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The Trustees of Columbia University in the City of New York Patents
Assignee:
The Trustees of Columbia University in the City of New York
Address:
New York, NY
No. of patents:
767
Patents:


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Patent Number Title Of Patent Date Issued
RE39967 Solid-state photoelectric device January 1, 2008
A solid state photovoltaic device is formed on a substrate and includes a photoactive channel layer interposed between a pair of electrodes. The photoactive channel layer includes a first material which absorbs light and operates as a hole carrier. Within the first material are nanop
RE38506 Potent inducers of terminal differentiation and methods of use thereof April 20, 2004
The present invention provides the compound having the structure: ##STR1##wherein each of R.sub.1 and R.sub.2 are independently the same as or different from each other; when R.sub.1 and R.sub.2 are the same, each is a substituted or unsubstituted arylamino, cycloalkylamino, pyridineamin
RE35093 Systems and methods for coding even fields of interlaced video sequences November 21, 1995
In accordance with the invention, a method, for coding multi-mode predictive interpolative coded fields of video, includes the steps of:(a) providing a current field of interlaced pixel data, and past and future fields of such data;(b) providing estimated pixel data at omitted line positions
7619656 Systems and methods for de-blurring motion blurred images November 17, 2009
Systems and methods for providing a substantially de-blurred image of a scene from a motion blurred image of the scene are disclosed. An exemplary system includes a primary detector for sensing the motion blurred image and generating primary image information representing the blurred
7615554 Erastin and erastin binding proteins, and uses thereof November 10, 2009
The invention relates to methods of screening for binding partners, especially binding partners essential for the biological activity of erastin (e.g. VDACs such as VDAC3). The invention also provides reagents and methods for effective killing of cancer cells with erastin and related
7614748 Systems and methods for displaying three-dimensional images November 10, 2009
Systems and methods for displaying three-dimensional (3D) images are described. In particular, the systems can include a display block made from a transparent material with optical elements three-dimensionally disposed therein. Each optical element becomes luminous when illuminated b
7610384 Network telephony appliance and system for inter/intranet telephony October 27, 2009
A network appliance (100) is provided having a network controller subsystem (110) for coupling the appliance (100) to a data network for providing and receiving data packets to and from a packet data network. A digital signal processing subsystem (120) is coupled to the network contr
7602320 Systems and methods for companding ADC-DSP-DAC combinations October 13, 2009
Systems and methods for resizing a signal for use with a fixed-point DSP are provided. More specifically, a process called companding is used in conjunction with fixed-point devices to resize a signal to make use of the available range of these devices. In some embodiments, companding is
7588566 Electrothermal instrument for sealing and joining or cutting tissue September 15, 2009
An instrument and method are provided for sealing and joining or hemostatically dividing tissue, which is particularly suitable for laparoscopic and endoscopic surgery. The instrument makes use of the controlled application of a combination of heat and pressure to seal adjacent tissu
7588550 Systems and methods of blood-based therapies having a microfluidic membraneless exchange device September 15, 2009
The present invention is directed to devices, systems and methods for removing undesirable materials from a sample fluid by contact with a second fluid. The sample fluid flows as a thin layer adjacent to, or between, concurrently flowing layers of the second fluid, without an interve
7582740 Methods and kits for detecting SARS-associated coronavirus September 1, 2009
The present invention provides a synthetic nucleic acid sequence comprising 10-30 nucleotides of the N gene region and/or the 3' non-coding region of the SARS-associated coronavirus genome, and a synthetic nucleic acid sequence comprising 10-30 nucleotides of a nucleic acid sequence
7579969 Systems and methods for creating and using a conditioning signal August 25, 2009
Systems and methods for creating and using a conditioning signal are provided. In some embodiments, systems for creating a conditioning signal providing information regarding an input signal are provided, wherein the systems comprise: a signal conditioning developer that receives the inp
7579330 Methods of treating various cancers using melanoma differentiation associated protein-7 August 25, 2009
This invention provides a method for reversing the cancerous phenotype of a cancer cell by introducing a nucleic acid having the melanoma differentiation associated gene (mda-7) into the cell under conditions that permit the expression of the gene so as to thereby reverse the cancero
7563461 Zinc salt compositions for the prevention of dermal and mucosal irritation July 21, 2009
The present invention relates to methods and compositions which employ low concentrations of combinations of zinc salts to prevent the irritation of skin or mucous membranes that may be caused by therapeutic agents, by personal hygiene products, or by various physical, chemical, mechanic
7555840 Omni-directional lens in sundials and solar compasses July 7, 2009
Sundials and solar compasses including are disclosed. Some embodiments include an omni-directional lens, which can focus a sun beam into a sharp spot with a long depth of field. By projecting the spot onto a cylindrical panel, both the day of the year and the time of the day can be r
7554596 Method and apparatus for recording a sequence of images using a moving optical element June 30, 2009
An imager (200) including a spatially varying optical element (204) which moves while the imager records a sequence of images. The optical element (204) can be an intensity reduction filter, a spectral or polarization filter, or a refractive or reflective element. Because the optical
7548094 Systems and methods for on-chip signaling June 16, 2009
Systems and methods for on-chip signaling are disclosed. In some embodiments, an integrated circuit having on-chip signaling between a first component and a second component includes, a differential interconnect capable of coupling the first component to the second component, a drive
7544678 Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) June 9, 2009
The present invention provides novel 1,4-benzothiazepine intermediates and derivatives, methods for synthesizing same, and methods for assaying same. The present invention also provides methods for using these novel compounds to limit or prevent a decrease in the level of RyR2-bound
7542622 Spatio-temporal treatment of noisy images using brushlets June 2, 2009
Treatment and mitigation or reduction of noise effects in noisy image data and data sets is described. Various aspects include treatment of noisy data with brushlet transforms and thresholding operations along with a favorable sequence of spatial and temporal processing and thresholding.
