| Patent Number |
Title Of Patent |
Date Issued |
| RE38797 |
Particle preconcentrator |
September 20, 2005 |
| An apparatus and method for preconcentrating particles and vapors. The preconcentrator apparatus permits detection of highly diluted amounts of particles in a main gas stream, such as a stream of ambient air. A main gas stream having airborne particles entrained therein is passed through |
| 7437766 |
Method and apparatus providing deception and/or altered operation in an information system opera |
October 14, 2008 |
| A method and/or system and/or apparatus providing deception and/or execution alteration in an information system. In specific embodiments, deceptions and/or protections are provided by intercepting and/or modifying operation of one or more system calls of an operating system. |
| 7368290 |
Structural determination of intact proteins using mass spectrometry |
May 6, 2008 |
| The present invention relates to novel methods of determining the sequence and structure of proteins. Specifically, the present invention allows for the analysis of intact proteins within a mass spectrometer. Therefore, preparatory separations need not be performed prior to introducing a |
| 7311882 |
Capillary interconnect device |
December 25, 2007 |
| A manifold for connecting external capillaries to the inlet and/or outlet ports of a microfluidic device for high pressure applications is provided. The fluid connector for coupling at least one fluid conduit to a corresponding port of a substrate that includes: (i) a manifold compri |
| 7310142 |
Fast time-correlated multi-element photon detector and method |
December 18, 2007 |
| Photons emitted from a sample responsive to being excited by laser pulses are directed through a prism onto a photomultiplier tube having several spaced-apart anodes. The prism alters the path of each photon as a function of its wavelength so that the wavelength determines the anode to |
| 7308374 |
Method for siting detectors within a facility |
December 11, 2007 |
| A method, system and article of manufacture of siting one or more detectors in a facility represented with zones are provided. Signals S.sub.i,j representing an effect in zone j in response to a release of contaminant in zone i for one or more flow conditions are provided. A candidat |
| 7296274 |
Method and apparatus providing deception and/or altered execution of logic in an information sys |
November 13, 2007 |
| A method and/or system and/or apparatus providing deception and/or execution alteration in an information system. In specific embodiments, deceptions and/or protections are provided by intercepting and/or modifying operation of one or more system calls of an operating system. |
| 7256667 |
Waveguide device and method for making same |
August 14, 2007 |
| A monolithic micromachined waveguide device or devices with low-loss, high-power handling, and near-optical frequency ranges is set forth. The waveguide and integrated devices are capable of transmitting near-optical frequencies due to optical-quality sidewall roughness. The device or |
| 7225683 |
Composition pulse time-of-flight mass flow sensor |
June 5, 2007 |
| A device for measuring fluid flow rates over a wide range of flow rates (<1 nL/min to >10 .mu.L/min) and at pressures at least as great as 2,000 psi. The invention is particularly adapted for use in microfluidic systems. The device operates by producing compositional variations in |
| 7213473 |
Sample preparation system for microfluidic applications |
May 8, 2007 |
| An apparatus that couples automated injection with flow feedback to provide nanoliter accuracy in controlling microliter volumes. The apparatus comprises generally a source of hydraulic fluid pressure, a fluid isolator joined to the outlet of the hydraulic pressure source and a flow |
| 7204923 |
Continuous flow dielectrophoretic particle concentrator |
April 17, 2007 |
| A continuous-flow filter/concentrator for separating and/or concentrating particles in a fluid is disclosed. The filter is a three-port device an inlet port, an filter port and a concentrate port. The filter separates particles into two streams by the ratio of their dielectrophoretic |
| 7186987 |
Organic materials and devices for detecting ionizing radiation |
March 6, 2007 |
| A .pi.-conjugated organic material for detecting ionizing radiation, and particularly for detecting low energy fission neutrons. The .pi.-conjugated materials comprise a class of organic materials whose members are intrinsic semiconducting materials. Included in this class are .pi.-c |
| 7182371 |
Edge compression manifold apparatus |
February 27, 2007 |
