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The Curators of the University of Missouri Patents
Assignee:
The Curators of the University of Missouri
Address:
Columbia, MO
No. of patents:
332
Patents:


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Patent Number Title Of Patent Date Issued
7947345 Synthesis of poly(ethylene amine) on an oxide support May 24, 2011
Methods of polymerizing polyethylene-based polymers on a support, and supports coated with polyethylene-based polymers. The coated supports may be used to improve the ink fixation properties of an ink-jet printing medium. The coated supports may also be useful for highly tailored chr
7943805 Method of producing lower alcohols from glycerol May 17, 2011
A reactive-separation process converts glycerin into lower alcohols, having boiling points less than 200.degree. C., at high yields. Conversion of natural glycerin to propylene glycol through an acetol intermediate is achieved at temperatures from 150.degree. to 250.degree. C. at a p
7943390 Supported molecular biofluid viscosity sensors for in vitro and in vivo use May 17, 2011
A device and a method for measuring viscosity that includes attaching molecular rotors to a solid surface, exposing the solid surface to a fluid having a viscosity to be measured, and taking optical measurements to determine viscosity. The solid surface is preferably quartz, polystyr
7927437 Ordered nanoenergetic composites and synthesis method April 19, 2011
A structured, self-assembled nanoenergetic material is disclosed that includes a nanostructure comprising at least one of the group consisting of a fuel and an oxidizer and a plurality of substantially spherical nanoparticles comprising at least the other of the group consisting of a
7910553 Peptidyl prodrugs that resist P-glycoprotein mediated drug efflux March 22, 2011
A method of treating a patient for a condition wherein the bioactive agent of choice is DRUG, wherein DRUG is a substrate that is effluxed by the P-gp transporter, is provided, the method comprising administering to the patient an effective amount of a compound of formula (I): DRUG-X
7907809 Ultra-low refractive index high surface area nanoparticulate films and nanoparticles March 15, 2011
Nanoparticles having a mean particle size of less than about 25 nanometers and a mean pore size of less than 10 nanometers, and a mean surface area of at least 500 m.sup.2/g; nanoporous films of such nanoparticles; and composites and devices containing such nanoparticles and nanoporous
7903252 Noise cancellation in fourier transform spectrophotometry March 8, 2011
Increasing signal to noise ratio in optical spectra obtained by spectrophotometers. An interferometer introduces interference effects into a source light beam. A dual beam configuration splits the source beam having the interference effects into a reference beam and a sample beam. Th
7888005 Inhibitors of macromolecular activity February 15, 2011
The present invention relates generally to methods, kits, compositions, and combinations to identify anti-infective or anti-pathogenic agents. The present invention also relates to methods, kits, compositions, and combinations directed to identifying elements of RNA metabolism related
7880061 Soybean variety SN97-6946 February 1, 2011
A soybean variety designated SN97-6946, the plants and seeds of soybean variety SN97-6946, methods for producing a soybean plant produced by crossing the variety SN97-6946 with itself or with another soybean plant, and hybrid soybean seeds and plants produced by crossing the variety
7879721 Rapid heating with nanoenergetic materials February 1, 2011
The present process for rapidly heating and cooling a target material without damaging the substrate upon which it has been deposited. More specifically, target material is coated onto a first substrate. A self-propagating nanoenergetic material is selected that combusts at temperatu
7853437 Electromagnetic emissions stimulation and detection system December 14, 2010
A system and method for detecting and identifying electronic devices based on their unintended electromagnetic emissions ("UEE") signals is presented. During device classification, UEE signals are measured from a plurality of test devices and characteristic data is obtained from the
7825086 Acyclovir-peptide analogs November 2, 2010
Dipeptide and tripeptide ester derivatives of acyclovir and its analogs are disclosed which are useful to treat herpes virus infections. Also disclosed is a method for preparing a therapeutic agent for targeted delivery to ocular tissue comprising linking the therapeutic agent to one
7819997 Transparent composites and laminates and methods for making October 26, 2010
An exemplary method for making a transparent composite includes steps of combining a refractive index modifier with a precursor solution, combining glass with the precursor solution, and curing the precursor solution to create a transparent glass reinforced polymer composite. An exem
7816567 Method of producing lower alcohols from glycerol October 19, 2010
A reactive-separation process converts glycerin into lower alcohols, having boiling points less than 200.degree. C., at high yields. Conversion of natural glycerin to propylene glycol through an acetol intermediate is achieved at temperatures from 150.degree. to 250.degree. C. at a p
