| Patent Number |
Title Of Patent |
Date Issued |
| RE35212 |
Superconductor magnetic reading and writing heads |
April 16, 1996 |
| Read/write heads for exchanging information with a magnetic media in either vertical or horizontal recording modes include SQUID detectors coupled to the magnetic flux path of the head. Selective use of superconducting material improves the data interchange operating efficiency of the |
| 7623685 |
Biometric signatures and identification through the use of projective invariants |
November 24, 2009 |
| Techniques, systems and methods for obtaining biometric signatures and identification are described. Broadly stated, embodiments of the present invention utilize specified geometric principles to provide means for accurate biometric identification using projective invariant features of |
| 7622549 |
Human telomerase reverse transcriptase polypeptides |
November 24, 2009 |
| The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for |
| 7612733 |
Transition region for use with an antenna-integrated electron tunneling device and method |
November 3, 2009 |
| An electron tunneling device includes a first non-insulating strip and a second non-insulating strip spaced apart from one another such that first and second end portions, respectively, of the first and second non-insulating strips cooperate to form an antenna having an antenna imped |
| 7608611 |
Hsp90 inhibitors, methods of making and uses therefor |
October 27, 2009 |
| The invention provides purified 18,21-didehydro-18,21-dideoxo-18,21-dihydroxy-geldanamycin derivatives, pharmaceutically acceptable salts thereof and prodrugs thereof that are potent Hsp90 binding agents that are useful for the treatment and/or the amelioration of symptoms of cancer |
| 7595686 |
Digital controller for high-frequency switching power supplies |
September 29, 2009 |
| A voltage controller (150), the controller comprising: a voltage comparator (700) operative to provide a digital error signal (152); a compensator (300) operative to determine a digital control signal (154) based on said provided error signal; and a modulator (400) operative to provi |
| 7595060 |
Yeast-antigen compositions methods of making the same |
September 29, 2009 |
| Disclosed is a vaccine that includes a dendritic cell loaded with a yeast vehicle and antigen. Also disclosed are methods of making the vaccine and using the vaccine to elicit cellular and humoral immune responses in a mammal. Additionally, a method to elicit an immune response by ad |
| 7585622 |
Increasing the proliferative capacity of cells using telomerase reverse transcriptase |
September 8, 2009 |
| The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for |
| 7583167 |
High frequency magnetic thin film filter |
September 1, 2009 |
| A layered microstrip device is described, in which at least two layers of different high internal field/high resonance frequency materials serve as the active elements of the device. The device is designed to filter ranges of high frequency electromagnetic waves, and is on a small scale |
| 7572908 |
Cleavable linkers for polynucleotides |
August 11, 2009 |
| In various embodiments of the invention, novel compositions having a polynucleotide bound to a substrate via a cleavable linker are provided, and methods of cleaving a polynucleotide from a substrate are provided. |
| 7572907 |
Methods and compounds for polynucleotide synthesis |
August 11, 2009 |
| Methods of forming polynucleotides are disclosed. |
| 7560437 |
Nucleic acid compositions for eliciting an immune response against telomerase reverse transcript |
July 14, 2009 |
| The present invention is directed to pharmaceutical compositions comprising a telomerase reverse transcriptase polypeptide or a polypeptide homologous to a telomerase reverse transcriptase. The present invention is also directed to pharmaceutical compositions comprising a polynucleot |
| 7521003 |
Functionalized nanostructured lyotropic liquid crystal polymers |
April 21, 2009 |
| The invention provides cross-linked lyotropic liquid crystal (LLC) copolymers having ordered nanometer-sized pores lined with functional groups. The copolymers are formed by copolymerizing LLC monomers with strong LLC character and functionalized monomers with no or weak LLC characte |
| 7517971 |
Muteins of human telomerase reverse transcriptase lacking telomerase catalytic activity |
April 14, 2009 |
| The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for |
| 7510710 |
Compositions of UCP inhibitors, Fas antibody, a fatty acid metabolism inhibitor and/or a glucose |
March 31, 2009 |
| Systems and methods for treating inflammatory and proliferative diseases, and wounds, using as a pharmacon a UCP and/or Fas antibody or other inhibitor, or combination thereof, and a therapeutically acceptable amount of a fatty acid metabolism inhibitor and/or a therapeutically accep |
| 7498394 |
(Meth)acrylic and (meth)acrylamide monomers, polymerizable compositions, and polymers obtained |
March 3, 2009 |
| The present invention provides novel (meth)acrylic and (meth)acrylamide monomers and polymers produced from those monomers. The monomers of the invention each include only a single vinyl functionality and at least one non-vinyl functionality that can be varied to achieve desired mono |
| 7485307 |
Human cystathionine .beta.-synthase variants and methods of production thereof |
February 3, 2009 |
| Human cystathionine .beta.-synthase variants are disclosed, as well as a method to produce recombinant human cystathionine .beta.-synthase and variants thereof. More particularly, the role of both the N-terminal and C-terminal regions of human CBS has been studied, and a variety of t |
| 7482331 |
Diagnosis and treatment of myocardial failure |
January 27, 2009 |
