| Patent Number |
Title Of Patent |
Date Issued |
| RE32761 |
3-arylcarbonyl and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, compositions and use |
October 4, 1988 |
| 3-Arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, useful as analgesic, anti-rheumatic and anti-inflammatory agents, are prepared by reacting a 3-arylcarbonyl- or 3-cycloalkylcarbonylindole with an aminoalkyl halide in the presence of an acid-acceptor; by reacting a 1- |
| RE32300 |
Basic amino or ammonium antimicrobial agent-polyethylene glycol ester surfactant-betaine and/or |
December 2, 1986 |
| Basic amino or ammonium antimicrobial agent (especially bisbiguanide, quarternary ammonium salt and bispyridine)-polyethylene glycol ester surfactant-betaine and/or amine oxide surfactant antimicrobial skin cleansing compositions and method of use thereof are disclosed. |
| RE30241 |
Esters of 3-(hydroxy or hydroxymethyl)-4-hydroxyphenyl aminomethyl ketones |
March 25, 1980 |
| Mono-, di- and tri-esters of 3-(hydroxy or hydroxymethyl)-4-hydroxy-alpha-(aminomethyl)benzyl alcohols, obtained by methods involving reduction of the corresponding mono- and di-ester ketones, are useful for producing sympathomimetic effects, such as bronchodilation, of long duration |
| RE30024 |
4-Amino (or hydrazino)-2-(pyridinyl)pyrimidines |
June 5, 1979 |
| Compounds useful as anti-allergic agents are 2-Q-4-[XZC.dbd.C(R)NH]-5-R.sub.1 -6-R.sub.2 -pyrimidines (I), where Q is 4- or 3- or 2-pyridinyl or 4- or 3- or 2-pyridinyl having one or two lower-alkyl substituents or N-oxide thereof, R is hydrogen or lower-alkyl, R.sub.1 is hydrogen, l |
| RE29943 |
Aminomethanobenzazocine intermediates |
March 20, 1979 |
| N-Alkylated-8-aminated-2,6-methano-3-benzazocines, useful as strong analgesics, are prepared by one route comprising reduction of 8-nitro intermediates or by another route comprising Birch type reduction of 8-methoxy intermediates followed by dehydration-rearrangement of the oximes o |
| D316369 |
Combined bottle and measuring cup cover |
April 23, 1991 |
|
| D315671 |
Bottle |
March 26, 1991 |
|
| D314917 |
Combined overcap and aerosol actuator |
February 26, 1991 |
|
| D314915 |
Bottle closure |
February 26, 1991 |
|
| D308481 |
Bottle |
June 12, 1990 |
|
| D307241 |
Bottle |
April 17, 1990 |
|
| D307113 |
Bottle |
April 10, 1990 |
|
| D286506 |
Dispensing container for facial tissues or the like |
November 4, 1986 |
|
| D285657 |
Packaging container for wet tissues or the like |
September 16, 1986 |
|
| D284894 |
Medicament dispenser spoon |
July 29, 1986 |
|
| D284743 |
Bottle |
July 22, 1986 |
|
| D284741 |
Bottle |
July 22, 1986 |
|
| D280384 |
Container for liquids |
September 3, 1985 |
|
| D274584 |
Holder for article dispenser |
July 10, 1984 |
|
| D267782 |
Dispensing cap for a container |
February 1, 1983 |
|
| D267781 |
Dispensing cap for a container |
February 1, 1983 |
|
| D265626 |
Dispensing container |
August 3, 1982 |
|
| D265289 |
Bellowed dispensing bottle |
July 6, 1982 |
|
| D263559 |
Pharmaceutical package |
March 30, 1982 |
|
| 5567810 |
Nuclease resistant compounds |
October 22, 1996 |
| Compounds, compositions and methods for inhibiting gene expression are disclosed. The compounds comprise oligonucleotide sequences of from about 9 to about 200 bases having a diol at either or both termini. Preferred diols are polyalkyleneglycols, preferably polyethyleneglycols. Phar |
| 5338475 |
Carpet cleaning composition with bleach |
August 16, 1994 |
| A carpet cleaning composition is disclosed. The composition contains, on a weight-to-weight basis,a. about 0.30 to 2.2 percent of hydrogen peroxide;b. from about 0.05 to about 5.0 percent of a nonionic, anionic or amphoteric surfactant or mixture thereof; andc. a pH in the range above 3.5 an |
| 5308843 |
Method of inhibiting mammalian topoisomerase II and malignant cell growth in mammals, with subst |
May 3, 1994 |
| A method of inhibiting mammalian topoisomerase II and inhibiting the growth and inducing the regression of malignant cells in mammals by the action of a (S)-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine or -benzothiazine of the formula ##STR1## wherein R.sub.1 is |
