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Sanofi-Aventis Deutschland GmbH Patents
Assignee:
Sanofi-Aventis Deutschland GmbH
Address:
Frankfurt am Main, DE
No. of patents:
185
Patents:


1 2 3 4


Patent Number Title Of Patent Date Issued
RE40558 Therapeutic uses of di-aryl acid derivatives October 28, 2008
The use of diaryl acid derivatives of formula (I) ##STR00001## or pharmaceutically acceptable salts, N-oxides, hydrates or solvates thereof, wherein the variables shown are defined in the disclosure, and their pharmaceutical compositions as PPAR ligand receptor binders. The PPAR li
D600795 Medical injector September 22, 2009
D600794 Medical injector September 22, 2009
D599011 Medical injector August 25, 2009
D599010 Medical injector August 25, 2009
D599009 Medical injector August 25, 2009
D599008 Medical injector August 25, 2009
D598539 Medical injector August 18, 2009
7622611 Pentafluorosulfanylbenzoylguanidines, process for their preparation, use as a medicament or diag November 24, 2009
Pentafluorosulfanylbenzoylguanidines of formula I ##STR00001## wherein R1 to R4 have the meanings stated in the claims, are suitable, for example, as antiarrhythmic medicaments with a cardioprotective component for the prophylaxis of infarction and treatment of infarction and for the
7622275 Aequorin as a growth marker in yeast November 24, 2009
A yeast cell containing constitutively expressed aequorin and methods of using the cells in growth and toxicity assays are disclosed.
7615536 1,4-benzothiazepine 1,1-dioxide derivative, process for its preparation, medicaments comprising November 10, 2009
The invention relates to the compound of the formula (A) and also to its physiologically acceptable salts. The compound is suitable as, for example, a hypolipidemic ##STR00001##
7615360 Use of Saccharomyces cerevisiae erg4 mutants for expressing mammalian glucose transporter November 10, 2009
The invention relates to yeast strains in which a human GLUT4 transport or a human GLUT1 transporter can be functionally expressed and to particular GLUT4 transport proteins which can be functionally expressed particularly readily in yeast strains.
7601863 Use of PPAR agonists for the treatment of congestive heart failure October 13, 2009
The invention describes the use of PPAR agonists of the formulae (I) or (II) ##STR00001## for the treatment of congestive heart failure (CHF).
7598281 Arylcycloakyl-substituted alkanoic acid derivatives useful as peroxisome proliferator-activated October 6, 2009
The present invention comprises compounds and compositions for the treatment of metabolic disorders and more particularly, those insulin-related metabolic disorders of the blood such as hyperlipidemia, diabetes, insulin-resistence and the like comprising acetic acid derivatives with
7589117 Isoindolone derivatives, preparation process and intermediates of this process, their use as med September 15, 2009
The present invention relates to the novel isoindolone derivatives of the formula I ##STR00001## in which R1 to R6 have the meanings stated in the claims. The inventive compounds are suitable as antiarrhythmic medicaments with a cardioprotective component for infarction prophylaxis
7582794 Process for the preparation of substituted 2-(phenoxymethyl)benzoic acids September 1, 2009
The invention relates to a process for the preparation of a compound of the general formula (I) in which a) a compound (II) is reacted in the presence of a base B1 with a compound (III) and ##STR00001## b) the compound (IV) formed as intermediate in step a) is reacted in the p
7579339 Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising the August 25, 2009
One embodiment of the invention relates to compounds of the formula I, ##STR00001## in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification. Other embodiments of the invention relate to physiologically acceptable salts of compounds of formula I, to processes
7576200 Diphenylazetidinones, process for their preparation, medicaments comprising these compounds and August 18, 2009
Compounds of the formula I, ##STR00001## in which R1, R2, R3, R4, R5, and R6 have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.
