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Takara Bio Inc. Patents
Assignee:
Takara Bio Inc.
Address:
Shiga, JP
No. of patents:
55
Patents:


1 2


Patent Number Title Of Patent Date Issued
7622291 Agarase and gene thereof November 24, 2009
Production of efficiently producing agaro-oligosaccharide; a polypeptide having an agarase activity which is usable in, for example, efficiently extracting a substance such as a nucleic acid from an agarose gel; the amino acid sequence of the polypeptide; a gene encoding the polypeptide;
7612190 Method for targeting a polypeptide onto cellular surface November 3, 2009
The present invention relates to a polypeptide having an activity for targeting a heterogeneous polypeptide to a surface of cytoplasmic membrane, a nucleic acid encoding the polypeptide, a construct for introducing into a cell, comprising the nucleic acid, a transformant harboring a
7605000 Cold shock inducible expression and production of heterologous polypeptides October 20, 2009
The present invention relates to a DNA molecule or vector and a host cell containing this DNA molecule or vector which can be used to produce a heterologous polypeptide under conditions that elicit a cold shock response in the host cell. The DNA molecule and vector include a nucleoti
7604962 .alpha.-agarase and process for producing the same October 20, 2009
A polypeptide having an .alpha.-agarase activity, a gene encoding the polypeptide, a method for producing the polypeptide by genetic engineering and a method for producing an agarooligosaccharide using the polypeptide.
7572617 Thermostable ribonuclease H obtained from Archeoglobus profundus August 11, 2009
An isolated polypeptide having a thermostable ribonuclease H activity from Archaeoglobus profundus is highly useful in genetic engineering, as well as a gene encoding this polypeptide and a genetic engineering process for producing the polypeptide.
7553946 Promoters June 30, 2009
Isolated DNAs which are DNAs having a base sequence represented by any of SEQ ID NOS:1 to 6 in Sequence Listing or fragments thereof and showing a stationary phase-specific promoter activity in gram positive bacteria.
7521178 Method for synthesizing DNA April 21, 2009
A DNA synthesis reaction-enhancer comprising at least one kind selected from the group consisting of acidic substances and cationic complexes; a DNA synthesis method in which during a DNA synthesis reaction a reaction is carried out in the presence of the above enhancer by using DNA
7501262 Promoters and gene expression method by using the promoters March 10, 2009
To provide a promoter, a recombinant DNA, a gene expression vector, an expression vector, and a transformant, which are capable of expressing a gene without inducing gene expression with an inducer; and a method for producing a protein and a kit therefor, which can be operated easily and
7498357 Chalcone compounds March 3, 2009
The present invention provides a novel chalcone compound, its derivative or a salt thereof, each having a suppressive action of NO production or an inhibitory action of aldose reductase. In addition, the present invention provides a medicament, a food, a beverage or a feed having a t
7491511 Fungal antigens and process for producing the same February 17, 2009
There can be provided a fungal antigen which is an insoluble fraction obtainable from fungal cells of which cell wall has been substantially removed or at least partially removed; a process for producing the same; a nucleic acid encoding the fungal antigen; a biologic product containing
7491405 Antigenic protein originating in Malassezia February 17, 2009
A substantially pure, isolated, antigenic protein from fungi of the genus Malassezia, characterized in that said antigenic protein has a binding ability to IgE antibodies from patients with allergoses; an antigenic fragment derived from the antigenic protein; and an antibody against the
7485448 Serum-free medium for producing retroviruses February 3, 2009
A method for obtaining a virus vector free of a serum, and a serum-free medium for cultivation of a virus producer cell which can be used for the method are provided. By cultivating a virus producer cell using a serum-free medium containing serum albumin, it is possible to cultivate
7449568 Alga-origin promoter, intron and terminator November 11, 2008
A promoter, an intron and a terminator by which a useful foreign gene can be efficiently expressed in algae and which are thus useful in breeding algae using genetic engineering techniques.
7449553 Antibody that binds ceramidase November 11, 2008
A neutral/alkaline ceramidase derived from a mammal; an antibody specifically binding thereto; a probe and primer which are capable of specifically hybridizing thereto; a method for producing the ceramidase by a genetic engineering means; a method for detecting the ceramidase or the
7442683 Cyclic peptide October 28, 2008
A novel cyclic peptide having an antifungal activity, its pharmacologically acceptable salts and antifungal medicinal compositions containing the same.
7422888 Thermotolerant ribonuclease H September 9, 2008
Polypeptides having an RNase H activity highly useful in genetic engineering; genes encoding these polypeptides; and a process for genetic engineeringly producing these polypeptides.