| 5288479 |
Extrudable elastic oral pharmaceutical gel compositions and metered dose dispensers containing t |
February 22, 1994 |
| Extrudable elastic oral pharmaceutical gel compositions, especially containing aetaminophen as the therapeutically active agent, and manually operable metered dose dispensers containing them and method of making and method of use thereof are disclosed. |
| 5254592 |
Multiply substituted anilines, phenols and pyridines-immunomodulating agents |
October 19, 1993 |
| In accordance with the present invention, certain multiply substituted anilines, phenols and pyridines and pharmaceutically acceptable salts thereof are provided which mimic IL-1 activity by inducing IL-2 synthesis and subsequent IL-2 receptor expression. Specifically, the invention |
| 5245022 |
Exonuclease resistant terminally substituted oligonucleotides |
September 14, 1993 |
| Compounds, compositions and methods for inhibiting gene expression are disclosed. The compounds comprise oligonucleotide sequences of from about 9 to about 200 bases having a diol at either or both termini. Preferred diols are polyalkyleneglycols, preferably polyethyleneglycols. Phar |
| 5223268 |
Low solubility drug-coated bead compositions |
June 29, 1993 |
| Low solubility drug coated bead compositions, capsules filled therewith and method of preparation thereof, especially wherein the low solubility drug is an antiandrogenic steroid and most especially wherein the antiandrogenic steroid is (5.alpha.,17.alpha.)1'-(methylsulfonyl)-1'H-pre |
| 5213811 |
Oral sustained-release drug compositions |
May 25, 1993 |
| Sugar or sugar/starch beads coated with a first coating of a drug, for example 1,2-dihydro-6-(lower alkyl)-2-oxo-5-(4-pyridinyl)-nicotinonitrile (milrinone), hydroxypropyl methylcellulose or hydroxypropyl cellulose and a plasticizer selected from triacetin, diacetylated monoglycerides, |
| 5208336 |
Selenomerocyanines and processes for preparation and methods of use and compositions thereof |
May 4, 1993 |
| Selenomerocyanines, for example the compound having the structural formula ##STR1## a process for preparation thereof, methods of use thereof as photosensitizers for generation of singlet oxygen, virus inactivation and cancer cell inactivation, and photosensitized silver halide photo |
| 5206231 |
2,5-benzodiazocine antiarrhythmic agents |
April 27, 1993 |
| Novel 2,5-benzodiazocines of formulas II and IV, pharmaceutical compositions containing them, processes for preparing them and methods of treating cardiac arrhythmias in mammals utilizing them. ##STR1## |
| 5175178 |
1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
December 29, 1992 |
| Compounds of the formulas ##STR1## wherein: Y is an alkylene bridge of 3-9 carbon atoms;R' is lower-alkyl or hydroxy-lower-alkyl of 1-5 carbon atoms;R.sub.1 and R.sub.2 are hydrogen, halogen, lower-alkyl, lower-alkoxy, nitro, lower-alkoxycarbonyl or trifluoromethyl; andR.sub.8 is hydroge |
| 5175177 |
1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
December 29, 1992 |
| Compounds of the formula ##STR1## wherein: Y is alkylene of 3 to 9 carbon atoms;R.sub.1 is lower-alkyl, lower-alkoxy-(C.sub.1-3 -alkyl), lower-alkoxycarbonyl, cyclopropyl or trifluoromethyl;R.sub.2 and R.sub.3 independently are hydrogen, lower-alkyl, halogen, lower-alkoxy, nitro, tri |
| 5172512 |
Trap for catching mice and rats |
December 22, 1992 |
| A trap for catching mice and rats includes a standard mousetrap mounted within a two-part housing. The standard mousetrap includes a tab which projects through a slot an arcuate upper wall of one portion of the housing, allowing one to cock the trap from the exterior of the housing. |
| 5169853 |
Pyridinyl-quinolone compounds, their preparation and use |
December 8, 1992 |
| Fluorinated 1- cyclopropyl-7-(substituted-pyridinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxy lic acids of the formula ##STR1## wherein R is hydrogen, R' and R" are hydrogen or fluoro, and Z is 3- or 4-pyridinyl substituted by alkyl groups or substituted alkyl groups, are superior |
| 5152431 |
Pump apparatus for dispensing a selected one of a plurality of liquids |
October 6, 1992 |
