| Patent Number |
Title Of Patent |
Date Issued |
| 7432366 |
Moraxella catarrhalis BASB034 polypeptides and used thereof |
October 7, 2008 |
| Provided are Moraxella catarrhalis BASB034 polypeptides and immunogenic fragments of BASB034 polypeptides. Preferably, the immunogenic fragments have at least 15 amino acids that match an aligned contiguous segment of SEQ ID NOs:2, 4, 6 or 8. The immunogenic fragments, when administered |
| 7375091 |
HER-2/neu fusion proteins |
May 20, 2008 |
| The present invention is generally directed to HER-2/neu fusion proteins, nucleic acid molecules encoding HER-2/neu fusion proteins, viral vectors expressing HER-2/neu fusion proteins, and pharmaceutical compositions (e.g., vaccines) comprising the HER-2/neu fusion proteins and/or nuclei |
| 7371390 |
Vaccine against HBV and HPV |
May 13, 2008 |
| Novel combined vaccine compositions are provided, comprising a hepatitis B viral antigen and optionally in addition one or more of the following: an EBV antigen, a hepatitis A antigen or inactivated attenuated virus, a herpes simplex viral antigen, a VZV antigen, a Toxoplasma gondii anti |
| 7357936 |
Adjuvant systems and vaccines |
April 15, 2008 |
| The present invention provides vaccine and adjuvant formulation comprising an immunostimulant and a metal salt. The immunostimulant is adsorbed onto a particle of metal salt and the resulting particle is essentially devoid of antigen. |
| 7348009 |
Recombinant allergen with reduced enzymatic activity |
March 25, 2008 |
| The present invention provides a novel treatment for allergy comprising a recombinant allergen with reduced enzymatic activity, thereby reducing the potential for an allergic response upon contact with a wild-type allergen. |
| 7285280 |
Vaccine |
October 23, 2007 |
| The invention provides an attenuated rotavirus population comprising a single variant or substantially a single variant which is defined by a nucleotide sequence encoding at least one of the major viral proteins designated as VP4 and VP7. The invention particularly provides a rotavir |
| 7238349 |
Composition |
July 3, 2007 |
| The invention provides a monovalent influenza vaccine comprising a low dose of egg-derived influenza virus antigen from an influenza virus strain that is associated with a pandemic outbreak or has the potential to be associated with a pandemic outbreak, in combination with an alumini |
| 7220551 |
Composition |
May 22, 2007 |
| Novel combined vaccine compositions are provided, comprising a herpes simplex virus (HSV) antigen and a HPV antigen and optionally in addition one or more of the following: an EBV antigen, a hepatitis A antigen or inactivated attenuated virus, a hepatitis B viral antigen, a VZV antigen, |
| 7198920 |
HER-2/neu fusion proteins |
April 3, 2007 |
| The present invention is generally directed to HER-2/neu fusion proteins, nucleic acid molecules encoding HER-2/neu fusion proteins, viral vectors expressing HER-2/neu fusion proteins, and pharmaceutical compositions (e.g., vaccines) comprising the HER-2/neu fusion proteins and/or nuclei |
| 7192065 |
System for providing communication between the interior and the exterior of a compartment |
March 20, 2007 |
| A system for making a connection between the interior and exterior of a compartment, comprising a door opening through the compartment wall, a connector body which can engage with the wall, and having a connection port through it, and a removable cover on the connector body. The body is |
| 7144703 |
Composition |
December 5, 2006 |
| Novel vaccine compositions are provided comprising a hepatitis B antigen formulated with aluminium phosphate. The vaccine compositions may additionally contain an inactivated hepatitis A virus, aluminium hydroxide and formol. The combined hepatitis A and B vaccine formulations can, i |
| 7101560 |
Combination vaccine for administration to adolescents |
September 5, 2006 |
| Novel combined vaccine compositions are provided, comprising a herpes simplex virus (HSV) antigen and a HPV antigen and optionally in addition one or more of the following: an EBV antigen, a hepatitis A antigen or inactivated attenuated virus, a hepatitis B viral antigen, a VZV antigen, |
| 7071321 |
Polynucleotides and polypeptides BASB033 from Neisseria meningitidis and their uses |
July 4, 2006 |
| The invention provides BASB033 polypeptides and polynucleotides encoding BASB033 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses. |
| 6991929 |
Hepatitis A vaccines |
January 31, 2006 |
| A process for the production of inactivated Hepatitis A virus substantially free of host cell contamination is described, the process comprising: a) culturing Hepatitis A virus and harvesting a Hepatitis A preparation; b) treating said Hepatitis A preparation with a protease; and the |
| 6936255 |
Vaccine composition comprising herpes simplex virus and human papilloma virus antigens |
August 30, 2005 |
| Novel combined vaccine compositions are provided, comprising a herpes simplex virus (HSV) antigen and a HPV antigen and optionally in addition one or more of the following: an EBV antigen, a hepatitis A antigen or inactivated attenuated virus, a hepatitis B viral antigen, a VZV antigen, |