| The invention provides a method of treating myocardial failure in a human. The method comprises administering an effective amount of transgene encoding .alpha.-MHC that directly causes an increase in the quantity of .alpha.-MHC in the myocardial tissue of the heart. |
| 7479772 |
Active current sharing multiphase DC-DC converter |
January 20, 2009 |
| A converter module for use as a phase in a multiphase DC-DC converter having a data bus for transferring current-sharing information is provided. The converter module includes a power stage and a controller. The power stage comprises an input for receiving an input voltage and an out |
| 7470431 |
Use of neurotoxin therapy for treatment of urological-neurological disorders associated with pro |
December 30, 2008 |
| The present invention related to methods for treating neurological-urological conditions associated with prostate cancer or methods of treatment of prostate cancer, which is accomplished by administration of botulinum toxin to the patient. |
| 7456620 |
Determining dead times in switched-mode DC-DC converters |
November 25, 2008 |
| Systems, methods, and apparatuses are disclosed for determining dead-times in switched-mode DC-DC converters with synchronous rectifiers or other complementary switching devices. In one embodiment, for example, a controller for a DC-DC converter determines dead-times for switching de |
| 7455845 |
Use of neurotoxin therapy for treatment of urologic and related disorders related to lowering el |
November 25, 2008 |
| The present invention related to methods for treating neurological-urological conditions, including urinary retention. This is accomplished by administration of a botulinum toxin into the lower urinary tract of a patient with urinary retention, including the bladder or urinary sphinc |
| 7449192 |
Use of neurotoxin therapy for treatment of urologic and related disorders related to neurogenic |
November 11, 2008 |
| The present invention related to methods for treating neurological-urological conditions, including neurogenic bladder dysfunction. This is accomplished by administration of a botulinum toxin into the lower urinary tract of a patient with a neurogenic bladder dysfunction, including t |
| 7445794 |
Methods for treating human proliferative diseases, with a combination of fatty acid metabolism i |
November 4, 2008 |
| The present invention generally relates to systems and methods for treating inflammatory and proliferative diseases, and wounds, using a combination of (1) fatty acid metabolism inhibitors and (2) glycolytic inhibitors and/or UCP and/or Fas inhibitors or antibodies. More particularly |
| 7436595 |
Extended depth of field optical systems |
October 14, 2008 |
| A system for increasing the depth of field and decreasing the wavelength sensitivity and the effects of misfocus-producing aberrations of the lens of an incoherent optical system incorporates a special purpose optical mask into the incoherent system. The optical mask has been designed to |
| 7429387 |
Use of botulinum toxin therapy for treatment of recalcitrant voiding dysfunction |
September 30, 2008 |
| The present invention related to methods for treating neurological-urological conditions. This is accomplished by administration of at least one neurotoxin. |
| 7427496 |
Anti-cancer compounds |
September 23, 2008 |
| The invention provides bradykinin antagonists and pharmaceutically acceptable salts thereof having anti-cancer activity. These anti-cancer compounds are particularly useful for inhibiting the growth of lung and prostate cancers. |
| 7413864 |
Treating cancer using a telomerase vaccine |
August 19, 2008 |
| The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for |
| 7388276 |
Metal-insulator varactor devices |
June 17, 2008 |
| A varactor is configured with first and second conducting layers, spaced apart from one another such that a given voltage can be applied across the first and second conducting layers. Further, an insulator arrangement includes at least one insulator layer disposed between the first and |
| 7374948 |
Methods and apparatus for detection of molecular chirality |
May 20, 2008 |
| The disclosure provides methods for the determination of the enantiomeric excess of chiral compounds. The methods involve doping a chiral analyte into an achiral liquid crystal host to form a chiral dopant/host liquid crystal mixture. An electro-optic signature of the mixture is then |
| 7341836 |
Modified cyclic nucleotide gated ion channels |
March 11, 2008 |
| The present invention provides modified cyclic nucleotide gated (CNG) channels. In particularly preferred embodiments, the modified CNG channels exhibit increased sensitivity and specificity for cAMP, as compared to wild-type CNG channels. In additional embodiments, regulation by Ca. |
| 7340938 |
MIS-based sensors with hydrogen selectivity |
March 11, 2008 |
| The invention provides hydrogen selective metal-insulator-semiconductor sensors which include a layer of hydrogen selective material. The hydrogen selective material can be polyimide layer having a thickness between 200 and 800 nm. Suitable polyimide materials include reaction produc |
| 7332111 |
Devices and methods for the production of particles |
February 19, 2008 |
| The present invention provides methods and devices for producing particles with an average diameter less than about 15 .mu.m using the precipitation with compressed fluid-antisolvent (PCA) process and the carbon-dioxide assisted nebulization with a bubble dryer (CAN-BD) process. In the |
| 7316727 |
High-selectivity supported SAPO membranes |
January 8, 2008 |
| SAPO membranes and methods for their preparation and use are described. The SAPO membranes are prepared by contacting at least one surface of a porous membrane support with an aged synthesis gel. A layer of SAPO crystals is formed on at least one surface of the support. SAPO crystals |
