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The Center For Innovative Technology Patents
Assignee:
The Center For Innovative Technology
Address:
Herndon, VA
No. of patents:
55
Patents:


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Patent Number Title Of Patent Date Issued
5827888 Perinatal treatment of a fetus to avoid oxygen deprivation October 27, 1998
A method of using allosteric hemoglobin modifier compounds which promote the release of oxygen to improve delivery of oxygen from the mother to the fetus and the release of oxygen to tissues from fetal hemoglobin in treatment of maternal and fetal related syndromes.
5817160 UV absorbing glass October 6, 1998
UV absorbing glass is prepared by mixing ultrafine colloidal cerium oxide with glass-forming substances during the fabrication of the glass. An aqueous colloidal dispersion containing 1-20 weight percent 10-20 nm cerium oxide particles, optionally including a binder, is admixed with
5776490 Complex protein-walled microcapsules containing lipid-walled microcapsules and method for produc July 7, 1998
Complex protein walled microcapsules (40) incorporate lipid-walled microcapsules (48) that include constituents to be retained in the presence of hydration such as water soluble vitamins and minerals. The protein walled microcapsules (40) are cross-linked, and include constituents (4
5756482 Method of attenuation of nervous system damage May 26, 1998
A method is disclosed for attenuation of nervous system damage after injury which comprises administering therapeutic amounts of PREG, PREG-S, or esters of PREG or PREG-S together with an enhancer of secretory processes in non-neural cells such as a bacterial lipopolysaccharide and a
5705521 Use of allosteric hemoglobin modifiers in combination with radiation therapy to treat carcinogen January 6, 1998
A family of compounds has been found to be useful for right-shifting hemoglobin towards a low oxygen affinity state. The effect has particular application in radiation oncology applications. The compounds are capable of acting on hemoglobin in whole blood.
5690691 Gastro-intestinal pacemaker having phased multi-point stimulation November 25, 1997
A portable or implantable gastric pacemaker includes multiple electrodes that are positionable on the inner or outer surface of an organ in the gastro-intestinal tract and which are individually programmed to deliver a phased electrical stimulation to pace peristaltic movement of materia
5677330 Medical uses of allosteric hemoglobin modifier compounds in patient care October 14, 1997
A family of compounds has been found to be useful for right-shifting hemoglobin towards a low oxygen affinity state. The effect has particular application in a wide variety of treatments including hypoxia, hypothermia, ischemia, stroke, ARDS, COPD, surgical blood loss, acute nonvolem
5674677 Immunoassay technique using histidine tags, metals, and chelating agents October 7, 1997
Two amino acid sequences are joined together using an electron acceptor moiety and a linking moiety, such as a chelating agent. In particular, an amino acid sequence specific for binding to a material interest is linked to an enzyme which acts on an indicator, such as a colorimetric,
5651422 Universal-fit, quick-connect power drive/steer attachment for wheelchair July 29, 1997
A power drive/steer attachment for a wheelchair having a framework supporting a plurality of front and rear wheels and a seat for accommodating an operator, is adapted for use with a motive source and includes a frame for attachment to and detachment from the framework of the wheelch
5574022 Method of attenuating physical damage to the spinal cord November 12, 1996
A method is disclosed for attenuation of nervous system damage after injury which comprises administering therapeutic amounts of PREG, PREG-S, or esters of PREG or PREG-S together with an enhancer of secretory processes in non-neural cells such as a bacterial lipopolysaccharide and a
5547996 Method of producing foamed polymer materials August 20, 1996
Reacting carbonyls, such as aldehydes and ketones, with amines produces a ketimine or aldimine and a water byproduct. When the ketimine or aldimine reaction occurs in a polymer composition, the polymer becomes foamed due to the evolution of water. Hence, carbonyl and amine containing com
5547680 Method for preparing a topical, aminocaproic acid containing ophthalmic gel August 20, 1996
A topical gel formulation containing aminocaproic acid prevents secondary hemorrhage following hyphema without the adverse side effects associated with systemically delivered aminocaproic acid. Of ten human patients treated with the formulation, none have experienced a secondary hemorrha
