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Research Corporation Patents
Assignee:
Research Corporation
Address:
Tucson, AZ
No. of patents:
413
Patents:


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Patent Number Title Of Patent Date Issued
RE32868 Antihyperlipidemic compositions February 14, 1989
The invention concerns cyclic imides, diones, reduced diones and analogs thereof which are useful as antihyperlipidemic agents to reduce serum cholesterol and trigylcerides.
RE31463 Radiopharmaceutical chelates and method of external imaging December 13, 1983
A chelate of technetium-99m, cobalt-57, gallium-67, gallium-68, indium-111 or indium-113m and substituted iminodiacetic acid or an 8-hydroxyquinoline useful as a radiopharmaceutical external imaging agent. The invention also includes preparative methods therefor.
RE30944 Continuous fermentation process and apparatus May 25, 1982
A deep tank reactor is utilized for fermentation of waste liquid or other liquid in a biological reaction resulting in a solid cellular material. The resulting solid material, which is in suspension, is initially separated from the bulk of the liquid by a gaseous flotation process, u
RE30176 Stirling cycle type thermal device December 25, 1979
A Stirling cycle thermal engine or refrigerating device wherein there is no primary mechanical connection between the displacer pistons and their associated power pistons, including various mechanical and pressure fluid means for varying the power output from or the power input to the de
PP6379 Geranium plant "Siren" November 8, 1988
This invention relates to a new distinct cultivar of geranium substantially as illustrated and described characterized as being particularly well adapted to both commercial greenhouse production and garden performance, and possessing unique flavonol and anthocyanin profiles and double fl
PP6378 Geranium plant "Calypso" November 8, 1988
This invention relates to a new distinct cultivar of geranium, substantially as illustrated and described, characterized as being particularly well adapted to both commercial greenhouse production and garden performance, and possessing unique flavonol and anthocyanin profiles, double
PP6219 Geranium plant "Paris" July 12, 1988
This invention relates to a new distinct cultivar of geranium substantially as illustrated and described, characterized as being particularly well adapted to both commercial greenhouse production and garden performance, and possessing unique flavonol and anthocyanin profiles and more ful
PP6218 Geranium plant "Ben Franklin" July 12, 1988
This invention relates to a new distinct cultivar of geranium, substantially as illustrated and described, characterized as being particularly well adapted to both commercial greenhouse production and garden performance, and possessing unique flavonol and anthocyanin profiles and a u
PP5773 Mushroom plant July 22, 1986
A new and distinct variety of mushroom is described. This variety is similar to a type called "smooth white" in the trade. The new variety possesses advantages in both yield and size when compared to three commercially available lines 303, 310 and 348. The new variety also displays a
PP5772 Mushroom plant July 22, 1986
A new and distinct variety of mushroom is described. This variety is similar to a type called "off-white" in the trade. The new variety possesses advantages of both productivity and yield when compared to two commercially available line 348 and Moonlite.TM.. The novel variety also di
PP5187 Asparagus plant January 31, 1984
An asparagus plant having female characteristics, originating from the Mary Washington cultivar, which has been found suitable for use in production of edible spears and of hybrid seed because of its ability to transmit rust resistance, high yield and good field tolerance to root rot as
PP4999 Asparagus Plant No. 22 March 15, 1983
An asparagus plant having particularly valuable male characteristics and suitable for use in production of edible spears and of hybrids since it transmits high yield, rust resistance, and good field tolerance to root rot (Fusarium oxysporum) and crown rot (F. moniliforme) which would
PP4998 Asparagus plant Jersey Centennial March 15, 1983
The variety hereof, is particularly outstanding in its wide geographic adaptation, its ability to produce even in areas infested with Fusarium oxysporum, better than average rust resistance, with a tolerance also to crown rot (F. moniliforme), which is substantially better than comparabl
5099010 Intermediates in the preparation of 3'-amino-2',3'-dideoxycytidine and the pharmacologically acc March 24, 1992
This disclosure describes the preparation of 3'-amino-2', 3'-dideoxyctidine and the pharmacologically acceptable salts thereof which are useful in inhibiting the growth of transplanted tumors in mammals.
5064862 Anticonvulsant method and formulations November 12, 1991
This invention relates to certain aminobenzanilide compounds, and to the use, in the treatment of mammals, of certain aminobenzanilide compounds as anticonvulsant agents.
5023108 Aqueous dispersions of waxes and lipids for pharmaceutical coating June 11, 1991
This invention relates to the coating of pharmaceutically useful solids with an emulsion comprising a wax/lipid, an emulsifying agent and water, which emulsion can be spray dried to form a powder which can subsequently be dispersed in water and coated onto the surface of medicaments to f
4994462 Platelet aggregation inhibitory agents and intermediate therefor February 19, 1991
This invention relates to certain N,N'-bis(nipecotyl)piperazines and their use as platelet aggregation inhibtory agents.
