distributed through an aqueous dispersion medium to form a biological magnetic fluid. The fluid can be |
| 4878500 |
Multi-beam tracking for angle error correction in speed of sound estimations |
November 7, 1989 |
| This invention relates to a method for correcting angle error present in in vivo sound velocity estimations. More particularly, this invention relates to a method for estimating the angle of misdirection of a tracked ultrasound beam used in sound velocity measurements in conjunction with |
| 4841217 |
Pulsed generator incorporating output waveform flexibility and a pulsed transformer |
June 20, 1989 |
| A single phase, multipole alternator with inertial and/or electromagnetic energy storage is disclosed. More specifically, the present invention involves a high energy pulsed alternator which is capable of generating a variety of pulse signals by ready modification of the angle between th |
| 4762125 |
Balloon-tipped suction catheter |
August 9, 1988 |
| A balloon-tipped suction catheter, for extirpating and aspirating tracheobronchial secretions from the trachea, endotracheal tube or tracheostomy tube and a method for using such catheter. The catheter preferably embodies an elongated tube with a cannula extending along the elongated |
| 4623703 |
Synthesis of conducting polymers: polybutadienes from disubstituted butynes |
November 18, 1986 |
| A two-step method is disclosed for chemically synthesizing substituted butadiene polymers from 1,4-disubstituted butynes. The first step in the synthesis of the butadiene polymer is the polymerization of 1,4-disubstituted butyne monomers. The substituted butyne polymer which results |
| 4268750 |
Realtime radiation exposure monitor and control apparatus |
May 19, 1981 |
| An apparatus for measuring radiation exposure in realtime by measuring the charge flowing in an external circuit when radiation creates electron hole pairs, and thus allows discharge, of a duo-dielectric detector. |