5530111 Chemical modification of shaped hydrogels in non-aqueous medium June 25, 1996
A method is described for the chemical modification of pre-shaped hydrogels in non-aqueous medium. The conditions permit the reaction of highly expanded, porous hydrogel particles, such as spherical beads, using pseudo homogeneous reaction conditions in the absence of water. The method
5527667 Water sample viral contamination detection system June 18, 1996
Viral contamination in water samples is detected using a medium which includes both a substrate for .beta.-galactosidase and E. coli with elevated levels of intracellular .beta.-galactosidase. The substrate is chosen to undergo a detectable change (e.g., colorimetric, fluorometric, p
5523398 Cellulose derivatives with a low degree of substitution June 4, 1996
The invention is directed to the formation of cellulose derivatives using homogenous phase reaction conditions. Cellulose is dissolved using DMAc/LiCl and a reagent system is added to promote the acylation of an appropriate acid anhydride or free carboxylic acid. One reagent system i
5515444 Active control of aircraft engine inlet noise using compact sound sources and distributed error May 7, 1996
An active noise control system using a compact sound source is effective to reduce aircraft engine duct noise. The fan noise from a turbofan engine is controlled using an adaptive filtered-x LMS algorithm. Single multi channel control systems are used to control the fan blade passage
5508023 Pharmaceutically acceptable agents for solubilizing, wetting, emulsifying, or lubricating in met April 16, 1996
1,1,1,2,3,3,3-heptafluoropropane (HFC-227) has been identified as a highly polar propellant. Surfactants which have an elevated value (9.6 or greater) for their hydrophilic-lipophilic balance (HLB) can be used as suspending, wetting, and lubricating agents or cosolvents in metered dose
5508003 Metallic material with low melting temperature April 16, 1996
A gallium-indium-zinc-copper metallic material has been found to exhibit many of the advantageous properties of mercury, such as electrical conductivity, fluidity, and high vaporization temperature. The metallic material is formulated by combining individual components in the presence
5505954 Topical gel containing aminocaproic acid applied to the eye April 9, 1996
A topical gel formulation containing aminocaproic acid prevents secondary hemorrhage following hyphema without the adverse side effects associated with systemically delivered aminocaproic acid. Of ten human patients treated with the formulation, none have experienced a secondary hemorrha
5502041 Potent inhibitor of HIV reverse transcriptase March 26, 1996
An isolated, substantially pure, novel compound possessing HIV reverse transcriptase inhibitory activity, and method of preparing same are described.
5492689 Combined virustatic antimediator (COVAM) treatment of common colds February 20, 1996
The common cold and related disorders such as influenza, acute sinusitis, acute otitis, and infectious exacerbations of obstructive pulmonary disease, are best treated by providing a combination of antiviral agents and antiinflammatory compounds to a patient infected with a cold or i
5492688 Metered dose inhaler fomulations which include the ozone-friendly propellant HFC 134a and a phar February 20, 1996
Metered dose inhaler (MDI) formulations which utilize 1,1,1,2-tetrafluoroethane (HFC 134a) as the sole propellant are made practical by including a polar surfactant such as polyethylene glycol, diethylene glycol monoethyl ether, polyoxyethylene (20) sorbitan monolaurate, polyoxyethyl
5478978 Electrical switches and sensors which use a non-toxic liquid metal composition December 26, 1995
Liquid gallium or gallium alloy is utilized as the conductive fluid in a switch or sensor housing. In order to prevent wetting of the interior walls of the switch or sensor housing, the liquid gallium or gallium alloy is either free of metal oxides or has only very low quantities of meta
5466600 Use of carbon monoxide dehydrogenase for bioremediation of toxic compounds November 14, 1995
Toxic chlorinated compounds and nitro-aromatic compounds are rendered more environmentally friendly via a bioremediation process which employs carbon monoxide dehydrogenase, a microorganism containing carbon monoxide dehydrogenase, or a Co/Fe--S component of carbon monoxide dehydrogenase
5466600 Use of carbon monoxide dehydrogenase for bioremediation of toxic compounds November 14, 1995
Toxic chlorinated compounds and nitro-aromatic compounds are rendered more environmentally friendly via a bioremediation process which employs carbon monoxide dehydrogenase, a microorganism containing carbon monoxide dehydrogenase, or a Co/Fe--S component of carbon monoxide dehydrogenase