4968619 Modified microorganisms and method of preparing and using same November 6, 1990
Microorganisms have been developed which may be characterized as possessing substantially all of the following qualities or capabilities:(a) capable of having foreign genetic information introduced thereinto and recovered therefrom along with its expression with production of useful gene
4956280 Biphasic shuttle vectors September 11, 1990
This invention provides a biphasic shuttle vector capable replication and expression of foreign genetic information in Escherichia coli and Agmenellum quadruplicatum comprising an E. coli replicon, an A. quadruplicatum replicon, at least two selectable markers and a promoter derived
4925477 Chemical hybridizing agents May 15, 1990
The present invention relates to a method for inducing male sterility in plants which comprises treating seeds of a plant receptive to said treatment by application of an effective amount of a compound of the formula: ##STR1## wherein R and R.sup.1 are hydrogen, alkyl, alkenl, al
4921790 Tumor specific assay for CA125 ovarian cancer antigen May 1, 1990
The present invention relates to a 40 kilodalton subunit of serous cystadinocarcinoma ovarian tumor associated antigen CA125, useful in the diagnosis and monitoring of ovarian cancer. It also relates to an immunoassay method for detection of the antigen in serum for diagnosis and mon
4888170 Vaccines obtained from antigenic gene products of recombinant genes December 19, 1989
This invention relates to a vaccine for the immunization of a vertebrate, comprising:an avirulent derivative of a pathogenic microbe that expresses a recombinant gene derived from a pathogen of said vertebrate it being provided that said avirulent microbe does not normally exchange genet
4866175 Novel process for the synthesis of quinoxaline and benzimidazole-N-oxides September 12, 1989
The synthesis of quinoxaline and benzimidazole-N-oxides and of ester amd amide derivatives of 3-hydroxy-2-quinoxalinecarboxylic acid by a movel process consisting of the reaction between a benzofuroxan and an activated methylene-containing compound under basic conditions.
4863967 N,N-diaminophthalamides September 5, 1989
A compound having the structural formula ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and are hydrogen, C.sub.1 -C.sub.6 alkyl, halogen or C.sub.1 -C.sub.4 alkoxy is disclosed. These compounds demonstrate utility as hypolipidemic agents.The present invention is also
4861721 Bacteria for cellulose digestion August 29, 1989
This invention relates to a process for the microbial degradation of cellulosic material. More specifically, this invention relates to a process for the digestion of cellulose by a microbe capable of carrying out the cellulolytic combined nitrogen.
4857474 Phycoerythrins useful in fluorescent conjugates August 15, 1989
This invention provides a class of phycoerythrins useful in diagnostic and detection protocols wherein a fluorescent label is required. The unique spectral properties of the phycoerythrins described herein provide for increased sensitivity and alternative uses in assays employing them.
4852973 Diffraction free arrangement August 1, 1989
Arrangements are disclosed for generating a well defined traveling wave beam substantially unaffected by diffractive spreading. In different embodiments, the beam can be an electromagnetic wave, particle beam, a transverse beam, a longitudinal beam such as an acoustic beam, or any type
4833294 Inductively coupled helium plasma torch May 23, 1989
An inductively coupled plasma torch including a base member, a plasma tube and a threaded insert member within the plasma tube for directing the plasma gas in a tangential flow pattern. The design of the torch eliminates the need for a separate coolant gas tube. The torch can be read
4829031 Method of preparing ceramic compositions at lower sintering temperatures May 9, 1989
Ceramic oxide diphasic xerogels of structurally dissimilar phases (crystalline and amorphous, semicrystalline or noncrystalline) but compositionally similar phases will be converted to crystalline ceramic oxide products having enhanced densification when subjected to substantially lo
4828799 Therapeutic drug monitoring and analyte determination utilizing micellar chromatography May 9, 1989
A method for the determination of the drug or other analyte content and concentration in bodily fluids that are directly injected in a micellar chromatographic column. Various embodiments of kits are also disclosed.
4828764 N-Fluoro-N-Perfluoromethyl sulfonamides May 9, 1989
N-fluoro-N-perfluoromethyl sulfonamide compounds are provided as fluorinating agents for the fluorination of organic compounds by either the direct electrophilic fluorination of organic compounds or by the fluorination of organic compound carbanions.
