| Patent Number |
Title Of Patent |
Date Issued |
| RE40014 |
Method for presenting high level interpretations of eye tracking data correlated to saved displa |
January 22, 2008 |
| A software program stores during a recording session eye-tracking data and all other communication device activities of a test person that self-controlled confronts her/himself with display scenarios or virtual pages. The display scenarios are stored simultaneously either: 1. after |
| RE38668 |
Method for inferring metal states from eye movements |
December 7, 2004 |
| A computer-implemented method infers mental states of a person from eye movements of the person. The method includes identifying elementary features of eye tracker data, such as fixations and saccades, and recognizing from the elementary features a plurality of eye-movement patterns. |
| RE35224 |
Histamine derivatives as immune modulators |
April 30, 1996 |
| Histamine derivatives are disclosed which find use as effect and tissue-specific immune modulators. Specifically, the primary terminal nitrogen in histamine is derivatized to introduce a variable length side chain having 0 to 1 branch of from 1 to 3 carbons; 0 to 2 non-oxo-carbonyl g |
| RE35102 |
Capillary electrophoretic device employing structure permitting electrical contact through ionic |
November 28, 1995 |
| A capillary tube has a structure in its wall that permits ions to flow but no substantial amount of electrolyte to move therethrough. The structure therefore permits electrical contact between the electrolyte inside the tube and the outside environment without diluting the electrolyte. T |
| 7620283 |
Optical device using a hollow-core photonic bandgap fiber |
November 17, 2009 |
| An optical device includes a hollow-core photonic-bandgap fiber, wherein at least a portion of the hollow-core photonic-bandgap fiber has a longitudinal axis and is twisted about the longitudinal axis. |
| 7619743 |
Optical sensor utilizing hollow-core photonic bandgap fiber with low phase thermal constant |
November 17, 2009 |
| An optical sensor includes a directional coupler comprising at least a first port, a second port, and a third port. The first port is in optical communication with the second port and with the third port such that a first optical signal received by the first port is split into a second |
| 7618654 |
Mammalian myeloid progenitor cell subsets |
November 17, 2009 |
| A substantially enriched mammalian hematopoietic cell subpopulation is provided, which is characterized by progenitor cell activity for myeloid lineages, but lacking the potential to differentiate into lymphoid lineages. This population is further divided into specific myeloid progen |
| 7616800 |
Polyp identification through subtraction of models of medical images |
November 10, 2009 |
| A method of identifying polyps and in a medical image is provided. In a first step, a 3-dimensional model is made of the medical image that contains both polyps (if any were present in the original medical image) and folds. Next, a second 3-dimensional model of the medical image, which |
| 7615834 |
Capacitive micromachined ultrasonic transducer(CMUT) with varying thickness membrane |
November 10, 2009 |
| Structure for capacitive micromachined ultrasonic transducer (CMUT) device or other vibrating membrane device having non-uniform membrane so that membrane mass and stiffness characteristics may be substantially independently adjusted. CMUT having trenched membrane and/or membrane wit |
| 7615382 |
Magnetic sifter |
November 10, 2009 |
| The present invention provides a magnetic sifter that is small in scale, enables three-dimensional flow in a direction normal to the substrate, allows relatively higher capture rates and higher flow rates, and provides a relatively easy method of releasing captured biomolecules. The |
| 7615368 |
Microarrays of polypeptides |
November 10, 2009 |
| Microarrays of polypeptides on a solid support are provided. The microarray compositions find use in the multiplexed detection and quantitation of ligands, e.g. antigens or antibodies, in a miniaturized format. The substrate is used for detecting binding of ligands to a plurality of |
| 7605150 |
Drug therapy for Celiac Sprue |
October 20, 2009 |
| Administering an effective dose of a tTGase inhibitor to a Celiac or dermatitis herpetiformis patient reduces the toxic effects of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten. |
| 7604981 |
Excitable target marker detection |
October 20, 2009 |
| A variety of types of molecules are detected and/or analyzed using an integrated micro-circuit arrangement. According to an example embodiment of the present invention, a micro-circuit arrangement detects excitable target markers in response to an excitation source. The excitation source |