7422750 Food or beverage containing fucoidan and method of production thereof September 9, 2008
Food or beverage where fucoidan which is derived from a fucoidan-containing substance is contained therein, added thereto and/or diluted therein. Food or beverage where fucoidan which is derived from a fucoidan-containing substance and where algins are reduced or eliminated, is conta
7417031 Use of algae-derived physiologically active substances for treating a carcinomatous disease August 26, 2008
Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): ##STR00001## foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting
7410953 Anticancer agent August 12, 2008
The present invention is to offer a pharmaceutical agent which is capable of suppressing the growth of cancer in cancer cells and the surrounding tissues thereof or in tissue of non-diseased part. An anticancer agent having a mannan-binding protein or gene thereof as an effective com
7410786 Sulfated fucogalactan digesting enzyme gene August 12, 2008
A gene encoding a polypeptide having an activity of digesting sulfated fucogalactan which is useful in sugar chain engineering reagents, analyzing the structures of sulfated fucose-containing polysaccharides and preparing degraded products of the polysaccharides; a genetic engineerin
7364787 Sphingolipid ceramide N-deacylase, methods for producing sphingolipids and sphingolipid derivati April 29, 2008
The present invention relates to a novel sphingolipid ceramide N-deacylase (SCDase) having a wide substrate specificity; a method for enzymatically producing a lysosphingolipid or a sphingolipid derivative using the SCDase which is useful in the fields of medicine, carbohydrate engin
7361774 Chalcone compound April 22, 2008
The present invention relates to a chalcone compound represented by the following general formula: ##STR00001## wherein R.sub.1 and R.sub.2 are taken together with the carbon atom to which they are bound, respectively, to form a hydroxydimethyl hexane ring, or where R.sub.1 is a hyd
7351556 .alpha.-agarase and process for producing the same April 1, 2008
A polypeptide having an .alpha.-agarase activity, a gene encoding the polypeptide, a method for producing the polypeptide by genetic engineering and a method for producing an agarooligosaccharide using the polypeptide.
7329524 Agarase and gene thereof February 12, 2008
Production of efficiently producing agaro-oligosaccharide; a polypeptide having an agarase activity which is usable in, for example, efficiently extracting a substance such as a nucleic acid from an agarose gel; the amino acid sequence of the polypeptide; a gene encoding the polypeptide;
7326530 Method for localizing polypeptide on cell surface February 5, 2008
The present invention relates to a polypeptide having an activity for targeting a heterogeneous polypeptide to a surface of cytoplasmic membrane, a nucleic acid encoding the polypeptide, a construct for introducing into a cell, comprising the nucleic acid, a transformant harboring a
7314744 Hyperthermostable protease gene January 1, 2008
There are provided hyperthermostable proteases having an amino acid sequences represented by SEQ ID Nos. 1, 3 and 5 of the Sequence Listing or functional equivalents thereof and hyperthermostable protease genes encoding those hyperthermostable protease. There is also disclosed a proc
7268160 Remedies September 11, 2007
The present invention provides a therapeutic agent or prophylactic agent for a disease that requires enhancement of nerve growth factor production, an enhancer for nerve growth factor production, or a food, beverage or feed for enhancing nerve growth factor production, each comprisin
7244588 Cold-induced expression vector July 17, 2007
A vector having a region encoding a cold shock protein gene mRNA-origin 5'-nontranslated region, characterized in that the 5'-nontranslated region has a mutation having been transferred therein so as to change the distance of the stem structure formed by the region.
7217817 Agarobiose-containing composition May 15, 2007
A material containing agarobiose; a method for preparing the material; and a food, a drink or a seasoning using the material, which is tasty and has the effect of alleviating a stimulant taste and of enhancing the depth of sweetness.
7217552 Sulfated fucogalactan digesting enzyme gene May 15, 2007
A gene encoding a polypeptide having an activity of digesting sulfated fucogalactan which is useful in sugar chain engineering reagents, analyzing the structures of sulfated fucose-containing polysaccharides and preparing degraded products of the polysaccharides; a genetic engineerin
7183077 Promoters and gene expression method by using the promoters February 27, 2007
To provide a promoter, a recombinant DNA, a gene expression vector, an expression vector, and a transformant, which are capable of expressing a gene without inducing gene expression with an inducer; and a method for producing a protein and a kit therefor, which can be operated easily and
7144719 Method for producing protease December 5, 2006
A hyperthermostable protease having the amino acid sequence represented by the SEQ ID NO:1 of the Sequence Listing or a sequence derived therefrom by deletion, substitution, insertion or addition of one to several amino acid residues, a gene encoding the hyperthermostable protease, and a
7141402 .alpha.-Agarase and process for producing the same November 28, 2006
A polypeptide having an .alpha.-agarase activity, a gene encoding the polypeptide, a method for producing the polypeptide by genetic engineering and a method for producing an agarooligosaccharide using the polypeptide.
7135291 Method of detecting nucleotide polymorphism November 14, 2006
A Nucleotide useful for detecting a base substitution in a gene, a method for detecting a base substitution in a gene using said Nucleotide, and a kit for the same.
