| Patent Number |
Title Of Patent |
Date Issued |
| RE35212 |
Superconductor magnetic reading and writing heads |
April 16, 1996 |
| Read/write heads for exchanging information with a magnetic media in either vertical or horizontal recording modes include SQUID detectors coupled to the magnetic flux path of the head. Selective use of superconducting material improves the data interchange operating efficiency of the |
| 7436595 |
Extended depth of field optical systems |
October 14, 2008 |
| A system for increasing the depth of field and decreasing the wavelength sensitivity and the effects of misfocus-producing aberrations of the lens of an incoherent optical system incorporates a special purpose optical mask into the incoherent system. The optical mask has been designed to |
| 7429387 |
Use of botulinum toxin therapy for treatment of recalcitrant voiding dysfunction |
September 30, 2008 |
| The present invention related to methods for treating neurological-urological conditions. This is accomplished by administration of at least one neurotoxin. |
| 7427496 |
Anti-cancer compounds |
September 23, 2008 |
| The invention provides bradykinin antagonists and pharmaceutically acceptable salts thereof having anti-cancer activity. These anti-cancer compounds are particularly useful for inhibiting the growth of lung and prostate cancers. |
| 7413864 |
Treating cancer using a telomerase vaccine |
August 19, 2008 |
| The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for |
| 7388276 |
Metal-insulator varactor devices |
June 17, 2008 |
| A varactor is configured with first and second conducting layers, spaced apart from one another such that a given voltage can be applied across the first and second conducting layers. Further, an insulator arrangement includes at least one insulator layer disposed between the first and |
| 7374948 |
Methods and apparatus for detection of molecular chirality |
May 20, 2008 |
| The disclosure provides methods for the determination of the enantiomeric excess of chiral compounds. The methods involve doping a chiral analyte into an achiral liquid crystal host to form a chiral dopant/host liquid crystal mixture. An electro-optic signature of the mixture is then |
| 7341836 |
Modified cyclic nucleotide gated ion channels |
March 11, 2008 |
| The present invention provides modified cyclic nucleotide gated (CNG) channels. In particularly preferred embodiments, the modified CNG channels exhibit increased sensitivity and specificity for cAMP, as compared to wild-type CNG channels. In additional embodiments, regulation by Ca. |
| 7340938 |
MIS-based sensors with hydrogen selectivity |
March 11, 2008 |
| The invention provides hydrogen selective metal-insulator-semiconductor sensors which include a layer of hydrogen selective material. The hydrogen selective material can be polyimide layer having a thickness between 200 and 800 nm. Suitable polyimide materials include reaction produc |
| 7332111 |
Devices and methods for the production of particles |
February 19, 2008 |
| The present invention provides methods and devices for producing particles with an average diameter less than about 15 .mu.m using the precipitation with compressed fluid-antisolvent (PCA) process and the carbon-dioxide assisted nebulization with a bubble dryer (CAN-BD) process. In the |
| 7316727 |
High-selectivity supported SAPO membranes |
January 8, 2008 |
| SAPO membranes and methods for their preparation and use are described. The SAPO membranes are prepared by contacting at least one surface of a porous membrane support with an aged synthesis gel. A layer of SAPO crystals is formed on at least one surface of the support. SAPO crystals |
| 7315270 |
Differential delay-line analog-to-digital converter |
January 1, 2008 |
| Differential delay-line analog-to-digital (A/D) converters for use in current and power sensing applications are provided. These A/D converters are well suited for a wide range of electronic applications, including over-load protection, current mode control, current sharing in digitally |
| 7297488 |
Identifying and testing antisense oligonucleotides that inhibit telomerase reverse transcriptase |
November 20, 2007 |
| This disclosure provides TRT antisense oligonucleotides, methods of detecting TRT, methods of diagnosing telomerase-related conditions, methods of diagnosing and providing a prognosis for cancer, and methods of treating telomerase-related conditions, including cancer. |
| 7291699 |
Product and methods for diagnosis and therapy for cardiac and skeletal muscle disorders |
November 6, 2007 |
| Disclosed are products and methods to promote myoblast activation and cardiac and skeletal muscle growth or regeneration, and to treat heart and skeletal muscle diseases, based on the identification of cellular processes affected by prelamin A processing. |
| 7285639 |
Antibody to telomerase reverse transcriptase |
October 23, 2007 |
| The present invention is directed to monoclonal or recombinant antibodies or fragments thereof that bind to human telomerase reverse transcriptase (hTRT) protein. The present invention is also directed to methods of identifying or detecting hTRT polypeptides in biological samples. The |
| 7283716 |
Strain tunable, flexible photonic crystals |
October 16, 2007 |
| A device is described based on flexible photonic crystal, which is comprised of a periodic array of high index dielectric material embedded in a flexible polymer. Dynamic, real time tunability is achieved by the application of a variable force with a MEMS actuator or other means. The |
| 7262288 |
Nucleic acids encoding human telomerase reverse transcriptase and related homologs |
August 28, 2007 |
| The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for |
| 7242520 |
Method for optimizing output in ultrashort-pulse multipass laser amplifiers with selective use o |
July 10, 2007 |