7537779 Antimicrobial medical devices May 26, 2009
The present invention provides for antimicrobial medical articles prepared by a method comprising treating a surface of the medical article with a solution consisting essentially of one or more solvents and a mixture of chlorhexidine free base and a water-soluble chlorhexidine salt, at a
7534905 Reagents for asymmetric allylation, aldol, and tandem aldol and allyation reactions May 19, 2009
A new class of reagents and method of use of the reagents in the reaction of the reagents with electrophilic compounds. The invention in one embodiment is directed to a method for the formation of an alcohol of the formula (I). The method includes reacting a reagent of the formula (II)
7534221 Devices and methods for protecting against distal embolisms May 19, 2009
Endovascular intervention methods entail creating a temporary capillary block in the vasculature of at least a portion of a patient's organ, such as a hemisphere of the patient's brain, the capillary block essentially blocking blood flow through capillaries in the portion of the patient'
7532656 All-silicon raman amplifiers and lasers based on micro ring resonators May 12, 2009
Devices for generating a laser beam are disclosed. The devices include a silicon micro ring having at least one silicon optical waveguide disposed at a distance from the micro ring. The radius and the cross-sectional dimension of the microring, the cross-sectional dimension of the wa
7510638 Method of electric field assisted deposition of films of nanoparticles March 31, 2009
The present invention is directed to a method for depositing unpatterned or selectively patterned nanoparticle films of controlled thickness on the respective film deposition surface of each of a pair of electrodes. In the present method, a pair of electrodes, each having a conducting
7509959 Method and apparatus for circulatory valve repair March 31, 2009
An apparatus for the repair of a cardiovascular valve has leaflets comprising a grasper capable of grabbing and co-apting the leaflets of the valve. In a preferred embodiment the grasper has jaws that grasp and immobilize the leaflets, and then a fastener is inserted to co-apt the le
7507792 MDA-7 proteins and methods of use thereof March 24, 2009
This invention provides a method of generating a subtracted cDNA library of a cell comprising: a) generating a cDNA library of the cell; b) isolating double-stranded DNAs from the cDNA library; c) releasing the double-stranded cDNA inserts from the double-stranded DNAs; d) denaturing
7498134 HAUSP-Mdm2 interaction and uses thereof March 3, 2009
The present invention provides methods for diagnosing neoplasia, assessing the efficacy of therapy to treat neoplasia, assessing the prognosis of a subject who has neoplasia, and treating neoplasia. The present invention also provides a kit for use in detecting neoplasia. The present inv
7495699 Imaging method and system February 24, 2009
A method and system for accurately imaging scenes having large brightness variations. If a particular object in the scene is of interest, the imager exposure setting is adjusted based on the brightness of that object. For high dynamic range imaging of an entire scene, two imagers wit
7494972 Method for inhibiting accelerated atherosclerosis in a subject suffering from hypercholesterolem February 24, 2009
The present invention provides for a method to prevent accelerated atherosclerosis in a subject predisposed thereto which comprises administering to the subject a polypeptide derived from soluble receptor for advanced glycation endproduct in an amount effective to prevent accelerated
7490268 Methods and systems for repairing applications February 10, 2009
In accordance with the present invention, computer implemented methods and systems are provided that allow an application to automatically recover from software failures and attacks. Using one or more sensors, failures may be detected in the application. In response to detecting the fail
7489727 Method and device for online dynamic semantic video compression and video indexing February 10, 2009
A technique for semantic video compression is shown in block (120). Uncompressed video data (210), including a plurality of video data segments (S1, S2, . . . Sn), are organized into two or more buffer slots (220), such that each of the two or more buffer slots is filled with one or
7487641 Microfabricated rankine cycle steam turbine for power generation and methods of making the same February 10, 2009
In accordance with the present invention, an integrated micro steam turbine power plant on-a-chip has been provided. The integrated micro steam turbine power plant on-a-chip of the present invention comprises a miniature electric power generation system fabricated using silicon micro
7487544 System and methods for detection of new malicious executables February 3, 2009
A system and methods for detecting malicious executable attachments at an email processing application of a computer system using data mining techniques. The email processing application may be located at the server or at the client or host. The executable attachments are filtered from
7482138 PAK5-related compositions and methods January 27, 2009
This invention provides nucleic acids encoding human PAK5-related proteins, and provides the encoded proteins. This invention also provides vectors, cells and compositions. Finally, this invention provides methods of inducing and inhibiting various cellular processes using the instant
7474237 Circuits and methods for using error correction in power amplification and signal conversion January 6, 2009
Circuits and methods for using error correction in power amplification and signal conversion are disclosed herein. In some embodiments, methods for using error correction in power amplification and signal conversion including converting an input signal into a digital signal; amplifying
7473788 Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof January 6, 2009
The subject invention provides compounds having the structure: ##STR00001## wherein R.sub.1 is H, OH, a photoactivatable moiety, a fluorescent moiety, or a radioactive moiety; R.sub.2 is H, OH, a photoactivatable moiety, a fluorescent moiety, or a radioactive moiety; R.sub.3 is H or
7473766 PAK4-related antibodies January 6, 2009
This invention provides an isolated mammalian nucleic acid molecule encoding a PAK4 serine/threonine kinase. This invention provides an isolated nucleic acid molecule encoding a mutant homolog of the mammalian PAK4 serine/threonine kinase whose amino acid sequence is set forth in FIG
7470516 Cross reactive arrays of three-way junction sensors for steroid determination December 30, 2008
This invention provides analyte sensitive oligonucleotide compositions for detecting and analyzing analytes in solution, including complex solutions using cross reactive arrays of analyte sensitive oligonucleotide compositions.
