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Syntex Patents
Assignee:
Syntex
Address:
U.S.A.) Inc. (Palo Alto, CA
No. of patents:
938
Patents:


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Patent Number Title Of Patent Date Issued
RE31965 Compliantly mountable turbine cartridge assembly for gas-driven dental handpiece August 6, 1985
A single-unit turbine cartridge assembly for a gas-driven dental handpiece includes a pair of bearing assemblies mounted on a turbine rotor shaft and a ring of resilient material around each bearing assembly. The resilient ring provides radial support for the turbine cartridge assembly w
RE31406 Oxygen permeable contact lens composition, methods and article of manufacture October 4, 1983
Contact lenses are fabricated from a copolymer of a polysiloxanylalkyl acrylic ester and an alkyl acrylic ester. The copolymer has increased oxygen permeability.
RE28819 Dialkylated glycol compositions and medicament preparations containing same May 18, 1976
A pharmaceutical preparation having a minor amount of a medicament, a major amount of a dialkylated mono- or poly-alkylene glycol vehicle therefor, and a minor amount of one or more antioxidants for the dialkylated glycol vehicle.
D294807 Cassette for chromatograph March 22, 1988
D291185 Chromatography cassette August 4, 1987
D286481 Cabinet door or similar article November 4, 1986
D286177 Cabinet door October 14, 1986
D285395 Drawer front or similar article September 2, 1986
D282992 Combined cup and towel dispenser March 18, 1986
D282683 Operatory module system for a health treatment facility February 18, 1986
D282682 Operatory module for a health treatment facility February 18, 1986
D282681 Operatory module for a health treatment facility February 18, 1986
D282575 Operatory module for a health treatment facility February 11, 1986
D282574 Operatory module for a health treatment facility February 11, 1986
D282573 Operatory module for a health treatment facility February 11, 1986
D282572 Operatory module for a health treatment facility February 11, 1986
D282571 Operatory module for a health treatment facility February 11, 1986
D281656 Seating unit for a patient's chair December 10, 1985
D280517 Transparency viewer September 10, 1985
D268149 Dental chair March 8, 1983
D266109 Dental scaler September 7, 1982
D261301 Dental handpiece October 13, 1981
D261032 Dental handpiece September 29, 1981
D260703 Dental chair September 15, 1981
D259362 Dental bur wrench tool May 26, 1981
D248101 Electronic control and display console June 6, 1978
D246111 Axial tomographic scanner housing October 18, 1977
7186841 Antiinflammation agents March 6, 2007
Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic and cell proliferative conditions or diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of protei
7141365 Methods for diagnosing a mucin production associated disease condition November 28, 2006
Methods and compositions for modulating mucin secretion by respiratory system cells are provided. In the subject methods, an effective amount of an hCLCA2 (or homolog thereof) modulatory agent is contacted with the cell to modulate mucin secretion, e.g., decrease or increase mucin se
7122325 Method of modulating tetrotodoxin-resistant sodium channel October 17, 2006
The present invention relates to a voltage-gated sodium channel present in peripheral nerve tissue that is tetrodotoxin-resistant. One aspect of the present invention is purified and isolated DNA encoding this sodium channel. Another aspect of the present invention is the recombinant
7094778 Heterocyclylalkylamines as muscarinic receptor antagonists August 22, 2006
This invention relates to compounds which are generally muscarinic M2/M3 receptor antagonists and which are represented by Formula I: ##STR00001## wherein X, Y, and Z are O, S or NR.sup.5, and the other substituents are as defined in the specification; and prodrugs, individual isomers,
7094591 Human aggrecanase and nucleic acid compositions encoding the same August 22, 2006
Human aggrecanase and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening appl
7074763 Stable formulations of nerve growth factor July 11, 2006
Aqueous formulations of nerve growth factor suitable for lyophilization and subsequent reconstitution in which nerve growth factor is admixed with sugars and buffer are provided.
7071177 P-(sulfonyl) aryl and heteroarylamines as anti-inflammatory agents July 4, 2006
This invention relates to anti-inflammatory and analgesic compounds, especially to certain p-(sulfonyl)phenyl amino derivatives, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.