4826968 S-alkylated coenzyme A with effect on polyamine acetylase May 2, 1989
The present invention relates to the novel compound N-[2-(S-Coenzyme A) acetyl] sym-norspermidine which electively inhibits the enzyme spermidine/spermine N.sup.1 acetyl transferase thereby aberrating the polyamine biosynthesis pathway. The present compound alone or in combination wi
4820811 Amine reacted therapeutic agents April 11, 1989
A complex of a therapeutic agent is disclosed in which the therapeutic agent is complexed to an ammonium ion selected from the group consisting of ##STR1## where R.sup.1 and R.sup.2 are the same or different and are alkyl or hydroxy substituted alkyl containing 1 to 6 carbon atom
4820706 Pteridine derivatives and method of treating leukemia employing same April 11, 1989
2,4-Diaminopteridine derivatives and the pharmaceutically acceptable salts thereof having potent anticancer activity are disclosed. The derivatives possess the structural formula: ##STR1## wherein Y is NH.sub.2, OH or SH, R is ##STR2## and X is ##STR3## in which R' is
4814612 Method and means for vaporizing liquids for detection or analysis March 21, 1989
This disclosure is concerned with method and apparatus for vaporizing liquid solutions in order to detect, quantitate, and/or determine physical or chemical properties of samples present in liquid solution. Mixtures may be separated by an on-line liquid chromatographic column and the met
4806568 Gossypol derivatives February 21, 1989
This invention relates to a compound of the formula: ##STR1## wherein R.sub.1 is C.tbd.N or COR.sub.3 ; and R.sub.2 is alkyl, alkenyl, alkynyl, or acylwhereinR.sub.3 is hydrogen, alkyl, alkenyl, alkynyl, hydroxy, amino or alkoxyR.sub.4 is hydrogen, alkyl or acyl; andn is the integer 1 or
4798830 Platelet aggregation inhibitory agents and intermediates therefor January 17, 1989
This invention relates to tetrahydroquinoline derivatives and their use for the inhibition of blood platelet aggregation.
4793776 Pump for oscillating a fluid in vivo December 27, 1988
A pump for oscillating a fluid into and out from a body area. The pump forms a fluid chamber for holding the fluid, and comprises a piston for forcing fluid outward from the fluid chamber and into the body, and for drawing fluid inward from the body and into the fluid chamber. A motor is
4790987 Viral glycoprotein subunit vaccine December 13, 1988
The present invention relates to a vaccine composition useful in preparation of virus-caused disease comprising as its active agent at least one immunogenically effective amount of immunogenic viral envelope glycoprotein complexed with a lipid.
4790554 Pulley shift assembly December 13, 1988
An assembly comprising a pulley sub assembly and a shift sub assembly. The pulley sub assembly includes a plurality of pulleys, each pulley includes a plurality of sections, and at least one section of each pulley is axially moveable. The shift sub assembly has a disengaged position to
4784150 Surgical retractor and blood flow monitor November 15, 1988
A surgical retractor instrument which incorporates therein a blood flow monitor. A surgical retractor system is disclosed for manipulation of living tissues and/or organs during diagnostic and/or surgical procedures, providing for the monitoring of the presence or absence of blood flow i
4758596 Method for therapeutic use of methyl tertiary-butyl ether July 19, 1988
Method for dissolving cholesterol calculus in vitro or in vivo comprising contacting the cholesterol calculus with methyl tertiary-butyl ether.
4755167 In vivo method for distribution and stirring of therapeutic agents July 5, 1988
Method and means for distributing therapeutic agents in a localized area of a patient's body comprising introducing a therapeutic area of a patient's body and agitating the therapeutic agent in the localized area of a patient's body by introducing an oscillating liquid to the localized a
4749560 Metal organo phosphorous compounds for NMR analysis June 7, 1988
The present invention relates to a class of compositions and a method for NMR imaging using an NMR signal affecting amount of a paramagnetic, diamagnetic or ferromagnetic metal ion chelated with an organo phosphorous compound.Gadolinium bis(bis-dihydroxyphosphonylmethylphosphinate) is an
4740466 Induction of settlement and metamorphosis in Crassostrea virginica by melanin-synthesizing bacte April 26, 1988
The present invention relates to the discovery of a new bacterium, alteromonas calwellii, which has been found to attract oyster larvae by the production of a compound involved in melanin synthesis. More specifically, the present invention contemplates a method for inducing the settl
4734275 Anti-curare agents March 29, 1988
This invention relates to a method for antagonizing induced the neuromuscular blocking effects of certain therapeutic agents and pathological disorders in mammals, which comprises administering to said mammal an antagonizing-effective amount of a compound of the formula: ##STR1##
4730111 Ion vapor source for mass spectrometry of liquids March 8, 1988
This disclosure is concerned with method and apparatus for vaporizing liquid solutions in order to detect, quantitate, and/or determine physical or chemical properties of samples present in liquid solution. Mixtures may be separated by an on-line liquid chromatographic column and the met
4728328 Cuffed tubular organic prostheses March 1, 1988
A cuffed tubular vascular prosthesis and process for manufacturing the prosthesis are disclosed. A flexible tubular body is formed by coating a glass rod with a polymer solution and air-curing the coating to form a smooth outer surface. The tubular body is removed from the glass rod and
4726854 Cast iron welding electrodes February 23, 1988
Metal filler compositions based on manganese and nickel for the welding of cast iron are disclosed. The filler composition preferably contains about 15 to 50% manganese and 15 to 35% nickel. The filler compositions may be incorporated into a welding rod for Shielded Metal Arc (SMA) or in
4725145 Photodetector arrangement for measuring the state of polarization of light February 16, 1988
An apparatus and method for the measurement of at least one parameter of the state of polarization of a light beam is described. The apparatus includes only a photodetector and no other optical elements. The detector surface is partially specularly reflecting and intercepts the light bea
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