| 7602183 |
K-T sparse: high frame-rate dynamic magnetic resonance imaging exploiting spatio-temporal sparsi |
October 13, 2009 |
| A method of dynamic resonance imaging is provided. A magnetic resonance imaging excitation is applied. Data in 2 or 3 spatial frequency dimensions, and time is acquired, where an acquisition order in at least one spatial frequency dimension and the time dimension are in a pseudo-rand |
| 7599593 |
Ge-Si quantum well structures |
October 6, 2009 |
| Si--Ge quantum wells where the well material has a lowest conduction band energy minimum at k=0 (the .GAMMA. point of the first Brillouin zone) are provided. Quantum well structures that satisfy this condition have "Kane-like" bands at and near k=0 which can provide physical effects |
| 7599074 |
Grating angle magnification enhanced angular sensor and scanner |
October 6, 2009 |
| An angular magnification effect of diffraction is exploited to provide improved sensing and scanning. This effect is most pronounced for a normal or near-normal incidence angle in combination with a grazing diffraction angle, so such configurations are preferred. Angular sensitivity |
| 7598275 |
Nicotine in therapeutic angiogenesis and vasculogenesis |
October 6, 2009 |
| Methods are provided for induction of angiogenesis by administration of nicotine or other nicotine receptor agonist. Induction of angiogenesis by the methods of the invention can be used in therapeutic angiogenesis in, for example, treatment of ischemic syndromes such as coronary or |
| 7598223 |
Methods for producing target cell reactive lymphocytes |
October 6, 2009 |
| Methods and compositions for producing target cell reactive lymphocytes, e.g., cytolytic T-lymphocytes, in a subject are provided. In practicing the subject methods, a lymphocyte population is contacted with an effective amount of a target cell peptide mixture of active and inactive |
| 7595883 |
Biological analysis arrangement and approach therefor |
September 29, 2009 |
| Characteristics of a chemical or biological sample are detected using an approach involving light detection. According to an example embodiment of the present invention, an assaying arrangement including a light detector is adapted to detect light from a sample, such as a biological mate |
| 7593426 |
Bit rate and power allocation for multi-carrier communication systems |
September 22, 2009 |
| Approaches to operating a multi-user, multi-carrier communication system involve allocating a target bit rate across user channels and subchannels to adjust the power. The target bit rate is allocated among subchannels of the user channels as a function of system power associated with th |
| 7592810 |
MRI methods for combining separate species and quantifying a species |
September 22, 2009 |
| A method for generating a magnetic resonance images is provided. A first species signal for a first species is generated from magnetic resonance data. A second signal is generated from the magnetic resonance data. The first species signal is combined with the second signal to provide a |
| 7592807 |
Maximum likelihood estimator in the presence of non-identically distributed noise for decomposit |
September 22, 2009 |
| A method of separating signals from at least two species in a body using echo-coherent time magnetic resonance imaging is provided. A plurality of echo signals is acquired at acquisition times optimized based on the noise properties of images with different variance with possibly cor |
| 7592806 |
Double half RF pulses for reduced sensitivity to eddy currents in UTE imaging |
September 22, 2009 |
| A method for creating a magnetic resonance image of an object with at least a first species and a second species, wherein the first species has a first T.sub.2 time and the second species has a second T.sub.2 time longer than the first T.sub.2 time is provided. An excitation with an |
| 7592174 |
Isolation of mesenchymal stem cells |
September 22, 2009 |
| Methods and compositions are provided for the identification and isolation of mammalian mesenchymal stem cells. The methods of the invention provide a means to obtain substantially homogeneous MSC populations. In some embodiments, the homogeneous MSC composition is stable in non-diff |
| 7592154 |
Modulating SOS response induction by antimicrobial agents |
September 22, 2009 |
| Compositions and methods are provided for the use of SOS pathway targeted agents in antimicrobial formulations. The innate sensitivity of bacteria to antibiotics is increased by disrupting a mechanism that normally activates the bacterial SOS response or by inhibiting steps in the SOS |