7576109 1,3,4-oxadiazol-2-ones as PPAR delta modulators and their use thereof August 18, 2009
The present invention is directed to 1,3,4-oxadiazolones, compounds of formula I and their pharmaceutically acceptable salts stereoisomers, tautomers, or solvates thereof. Novel compounds include those of formula I, in which radicals are as defined herein. ##STR00001## The compounds of
7569583 Aryl-substituted polycyclic amines, method for the production thereof, and use thereof as a medi August 4, 2009
The invention relates to aryl-substituted polycyclic amines of the formula I, especially bicyclic amines, and to the physiologically tolerated salts and physiologically functional derivatives thereof; ##STR00001## where the symbols and radicals are explained in the description as well a
7563888 Process for the preparation of diphenyl azetidinone derivatives July 21, 2009
The present invention is a process for the preparation of diphenylazetidinone derivatives of the formula (I) or forms thereof comprising the substituents X, R.sup.1 and/or R.sup.2 as defined herein. More specifically, the invention comprises methods for the preparation of these compo
7563582 Process for screening chemical compounds for modulating the interaction of an EVH1 domain and a July 21, 2009
The invention relates to processes for identifying chemical compounds which are capable of modulating the interaction between VASP and zyxin. VASP or a VASP derivative and zyxin or a zyxin derivative which interact with one another are brought into contact with a chemical compound to be
7560290 Method for the identification of a risk for a thrombogenic disorder by determining the TAFI-Ile3 July 14, 2009
The present invention is directed to a method identifying a risk for a thrombogenic disorder, to a method for selecting patients with a risk for a thrombogenic disorder, to a method for identifying a pharmaceutical for the therapy or prophylaxis of a thrombogenic disorder as well as to a
7550582 Polyamide nucleic acid derivatives and agents, and processes for preparing them June 23, 2009
The present invention relates to PNA derivatives which carry, at the C terminus, or at both the C and N termini of the PNA backbone, one or more phosphoryl radicals. The phosphoryl radicals carry, where appropriate, one or more labeling groups, groups for crosslinking, groups which p
7550257 Process for identifying substances which modulate the activity of hyperpolarization-activated ca June 23, 2009
The present invention provides a process for identifying substances that modulate the activity of hyperpolarization-activated cation channels, and the use of this process.
7544809 Method for the preparation of oxazoles by condensing aromatic aldehydes with .alpha.-ketoximes t June 9, 2009
The present invention is comprised of improved methods in the preparation of oxazoles which results in higher yields with less impurities and contaminants. Oxazoles constitute valuable intermediates in the synthesis of pharmaceutically active substances such as, for example peroxisome
7541464 7-azaindoles, pharmaceutical compositions and their therapeutic applications June 2, 2009
The present invention relates generally to compounds and compositions for the treatment of metabolic diseases and specifically, the present invention relates to compounds that therapeutically modulation and control lipid and/or carbohydrate metabolism and are thus suitable for the pr
7538227 Process for stabilizing 4-halopyridines May 26, 2009
The present invention relates to a process for stabilizing 4-halopyridines of the formula (I) ##STR00001## by adding a secondary and/or aliphatic or mixed aliphatic-aromatic tertiary amine, and mixtures comprising a compound of the formula (I) and a secondary and/or tertiary amine.
7538131 2-{-3-'2-(phenyl)-oxazol-4-ylmethoxymethyl-cyclohexylmethoxy}-propionic acid derivatives useful May 26, 2009
The present invention comprises compounds and compositions for the treatment of metabolic disorders and more particularly, those insulin-related metabolic disorders of the blood such as hyperlipidemia, diabetes, insulin-resistance and the like comprising acetic acid derivatives with
7534591 Bengamide derivatives, process for preparing them, and their use May 19, 2009
The present invention relates to bengamide derivatives which are formed, during fermentation, by the microorganism Myxococcus virescens ST200611 (DSM 15898), to their use for treating cancer diseases, to pharmaceuticals which comprise bengamide derivatives, to a process for preparing
7531663 3-guanidinocarbonyl-1-heteroaryl-indole derivatives, preparation process, their use as medicamen May 12, 2009
The present invention relates to 3-guanidinocarbonyl-1-heteroaryl-indole derivatives, pharmaceutical compositions comprising such derivatives, methods of treatment comprising administering such derivatives, and processes for their preparation.
7531569 Process for preparing (3-oxo-2,3-dihydro-1H-isoindol-1-yl) acetylguanidine derivatives May 12, 2009
A method and apparatus for preventing board warpage during the application and curing or drying of liquid epoxies, or the like, on printed circuit boards using a clamping fixture assembly, which includes at least one clamping fixture support and at least one clamping fixture overlay. If
7528155 Indazole derivatives as inhibitors of hormone sensitive lipase May 5, 2009
The present invention relates to indazole derivatives of the general formulae I or II having the meanings indicated in the description, to the pharmaceutically useful salts thereof and the use thereof as drugs. ##STR00001##
7524887 2-amino-1,3-propanediol compounds for the treatment of acute pain April 28, 2009
The present invention relates to a method for the prophylaxis or treatment of pain using compounds of formula I, ##STR00001## in which R, R2, R3, R4 and R5 have the meanings indicated in the specification.