| A single pump assembly is used to dispense liquid from a selected one of a plurality of compartments in a container vessel. The pump assembly is detachably mounted on the container vessel and rotates with respect to the container vessel to select the liquid to be pumped. |
| 5147884 |
Preservative for aqueous products and systems |
September 15, 1992 |
| An antimicrobial composition for preserving products or systems containing an aqueous phase comprising from 10 to 60% by weight or tert.-butyl hydroperoxide, from 3 to 50% by weight of a monophenylglycol ether of formulas I or II herein, and the remainder a diluent which is water, an |
| 5145684 |
Surface modified drug nanoparticles |
September 8, 1992 |
| Dispersible particles consisting essentially of a crystalline drug substance having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 400 nm, methods for the preparation of such particles and d |
| 5141803 |
Nonwoven wipe impregnating composition |
August 25, 1992 |
| An aqueous composition for impregnating a nonwoven wipe having a pH of from 3.5 to 4.5 and containing a preservative system comprising potassium sorbate, citric acid, disodium EDTA and a cationic biocide selected from polyhexamethylene biguanide hydrochloride and poly[oxyethylene(dim |
| 5134135 |
Antiandrogenic sulfonylsteroidooxazoles |
July 28, 1992 |
| 2'-Alkylsulfonylsteroido[2,3-d]oxazoles, for example 2'-methylsulfonyl-5.alpha.-pregn-2-en-20-yno[2,3-d]oxazol-17.beta.-ol, which are useful as antiandrogenic agents, and proceses for preparation, method of use and compositions thereof are disclosed. |
| 5132321 |
Anticoagulant/surfactant rodenticidal compositions and method |
July 21, 1992 |
| Rodenticidal compositions comprising an anticoagulant type rodenticide in combination with a fluorosurfactant of the amphoteric, anionic or cationic type, optionally admixed with a cereal grain bait, and a method of killing rodents by oral administration of such compositions. |
| 5122541 |
Sprayable surface disinfectant |
June 16, 1992 |
| A sprayable aqueous disinfecting composition for disinfecting hard surfaces comprising 20 to 30% by weight of a mixture of ethyl alcohol and isopropyl alcohol in a weight ratio of 1:2 to 2:1, 0.05 to 0.5% by weight of a mixture of a primary or secondary C.sub.10-18 -alkane sulfonate and/ |
| 5115951 |
Dispensing wand and combination of dispensing wand with container |
May 26, 1992 |
| An L-shaped dispensing wand has one end fitted into an insert previously snap fitted into the neck of a container, such as a rectangular metal can. The wand has an array of holes along the top side thereof which face downward when the can is inverted to sprinkle the area beneath the can. |
| 5112820 |
Anti-glaucoma compositions containing 2- and 3-aminomethyl-6-arylcarbonyl- or 6-phenylthio-2 |
May 12, 1992 |
| Antiglaucoma compositions containing 2- and 3-aminomethyl-6-arylcarbonyl- or 6-phenylthio-2,3-dihydropyrrolo-[1,2,3-de]-1,4-benzoxazines as the active component thereof and the method of use thereof in the treatment of glaucoma. |
| 5110821 |
1,3,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
May 5, 1992 |
| Compounds of the formula ##STR1## wherein: Y is an alkylene bridge of 3-9 carbon atoms;R' is lower-alkyl or hydroxy-lower-alkyl or 1-5 carbon atoms;R.sub.1 and R.sub.2 are hydrogen, halogen, lower-alkyl, lower-alkoxy, nitro, lower-alkoxycarbonyl or trifluoromethyl; andR.sub.8 is hydrogen |
| 5109135 |
2- or 3-aminomethyl-4-amino-3,4-dihydro-2H-1,4-benzoxazine intermediates |
April 28, 1992 |
| 2- and 3-Aminomethyl-6-arylcarbonyl-2,3-dihydropyrrolo[1,2,3-de]-1,4-benzoxazines , useful as analgesic agents, are prepared either by reaction of a 2- or 3-aminomethyl-2,3-dihydropyrrolo[1,2,3-de]-1,4-benzoxazine with an arylcarboxylic acid halide in the presence of a Lewis acid or b |
| 5106844 |
Imidazo[2,2-b][3]benzazepine and pyrimido[2,1-b][3]benzazepine antiarrhythmic agents |
April 21, 1992 |
| Novel imidazo[2,1-b][3]benzazepines and pyrimido[2,1-b][3]benzazepines of formula I, pharmaceutical compositions containing them, methods for treating cardiac arrhythmia in mammals utilizing them, and processes for synthesizing them. ##STR1## |
