| Patent Number |
Title Of Patent |
Date Issued |
| 7601800 |
Compositions and methods for monitoring breast cancer treatment |
October 13, 2009 |
| The present invention provides compositions and processes for preparing the same wherein the compositions are useful for monitoring breast cancer treatment. |
| 7553654 |
Non-toxic endophytes, plants injected therewith and methods for injecting plants |
June 30, 2009 |
| Isolated endophytes selected from the group consisting of ATCC Deposit No. PTA-6499, PTA-8827, PTA-8828, and PTA-8829 are disclosed. Seeds of plants stably infected with these endophytes are also disclosed. |
| 7537901 |
Extracellular serine protease |
May 26, 2009 |
| The present invention provides a DNA encoding a TADG-14 protein selected from the group consisting of: (a) isolated DNA which encodes a TADG-14 protein; (b) isolated DNA which hybridizes to isolated DNA of (a) above and which encodes a TADG-14 protein; and (c) isolated DNA differing from |
| 7531149 |
Synthetic control of metal oxide nanocrystal sizes and shapes |
May 12, 2009 |
| A general, reproducible, and simple synthetic method that employs readily available chemicals permits control of the size, shape, and size distribution of metal oxide nanocrystals. The synthesis entails reacting a metal fatty acid salt, the corresponding fatty acid, and a hydrocarbon |
| 7498411 |
P49/STRAP is a novel protein involved in gene regulation and cell proliferation |
March 3, 2009 |
| The invention provides isolated p49/STRAP protein, and isolated nucleic acids encoding a p49/STRAP protein. The inventors have discovered a new protein, named p49/STRAP that is expressed in cardiac tissue and other tissues in mammals. The p49/STRAP protein binds to serum response factor |
| 7476551 |
Diagnosing atherosclerosis risk by measuring carbamylated low density lipoprotein levels |
January 13, 2009 |
| The present invention provides a method of determining whether an individual is at risk for atherosclerosis, comprising the step of: measuring the level of carbamylated LDL in a sample obtained from said individual. Further provided is a method of reducing carbamylation in an individ |
| 7473873 |
Apparatus and methods for synthesis of large size batches of carbon nanostructures |
January 6, 2009 |
| An apparatus and method for synthesizing nanostructures. In one embodiment, the apparatus includes a reactor having a reaction zone and a conductive susceptor positioned in the reaction zone. The method includes the steps of transporting a gas mixture having an aerosolized catalyst, a |
| 7465855 |
Non-toxic endophytes, plants injected therewith and methods for injecting plants |
December 16, 2008 |
| A grass with improved environmental stress tolerance and low animal toxicity is disclosed where the grass is infected with an isolated endophyte selected from the groups consisting of USDA-PI no. 269850, Ijoukak, Morocco 92060, Boumalne-de-Dades, Morocco KBG 5921, USDA-PI no. 516560, |
| 7465537 |
Compounds and methods for inhibiting hepatitis C virus replication |
December 16, 2008 |
| The inventors have discovered that an ATPase-deficient dominant-negative mutant NS3 protein of hepatitis C virus inhibits activity of the wild-type NS3 protein and inhibits replication of hepatitis C virus (HCV). The solved crystal structure of a multi-enzyme NS3 complex on a DNA sub |
| 7371736 |
Gene expression profiling based identification of DKK1 as a potential therapeutic targets for co |
May 13, 2008 |
| Gene expression profiling reveals four distinct subgroups of multiple myeloma that have significant correlation with various clinical characteristics. Diagnosis for multiple myeloma (and possibly monoclonal gammopathy of undetermined significance) based on differential expression of |
| 7365658 |
Method and apparatus for lossless run-length data encoding |
April 29, 2008 |
| An apparatus and method for lossless run-length data encoding is disclosed. In the first stage of the method, an input data sequence is transformed without increasing its volume in order to obtain long sequences of identical digits. In the second stage, every such sequence is replace |
| 7341721 |
.beta..sub.2-microglobulin (.beta..sub.2m) and anti-.beta..sub.2m binding agents as anti-cancer |
March 11, 2008 |
| The present invention describes the use of agents that interact with major histocompatibility complex (MHC) HLA class I molecules, such as .beta..sub.2-microglobulin, or antibodies that bind to .beta..sub.2-microglobulin, for the treatment and prevention of multiple myeloma and other |
| 7309760 |
Repeat sequences of the CA125 gene and their use for diagnostic and therapeutic interventions |
December 18, 2007 |