| A manifold for connecting external capillaries to the inlet and/or outlet ports of a microfluidic device for high pressure applications is provided. The fluid connector for coupling at least one fluid conduit to a corresponding port of a substrate that includes: (i) a manifold compri |
| 7162864 |
Method for control of NOx emission from combustors using fuel dilution |
January 16, 2007 |
| A method of controlling NOx emission from combustors. The method involves the controlled addition of a diluent such as nitrogen or water vapor, to a base fuel to reduce the flame temperature, thereby reducing NOx production. At the same time, a gas capable of enhancing flame stability |
| 7161334 |
Modular high voltage power supply for chemical analysis |
January 9, 2007 |
| A high voltage power supply for use in a system such as a microfluidics system, uses a DC--DC converter in parallel with a voltage-controlled resistor. A feedback circuit provides a control signal for the DC--DC converter and voltage-controlled resistor so as to regulate the output v |
| 7151787 |
Backscatter absorption gas imaging systems and light sources therefore |
December 19, 2006 |
| The location of gases that are not visible to the unaided human eye can be determined using tuned light sources that spectroscopically probe the gases and cameras that can provide images corresponding to the absorption of the gases. The present invention is a light source for a backscatt |
| 7128559 |
Programmable imprint lithography template |
October 31, 2006 |
| A template for imprint lithography (IL) that reduces significantly template production costs by allowing the same template to be re-used for several technology generations. The template is composed of an array of spaced-apart moveable and individually addressable rods or plungers. Th |
| 7128046 |
Fuel mixture stratification as a method for improving homogeneous charge compression ignition en |
October 31, 2006 |
| A method for slowing the heat-release rate in homogeneous charge compression ignition ("HCCI") engines that allows operation without excessive knock at higher engine loads than are possible with conventional HCCI. This method comprises injecting a fuel charge in a manner that creates |
| 7124994 |
Silicon micro-mold |
October 24, 2006 |
| The present invention describes a method for rapidly fabricating a robust 3-dimensional silicon-mold for use in preparing complex metal micro-components. The process begins by depositing a conductive metal layer onto one surface of a silicon wafer. A thin photoresist and a standard l |
| 7094326 |
Electrodes for microfluidic applications |
August 22, 2006 |
| An electrode device for high pressure applications. These electrodes, designed to withstand pressure of greater than 10,000 psi, are adapted for use in microfluidic devices that employ electrokinetic or electrophoretic flow. The electrode is composed, generally, of an outer electrica |
| 7090189 |
Compliant cantilevered micromold |
August 15, 2006 |
| A compliant cantilevered three-dimensional micromold is provided. The compliant cantilevered micromold is suitable for use in the replication of cantilevered microparts and greatly simplifies the replication of such cantilevered parts. The compliant cantilevered micromold may be used to |
| 7071595 |
Translation and rotation positioning motor |
July 4, 2006 |
| A positioning device provides the capability of moving an object in both a linear and a rotational direction. The positioning device includes a first piezo stack with plural piezo plates that are capable of movement in orthogonal directions with respect to each other. The positioning |
| 7052608 |
Cast-to-shape electrokinetic trapping medium |
May 30, 2006 |
| A three-dimensional microporous polymer network material, or monolith, cast-to-shape in a microchannel. The polymer monolith, produced by a phase separation process, is capable of trapping and retaining charged protein species from a mixture of charged and uncharged species under the |
| 7030355 |
Low power photomultiplier tube circuit and method therefor |
April 18, 2006 |
| An electrical circuit for a photomultiplier tube (PMT) is disclosed that reduces power consumption to a point where the PMT may be powered for extended periods with a battery. More specifically, the invention concerns a PMT circuit comprising a low leakage switch and a high voltage c |
| 7027150 |
Apparatus for measuring the concentration of a species at a distance |
April 11, 2006 |
| Corrosion of refractory silica brick and air quality issues due to particulate emissions are two important glass manufacturing issues that have been tied to sodium vapor and its transport throughout the melt tank. Knowledge of the relationship between tank operating conditions and ta |