| A method for optimizing multipass laser amplifier output utilizes a spectral filter in early passes but not in later passes. The pulses shift position slightly for each pass through the amplifier, and the filter is placed such that early passes intersect the filter while later passes |
| 7218448 |
Extended depth of field optical systems |
May 15, 2007 |
| A system for increasing the depth of field and decreasing the wavelength sensitivity of an incoherent optical system incorporates a special purpose optical mask into the incoherent system. The optical mask has been designed to cause the optical transfer function to remain essentially |
| 7212723 |
Monolithic waveguide arrays |
May 1, 2007 |
| A waveguide array is fabricated by providing a photoreactive material and generating an optical intensity pattern corresponding to a geometry of the waveguide array. A relative translation of the photoreactive material is effected through the optical intensity pattern. Thereafter, the |
| 7195911 |
Mammalian cells that have increased proliferative capacity |
March 27, 2007 |
| The present invention is directed to cells comprising a recombinant polynucleotide sequence that encodes a telomerase reverse transcriptase protein, variant, or fragment having telomerase catalytic activity when complexed with a telomerase RNA. |
| 7177515 |
Surface plasmon devices |
February 13, 2007 |
| A device including an input port configured to receive an input signal is described. The device also includes an output port and a structure, which structure includes a tunneling junction connected with the input port and the output port. The tunneling junction is configured in a way (i) |
| 7166463 |
Nucleic acids encoding modified olfactory cyclic nucleotide gated ion channels |
January 23, 2007 |
| The present invention provides modified cyclic nucleotide gated (CNG) channels. In particularly preferred embodiments, the modified CNG channels exhibit increased sensitivity and specificity for cAMP, as compared to wild-type CNG channels. In additional embodiments, regulation by Ca. |
| 7153514 |
Use of botulinum toxin therapy for prostatic hyperplasia and related disorders |
December 26, 2006 |
| The present invention relates to methods for treating neurological-urological conditions. This is accomplished by administration of at least one neurotoxin. |
| 7115849 |
Wavefront coding interference contrast imaging systems |
October 3, 2006 |
| Contrast Imaging apparatus and methods with Wavefront Coding aspheric optics and post processing increase depth of field and reduce misfocus effects in imaging Phase Objects. The general Interference Contrast imaging system is modified with a special purpose optical element and image |
| 7113623 |
Methods and systems for display and analysis of moving arterial tree structures |
September 26, 2006 |
| Methods and systems for reconstruction of a three-dimensional representation of a moving arterial tree structure from a pair of sequences of time varying two-dimensional images thereof and for analysis of the reconstructed representation. In one aspect of the invention, a pair of tim |
| 7106510 |
Wavefront coded imaging systems |
September 12, 2006 |
| The present invention provides improved Wavefront Coding imaging apparatus and methods composed of optics, a detector, and processing of the detected image. The optics are constructed and arranged to have the characteristic that the transverse ray intercept curves form substantially |
| 7105718 |
Compositions and methods for regulating metabolism in plants |
September 12, 2006 |
| The invention relates to methods and products for manipulating plant metabolism and resistance to infection. |
| 7083787 |
Yeast-dendritic cell vaccines and uses thereof |
August 1, 2006 |
| Disclosed is a vaccine that includes a dendritic cell loaded with a yeast vehicle and antigen. Also disclosed are methods of making the vaccine and using the vaccine to elicit cellular and humoral immune responses in a mammal. Additionally, a method to elicit an immune response by ad |
| 7072101 |
Downchirped pulse amplification |
July 4, 2006 |
| An ultrashort pulse amplifier produces high-power ultrafast laser pulses. Pulses first have net negative (i.e. blue to red) chirp applied, and are then amplified in a laser amplifier. After amplification, the pulses are compressed using propagation through a block of material or other |
| 7066988 |
Segmented plate for assembly within a confined area having limited access |
June 27, 2006 |
| A segmented plate adapted for assembly within a confined area or volume, and a method of assembly of the segmented plate. The plate, as assembled, has an exterior perimeter that includes exterior edge-boundaries of a plurality of generally rigid plate-sections, each of the plate-sections |
| 7064192 |
High pressure refolding of protein aggregates and inclusion bodies |
June 20, 2006 |
| The present disclosure provides an effective method for the refolding of denatured proteins in solution so that properly folded, biologically active protein in solution is recovered in high yield. The refolding takes place at pressures between about 0.25 kbar to about 3.5 kbar, advan |
| 7061292 |
Adaptive voltage regulator for powered digital devices |
June 13, 2006 |
| Apparatus for efficiently supplying energy to a device in a circuit, the apparatus comprising a powered device having a critical path delay; delay line operative to model said critical path delay; control logic responsive to output from said delay line and operative to generate contr |
| 7049066 |
Diagnosis and treatment of myocardial failure |
May 23, 2006 |
| The present invention provides methods of diagnosing myocardial failure in a human. The methods comprise obtaining a sample of myocardial tissue from a ventricle of the heart. In one embodiment, the expression of .alpha.-myosin heavy chain, .beta.-myosin heavy chain, or both, are qua |