| The CA125 gene has been cloned and multiple repeat sequences as well as the carboxy terminus have been identified. The CA125 molecule comprises three major domains: an extracellular amino terminal domain (Domain 1); a large multiple repeat domain (Domain 2); and a carboxy terminal domain |
| 7273904 |
Nanocrystals in ligand boxes exhibiting enhanced chemical, photochemical, and thermal stability, |
September 25, 2007 |
| Dendron ligands or other branched ligands with cross-linkable groups were coordinated to colloidal inorganic nanoparticles, including nanocrystals, and substantially globally cross-linked through different strategies, such as ring-closing metathesis (RCM), dendrimer-bridging methods, and |
| 7255332 |
System and method for dissolving gases in liquids |
August 14, 2007 |
| Apparatus and methods for dissolving a gas into a liquid comprises a saturation tank, a high pressure liquid pump in fluid communication with the tank, and a pressurized gas source in communication with a regulated gas head space of the saturation tank. The saturation tank comprises a |
| 7238496 |
Rapid and automated electrochemical method for detection of viable microbial pathogens |
July 3, 2007 |
| A method for in situ detection of viable pathogenic bacteria in a selective medium by measuring cathodic peak current of oxygen on cyclic voltammograms during bacterial proliferation with an electrochemical voltammetric analyzer. The rapid oxygen consumption at a time during the grow |
| 7217519 |
Histoplasma capsulatum chitin synthase sequences and their use for detection of Histoplasma caps |
May 15, 2007 |
| The present invention describes Histoplasmosis capsulatum chitin synthase nucleic acid and protein sequences as reagents for the detection of H. capsulatum infection. Specifically, the invention describes intron sequences from the H. capsulatum chitin synthase gene which can be used |
| 7211427 |
p49/STRAP is a novel protein involved in gene regulation and cell proliferation |
May 1, 2007 |
| The invention provides isolated p49/STRAP protein, and isolated nucleic acids encoding a p49/STRAP protein. The inventors have discovered a new protein, named p49/STRAP that is expressed in cardiac tissue and other tissues in mammals. The p49/STRAP protein binds to serum response factor |
| 7202143 |
Low temperature production of large-grain polycrystalline semiconductors |
April 10, 2007 |
| An oxide or nitride layer is provided on an amorphous semiconductor layer prior to performing metal-induced crystallization of the semiconductor layer. The oxide or nitride layer facilitates conversion of the amorphous material into large grain polycrystalline material. Hence, a native |
| 7174709 |
Turboscreen assembly for diesel exhaust systems |
February 13, 2007 |
| A turboscreen for use with diesel exhaust systems comprises a plurality of parallel metal V-shaped wires joined with a peripheral band. The turboscreen is reversibly provided within a housing assembly that permits removal of the interior screen without detaching the housing assembly |
| 7173179 |
Solar co-generator |
February 6, 2007 |
| A solar co-generator for producing both heat energy and electricity is disclosed. A solar concentrator directs sunlight into a container lined with solar cells and filled with a thermal transfer fluid. The fluid is transparent with respect to certain wavelengths of light that may be |
| 7160525 |
Monodisperse noble metal nanocrystals |
January 9, 2007 |
| Nanoparticle compositions of noble metals, and methods of making them, are described. The nanoparticle compositions are made by reacting a salt or complex of a noble metal, such as Au, Ag, Cu or Pt, with a weak ligand, and a reducing agent, in a single liquid phase. The noble metal is |
| 7112545 |
Passivation of material using ultra-fast pulsed laser |
September 26, 2006 |
| The surface of a semiconductor material, e.g., gallium arsenide, is passivated by irradiating the surface with ultra-short laser pulses, until a stable passive surface is achieved. The passive surface so prepared is devoid of a superficial oxide layer. |
| 7105051 |
High quality colloidal nanocrystals and methods of preparing the same in non-coordinating solven |
September 12, 2006 |
| The present invention provides substantially monodisperse colloidal nanocrystals and new preparative methods for the synthesis of substantially monodisperse colloidal nanocrystals. These synthetic methods afford the ability to tune nanocrystal size and size distribution. By using non |
| 7064188 |
Monoclonal antibodies which identify the glycoprotein carrying the CA125 epitope |
June 20, 2006 |
| Hybridomally produced monoclonal antibodies specifically immunoreactive with the glycoprotein carrying the CA 125 epitope. Monoclonal antibodies recognize both high and low molecular weight subunits of the antigen, and identify the antigen in the cytoplasm and the extracellular matrix of |
