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Surface Logix, Inc. Patents
Assignee:
Surface Logix, Inc.
Address:
Brighton, MA
No. of patents:
35
Patents:












Patent Number Title Of Patent Date Issued
7476523 Method of patterning a surface using a deformable stamp January 13, 2009
A deformable stamp for patterning a surface. The stamp can be placed in contact with an entire 3-dimensional object, such as a rod, in a single step. The stamp can also be used to pattern the inside of a tube or rolled over a surface to form a continuous pattern. The stamp may also be
7439056 Peelable and resealable devices for arraying materials October 21, 2008
Devices and methods for performing assays on materials, particularly biological materials, are provided. The devices and methods make use of self-sealing members, which can be applied to a flat surface to form wells to facilitate immobilization of materials on the flat surface, then
7422651 Apparatus and method for handling membranes September 9, 2008
A method for applying a pattern to a target surface includes the steps of applying a coating of membrane material over a selected portion of a substrate. The substrate imparts a pattern to the membrane material corresponding to a pattern to be applied to the target surface. A support
7419823 Device and method for monitoring leukocyte migration September 2, 2008
A device for monitoring leukocyte migration is provided. The invention also provides a method of using the device to monitor leukocyte migration in the presence of physiological shear flow and therefore simulate physiological conditions of a blood vessel in vivo. The invention further
7374906 Biological assays using gradients formed in microfluidic systems May 20, 2008
The present invention discloses a device for monitoring chemotaxis or chemoinvasion. The present invention further provides a flexible assay system and numerous assays that can be used to test biological interactions and systems. Laminar flow gradients are employed that mimic gradien
7371563 Peelable and resealable devices for biochemical assays May 13, 2008
Devices and methods for performing assays on materials, particularly biological materials, are provided. The devices and methods make use of self-sealing members, which can be applied to a flat surface to form wells to facilitate immobilization of materials on the flat surface, then
7364899 Device for monitoring haptotaxis April 29, 2008
The present invention discloses a device for monitoring haptotaxis including a housing defining a chamber. The chamber comprises: a first well region including at least one first well, the first well configured to receive a test agent therein and further including biomolecules immobi
7351575 Methods for processing biological materials using peelable and resealable devices April 1, 2008
Devices and methods for performing assays on materials, particularly biological materials, are provided. The devices and methods make use of self-sealing members, which can be applied to a flat surface to form wells to facilitate immobilization of materials on the flat surface, then
7338613 System and process for automated microcontact printing March 4, 2008
An automated process for microcontact printing is provided, comprising the steps of providing a substrate and a stamp; automatically aligning the substrate and stamp so that the stamp is aligned relative to the substrate to impart a pattern to the substrate at a desired location and
7326563 Device and method for monitoring leukocyte migration February 5, 2008
A device for monitoring leukocyte migration is provided. The device generally includes a plurality of chambers, each chamber including a channel in which leukocyte migration mediators or endothelial cells are disposed therein. The device is fabricated in the footprint of a standard m
7285412 Device for magnetic immobilization of cells October 23, 2007
The present invention relates to an apparatus and methods that immobilize one or more cells associated with magnetic material on a substrate on which are located one or more magnetic receptacle(s). Alternatively, in another aspect the present invention, the device arrays cells associated
7244598 Biomolecule arrays July 17, 2007
Array systems that facilitate the simultaneous monitoring of many interactions between biological molecules and the analysis of cellular protein interactions with high throughput. The present invention provides methods and arrays for analyzing biochemical pathways by forming an array
7211209 Method of making device for arraying biomolecules and for monitoring cell motility in real-time May 1, 2007
The invention relates to devices, devices for arraying biomolecules, including cells, methods for arraying biomolecules, assays for monitoring cellular movement, and systems for monitoring cellular movement. The devices include a support; a first layer configured to be placed in flui
7169578 Cell isolation and screening device and method of using same January 30, 2007
The present invention provides methods and devices for screening a single cell or a small group of cells for a desired biological activity. In particular, the present invention provides for delivering cell(s) to a plurality of cell isolation regions of a cell isolation device, transf
7169577 Cell isolation and screening device and method of using same January 30, 2007
The present invention provides methods and devices for screening a single cell or a small group of cells for a desired biological activity. In particular, the present invention provides for delivering cell(s) to a plurality of cell isolation regions of a cell isolation device, transf
7166459 Test device and method of making same January 23, 2007
The present invention discloses a test device including a support member; a top member mounted to the support member, wherein in the support member and the top member are configured such that they together define a discrete chamber. The discrete chamber includes a first well region i
7128631 Soft lithographic process for fabricating integrated ITO electrode-liquid crystal alignment laye October 31, 2006
A system and method are described for self-aligning electrodes for color filters of passive matrix displays.
7123764 Image processing method for use in analyzing data of a chemotaxis or haptotaxis assay October 17, 2006