| 7045293 |
Alteration of sequence of a target molecule |
May 16, 2006 |
| Method for splicing a target nucleic acid molecule with a separate nucleic acid molecule. Such splicing generally causes production of a chimeric protein with advantageous features over that protein naturally produced from the target nucleic acid prior to splicing. The method includes |
| 7010183 |
Surface plasmon devices |
March 7, 2006 |
| A device including an input port configured to receive an input signal is described. The device also includes an output port and a structure, which structure includes a tunneling junction connected with the input port and the output port. The tunneling junction is configured in a way (i) |
| 7005262 |
Methods for detecting nucleic acids encoding human telomerase reverse transcriptase |
February 28, 2006 |
| The present invention is directed to methods of identifying in a sample nucleic acids that encode human telomerase reverse transcriptase (hTRT) or its fragments. The present invention is also directed to oligonucleotide primers used in such methods. The invention is further directed |
| 7001602 |
Use of botulinum toxin therapy for urinary incontinence and related disorders |
February 21, 2006 |
| The present invention relates to methods for treating neurological-urological conditions. This is accomplished by administration of at least one neurotoxin. |
| 6982080 |
Hydroxyethyl starch--containing polypeptide compositions |
January 3, 2006 |
| The invention provides compositions containing hydroxyethyl starch and polypeptides, including therapeutic polypeptides such as interleukin-11, that provide for enhanced stability of the polypeptide following storage at room temperature or elevated temperatures. |
| 6967347 |
Terahertz interconnect system and applications |
November 22, 2005 |
| An assembly includes a first electrical circuitry for providing a first electrical signal containing data and a transmitting arrangement, connected with the first electrical circuitry, for receiving the first electrical signal and for converting the first electrical signal into an el |
| 6958721 |
Matched delay line voltage converter |
October 25, 2005 |
| A method and apparatus for measuring or converting voltage, the method comprising: applying an input voltage to a primary delay line; applying a reference voltage to a timer delay line; propagating a delay signal through the primary delay line; propagating a timer signal through the |
| 6940649 |
Wavefront coded imaging systems |
September 6, 2005 |
| The present invention provides improved Wavefront Coding imaging apparatus and methods composed of optics, a detector, and processing of the detected image. The optics are constructed and arranged to have the characteristic that the transverse ray intercept curves form substantially stra |
| 6913827 |
Nanocoated primary particles and method for their manufacture |
July 5, 2005 |
| Particles have an ultrathin, conformal coating are made using atomic layer deposition methods. The base particles include ceramic and metallic materials. The coatings can also be ceramic or metal materials that can be deposited in a binary reaction sequence. The coated particles are usef |
| 6897016 |
Alteration of sequence of a target molecule |
May 24, 2005 |
| Method for splicing a target nucleic acid molecule with a separate nucleic acid molecule. Such splicing generally causes production of a chimeric protein with advantageous features over that protein naturally produced from the target nucleic acid prior to splicing. The method includes |
| 6873733 |
Combined wavefront coding and amplitude contrast imaging systems |
March 29, 2005 |
| The present invention provides extended depth of field or focus to conventional Amplitude Contrast imaging systems. This is accomplished by including a Wavefront Coding mask in the system to apply phase variations to the wavefront transmitted by the Phase Object being imaged. The phase |
| 6864301 |
Preparation and use of photopolymerized microparticles |
March 8, 2005 |
| Methods of forming crosslinked polymer particles in situ from polymer precursors such as monomers or oligomers, comprising exposing a composition comprising at least one polymer precursor, a solvent or solvent mixture, and an antisolvent or antisolvent mixture to photoradiation under |
| 6858409 |
Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibi |
February 22, 2005 |
| Compounds are disclosed having the general formula R.sub.1 --X--R.sub.2, wherein R.sub.1 and R.sub.2 are biologically active groups, at least one of which is polypeptidic. X is a non-peptidic polymeric group. R.sub.1 and R.sub.2 may be the same or different. Preferred R.sub.1 and R.sub.2 |
| 6835949 |
Terahertz device integrated antenna for use in resonant and non-resonant modes and method |
December 28, 2004 |
| An assembly includes a device for receiving at least one input to produce an output. An antenna supports the device to transfer the input to the device and further to transfer the output from the device such that the antenna supports a selected one of the input and the output as a high |
| 6831935 |
Multistage synchronization of pulsed radiation sources |
December 14, 2004 |
| Accurate and efficient synchronization of two pulsed radiation sources (e.g. iwo mode locked lasers) is accomplished in stages. Rough synchronization is accomplished by synchronizing (for example) the fundamental repetition rate of the two lasers. Fine synchronization is accomplished |
| 6820011 |
Three-dimensional structure of complement receptor type 2 and uses thereof |
November 16, 2004 |
| Disclosed is a crystalline human CR2 protein in complex with C3d, and the three dimensional structure of the crystalline complex. Also disclosed are methods of use of the structure, particularly for structure-based identification of compounds that bind to CR2 and inhibit or enhance the |