| 7052837 |
Histoplasma capsulatum catalase sequences and their use in the detection of Histoplamsa capsulat |
May 30, 2006 |
| The present invention describes Histoplasmosis capsulatum catalase A and catalase P nucleic acid and protein sequences as reagents for the detection of H. capsulatum infection. Specifically, the invention describes intron sequences from the H. capsulatum catalase A (CATA) and catalas |
| 7018834 |
Mutated herpes simplex virus type 1 thymidine kinases and uses thereof |
March 28, 2006 |
| The present invention provides new site-specific HSV-thymidine kinase mutants with improved nucleoside analog metabolizing activity due to low or no thymidine phosphorylation ability. Also provided is a method of killing target cells using such mutants combined with a prodrug. |
| 7014993 |
Extracellular serine protease |
March 21, 2006 |
| The present invention provides a DNA encoding a Tumor Antigen Derived Gene TADG-14 protein selected from the group consisting of: (a) isolated DNA which encodes a TADG-14 protein; (b) isolated DNA which hybridizes to isolated DNA of (a) above and which encodes a TADG-14 protein; and (c) |
| 7005722 |
RC terminator and production method therefor |
February 28, 2006 |
| A thin-film RC circuit element suitable for a transmission line termination circuit is prepared by a process wherein 1) a first metal layer of an anodizable metal is deposited on a substrate; 2) the exposed surface of the anodizable metal layer is anodized to produce an oxide layer |
| 6993377 |
Method for diagnosing heart disease, predicting sudden death, and analyzing treatment response u |
January 31, 2006 |
| A method of analyzing electrocardiogram (EKG) data for use in the diagnosis of heart disease, prognosis of cardiac conditions, and the monitoring of heart disease therapies is disclosed. The method utilizes a wavelet-based multifractal analysis with one or more of (1) a discrete wave |
| 6942978 |
Transmembrane serine protease overexpressed in ovarian carcinoma and uses thereof |
September 13, 2005 |
| The present invention provides a TADG-12 protein and a DNA fragment encoding such protein. Also provided is a vector/host cell capable of expressing the DNA. The present invention further provides various methods of early detection of associated ovarian and other malignancies, and of |
| 6872249 |
Synthesis of colloidal nanocrystals |
March 29, 2005 |
| A method of synthesizing colloidal nanocrystals is disclosed using metal oxides or metal salts as a precursor. The metal oxides or metal salts are combined with a ligand and then heated in combination with a coordinating solvent. Upon heating, the metal oxides or salts are converted to s |
| 6869545 |
Colloidal nanocrystals with high photoluminescence quantum yields and methods of preparing the s |
March 22, 2005 |
| The present invention provides new compositions containing colloidal nanocrystals with high photoluminescence quantum yields, new synthetic methods for the preparation of highly luminescent colloidal nanocrystals, as well as methods to control the photoluminescent properties of colloidal |
| 6806568 |
Decoupling capacitor for integrated circuit package and electrical components using the decoupli |
October 19, 2004 |
| A capacitive structure is made with thin film capacitor plates substantially surrounding an opening cavity for accommodating a chip. The capacitive structure includes at least one capacitor and is mounted around the periphery of a ball grid array (BGA) having a flip chip in the openi |
| 6787354 |
Methods for the early diagnosis of ovarian cancer |
September 7, 2004 |
| The disclosed nucleic acid primer sets, used in combination with quantitative amplification (PCR) of tissue cDNA, can indicate the presence of specific proteases in a tissue sample. Specifically, the present invention relates to expression of hepsin protease. The detected proteases a |
| 6669937 |
Monoclonal antibody antagonists for treating medical problems associated with d-amphetamine-like |
December 30, 2003 |
| The invention includes synthetic immunochemical haptens for the generation of antibodies, the antibodies, and the medical treatment applications for using the antibodies. The antibodies are designed to recognize the common molecular features of d-methamphetamine-like abused stimulants, a |
| 6664394 |
Derivatives of butyric acid |
December 16, 2003 |
| The present invention provides a series of compounds having structural formulas ##STR1##wherein n.sub.1 is 1 to 5, n.sub.2 is 1 to 4 and m is 1 to 3; X is O or NH; Y is CH2, O, S, NH, NR; R is selected from the group consisting a straight-chain aliphatic group, a branched-chain aliph |
| 6652260 |
Composite allograft press |
