| Patent Number |
Title Of Patent |
Date Issued |
| 7446124 |
Wortmannin analogs and methods of using same in combination with chemotherapeutic agents |
November 4, 2008 |
| Novel wortmannin analogs and their use in inhibiting PI-3-kinase activity in mammals and the treatment or prevention of cancer and tumor formation in a subject are described herein. Preferably, the wortmannin analogs may be administered with other chemotherapeutic agents in the treatment |
| 6974791 |
Endothelial specific targeting |
December 13, 2005 |
| Peptide motifs which define specificity of tumor-derived endothelial cells. These peptides possess a charge motif of positive-positive-hydrophobic which is important in determining the specificity of binding to tumor-derived endothelium. The specific molecular peptide motifs will fac |
| 6905667 |
Polymer and method for using the polymer for noncovalently functionalizing nanotubes |
June 14, 2005 |
| A new, non-wrapping approach to functionalizing nanotubes, such as carbon nanotubes, in organic and inorganic solvents is provided. In accordance with certain embodiments, carbon nanotube surfaces are functionalized in a non-wrapping fashion by functional conjugated polymers that include |
| 6744727 |
Apparatus and method for spare capacity allocation |
June 1, 2004 |
| A method is given for deriving a backup path routing spare capacity template that is feasible, scalable, adaptive, much faster, and near global optimal in redundancy reduction. The method includes determining working paths, aggregating the working paths into a first matrix, determini |
| 6673937 |
Syntheses and methods of use of new antimitotic agents |
January 6, 2004 |
| Oxidative cyclization of bis-naphthyl ethers allows concise total syntheses of palmarumycin CP.sub.1 and deoxypreussomerin A in 8-9 steps and 15-35% overall yield from 5-hydroxy-8-methoxy-1-tetralone. A small library of palmarumycin analogs was created. Biological evaluation of these |
| 6447265 |
Magnetically suspended miniature fluid pump and method of designing the same |
September 10, 2002 |
| A rotary pump for pumping fluids through a patient having a housing with an internal region, a stator member and an impeller positioned within the housing and having impeller blades, wherein the impeller is magnetically suspended and rotated, and wherein the geometric configuration of th |
| 6438419 |
Method and apparatus employing a scaling exponent for selectively defibrillating a patient |
August 20, 2002 |
| A defibrillator, which selectively delivers a defibrillation pulse to a patient, includes electrodes adapted for placement on the patient, a monitoring circuit for providing an electrocardiogram (ECG) of the patient, and a defibrillation pulse generator having an energy store for del |
| 6392055 |
Synthesis and biological evaluation of analogs of the antimitotic marine natural product curacin |
May 21, 2002 |
| The present invention provides an efficient synthetic strategy for the preparation of analogs that incorporate important structural elements of the marine natural product curacin A, the compositions and various uses of the compositions. The most active of these compounds at nanomolar |
| 6224859 |
Composition containing immature mammalian dendritic cells for enhancing tolerogenicity to foreig |
May 1, 2001 |
| A novel transplantation method for enhancing tolerogenicity in a host mammal to a transplant graft specimen from a donor mammal is disclosed. According to this method, immature mammalian dendritic cells propagated in the presence of a cytokine are administered to the host mammal in advan |
| 6017699 |
PCR identification and quantification of important Candida species |
January 25, 2000 |
| The subject invention relates to a set of DNA primers which, when utilized in conjunction with the polymerase chain reaction (PCR) assay, can amplify and speciate DNA from five medically important Candida species. Furthermore, the PCR amplified products, generated by the primers, can |
| 5876692 |
Non-lethal methods for conditioning a recipient for bone marrow transplantation |
March 2, 1999 |
| The present invention relates to non-lethal methods of conditioning a recipient for bone marrow transplantation. In particular, it relates to the use of nonlethal doses of total body irradiation, total lymphoid irradiation cell type-specific antibodies, especially antibodies directed |
| 5869305 |
Recombinant viral vector system |
February 9, 1999 |
| The present invention relates to a system for replication and encapsidation of recombinant DNA fragments into virus particles comprised of adenovirus associated viral (AAV) capsid proteins. The invention provides a means of obtaining recombinant viral stocks that may be used to treat pat |
| 5774088 |
Method and system for warning birds of hazards |
June 30, 1998 |
| A hazard warning system radiates pulses of microwave energy in the frequency range of 1 GHz to about 40 GHz to alert and warn target flying birds of the presence of wind turbine electrical generators, power distribution systems, aircraft, and other protected areas from hazardous intr |
| 5772994 |
Hematopoietic facilitatory cells and their uses |
June 30, 1998 |
| The present invention relates to mammalian hematopoietic facilitatory cells (FC). In particular, it relates to the isolation, characterization and uses of the FC. The FC of the present invention can be distinguished from all other known bone marrow cells by their morphology, cell surface |
| 5714511 |
Selective prevention of organ injury in sepsis and shock using selection release of nitric oxide |
February 3, 1998 |
| A method for the treatment of mammalian tissue injured or at risk of injury during sepsis or shock including the administration to a mammal a diazeniumdiolate which releases a therapeutically effective amount of nitric oxide sufficient to protect the tissue from sepsis- or shock-indu |
| 5501680 |
Boundary and proximity sensor apparatus for a laser |
March 26, 1996 |
| A laser operation and control system preferably comprising a laser adapted to be grasped by a user and freely passed over a treatment area, control circuitry for activating and deactivating the laser, at least one boundary sensor operable to transmit a signal to the control circuitry to |
| 5221652 |
Methanol synthesis using a catalyst combination of alkali or alkaline earth salts and reduced co |
June 22, 1993 |
| The present invention relates to a novel route for the synthesis of methanol, and more specifically to the production of methanol by contacting synthesis gas under relatively mild conditions in a slurry phase with a catalyst combination comprising reduced copper chromite and basic al |
| 5049347 |
Method for producing doubly oriented polymers |
September 17, 1991 |
| A process for the solid phase preparation of doubly oriented synthetic polymeric material from an orientable amorphous but crystallizable or a semicrystalline thermoplastic polymeric workpiece comprising: (a) presenting the conditioned workpiece, at the entry mode of an opposing pair |
| 4946938 |
A process for the catalytic synthesis of polyphosphazenes |
August 7, 1990 |
| The present invention relates to an improved process for the synthesis of polyphosphazenes in which catalytic amounts of a compound selected from the group consisting of toluenesulfonic acid, sulfabenzoic acid, ammonium sulfamate and sulfamic acid, and preferably an effective amount of a |
| 4883334 |
Optical selector switch |
November 28, 1989 |
| The present invention pertains to an optical selector switch. The optical selector switch includes an optical waveguide means, and M means for producing light that can be transmitted through the optical waveguide means with M being greater than or equal to 2. The M light producing means |
| 4208399 |
Tolyl isocyanate test antigens, methods for their preparation and use in detecting diisocyanates |
June 17, 1980 |
| An antigen and a method for its preparation and use in detecting antibody to a selected diisocyanate is provided by reacting the monoisocyanate derivative of the diisocyanate with a protein, incubating the antigen on a paper disc with test serum in the presence of a buffer and anti-IgE- |