7514582 2'-substituted 1,1'-biphenyl-2-carboxamides, processes for their preparation, their use as medic April 7, 2009
Compounds of the formula I, ##STR00001## in which R(1), R(2), R(3), R(4), R(5), R(6), R(7), R(8), R(30) and R(31) have the meanings indicated in the claims, are very particularly suitable as novel and antiarrythmic active compounds, in particular for the treatment and prophylaxis of
7514578 Method for producing enantiomeric form of 2,3-diaminopropionic acid derivatives April 7, 2009
The invention relates to a method for producing enantiomeris form of 2, 3-diaminopropionic acid derivatives of formula (I) by asymetric hydrogenation from compounds of formula (II). ##STR00001##
7514423 Use of vasopeptidase inhibitors in the treatment of metabolic diseases, nephropathy and advanced April 7, 2009
The invention discloses and claims the use of vasopeptidase inhibitors of formula (II) ##STR00001## for the treatment of nephropathy in non-diabetic patients.
7514403 Process for the stabilization of proteins in an aqueous solution comprising cysteine in a concen April 7, 2009
The present invention relates to a process for the storage of proteins in an aqueous solution. The addition of cysteine delays the temporal decrease in the effective concentration of the protein. The process is suitable for use in the production of heterologous proteins in microorgan
7501440 Substituted benzoylureidopyridylpiperidine-and-pyrrolidinecarboxylic acid derivatives, processes March 10, 2009
The invention relates to compounds of the formula I ##STR00001## where the radicals are as defined, and their physiologically tolerated salts. The compounds are suitable, for example, as medicaments for preventing and treating type 2 diabetes.
7498341 Heterocyclically substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for thei March 3, 2009
The invention relates to heterocyclically substituted 7-amino-4-quinolone-3-carboxylic acid derivatives and to the physiologically tolerated salts and physiologically functional derivatives thereof.The invention relates to compounds of the formula I ##STR00001## in which the radical
7488829 Diphenylazetidinones, process for their preparation, medicaments comprising these compounds and February 10, 2009
Compounds of the formula I, ##STR00001## in which R1, R2, R3, R4, R5, and R6 have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.
7488818 Method for producing 1,4-diphenyl azetidinone derivatives February 10, 2009
The present invention is directed to the preparation of novel compounds useful in the treatment of hyperlipidemia, arteriosclerosis, hypercholesterolemia, and other related metabolic disorders. More specifically, the present invention is a novel process for the preparation of 1,4-dip
7488746 Substituted thiophenes: compositions, processes of making, and uses in disease treatment and dia February 10, 2009
Substituted thiophenes, processes for their preparation, their use as medicament or diagnostic agent. The substituted thiophene derivatives have the following backbone structure: ##STR00001## Medicaments comprising compounds of this type are of use for preventing or treating various
7482132 Method for determining the activity of ornithine decarboxylase and for identifying effectors of January 27, 2009
The present invention relates to a method for determining the activity of ornithine decarboxylase and for identifying effectors of ornithine decarboxylase activity, to the effectors of ornithine decarboxylase activity, and to the use thereof as pharmaceuticals for the treatment of di
7476652 Acidic insulin preparations having improved stability January 13, 2009
The invention relates to a pharmaceutical formulation comprising a polypeptide selected from the group consisting of insulin, an insulin metabolite, an insulin analog, an insulin derivative and combinations thereof; a surfactant or combinations of two or more surfactants; optionally
7476396 Composition for removing abnormal keratinous material January 13, 2009
The present invention discloses a pharmaceutical method comprising urea, a hydrophilic film-forming agent, water and/or a water-alcohol mixture that is suitable for the removal of abnormal keratinous material.
7470706 Cycloalkyl-substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their prep December 30, 2008
The invention relates to cycloalkyl-substituted 7-amino-4-quinolone-3-carboxylic acid derivatives and to the physiologically tolerated salts and physiologically functional derivatives thereof.The invention relates to compounds of the formula I ##STR00001## in which the radicals have
7465806 Pyrrole-derivatives as factor Xa inhibitors December 16, 2008
The present invention relates to compounds of the formulae I and Ia, ##STR00001## wherein R.sup.0; R.sup.1; R3; R4; R22, Q; V, G and M have the meanings indicated in the claims. The compounds of the formulae I and Ia are valuable pharmacologically active compounds. They exhibit a strong
7462638 Use of I.kappa.B-kinase inhibitors in pain therapy December 9, 2008
The present invention relates to the use of I.kappa.B-kinase Inhibitors and methods for the prophylaxis and therapy for treating pain comprising administering such compounds.
7462613 Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them December 9, 2008
The present invention relates to novel pyridazinone derivatives of the general formula (I) ##STR00001## wherein A is A1 or A2; ##STR00002## R is unsubstituted or at least monosubstituted C.sub.1-C.sub.10-alkyl, aryl, aryl-(C.sub.1-C.sub.10-alkyl)-, heteroaryl, heteroaryl-(C.sub.1-C
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