| 7590236 |
Identity-based-encryption system |
September 15, 2009 |
| Systems and methods for supporting symmetric-bilinear-map and asymmetric-bilinear-map identity-based-encryption (IBE) key exchange and encryption schemes are provided. IBE key exchange schemes use an IBE encapsulation engine to produce a secret key and an encapsulated version of the |
| 7585834 |
Transporters comprising spaced arginine moieties |
September 8, 2009 |
| The present invention provides compositions and methods for enhancing transport of biologically active compounds across biological membranes and across and into animal epithelial or endothelial tissues. The composition includes a biologically active agent and a transport moiety. The |
| 7582428 |
Methods and compositions for identifying anti-HCV agents |
September 1, 2009 |
| The invention provides methods and compositions for identifying agents for treating infection by viruses that encode a nucleotide-binding NS4B protein, or functional equivalent thereof, e.g., hepatitis C virus (HCV) or other members of the family Flaviviridae. In general, the methods |
| 7582417 |
Sequential reporter enzyme luminescence (SRL) methods and compositions for practicing the same |
September 1, 2009 |
| Sequential reporter enzyme luminescence (SRL) methods are provided. In the subject methods, the activity of a reporter enzyme is evaluated using a secondary reporter system that employs a product of a reporter enzyme mediated reaction as a luminescent substrate, e.g., luciferase substrat |
| 7580753 |
Method and system for stimulating a dorsal root ganglion |
August 25, 2009 |
| Some embodiments of the present invention provide a pulse generator for high impedance electrodes as well as stimulation systems and components for selective stimulation and/or neuromodulation of targeted neural tissue. Targeted neural tissue may include one or more dorsal root gangl |
| 7579328 |
DNA vaccination for treatment of multiple sclerosis and insulin-dependent diabetes mellitus |
August 25, 2009 |
| A pro-inflammatory T cell response is specifically suppressed by the injection into a recipient of DNA encoding an autoantigen associated with autoimmune disease. The recipient may be further treating by co-vaccination with a DNA encoding a Th2 cytokine, particularly encoding IL4. In |
| 7579313 |
Transglutaminase inhibitors and methods of use thereof |
August 25, 2009 |
| Transglutaminase inhibitors and methods of use thereof are provided. |
| 7576535 |
Multi-compartment separation in magnetic resonance using transient steady-state free precession |
August 18, 2009 |
| Disclosed is a method of quantitatively separating tissue signals based on relaxation time differences. The method uses the transient signal decay in steady-state free precession (balanced SSFP) imaging to provide an alternative to standard CPMG methods of T.sub.2-relaxometry. The balanc |
| 7563772 |
Methods of increasing cerebral blood flow |
July 21, 2009 |
| Methods of increasing blood flow in a mammalian brain blood vessel characterized by, or otherwise experiencing, decreased blood flow due to an ischemic or other hypoxic event, vasoconstriction or vasospasm following hemorrhagic stroke; due to chronic high blood pressure; and/or due t |
| 7563584 |
Methods and compositions for detecting the activation state of multiple proteins in single cells |
July 21, 2009 |
| The invention provides methods and compositions for simultaneously detecting the activation state of a plurality of proteins in single cells using flow cytometry. The invention further provides methods and compositions of screening for bioactive agents capable of coordinately modulat |
| 7563430 |
Inorganic metal chalcogen cluster precursors and methods for forming colloidal metal chalcogenid |
July 21, 2009 |
| Methods for forming colloidal metal chalcogenide nanoparticles generally include forming soluble inorganic metal chalcogen cluster precursors, which are then mixed with a surfactant and heated to form the colloidal metal chalcogenide nanoparticles. The soluble inorganic metal chalcogen |
| 7560925 |
Multiple repetition time steady-state free precession imaging |
July 14, 2009 |
| A method of providing selective spectral suppression in balanced SSFP magnetic resonance imaging for a first and second species is provided. A plurality of balanced SSFP images are acquired. Each acquisition includes applying RF excitations in a sequence of TR intervals with each being |
| 7560241 |
Methods and compositions for modulating mitochondrial aldehyde dehydrogenase-2 |
July 14, 2009 |