November 25, 2003 |
| A press to form a composite acetabular allograft cup for use in hip replacement surgery is disclosed. The acetabular cup formed by the press comprises bone cement and cancellous bone chips. The press includes a two-piece mold for forming the acetabular cup. The mold is removable from |
| 6649741 |
TADG-15: an extracellular serine protease overexpressed in carcinomas |
November 18, 2003 |
| The present invention provides DNA encoding a TADG-15 protein as well as a TADG-15 protein. Also provided is a vector capable of expressing the DNA of the present invention adapted for expression in a recombinant cell and regulatory elements necessary for expression of the DNA in the cel |
| 6627403 |
Methods for the early diagnosis of ovarian cancer |
September 30, 2003 |
| The disclosed nucleic acid primer sets, used in combination with quantitative amplification (PCR) of tissue cDNA, can indicate the presence of specific proteases in a tissue sample. The detected proteases are themselves specifically overexpressed in certain cancers, and their presenc |
| 6613653 |
Method of doping silicon, metal doped silicon, method of making solar cells, and solar cells |
September 2, 2003 |
| A low temperature process for forming a metal doped silicon layer in which a silicon layer is deposited onto a substrate at low temperatures, with a metal doping layer then deposited upon the silicon layer. This structure is then annealed at low temperatures to form a metal doped semicon |
| 6610289 |
Mutated herpes simplex virus type 1 thymidine kinases and uses thereof |
August 26, 2003 |
| The present invention provides new site-specific HSV-thymidine kinase mutants with improved nucleoside analog metabolizing activity due to low or no thymidine phosphorylation ability. Also provided is a method of killing target cells using such mutants combined with a prodrug. |
| 6602896 |
p38MAPK inhibitor and uses thereof |
August 5, 2003 |
| The present invention demonstrates that p38.sup.MAPK inhibitor induces low density lipoprotein receptor expression 6-8 fold, and further provides the application of such inhibitor in the treatment of hypercholesterolemia. |
| 6602674 |
Uses of antileukoprotease in carcinoma |
August 5, 2003 |
| The present invention provides a method of detecting/monitoring tumor growth and progression in a tissue by measuring the level of antileukoprotease. Also provided is a method of treating an individual having a tumor by administering antileukoprotease to inhibit the activity of strat |
| 6593462 |
Purified .beta.1,2-xylosyltransferase and uses thereof |
July 15, 2003 |
| The present invention provides a purified, homogeneous plant enzyme that adds a .beta.-1,2-linked xylose to the .beta.-linked mannose on the N-linked oligosaccharides of storage glycoproteins. This .beta.1,2-xylosyltransferase was purified from the microsomal fraction of soybean cell |
| 6551405 |
Tool and method for in situ vapor phase deposition source material reloading and maintenance |
April 22, 2003 |
| A tool and method for reloading source materials in a vapor phase deposition (VPD) environment is disclosed. The tool and method does not require the venting of the VPD environment in order to perform its functions. The tool may reload source material into effusion cells or electron |
| 6540976 |
Method for reducing radiation toxicity |
April 1, 2003 |
| Intestinal radiation injury (radiation enteropathy) is an important dose limiting factor during treatment of abdominal and pelvic tumors and a major determinant in the quality of life among cancer survivors. Inflammatory and fibrogenic mediators released by mucosal inflammatory cells |
| 6516504 |
Method of making capacitor with extremely wide band low impedance |
February 11, 2003 |
| A capacitor having a floating plate-shaped electrode, at least two patterned plate electrodes overlying the floating plate-shaped electrode, and a dielectric layer therebetween. The resulting structure exhibits high two-port insertion loss even at frequencies as high as 10 GHz. Notably, |
| 6504058 |
Fungicidal amides |
January 7, 2003 |
| Compounds of Formula I are disclosed which are useful as fungicides ##STR1##wherein R.sup.1 is hydrogen; halogen; C.sub.1 -C.sub.2 alkoxy; C.sub.1 -C.sub.2 haloalkoxy; cyano; or C.sub.1 -C.sub.2 alkyl optionally substituted with halogen, C.sub.1 -C.sub.2 alkoxy or cyano; R.sup.2 is |
| 6478769 |
Anatomical fluid evacuation apparatus and method |
November 12, 2002 |
| An apparatus and method for evacuating an anatomical fluid from a body cavity is disclosed. The disclosed apparatus and method is particularly useful in the performance of a pericardiocentesis procedure under emergency conditions. The apparatus consists of a needle and an integrated |