7125984 Glucuronofucan sulfate October 24, 2006
Three enzymes degrading sulfated glucuronofucan; processes for producing these enzymes; activators for these enzymes; glucuronofucan sulfate and degradation products thereof; and a novel microorganism.
7125690 Promoters showing stationary phase-specific activity in gram-positive bacteria October 24, 2006
Isolated DNAs which are DNAs having a base sequence represented by any of SEQ ID NOS: 1 to 6 in Sequence Listing or fragments thereof and showing a stationary phase-specific promoter activity in Gram-positive bacteria.
7101699 Sphingolipid ceramide deacylase gene September 5, 2006
A polypeptide possessing a sphingolipid ceramide deacylase activity; a nucleic acid encoding the polypeptide; a recombinant DNA comprising the nucleic acid; a carrier for introducing into a cell, carrying the nucleic acid or the recombinant DNA; a transformant harboring the nucleic acid
7078386 Enhancing agent for nerve growth factor production comprising a compound having a coumarin backb July 18, 2006
The present invention relates to a medicament, a food, a beverage or a feed, each comprising as an effective ingredient a compound having an enhancing action for NGF production, which is effective for a treatment, an amelioration of symptom, prevention or the like of a disease requiring
7070931 Cancer control July 4, 2006
Clarification of the relationship between the functions of E1AF gene and the invasion and metastasis of cancers, and application thereof to cancer control, more specifically the control of cancer cell invasion by controlling the expression of E1AF gene and the products of expression,
7070793 Antigen protein and nucleic acid coding for said protein July 4, 2006
To provide a novel antigenic protein and a nucleic acid encoding the antigenic protein, which are useful for prophylaxis, treatment and diagnosis of diseases caused by fungi including Candida albicans. An antigenic protein characterized in that the antigenic protein is recognized by
7056671 Isothermal chimeric primer nucleic acid amplification methods using blocking oglionucleotide June 6, 2006
Methods of amplifying a target nucleic acid whereby the target nucleic acid is amplified in the presence of a deoxyribonucleotide triphosphate, a DNA polymerase having strand displacement activity, at least one chimeric oligonucleotide primer, at least one upstream block oligonucleot
7041656 Sulfated fucoglucuronomannan May 9, 2006
An enzyme which decomposes a sulfated fucoglucuronomannan and is useful in the field of glycotechnology; a process for producing the enzyme; a fucoidan fraction reduced in the number of the kinds of molecules and useful as a reagent in glycotechnology; a sulfated fucoglucuronomannan
7041452 Method of detecting the presence of absence of mixed varieties in grains, and identifying the mi May 9, 2006
Provided is a DNA-level grain variety discrimination method of detecting the presence or absence of any other varieties of grains in object grains of a certain variety through multiplex PCR that uses the DNAs extracted from the grains or from their processed products as templates. The me
6995010 Gene transfer method February 7, 2006
A method of transferring a foreign gene into cells, characterized by involving: the step of transferring into the cells with the use of an adenovirus vector, a first nucleic acid, which has a sequence provided with adeno-associated virus-origin ITRs in both sides of the target foreig
6951722 Method for amplifying nucleic acid sequence October 4, 2005
A convenient and effective method for amplifying a nucleic acid sequence characterized by effecting a DNA synthesis reaction in the presence of chimeric oligonucleotide primers; a method for supplying a large amount of DNA amplification fragments; an effective method for amplifying a nuc
6927289 Sulfated fucan oligosaccharide August 9, 2005
A smaller molecule obtainable by allowing a sulfated fucan-digesting enzyme which digests a novel sulfated polysaccharide derived from an alga belonging to Laminariales to act on a sulfated fucan, and a method for producing the same.
6921656 Polypeptides having glucoamylase activity July 26, 2005
Polypeptides having the amino acid sequence represented by SEQ ID NO:6 in Sequence Listing or an amino acid sequence derived from the above sequence by at least one of deletion, addition, insertion or substitution of one or more amino acids and showing a thermophilic glucoamylase activit
6916920 Process for producing hydrazinomonosaccharide derivatives and use thereof July 12, 2005
A process for producing hydrazinomonosaccharide derivatives and use of hydrazines in determining the structures of aldose and ketose monosaccharides located at the reducing ends of saccharides.
6911208 Antigenic protein originating in malassezia June 28, 2005
A substantially pure, isolated, antigenic protein from fungi of the genus Malassezia, characterized in that said antigenic protein has a binding ability to IgE antibodies from patients with allergies; an antigenic fragment derived from the antigenic protein; and an antibody against the
6897042 Low-temperature inducible expression vector May 24, 2005
A vector which is characterized in containing each of the following elements: (1) a promoter which shows its action in the host to be used; (2) regulatory region for regulating the action of the promoter of (1); and (3) a region which codes for the 5'-untranslated region derived from
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