| The present invention provides screening methods for identifying agents that modulate the activity of mitochondrial aldehyde dehydrogenase-2 (AldDH2), as well as agents identified by the screening methods. The present invention further provides methods of reducing ischemic tissue dam |
| 7558612 |
Motion compensated spiral FISP MRI |
July 7, 2009 |
| Real-time imaging of a moving object such as the heart uses fast imaging with steady precession (FISP) traversing spirals in k-space. After flipping nuclear spins in the object within a slice to be imaged, signals are read out from the nuclear spins while applying read-out magnetic f |
| 7557051 |
3-D interconnected multi-layer microstructure of thermoplastic materials |
July 7, 2009 |
| Methods for compression molding through holes in polymer layers are provided, as are the resulting patterned polymer layers. Two key aspects of the invention are provision of a mold and substrate having different mechanical hardness, and provision of room for local flow of material. |
| 7556944 |
Methods and compositions for use in preparing siRNAs |
July 7, 2009 |
| Methods and compositions for producing siRNAs, e.g., in the form of a d-siRNA composition, from dsRNAs are provided. In the subject methods, a dsRNA is contacted with a composition that includes an activity that cleaves dsRNA into siRNAs, where the composition efficiently cleaves dsR |
| 7556922 |
Motion resolved molecular sequencing |
July 7, 2009 |
| Methods are provided for determining the sequence of a polynucleotide by tracking the motion of a nucleotide-selective, processive enzyme along a template, in a reaction mixture that alters the enzyme movement in a base specific manner. The movement trace of the enzyme is collected, and |
| 7556621 |
Optically controlled microfluidic chip |
July 7, 2009 |
| An optically controlled microfluidic chip is provided for administering a fluid to a neuronal site. The chip is made of at least one unit or pixel, each of which constitutively emits fluid in the dark, and reduces emission of fluid in response to light. The individual pixels are capable |
| 7553939 |
T cell regulatory genes and methods of use thereof |
June 30, 2009 |
| A genetic locus and corresponding family of proteins associated with regulation of immune function and cell survival are provided. These genes encode cell surface molecules with conserved IgV and mucin domains. The locus comprising the TIM family is genetically associated with immune |
| 7551819 |
Multiple-core photonic-bandgap fiber with coupling between the cores |
June 23, 2009 |
| An optical coupler includes a first optical port, a second optical port, a third optical port, and a fourth optical port. The optical coupler further includes a photonic-bandgap fiber having a cladding, a first core, and a second core. The cladding includes a material with a first re |
| 7549974 |
Device and method for medical interventions of body lumens |
June 23, 2009 |
| A directional balloon is provided that can be used for a medical intervention of a body lumen. In one aspect, the directional balloon inflates in a distal to proximal direction and deflates in a proximal to distal direction. In another aspect, the directional balloon inflates in a pr |
| 7548062 |
3D cones gradient waveform generation |
June 16, 2009 |
| A method of performing magnetic resonance imaging is provided. Sampling requirements are used to define a three dimensional cone trajectory differential equation. The equation is solved to obtain a starting point. A search is performed by performing a plurality of cycles, where each |
| 7545075 |
Capacitive micromachined ultrasonic transducer array with through-substrate electrical connectio |
June 9, 2009 |
| The embodiments of the present invention provide a CMUT array and method of fabricating the same. The CMUT array has CMUT elements individually or respectively addressable from a backside of a substrate on which the CMUT array is fabricated. In one embodiment, a CMUT array is formed on a |
| 7544669 |
Polynucleotide therapy |
June 9, 2009 |
| This invention provides a method of treating or preventing a disease in an animal associated with one or more self-protein(s), -polypeptide(s), or -peptide(s) that is present or involved in a non-physiologic process in the animal comprising administering to the animal a self-vector c |
| 7544654 |
.psi..epsilon.RACK peptide composition and method for protection against tissue damage due to is |
June 9, 2009 |
| A method of reducing damage to cells and tissue caused by an ischemic or hypoxic event is disclosed. The method includes administering to the cell or tissue, either in vivo or ex vivo, .psi..epsilon.RACK peptide. The peptide can be administered before, during or after the ischemic or |