| 7022861 |
Thermally cleavable surfactants |
April 4, 2006 |
| Two new surfactant molecules are reported which contain thermally labile Diels-Alder adducts connecting the polar and non-polar sections of each molecule. The two surfactants possess identical non-polar dodecyl tail segments but exhibit different polar headgroups. The surfactants become |
| 7022381 |
Method for producing high dielectric strength microvalves |
April 4, 2006 |
| A microvalve having a cast-in-place and lithographically shaped mobile, polymer monolith for fluid flow control in microfluidic devices and method of manufacture. The microvalve contains a porous fluorinated polymer monolithic element whose pores are filled with an electrically insul |
| 7022287 |
Single particle electrochemical sensors and methods of utilization |
April 4, 2006 |
| The present invention discloses an electrochemical device for detecting single particles, and methods for using such a device to achieve high sensitivity for detecting particles such as bacteria, viruses, aggregates, immuno-complexes, molecules, or ionic species. The device provides |
| 7019637 |
Systems and methods for detecting and processing |
March 28, 2006 |
| Embodiments of the present invention provides systems and method for detecting. Sensing modules are provided in communication with one or more detectors. In some embodiments, detectors are provided that are sensitive to chemical, biological, or radiological agents. Embodiments of sensing |
| 7012342 |
Low power, scalable multichannel high voltage controller |
March 14, 2006 |
| A low voltage control circuit is provided for individually controlling high voltage power provided over bus lines to a multitude of interconnected loads. An example of a load is a drive for capillary channels in a microfluidic system. Control is distributed from a central high voltag |
| 7008737 |
Gray scale x-ray mask |
March 7, 2006 |
| The present invention describes a method for fabricating an embossing tool or an x-ray mask tool, providing microstructures that smoothly vary in height from point-to-point in etched substrates, i.e., structure which can vary in all three dimensions. The process uses a lithographic t |
| 7005301 |
Piecewise uniform conduction-like flow channels and method therefor |
February 28, 2006 |
| A low-dispersion methodology for designing microfabricated conduction channels for on-chip electrokinetic-based systems is presented. The technique relies on trigonometric relations that apply for ideal electrokinetic flows, allowing faceted channels to be designed on chips using com |
| 7001849 |
Surface treatment and protection method for cadmium zinc telluride crystals |
February 21, 2006 |
| A method for treatment of the surface of a CdZnTe (CZT) crystal that provides a native dielectric coating to reduce surface leakage currents and thereby, improve the resolution of instruments incorporating detectors using CZT crystals. A two step process is disclosed, etching the sur |
| 7001535 |
Polymer formulation for removing hydrogen and liquid water from an enclosed space |
February 21, 2006 |
| This invention describes a solution to the particular problem of liquid water formation in hydrogen getters exposed to quantities of oxygen. Water formation is usually desired because the recombination reaction removes hydrogen without affecting gettering capacity and the oxygen remo |
| 6994826 |
Method and apparatus for controlling cross contamination of microfluid channels |
February 7, 2006 |
| A method for controlling fluid flow at junctions in microchannel systems. Control of fluid flow is accomplished generally by providing increased resistance to electric-field and pressure-driven flow in the form of regions of reduced effective cross-sectional area within the microchan |
| 6988402 |
Mobile monolithic polymer elements for flow control in microfluidic devices |
January 24, 2006 |
| A cast-in-place and lithographically shaped mobile, monolithic polymer element for fluid flow control in microfluidic devices and method of manufacture. Microfluid flow control devices, or microvalves that provide for control of fluid or ionic current flow can be made incorporating a |
| 6975402 |
Tunable light source for use in photoacoustic spectrometers |
December 13, 2005 |
| The present invention provides a photoacoustic spectrometer that is field portable and capable of speciating complex organic molecules in the gas phase. The spectrometer has a tunable light source that has the ability to resolve the fine structure of these molecules over a large waveleng |
| 6969576 |
Photosensitive dissolution inhibitors and resists based on onium salt carboxylates |
November 29, 2005 |