7070971 Glycosyl sulfotransferases GST-4.alpha., GST-4.beta., and GST-6 July 4, 2006
Novel glycosylsulfotransferases (GST-4.alpha., GST-4.beta., and GST-6) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including vario
7056903 Carboxylic acid derivatives as IP antagonists June 6, 2006
This invention relates to compounds which are generally IP receptor antagonists and which are represented by Formula I: ##STR00001## wherein: R.sup.1, R.sup.2, and R.sup.3 are each independently in each occurrence aryl or heteroaryl; R.sup.4 is --COOH or tetrazolyl; A, B, m, n, and
7053103 Ring fused pyrazole derivatives as CRF antagonists May 30, 2006
This invention relates to compounds which are generally CRF-1 receptor antagonists and which are represented by Formula I or Formula II: ##STR00001## wherein Ar is optionally substituted aryl or heteroaryl, R.sup.1 R.sup.4 are as defined in the specification; or individual isomers,
7049325 Quinoline derivatives as anti-inflammatory agents May 23, 2006
This invention relates to compounds, which are generally anti-inflammatory and analgesic compounds, and which are represented by Formula I: ##STR00001## wherein A is a CH.sub.2, CH(OH), C(O), C.dbd.NOR.sup.4, NR.sup.5, O, S, S(O), or S(O).sub.2, and the other substituents are as def
7049317 CCR-3 receptor antagonists May 23, 2006
The invention provides compounds of Formula (I): ##STR00001## wherein R.sub.1 R.sub.4 have any of the values defined in the specification that are CCR-3 receptor antagonists, pharmaceutical compositions containing them, methods for their use, and methods and intermediates useful for
7019007 CCR-3 receptor antagonists (I) March 28, 2006
The invention provides compounds of Formula (I): ##STR00001## wherein: R.sup.1 R.sup.4, A, D, and L have any of the values defined in the specification that are CCR-3 receptor antagonists, pharmaceutical compositions containing them, methods for their use, and methods and intermedi
6984637 Cyclic amine derivatives-CCR-3 receptor antagonists January 10, 2006
This invention relates to certain cyclic amine derivatives of Formula (I) ##STR00001## that are CCR-3 receptor antagonists, pharmaceutical compositions containing them, methods for their use and methods for preparing these compounds.
6979693 Pyrazole derivatives-p38 MAP kinase inhibitors December 27, 2005
The present invention relates to certain pyrazole derivatives of Formula (I): ##STR1##that are p-38 MAP kinase inhibitors, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.
6967093 Glycosyl sulfotransferase-3 November 22, 2005
A novel human glycosylsulfotransferase expressed in high endothelial cells (GST-3) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, includi
6951918 Peptidic procollagen C-proteinase inhibitors October 4, 2005
This invention relates to compounds of Formula (I) ##STR1##wherein R.sup.1 -R.sup.7, A, Z and n are as described in the Summary of the Invention that are inhibitors of procollagen C-proteinase, pharmaceutical compositions containing them, methods for their use and methods for their p
6933142 HEC-G1CNAC6ST August 23, 2005
Mammalian glycosylsulfotransferases expressed in high endothelial cells (HEC-GLCNAC6ST) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, in
6903086 Alkoxycarbonylamino benzoic acid or alkoxycarbonylamino tetrazolyl phenyl derivatives as IP anta June 7, 2005
This invention relates to compounds which are generally IP receptor antagonists and which are represented by Formula I: ##STR1##wherein G.sup.1 is selected from the group consisting of a, b.sup.1 and b.sup.2, ##STR2##and A and G.sup.2 are as defined in the specification; or pharmaceu
6900336 8-aza-11-deoxy prostaglandin analogues May 31, 2005
This invention relates to compounds which are generally EP.sub.4 receptor agonists and which are represented by Formula I: ##STR1##wherein A is a --CH.sub.2 --CH.sub.2 --, or --CH.dbd.CH--; B is absent, an aryl, or heteroaryl group; R.sup.1 is alkyl, alkenyl, alkynyl, cycloalkylalkyl
6900220 Quinazolone derivatives as alpha 1A/B adrenergic receptor antagonists May 31, 2005
This invention relates to compounds which are generally alpha-1A/B adrenoceptor antagonists and which are represented by Formula I: ##STR1##wherein Z is --C(O)-- or --S(O).sub.2 --, X is carbon or nitrogen, Y is carbon, and X--Y considered together are two adjoining atoms of the ring
6893842 T-type calcium channel variants; compositions thereof; and uses May 17, 2005
The invention provides TCCV-1 or TCCV-2 from human, reagents related thereto including polynucleotides encoding TCCV-1 or TCCV-2, purified polypeptides, and specific antibodies. Methods of making and using these reagents, in particular, methods for screening compounds which modulate
6872744 Indole derivatives as anti-inflammatory agents March 29, 2005
This invention relates to compounds, which are generally anti-inflammatory and analgesic compounds, and which are represented by Formula I: ##STR1##wherein A is a --CH.sub.2 --, --O--, --S--, or --S(O)--; and the other substituents are as defined in the specification; or individual isome
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