| 7315270 |
Differential delay-line analog-to-digital converter |
January 1, 2008 |
| Differential delay-line analog-to-digital (A/D) converters for use in current and power sensing applications are provided. These A/D converters are well suited for a wide range of electronic applications, including over-load protection, current mode control, current sharing in digitally |
| 7297488 |
Identifying and testing antisense oligonucleotides that inhibit telomerase reverse transcriptase |
November 20, 2007 |
| This disclosure provides TRT antisense oligonucleotides, methods of detecting TRT, methods of diagnosing telomerase-related conditions, methods of diagnosing and providing a prognosis for cancer, and methods of treating telomerase-related conditions, including cancer. |
| 7291699 |
Product and methods for diagnosis and therapy for cardiac and skeletal muscle disorders |
November 6, 2007 |
| Disclosed are products and methods to promote myoblast activation and cardiac and skeletal muscle growth or regeneration, and to treat heart and skeletal muscle diseases, based on the identification of cellular processes affected by prelamin A processing. |
| 7285639 |
Antibody to telomerase reverse transcriptase |
October 23, 2007 |
| The present invention is directed to monoclonal or recombinant antibodies or fragments thereof that bind to human telomerase reverse transcriptase (hTRT) protein. The present invention is also directed to methods of identifying or detecting hTRT polypeptides in biological samples. The |
| 7283716 |
Strain tunable, flexible photonic crystals |
October 16, 2007 |
| A device is described based on flexible photonic crystal, which is comprised of a periodic array of high index dielectric material embedded in a flexible polymer. Dynamic, real time tunability is achieved by the application of a variable force with a MEMS actuator or other means. The |
| 7262288 |
Nucleic acids encoding human telomerase reverse transcriptase and related homologs |
August 28, 2007 |
| The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for |
| 7242520 |
Method for optimizing output in ultrashort-pulse multipass laser amplifiers with selective use o |
July 10, 2007 |
| A method for optimizing multipass laser amplifier output utilizes a spectral filter in early passes but not in later passes. The pulses shift position slightly for each pass through the amplifier, and the filter is placed such that early passes intersect the filter while later passes |
| 7218448 |
Extended depth of field optical systems |
May 15, 2007 |
| A system for increasing the depth of field and decreasing the wavelength sensitivity of an incoherent optical system incorporates a special purpose optical mask into the incoherent system. The optical mask has been designed to cause the optical transfer function to remain essentially |
| 7212723 |
Monolithic waveguide arrays |
May 1, 2007 |
| A waveguide array is fabricated by providing a photoreactive material and generating an optical intensity pattern corresponding to a geometry of the waveguide array. A relative translation of the photoreactive material is effected through the optical intensity pattern. Thereafter, the |
| 7195911 |
Mammalian cells that have increased proliferative capacity |
March 27, 2007 |
| The present invention is directed to cells comprising a recombinant polynucleotide sequence that encodes a telomerase reverse transcriptase protein, variant, or fragment having telomerase catalytic activity when complexed with a telomerase RNA. |
| 7177515 |
Surface plasmon devices |
February 13, 2007 |
| A device including an input port configured to receive an input signal is described. The device also includes an output port and a structure, which structure includes a tunneling junction connected with the input port and the output port. The tunneling junction is configured in a way (i) |
| 7166463 |
Nucleic acids encoding modified olfactory cyclic nucleotide gated ion channels |
January 23, 2007 |
| The present invention provides modified cyclic nucleotide gated (CNG) channels. In particularly preferred embodiments, the modified CNG channels exhibit increased sensitivity and specificity for cAMP, as compared to wild-type CNG channels. In additional embodiments, regulation by Ca. |
| 7153514 |
Use of botulinum toxin therapy for prostatic hyperplasia and related disorders |
December 26, 2006 |
| The present invention relates to methods for treating neurological-urological conditions. This is accomplished by administration of at least one neurotoxin. |
| 7115849 |
Wavefront coding interference contrast imaging systems |
October 3, 2006 |
| Contrast Imaging apparatus and methods with Wavefront Coding aspheric optics and post processing increase depth of field and reduce misfocus effects in imaging Phase Objects. The general Interference Contrast imaging system is modified with a special purpose optical element and image |
| 7113623 |
Methods and systems for display and analysis of moving arterial tree structures |
September 26, 2006 |
| Methods and systems for reconstruction of a three-dimensional representation of a moving arterial tree structure from a pair of sequences of time varying two-dimensional images thereof and for analysis of the reconstructed representation. In one aspect of the invention, a pair of tim |
| 7106510 |
Wavefront coded imaging systems |
September 12, 2006 |
| The present invention provides improved Wavefront Coding imaging apparatus and methods composed of optics, a detector, and processing of the detected image. The optics are constructed and arranged to have the characteristic that the transverse ray intercept curves form substantially |