| A photoresist composition that employs onium salt carboxylates as thermally stable dissolution inhibitors. The photoresist composition can be either an onium carboxylate salt with a phenolic photoresist, such as novolac, or an onium cation protected carboxylate-containing resin such as a |
| 6966336 |
Fluid injection microvalve |
November 22, 2005 |
| A microvalve for extracting small volume samples into analytical devices, e.g., high pressure liquid chromatography (HPLC) column, includes: a first body having a first interior surface and two or more outlet ports at the first interior surface that are in fluid communication with two or |
| 6952962 |
Mobile monolithic polymer elements for flow control in microfluidic devices |
October 11, 2005 |
| A cast-in-place and lithographically shaped mobile, monolithic polymer element for fluid flow control in microfluidic devices and method of manufacture. Microfluid flow control devices, or microvalves that provide for control of fluid or ionic current flow can be made incorporating a |
| 6951243 |
Axially tapered and bilayer microchannels for evaporative coolling devices |
October 4, 2005 |
| The invention consists of an evaporative cooling device comprising one or more microchannels whose cross section is axially reduced to control the maximum capillary pressure differential between liquid and vapor phases. In one embodiment, the evaporation channels have a rectangular cross |
| 6926313 |
High pressure capillary connector |
August 9, 2005 |
| A high pressure connector capable of operating at pressures of 40,000 psi or higher is provided. This connector can be employed to position a first fluid-bearing conduit that has a proximal end and a distal end to a second fluid-bearing conduit thereby providing fluid communication betwe |
| 6921630 |
Photoresist substrate having robust adhesion |
July 26, 2005 |
| A substrate material for LIGA applications w hose general composition is Ti/Cu/Ti/SiO.sub.2. The SiO.sub.2 is preferably applied to the Ti/Cu/Ti wafer as a sputtered coating, typically about 100 nm thick. This substrate composition provides improved adhesion for epoxy-based photoresist |
| 6918573 |
Microvalve |
July 19, 2005 |
| A high pressure microvalve for connecting a first fluid-bearing conduit to a second fluid-bearing conduit is provided. The microvalve includes (a) a first body having a first interior surface and at least one port outlet at the first interior surface that is in fluid communication with a |
| 6902827 |
Process for the electrodeposition of low stress nickel-manganese alloys |
June 7, 2005 |
| A process for electrodepositing a low stress nickel-manganese multilayer alloy on an electrically conductive substrate is provided. The process includes the steps of immersing the substrate in an electrodeposition solution containing a nickel salt and a manganese salt and repeatedly |
| 6900952 |
System and method for reproducibly mounting an optical element |
May 31, 2005 |
| The present invention provides a two-piece apparatus for holding and aligning the MEMS deformable mirror. The two-piece apparatus comprises a holding plate for fixedly holding an adaptive optics element in an overall optical system and a base spatially fixed with respect to the optical |
| 6886757 |
Nozzle assembly for HVOF thermal spray system |
May 3, 2005 |
| A nozzle assembly for a HVOF thermal metallic spray coating system includes an inner tube, a middle tube and an outer tube which are concentrically arranged about an axis of the nozzle assembly and are spaced to provide annular, concentric gas flow passages for oxygen and gaseous fuel al |
| 6882786 |
Preform for producing an optical fiber and method therefor |
April 19, 2005 |
| The present invention provides a simple method for fabricating fiber-optic glass preforms having complex refractive index configurations and/or dopant distributions in a radial direction with a high degree of accuracy and precision. The method teaches bundling together a plurality of gla |
| 6869015 |
Tamper-indicating barcode and method |
March 22, 2005 |
| A novel tamper-indicating barcode methodology is disclosed that allows for detection of alteration to the barcode. The tamper-indicating methodology makes use of a tamper-indicating means that may be comprised of a particulate indicator, an optical indicator, a deformable substrate, |
| 6858378 |
Photoimageable composition |
February 22, 2005 |
| The use of photoacid generators including an alkoxyphenylphenyliodonium salt and/or bis(t-butylphenyl)iodonium salt in a photoimageable composition helps improve resolution. Suitable photoimageable compositions includes: (a) a multifuctional polymeric epoxy resin that is dissolved in |