7811994 Phage display selection of anti fungal peptides October 12, 2010
A method for the identification of peptides having an affinity for the surface of fungi is provided as is a method for the identification of peptides capable of affecting the development of a fungus. Also provided are compositions containing peptides identified using the method of the
7809418 Optical device components October 5, 2010
Embodiments of the invention relate to an apparatus including a light source to generate a plurality of light beams with each of the plurality of light beams having a different wavelength range. The apparatus also includes a light funnel to direct the plurality of light beams to the
7786259 Attachment and elaboration strategies for inverse peptide synthesis August 31, 2010
The present invention provides a process for preparing an immobilized peptide derivative of formula (Vb): ##STR00001## comprising reacting a functionalized solid support comprising Sub-L wherein Sub is a solid support and L is a cleavable linker, with H--[NH--A--C(O)]--O(tBu), then
7776898 Opioid receptor active compounds August 17, 2010
The invention provides compounds of formula I: ##STR00001## wherein R.sup.1 to R.sup.4 and n have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutical compositions comprising a compound of formula I,
7763432 Compositions and methods for early pregnancy diagnosis July 27, 2010
Pregnancy-associated glycoproteins (PAGs) are structurally related to the pepsins, thought to be restricted to the hoofed (ungulate) mammals and characterized by being expressed specifically in the outer epithelial cell layer (chorion/trophectoderm) of the placenta. By cloning expressed
7760355 Focused droplet nebulizer for evaporative light scattering detector July 20, 2010
A focused droplet nebulizer of the invention produces substantially uniform droplets of a predetermined size. Droplets are pushed out through a small outlet orifice by the contraction of a chamber. The droplets can be carried on a substantially non-divergent path in a drift tube. A piezo
7759419 Corrosion resistant coatings July 20, 2010
A coating composition comprising an effective corrosion-inhibiting amount of a rare earth compound, a neutral to slightly acidic generating extender or an acidic generating extender, or combinations thereof is provided. In one embodiment, the corrosion-inhibiting components are combi
7752089 Adaptive inventory management system July 6, 2010
An adaptive inventory management system and method eliminates or minimizes frequency interference issues within a facility that employs a plurality of RFID readers for purposes of tracking and managing inventory. A middleware server activates and deactivates adjacent RFID readers within
7746266 Microwave and millimeter wave imaging system June 29, 2010
A sensor array having a plurality of modulated slots for microwave and/or millimeter wave imaging. The locations of the slots in the array define a spatial domain away from an object for detecting an electric field from the object. Each of the slots outputs a signal representative of the
7746084 Impedance measurement using line-to-line current injection June 29, 2010
An unbalanced line-to-line current is injected at an injected frequency in a three-phase ac circuit. A first set of voltages and currents are obtained. A first set of transformed voltages and transformed currents are produced. The circuit is injected with a second unbalanced line-to-
7744876 Methods and compositions for treatment, prevention, suppression, and/or delaying the onset of ty June 29, 2010
The present invention relates generally to methods and compositions for treatment, prevention, suppression, and/or delaying the onset of type 1 diabetes. More specifically, the present invention relates to the administration of a fusion protein comprising at least one immunoglobulin
7741058 Methods and compositions for detecting spermatozoa or semen in a sample June 22, 2010
The present invention concerns compositions and methods for evaluating fertility in humans and animals. The invention may also be used to identify reproductive cancers such as testicular cancer. In various embodiments of the invention, an Sptrx-3 enzyme is used as a fertility marker.
7732033 Sealants for structural member joints and methods of using same June 8, 2010
Thermoplastic sealants and methods for forming a joint, such as a weld joint, between one or more structural members using thermoplastic sealants are provided. The thermoplastic sealants have melting temperatures lower than the melting temperature of at least one of the structural me
7705084 Water borne film-forming compositions April 27, 2010
The present invention provides a film-forming composition comprising a particulate polymer or emulsified liquid pre-polymer, water and a coalescent aid comprising an ester having the formula RCOOX wherein R and X are independently hydrocarbyl or substituted hydrocarbyl, and at least
7700831 Method for inducing resistance to fungal infection in transgenic plants using plant defense pept April 20, 2010
The instant invention relates to a method of inducing resistance to pathogens including fungi in transgenic plants by introducing into the plants a first sequence encoding a plant defense peptide and a second sequence encoding a peptide delivery scaffold.