An image processing method for use in analyzing image data of a cellular migration assay. The method includes defining a major axis within the image data that is perpendicular to an orientation of channels in the image data, determining an aggregate light intensity within the image d
7033821 Device for monitoring cell motility in real-time April 25, 2006
The invention relates to devices, devices for arraying biomolecules, including cells, methods for arraying biomolecules, assays for monitoring cellular movement, and systems for monitoring cellular movement. The devices include a support; a first layer configured to be placed in flui
7033819 System for monitoring cell motility in real-time April 25, 2006
The invention relates to devices, devices for arraying biomolecules, including cells, methods for arraying biomolecules, assays for monitoring cellular movement, and systems for monitoring cellular movement. The devices include a support; a first layer configured to be placed in flui
7001740 Methods of arraying biological materials using peelable and resealable devices February 21, 2006
Devices and methods for performing assays on materials, particularly biological materials, are provided. The devices and methods make use of self-sealing members, which can be applied to a flat surface to form wells to facilitate immobilization of materials on the flat surface, then
6982171 Cell motility and chemotaxis test device and methods of using same January 3, 2006
The present invention discloses a device for monitoring chemotaxis or chemoinvasion including a housing comprising: a support member and a top member, the top member mounted to the support member by being placed in substantially fluid-tight conformal contact with the support member. The
6967074 Methods of detecting immobilized biomolecules November 22, 2005
Devices and methods for performing assays on materials, particularly biological materials, are provided. The devices and methods make use of self-sealing members, which can be applied to a flat surface to form wells to facilitate immobilization of materials on the flat surface, then
6937804 Non-linear photonic switch and method of making the same August 30, 2005
A photonic switch according to the present invention may be formed using one of a selected group of non-linear optical materials. Each of the materials within this group has a refractive index that demonstrates a substantial peak as a function of wavelength, where the peak occurs at a
6921660 Cell motility and chemotaxis test device and methods of using same July 26, 2005
The present invention discloses a device for monitoring chemotaxis or chemoinvasion including a housing comprising: a support member and a top member, the top member mounted to the support member by being placed in substantially fluid-tight conformal contact with the support member. The
6893851 Method for arraying biomolecules and for monitoring cell motility in real-time May 17, 2005
The invention relates to devices, devices for arraying biomolecules, including cells, methods for arraying biomolecules, assays for monitoring cellular movement, and systems for monitoring cellular movement. The devices include a support; a first layer configured to be placed in flui
6885790 Non-linear photonic switch April 26, 2005
A photonic switch may be formed using one of a selected group of non-linear optical materials. Each of the materials within this group has a refractive index that demonstrates a substantial peak as a function of wavelength. The photonic switch includes a positive gain, and thus acts as
6864065 Assays for monitoring cell motility in real-time March 8, 2005
The invention relates to devices, devices for arraying biomolecules, including cells, methods for arraying biomolecules, assays for monitoring cellular movement, and systems for monitoring cellular movement. The devices include a support; a first layer configured to be placed in flui
6844184 Device for arraying biomolecules and for monitoring cell motility in real-time January 18, 2005
The invention relates to devices, devices for arraying biomolecules, including cells, methods for arraying biomolecules, assays for monitoring cellular movement, and systems for monitoring cellular movement. The devices include a support; a first layer configured to be placed in flui
6833040 Apparatus and method for handling membranes December 21, 2004
A method for applying a pattern to a target surface includes the steps of applying a coating of membrane material over a selected portion of a substrate. The substrate imparts a pattern to the membrane material corresponding to a pattern to be applied to the target surface. A support
6818403 Method of monitoring haptotaxis November 16, 2004
The present invention discloses a method of monitoring haptotaxis comprising: providing a device for monitoring haptotaxis having a housing defining a chamber. The chamber includes: a first well region including at least one first well, the first well region configured to receive a test
6811968 Method of monitoring cell motility and chemotaxis November 2, 2004
The present invention discloses a method of monitoring chemotaxis or chemoinvasion comprising: providing a device for monitoring chemotaxis. The device includes a support member; a top member mounted to the support member by being placed in substantially fluid-tight, conformal contact
6803205 Methods of measuring enzyme activity using peelable and resealable devices October 12, 2004
Devices and methods for performing assays on materials, particularly biological materials, are provided. The devices and methods make use of self-sealing members, which can be applied to a flat surface to form wells to facilitate immobilization of materials on the flat surface, then
6770721 Polymer gel contact masks and methods and molds for making same August 3, 2004
The present invention relates to elastomeric contact masks, and methods of making these contact masks by complementary molding using complementary molds. The contact masks are made of polymer gels, including hydrogel materials. The complementary molds of the present invention include at
6699665 Multiple array system for integrating bioarrays March 2, 2004
A multiple level micro-array system for integrating micro-arrays of biomolecules, including biological, chemical and biochemical elements. The multiple level micro-arrays are formed using soft lithography techniques and elastomeric membranes to shield or pattern various portions of a

 
 
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