| Patent Number |
Title Of Patent |
Date Issued |
| 7235552 |
Cholenic acid amides and pharmaceutical compositions thereof |
June 26, 2007 |
| Novel sterol derivatives of formula (I), in which: R.sup.1 represents a hydroxyl group or protected hydroxyl group, R.sup.2 represents a hydrogen atom and a double bond is present at c, or R.sup.1 and R.sup.2 together represent an oxo group and a double bond is present at b or double bon |
| 6967195 |
2-substituted pregna-1-3,5(10) triene and chola-1,3,5(10) triene derivatives and their biologica |
November 22, 2005 |
| Compounds of formula (I) in which: R.sup.1 represents a hydrogen atom or an O-protecting group; R.sup.2 represents a hydroxyl, lower alkoxy, carboxaldehyde, lower alk-1-enyl or hydroxy- or lower alkoxy-substituted lower alkyl group; R.sup.3 represents a methyl group having .alpha.- or |
| 6013814 |
Vitamin D analogues |
January 11, 2000 |
| The present invention relates to novel 1.alpha.-hydroxy vitamin D derivatives in which the 17-position side chain carries an azide or optionally substituted 1,2,3-triazole group, including compounds of general formula (I) where R.sup.1 represents a methyl group having .alpha.- or .be |
| 5872140 |
Vitamin D analogues |
February 16, 1999 |
| The present invention relates to novel 1.alpha.-hydroxy vitamin D derivatives in which the 17-position side chain carries an azide or optionally substituted 1,2,3-triazole group, including compounds of general formula (I) where R.sup.1 represents a methyl group having .alpha.- or .be |
| 5811562 |
Vitamin-D amide derivatives |
September 22, 1998 |
| The present invention relates to compounds of general formula (I) ##STR1## where R.sup.1 and R.sup.2, which may be the same or different, each represent a hydrogen atom or an aliphatic, cycloaliphatic, araliphatic or aryl group or together with the nitrogen atom to which they are att |
| 5786347 |
Vitamin D amine and amide derivatives |
July 28, 1998 |
| The invention relates to vitamin D amine and amide derivatives of general formula ##STR1## where R represents a hydrogen atom, an aliphatic, cycloaliphatic or araliphatic group, or an acyl group comprising an aliphatic, cycloaliphatic, arylaliphatic or aryl group linked to the ni |
| 4772433 |
Vitamin D analogues |
September 20, 1988 |
| Compounds of the general formula ##STR1## wherein R represents a hydrogen atom or a hydroxyl protecting group, Y represents a hydrogen atom or an optionally protected hydroxyl group, X represents the residue of a dienophile and either R.sup.1 represents a halogen atom a hydrocarb |
| 4554105 |
Process for the preparation of 1-hydroxylated vitamin D compounds |
November 19, 1985 |
| 1-unsubstituted 5,6-trans vitamin D compounds are 1.alpha.-hydroxylated by Se.sup.IV oxidation in the presence of selenous acid at a pH in the range 3-9. The oxidation is preferably effected using a 1-unsubstituted-3-trihydrocarbylsilyloxy-5,6-trans vitamin D compound in the presence |
| 4284558 |
Chemical process for fluorinating a tertiary carbon atom in the steroid nucleus |
August 18, 1981 |
| Saturated organic compounds containing a hydrogen atom bound to a tertiary carbon atom may be electrophilically fluorinated by reaction with an electrophilic fluorinating agent such as molecular fluorine or trifluoromethyl hypofluorite under conditions whereby the formation of free f |
| 4263215 |
Process for the preparation of 1-hydroxylated vitamin D compounds |
April 21, 1981 |
| 1-Hydroxy-5,6-trans vitamin D compounds are prepared by oxidizing a 5,6-trans vitamin D compound using a selenic ester which may be formed in situ using selenous acid or selenium dioxide in the presence of an alcohol. |
| 4181655 |
5(3-Substituted aminopropyl)-10-trifluoromethoxy-5H-dibenz[b,f]azepines |
January 1, 1980 |
| Novel compounds of general formula ##STR1## (where R.sup.1 and R.sup.2, which may be the same or different, are hydrogen atoms or alkyl groups; and R.sup.3 and R.sup.4, which may be the same or different, represent alkyl groups which may carry substituents, R.sup.4 alternatively |
| 4064148 |
Chemical process for preparing .DELTA.9(11) dehydrosteroids |
December 20, 1977 |
| The Specification describes a synthetic route for the preparation of a 9,11-dehydro-3-oxygenated 17.alpha.-hydroxy-20-ketopregnane which comprises the steps (i) electrophilically fluorinating a saturated 9,11-unsubstituted 3-oxygenated-17.alpha.-(esterified hydroxy)-20-ketopregnane, |
| 4036864 |
Chemical process |
July 19, 1977 |
| Saturated organic compounds containing a hydrogen atom bound to a tertiary carbon atom may be electrophilically fluorinated by reaction with an electrophilic fluorinating agent such as molecular fluorine or trifluoromethyl hypofluorite under conditions whereby the formation of free f |
| 4011316 |
Cyclohexa-2,5-diene-1-thiones |
March 8, 1977 |
| Compounds of the general formula ##STR1## are provided wherein the substituents R, which may be the same or are different, represent hydrogen atoms or hydrocarbyl groups and the groups R.sup.1 represent hydrocarbyl groups or adjacent pairs of substituents R, or R and R.sup.1 toge |
| 3991103 |
5H Dibenzo (a,d) cycloheptene, 10,11 dihydro, 5(1-halo-3-dimethylaminoprop-1-ylidene) derivative |
November 9, 1976 |
| 11-Halo derivatives of amitriptyline and its analogues, i.e. 5-(1'-halo-3'-aminoprop-1'-yl-idene)-5H-dibenzo[a,d]-10,11-dihydrocyclohep tenes and corresponding 11-oxa analogues as well as the acid addition salts thereof, have notable anti-depressant and tranquillising activity. They a |
| 3930970 |
Photolysis of alcohol nitrites |
January 6, 1976 |
| There is described the preparation of a mononitrate ester of a diol by photolysing in the presence of molecular oxygen a nitrite ester of an alcohol having a hydrogen atom conformationally adjacent to the hydroxy group and in which the atoms joining the hydrogen atom and the hydroxyl |