7696370 Soy based polyols April 13, 2010
The invention provides processes for converting a vegetable oil to a polymer. In particular, the processing steps comprise bodying, epoxidation, hydrolysis, and oligomerization. These processes provide new processing paths for the formation of polyols for use in rigid foam and other
7693369 Hollow core optical ring resonator sensor, sensing methods, and methods of fabrication April 6, 2010
The present invention is directed to hollow core optical ring resonators (HCORRs), methods of fabricating HCORRs, and methods of using HCORRs in sensing applications. In particular, the evanescent field and whispering gallery modes of the HCORRs may be used to detect a target analyte wit
7689016 Automatic detection of critical dermoscopy features for malignant melanoma diagnosis March 30, 2010
Improved methods for computer-aided analysis of identifying features of skin lesions from digital images of the lesions are provided. Improved preprocessing of the image that 1) eliminates artifacts that occlude or distort skin lesion features and 2) identifies groups of pixels within
7686452 Apparatus and method for assessing visual suppression March 30, 2010
A device is used to determine the presence of and the amount (depth) of visual suppression in a subject. The device includes a first light source emitting a first light and a second light source emitting a second light. Intensities of the light sources are independently controllable. A f
7670844 Supported molecular biofluid viscosity sensors for in vitro and in vivo use March 2, 2010
A device and a method for measuring viscosity that includes attaching molecular rotors to a solid surface, exposing the solid surface to a fluid having a viscosity to be measured, and taking optical measurements to determine viscosity. The solid surface is preferably quartz, polystyr
7666626 Mutants of the P4 protein of nontypable Haemophilus influenzae with reduced enzymatic activity February 23, 2010
A P4 variant protein that has reduced enzymatic activity and that induces antibody to wild-type P4 protein and/or has good bactericidal activity against non-typable H. influenzae (NTHi) is useful as an active component in an immunogenic composition for humans. Methods of using these
7663004 Method of producing lower alcohols from glycerol February 16, 2010
A reactive-separation process converts glycerin into lower alcohols, having boiling points less than 200.degree. C., at high yields. Conversion of natural glycerin to propylene glycol through an acetol intermediate is achieved at temperatures from 150.degree. to 250.degree. C. at a p
7651966 Alkaline resistant phosphate glasses and method of preparation and use thereof January 26, 2010
A substantially alkaline resistant calcium-iron-phosphate (CFP) glass and methods of making and using thereof. In one application, the CFP glass is drawn into a fiber and dispersed in cement to produce glass fiber reinforced concrete (GFRC) articles having the high compressive strength
7649359 Electrostatic thin film chemical and biological sensor January 19, 2010
A chemical and biological agent sensor includes an electrostatic thin film supported by a substrate. The film includes an electrostatic charged surface to attract predetermined biological and chemical agents of interest. A charge collector associated with said electrostatic thin film
7638284 Immunoglobulin A inducing protein and uses therefor December 29, 2009
The invention provides an isolated and purified nucleic acid molecule encoding mammalian immunoglobulin A inducing protein (IGIP), and methods of using the IGIP nucleic acid molecule and IGIP, e.g., to prepare antibodies. Also provided is an anti-IGIP antibody and uses therefor.
7618582 Continuous steel production and apparatus November 17, 2009
A process for continuous refining of steel via multiple distinct reaction vessels for melting, oxidation, reduction, and refining for delivery of steel continuously to, for example, a tundish of a continuous caster system, and associated apparatus.
7615229 Mutants of the P4 protein of nontypable Haemophilus influenzae with reduced enzymatic activity November 10, 2009
A P4 variant protein that has reduced enzymatic activity and that induces antibody to wild-type P4 protein and/or has good bactericidal activity against non-typable H. influenzae (NTHi) is useful as an active component in an immunogenic composition for humans. Methods of using these
7612256 Isolated nucleic acid molecules encoding the Br2 P-glycoprotein of maize and methods of modifyin November 3, 2009
The invention relates to the genetic modification of plants, particularly to the expression of P-glycoprotein genes in transformed plants. Nucleotide sequences for the Br2 gene encoding a P-glycoprotein of maize and methods for their use are provided. The sequences find use in modify
7611691 Compounds for treatment of copper overload November 3, 2009
The present invention provides compounds, pharmaceutical compositions, and methods that can be used to treat pathologies that are due to copper overload or to the presence of reactive oxygen species.
7608478 On-chip igniter and method of manufacture October 27, 2009
A chip for igniting nanoenergetic materials, includes a substrate, an igniter positioned on the substrate and the nanoenergetic material arranged in a linear pattern positioned on said substrate. A method of making a chip for igniting nanoenergetic materials includes providing a subs
7601886 Production of transgenic plants with increased seed yield October 13, 2009
The invention provides methods of producing plants with increased seed production and transgenic plants with increased seed yields produced by said methods.
7601425 Corrosion resistant coatings containing carbon October 13, 2009
A coating composition comprising an effective corrosion-inhibiting amount of a carbon pigment is provided. In one embodiment, the corrosion-inhibiting carbon pigment is further comprising other components such as extenders, including neutral to slightly acidic generating extenders an
7601126 Lameness evaluation systems and methods October 13, 2009
A wireless sensor-based lameness evaluation system detects and analyzes patterns of vertical head and pelvic motion of a four-legged animal in correlation with at least one limb movement. The system includes a plurality of motion sensors attached to the head, pelvis (or along the cen
7585509 Erb-2 receptor targeting peptide September 8, 2009
The ErbB-2 receptor, a member of the tyrosine kinase type 1 family of receptors, has been implicated in many human malignancies. Bacteriophage display technology was employed to identify peptides that bound to the extracellular domain of human ErbB-2. The peptide KCCYSL, most frequently
7575861 Compositions and method for accurate early pregnancy diagnosis August 18, 2009
The invention provides improved assays for detection of pregnancy. In the assays, pregnancy associated glycoproteins are analyzed in conjunction with progesterone analysis. The techniques of the invention overcome limitations in the prior art by reducing the rate of false positive re
7553812 Acyclovir-peptide analogs June 30, 2009
Dipeptide and tripeptide ester derivatives of acyclovir and its analogs are disclosed which are useful to treat herpes virus infections. Also disclosed is a method for preparing a therapeutic agent for targeted delivery to ocular tissue comprising linking the therapeutic agent to one
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