| 6932972 |
Combined vaccine compositions |
August 23, 2005 |
| Novel combined vaccine composition preferentially for administration to adolescents are provided, comprising a hepatitis B viral antigen and a herpes simplex viral antigen and optionally in addition one or more of the following: an EBV antigen, a hepatitis A antigen or inactivated attenu |
| 6899884 |
Vaccine against mumps containing a jeryl-lynn virus strain |
May 31, 2005 |
| A new mumps vaccine is presented, comprising a homogeneous pure isolate derived from the Jeryl-Lynn strain of mumps virus. In a preferred embodiment of the invention the vaccine produces higher seroconversion and anitbody titres than know commercial vaccines. |
| 6893644 |
Hepatitis vaccines containing 3-O-deacylated monophoshoryl lipid A |
May 17, 2005 |
| A vaccine formulation for the treatment or prophylaxis of hepatitis, especially hepatitis, especially hepatitis B, infections is provided comprising the hepatitis antigen and a suitable carrier such as alum in combination with 3-O-deacylated monophosphoryl lipid. A combination vaccin |
| 6846489 |
Vaccines containing a saponin and a sterol |
January 25, 2005 |
| A novel adjuvant composition comprising a sterol (e.g., cholesterol, .beta.-sitosterol, stigmasterol, ergosterol, and ergocalciferol) and saponin fraction (e.g., QS21, also known as QA21) in the form of an immunostimulating complex, or ISCOM, is disclosed. QS21 is an immunologically |
| 6764834 |
BASB019 proteins and genes from Moraxella catarrhalis, antigens, antibodies, and uses |
July 20, 2004 |
| The invention provides BASB019 polypeptides and polynucleotides encoding BASB019 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses. |
| 6756040 |
Vaccine composition comprising a polysaccharide conjugate antigen adsorbed onto aluminum phospha |
June 29, 2004 |
| The invention relates to a vaccine formulation for the prevention of Haemophilus Influenzae Type B (Hib) infections and where the antigen is adsorbed onto aluminum phosphate. The invention also relates to a multivalent vaccines, that is a vaccine for the amelioration or treatment of |
| 6709657 |
BASB013 DNA and proteins from Neisseria meningitidis |
March 23, 2004 |
| The invention provides BASB013 polypeptides and polynucleotides encoding BASB013 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses. |
| 6706494 |
BASB028 polypeptides and polynucleotides encoding therefor from moraxella catarrhalis |
March 16, 2004 |
| The invention provides BASB028 polypeptides and polynucleotides encoding BASB028 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses. |
| 6706271 |
Cloning of BASB023 antigen from Moraxella catarrhalis |
March 16, 2004 |
| The invention provides BASB023 polypeptides encoding BASB023 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses. |
| 6706270 |
Compounds |
March 16, 2004 |
| The invention provides BASB041, 43, 44 and 48 polypeptides and polynucleotides encoding BASB041, 43, 44 and 48 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses. |
| 6706269 |
Moraxella catarrhalis PILQ proteins |
March 16, 2004 |
| The invention provides BASB031 polypeptides and polynucleotides encoding BASB031 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses. |
| 6696062 |
BASB006 polypeptides from Neisseria meningitidis and immunogenic compositions thereof |
February 24, 2004 |
| Provided are BASB006 polypeptides from Neisseria meningitidis. Also provided are fusion proteins containing BASB006 polypeptides. The invention also relates to immunogenic compositions containing BASB006 polypeptides. |
| 6684918 |
Teat nozzle for dosing device with connection means |
February 3, 2004 |
| A teat nozzle suitable for pediatric oral dosing of a fluid medicament comprising a tubular conduit which is engageable with a socket, and has at least one engagement part which can engage with an internal thread in the socket. The teat nozzle facilitates connection between the conduit a |
| 6635255 |
CASB414:antigen overexpressed in several tumors |
October 21, 2003 |
| CASB414 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CASB414 polypeptides and polynucleotides in diagnostics, and vaccines for prophylactic and therapeutic treatment of c |
| 6627728 |
Compounds from moraxella catarrhalis |
September 30, 2003 |
| The invention provides BASB010 polypeptides and polynucleotides encoding BASB010 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses. |
| 6623739 |
Vaccines |
September 23, 2003 |
| The present invention provides vaccine compositions comprising an oil-in-water emulsion optionally with 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccine compositions are potent inducers of a range of immune responses. |
| 6613335 |
Polypeptides from moraxella (branhamella) catarrhalis |
September 2, 2003 |
| Provided are BASB011 polypeptides and polynucleotides encoding BASB011 polypeptide from Moraxella catarrhalis. Also provided are immunogenic uses. |