5458786 Method for dewatering fine coal October 17, 1995
Fine coals are dewatered in an energy efficient process in which a non-polar liquid or a mixture of different hydrophobic liquids are used to displace the water from the coal surface. This process works with higher rank coals that are naturally hydrophobic so that the coal surface from
5442540 Soft-switching PWM converters August 15, 1995
A full-bridge zero-voltage-switching pulse-width-modulated converter employs a saturable reactor in place of the linear inductor in order to reduce current stress on the active switches, reduce voltage stress on the rectifier diodes, and reduce secondary parasitic ringing. The zero-c
5442029 Methods of preparing polymeric ketones August 15, 1995
A new method for preparing commercially valuable polymeric ketones is described. The method employs an .alpha.-amiononitrile as a monomeric unit whereby an amorphous, soluble polymer having protected carbonyl moiety is obtained. Upon deprotecting the carbonyl moiety, a crystalline polyme
5432695 Zero-voltage-switched, three-phase PWM rectifier inverter circuit July 11, 1995
A novel switching rectifier circuit that combines the conventional three-phase, 6-stepped PWM rectifier/inverter circuit with a simple, low-power switch commutation circuit to provide zero-voltage turn-on for the switches, and soft turn-off for the diodes. The main features of the ne
5432191 Allosteric hemoglobin modifiers to decrease oxygen affinity in blood July 11, 1995
A family of compounds has been found to be useful for right-shifting hemoglobin towards a low oxygen affinity state. The compounds are capable of acting on hemoglobin in whole blood. In addition, the compounds can maintain the oxygen affinity in blood during storage and can restore the
5430142 Thermoplastic pentosan-rich polysaccharides from biomass July 4, 1995
A process for chemically modifying substantially pure xylose-rich oligosaccharides and polysaccharides in homogenous phase solution. The process may be advantageously utilized to produce biodegradable, thermoplastic, melt flowable, low shear resistant and low viscosity xylan derivati
5429818 Non-capsulated mutants of Actinobacillus pleuropneumoniae useful as vaccines July 4, 1995
Noncapsulated mutants of normally encapsulated bacteria in which the capsule is required for virulence are useful as vaccines for disease states caused by the normally encapsulated bacteria. In particular, a non-capsulated mutant of Actinobacillus (Haemophilus) pleuropneumoniae is us
5428039 Method for electively achieving reversible hyperpolarized cardiac arrest June 27, 1995
While performing cardiopulmonary bypass, the aorta is cross-clamped and the beating heart is stopped by introducing of an ATP-dependent potassium channel opening agent. The infusion into the coronary circulation shortens the cardiac action potential thereby arresting the heart muscle at
5422718 Elastic-part immersion cell for analyzing microstructures in materials June 6, 1995
The elastic-port immersion cell (10) is an optical oil immersion vessel which has a flexible latex (or other) sheath (24) protruding from its sidewall. The sheath is affixed to an opening in the wall of the vessel using a collar, O-ring (26) or other connecting means. The base of the
5415863 Topical containing aminocaproic acid for preventing secondary hemorrhage following hyphema May 16, 1995
A topical gel formulation containing aminocaproic acid prevents secondary hemorrhage following hyphema without the adverse side effects associated with systemically delivered aminocaproic acid. Of ten human patients treated with the formulation, none have experienced a secondary hemorrha
5407528 Oxygen plasma resistant polymeric film and fiber forming macromolecules containing the phosphine April 18, 1995
Poly(arylene ether phosphine oxide)s provide hydrolytic, thermal and oxidative stability. These materials have T.sub.g s ranging from about 190.degree.-280.degree. C., and are more self-extinguishing than other engineering thermoplastics tested when burned due to the presence of phos
5407479 Sol-gel .beta.-aluminum titanate thin film coating April 18, 1995
.beta.-Al.sub.2 TiO.sub.5 protective coatings have been developed for both dense and porous ceramics such as SiC and Si.sub.3 N.sub.4 using a chemical solution processing method involving the hydrolysis and condensation of aluminum tri-sec butoxide and titanium butoxide. The solution
5396260 Video instrumentation for the analysis of mineral content in ores and coal March 7, 1995
Mineral content in processed ore and coal content in coal slurries are determined using a video system. A video image is taken of a sample, the video image is digitized, and gray levels are assigned to points or areas on the video image. The distribution of the gray levels for the image