7464712 Method and apparatus for circulatory valve repair December 16, 2008
An apparatus for the repair of a cardiovascular valve has leaflets comprising a grasper capable of grabbing and co-apting the leaflets of the valve. In a preferred embodiment the grasper has jaws that grasp and immobilize the leaflets, and then a fastener is inserted to co-apt the le
7463362 Digital signal processor-based detection system, method, and apparatus for optical tomography December 9, 2008
The present invention provides systems, methods and apparatuses that perform digital detection for use in optical tomography. Methods and systems are provided in which digital lock-in detection is performed using an algorithm that employs a phase-independent quadrature technique. Met
7455978 Protein/solubility folding assessed by structural complementation November 25, 2008
Many proteins, when produced recombinantly, suffer from improper processing, folding and lack normal solubility. Modified proteins, including those indicative of disease states, also can have such defects. The present invention is directed to methods of identifying proper and imprope
7449565 Chimeric tumor suppressor gene and protein November 11, 2008
The present invention relates to chimeric molecules comprising portions of rat PEG-3 ("rPEG-3") and human GADD34 ("hGADD34") having apoptotic activity. It is based, at least in part, on the discovery that a chimeric protein comprising amino acids 1-347 of rat PEG-3 fused with residues
7449309 Methods for desensitizing a subject to an agent November 11, 2008
This invention provides a method of preventing or treating in a subject contact dermatitis which comprises administering to the subject an amount of a compound capable of inhibiting the stem cell factor signaling pathway effective to prevent or treat contact dermatitis so as to thereby
7449163 Method for preparing nanoparticles comprising cerium oxide and zirconium November 11, 2008
This invention provides a method for preparing nanoparticles comprising cerium oxide and zirconium and having a narrow size distribution. The method comprises providing a first aqueous solution comprising zirconium oxychloride and providing a second aqueous solution comprising a first
7448084 System and methods for detecting intrusions in a computer system by monitoring operating system November 4, 2008
A method for detecting intrusions in the operation of a computer system is disclosed which comprises gathering features from records of normal processes that access the files system of the computer, such as the Windows registry, and generating a probabilistic model of normal computer
7446874 Reagents for arsenic meter November 4, 2008
A formulation for preparing water samples for determining arsenic concentration by colorimetry is provided. The chemical reagents in the formulation may be provided as premeasured and premixed tablets or pills. The chemical reagents include sulfamic acid, an oxidizer, and color reage
7442684 Long-acting hormone and growth factor compositions and uses thereof October 28, 2008
This invention provides VEGF-FSH compounds having increased serum half-lives relative to either native VEGF or FSH, in which both VEGF and FSH are biologically active. This invention also provides related compositions and methods for increasing fertility, egg production and spermatog
7440637 Method and apparatus for image mosaicing October 21, 2008
A method and apparatus is provided for capturing images using a camera or other imager having imaging sensitivity characteristics which vary across the imager's viewing angle. The imager's characteristics can be non-uniform with respect to exposure, color sensitivity, polarization se
7440634 Method for de-blurring images of moving objects October 21, 2008
Systems and methods for providing methods are provided for deblurring images, which are blurred due to the movement of objects in the imaged scene. The systems and methods involve separating a moving object component from a static or background component of a primary image. The movin
7436251 System and method for dynamic power-optimization of analog active filters October 14, 2008
A circuit including two operational amplifiers connected in parallel. For the purpose of this explanation, assume that an equivalent input noise of a circuit with one operational amplifier is too high. Where two operational amplifiers, are connected in parallel, the signals from the
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