| 6600013 |
Moraxella catarrhalis BASB034 polypeptides and uses thereof |
July 29, 2003 |
| Provided are Moraxella catarrhalis BASB034 polypeptides and immnunogenic fragments of BASB034 polypeptides Preferably, the immunogenic fragments have at least 15 amino acids that match an aligned contiguous segment of SEQ ID NOs:2, 4, 6 or 8. The immunogenic fragments, when administered |
| 6544518 |
Vaccines |
April 8, 2003 |
| The present invention relates to adjuvant compositions which are suitable to be used in vaccines. In particular, the adjuvant compositions of the present invention comprises a saponin and an immunostimulatory oligonucleotide, optionally with a carrier. Also provided by the present in |
| 6506386 |
Vaccine comprising an iscom consisting of sterol and saponin which is free of additional deterge |
January 14, 2003 |
| The present invention provides an improved adjuvant formulation and a process for producing said adjuvant. The adjuvant comprises an ISCOM structure comprising a saponin, said ISCOM structure being devoid of additional detergent. |
| 6500432 |
Method to enhance an immune response of nucleic acid vaccination |
December 31, 2002 |
| This invention provides a method to enhance an immune response of nucleic acid vaccination by simultaneous administration of a polynucleotide and a polypeptide of interest. |
| 6488934 |
Hepatitis B vaccine |
December 3, 2002 |
| A novel vaccine formulation is provided, comprising a hepatitis B component, particularly hepatitis B surface antigen, in combination with aluminum phosphate and 3 de-O-acylated monophosphoryl lipid A. |
| 6451320 |
Combined hepatitis and herpesvirus antigen compositions |
September 17, 2002 |
| Novel combined vaccine compositions preferentially for administration to adolescents are provided, comprising a hepatitis B viral antigen and a herpes simplex viral antigen and optionally in addition one or more of the following: an EBV antigen, a hepatitis A antigen or inactivated atten |
| 6375945 |
Adjuvant compositions for vaccines |
April 23, 2002 |
| The present invention pertains to improved adjuvant compositions comprising a mixture of a saponin adjuvant such as QS21 with monophosphoryl lipid A or derivative thereof such as 3D-MPL and interleukin 12. These compositions are useful in a range of prophylactic and therapeutic appli |
| 6372227 |
Vaccines |
April 16, 2002 |
| The present invention relates to oil in water emulsion compositions, their use in medicine, in particular to their use in augmenting immune responses to a wide range of antigens, and to methods of their manufacture; the compositions having oil phase and an aqueous phase, a sterol and a |
| 6342224 |
Recombinant papillomavirus vaccine and method for production and treatment |
January 29, 2002 |
| The present invention relates to fusions proteins, comprising a protein or part of a protein that provides T helper epitopes and an antigen from a human-papilloma virus. In particular the invention relates to fusion proteins comprising an E6 or E7 protein from HPV strain 16 or 18 linked |
| 6306625 |
Method for obtaining expression of mixed polypeptide particles in yeast |
October 23, 2001 |
| The present invention provides a method for obtaining expression of a mixed hepatitis B surface antigen particle, e.g., a particle of mixed polypeptide composition, in yeast. Also disclosed is a method for obtaining multimeric structures presenting two or more polypeptides by express |
| 6267256 |
Storage devices |
July 31, 2001 |
| For storage of syringes, a support rack comprising a plurality of elongate fingers (2) connected together at one end by a spine member (1) is used. The fingers (2) define parallel support channels (5) open at one end, and the syringes are stored in the channels (5) with their lips or win |
| 6258078 |
Luer connector with rotationally engaging piercing luer |
July 10, 2001 |
| A luer connector which facilitates connection of a hypodermic syringe to the vial, comprising a luer connectable to a syringe and which extends to a sharpened end capable of being driven through a puncturable vial closure to thereby puncture the closure; a luer support, mountable on a vi |
| 6146632 |
Vaccines |
November 14, 2000 |
| The present invention provides vaccine compositions comprising an oil-in-water emulsion optionally with 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccines compositions are potent inducers of a range of immune responses. |
| 6012595 |
Storage devices |
January 11, 2000 |
| For storage of syringes, a support rack comprising a plurality of elongate fingers (2) connected together at one end by a spine member (1) is used. The fingers (2) define parallel support channels (5) open at one end, and the syringes are stored in the channels (5) with their lips or win |
| 5972346 |
Hepatitis B vaccine |
October 26, 1999 |
| A novel vaccine formulation is provided, comprising a hepatitis B component, particularly hepatitis B surface antigen, in combination with aluminum phosphate and 3-O-acylated monophosphoryl lipid A. |