5391846 Alloy substitute for mercury in switch applications February 21, 1995
With proper handling, Gallium-Indium-Tin eutectics are suitable for use as a substitute for mercury in switch applications. The eutectics should be acid washed to prevent oxidation of the metal components of the eutectic while in the switch housing and, further, the switch housing should
5387629 Phosphorus containing poly(arylene ether)s useful as oxygen plasma resistant films and in nonlin February 7, 1995
Polymers containing the phosphine oxide moiety are identified as being particularly useful in applications where resistance to atomic oxygen etching is required and in applications where second order nonlinear optical effects will be utilized. Particularly preferred polymers for thes
5382680 Allosteric hemoglobin modifier compounds January 17, 1995
Allosteric hemoglobin modifier compounds having the general structural formula: ##STR1## wherein the R.sub.2, R.sub.3, R.sub.4, R.sub.5, and R.sub.6 moieties may be hydrogen, halogen or alkyl groups and may be the same or different, and wherein the R.sub.7 and R.sub.8 moieties ma
5357040 Fine powders of ketone-containing aromatic polymers and process of manufacture October 18, 1994
Fine particles of semi-crystalline ketone-containing aromatic polymers (PEEK, PEKK, etc.) are produced by controlling the rate and conditions of hydrolysis of an amorphous polyarylketimine intermediate. The choice of acid and its concentrations affects the rate of ketimine hydrolysis and
5355417 Active control of aircraft engine inlet noise using compact sound sources and distributed error October 11, 1994
An active noise control system using a compact sound source is effective to reduce aircraft engine duct noise. The fan noise from a turbofan engine is controlled using an adaptive filtered-x LMS algorithm. Single multi channel control systems are used to control the fan blade passage
5346830 Gene expression system based on regulatory elements of bateriophage P2 and satellite phage P4 September 13, 1994
An E. coli heterologous gene expression system comprising a multicopy expression vector comprising an F promoter from bacteriophage P2; and at least one copy of a DNA sequence comprising a delta gene from satellite P4 operably linked to a regulatable promoter on a different replicon is
5344914 Commercially valuable polymeric ketones and method of preparing same September 6, 1994
A new method for preparing commercially valuable polymeric ketones is described. The method employs an .alpha.-amiononitrile as a monomeric unit whereby an amorphous, soluble polymer having protected carbonyl moiety is obtained. Upon deprotecting the carbonyl moiety, a crystalline polyme
5339374 Fused biconical taper fiber optic coupler station and fabrication techniques August 16, 1994
The fibers are bound together about 1 cm apart. An oxy-propane torch is used to heat the fibers so that they fuse together. At the same time, the two relatively movable translational stages to which the fibers are clamped are pulled apart to form a biconical tapered region in the fibers.
5333622 Earplug and hearing devices formed in-situ August 2, 1994
A custom-molded earplug (18) for swimming protection, hearing protection, and the like, is fabricated in situ by depositing a foaming material (14 or 24) within a person's ear (10 or 42) and allowing the foaming material to form foam (16 or 44). Acoustic and electronic equipment such as
5328603 Lignocellulosic and cellulosic beads for use in affinity and immunoaffinity chromatography of hi July 12, 1994
Improved cellulosic beads for use as supports in bioaffinity chromatography are produced by dissolution of cellulose in a chaotropic cellulose solvent, formation of the dissolved cellulose into droplets, and immersion of the droplets into a non-solvent capable of solvent interchange with
5327225 Surface plasmon resonance sensor July 5, 1994
An optical fiber surface plasmon resonance (SPR) sensor includes both a metal layer and an overlay or underlay material on its surface. Existing fiber based SPR devices are inherently incapable of monitoring aqueous systems which have a refractive index ranging between 1.33 and 1.35, and
5305645 Dynamic measurement of material strength and life under cyclic loading April 26, 1994
A conventional dynamic testing machine, such as an MTS (Material Test System) is modified to allow for a new method for dynamically monitoring fatigue damage in a specimen. Load and stroke signals are used to determine phase angle and gain frequency response parameters for a specimen
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