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Regents of the University of California Patents
Assignee:
Regents of the University of California
Address:
Berkeley, CA
No. of patents:
547
Patents:


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Patent Number Title Of Patent Date Issued
6221877 Substituted 4-phthalimidocarboxanilides as inhibitors of purine salvage phosphoribosyltransferas April 24, 2001
The use of certain heterocyclic derivatives for treating parasitic protozoa infections in mammals, in particular bovine trichomoniasis and giardiasis, is disclosed.
6221856 Inositol derivatives for inhibiting superoxide anion production April 24, 2001
Inositol derivatives, compositions comprising inositol derivatives, and methods for using compositions comprising inositol derivatives as agents for inhibiting superoxide anion production are described. The inositol derivatives are obtainable via conventional organic synthesis. The i
6204433 Microinjection methods to transform arthropods with exogenous DNA March 20, 2001
This invention relates to methods for transforming arthropods with exogenous DNA. The methods are useful for arthropods that have not previously been amenable to DNA-mediated transformation, and also provide a simpler and more efficient means of transforming arthropods than have prev
6197541 Recombinant thrombin receptors and assays using them March 6, 2001
The DNA encoding the cell surface receptor for thrombin has been cloned and sequenced. The availability of this DNA permits the recombinant production of thrombin receptor which can be produced at cell surfaces and is useful in assay systems both for the detection of thrombin and for the
6150345 Methods for promoting survival of myelin producing cells November 21, 2000
The present invention provides a method for promoting the survival of myelin producing cells, in particular SCs and oligodendrocytes. Other embodiments of the present invention are directed to therapeutic methods, utilities, and other related uses.
6127123 Cauliflower floral meristem identity genes and methods of using same October 3, 2000
The present invention provides a nucleic acid molecule encoding a CAULIFLOWER (CAL) gene product such as a nucleic acid molecule encoding Arabidopsis thaliana CAL and a nucleic acid molecule encoding Brassica oleracea CAL (BoCAL). The invention also provides a nucleic acid molecule e
6119451 Nitrogen oxide removal using diesel fuel and a catalyst September 19, 2000
Hydrocarbons, such as diesel fuel, are added to internal combustion engine exhaust to reduce exhaust NO.sub.x in the presence of a amphoteric catalyst support material. Exhaust NO.sub.x reduction of at least 50% in the emissions is achieved with the addition of less than 5% fuel as a
6117577 Ambient pressure fuel cell system September 12, 2000
An ambient pressure fuel cell system is provided with a fuel cell stack formed from a plurality of fuel cells having membrane/electrode assemblies (MEAs) that are hydrated with liquid water and bipolar plates with anode and cathode sides for distributing hydrogen fuel gas and water to a
6114044 Method of drying passivated micromachines by dewetting from a liquid-based process September 5, 2000
A method of fabricating a micromachine includes the step of constructing a low surface energy film on the micromachine. The micromachine is then rinsed with a rinse liquid that has a high surface energy, relative to the low surface energy film, to produce a contact angle of greater than
6110740 Human vault RNA August 29, 2000
A polynucleotide encoding a human vault-associated vRNA or its complementary strand. A purified and isolated polynucleotide molecule consisting essentially of a human vault RNA, or its complementary strands, or a combination of a nucleotide sequence consisting essentially of a human
6107102 Therapeutic microdevices and methods of making and using same August 22, 2000
A suspension of microfabricated microdevices for use in therapeutic applications is disclosed. The microdevices have a selected shape, and uniform dimensions preferably in the 100 nm to 10 Am range. Also disclosed are microfabrication methods for making such microdevices.
6096283 Integrated system for the destruction of organics by hydrolysis and oxidation with peroxydisulfa August 1, 2000
An integrated system for destruction of organic waste comprises a hydrolysis step at moderate temperature and pressure, followed by direct chemical oxidation using peroxydisulfate. This system can be used to quantitatively destroy volatile or water-insoluble halogenated organic solve
6090041 vacuum actuated surgical retractor and methods July 18, 2000
A vacuum actuated surgical retractor for retracting body tissue or organs comprises an end-piece adapted for sealing engagement with body tissue, the end-piece having at least one suction port therein, the at least one suction port operably linked to at least one vacuum line. Suction sup
6080423 Three dimensional colorimetric assay assemblies June 27, 2000
A direct assay is described using novel three-dimensional polymeric assemblies which change from a blue to red color when exposed to an analyte, in one case a flu virus. The assemblies are typically in the form of liposomes which can be maintained in a suspension, and show great inte
6077680 ShK toxin compositions and methods of use June 20, 2000
Disclosed are methods and compositions comprising DNA segments, and proteins derived from sea anemone species. More particularly, it concerns the novel ShK toxin, ShK toxin analogs, chemically-modified toxin analogs, and nucleic acid segments encoding the ShK toxin from Stichodactyla
6077510 Borna disease viral sequences, diagnostics and therapeutics for nervous system diseases June 20, 2000
The present invention presents: genomic nucleotide sequence of Borna disease virus, nucleotide and amino acid sequences of Borna disease virus proteins, recombinant viral proteins, vectors and cells containing the sequences or encoding the proteins, ligand binding to these proteins such
6064767 Automatic language identification by stroke geometry analysis May 16, 2000
A computer-implemented process identifies an unknown language used to create a document. A set of training documents is defined in a variety of known languages and formed from a variety of text styles. Black and white electronic pixel images are formed of text material forming the traini
6060656 Si/SiGe superlattice structures for use in thermoelectric devices May 9, 2000
A superlattice structure for use in thermoelectric power generation systems includes m layers of a first one of Silicon and Antimony doped Silicon-Germanium alternating with n layers of Silicon-Germanium which provides a superlattice structure having a thermoelectric figure of merit
6054485 Eye treatments using synthetic thyroid hormone compositions April 25, 2000
The present invention involves the discovery that synthetic thyroid hormones can be used as compositions to reduce intraocular pressure in vivo. Methods of screening synthetic thyroid hormones for effect on intraocular pressure, aqueous pressure, hydraulic conductivity, hyaluronic ac
6052662 Speech processing using maximum likelihood continuity mapping April 18, 2000
Speech processing is obtained that, given a probabilistic mapping between static speech sounds and pseudo-articulator positions, allows sequences of speech sounds to be mapped to smooth sequences of pseudo-articulator positions. In addition, a method for learning a probabilistic mapping
6049380 Single molecule identification using selected fluorescence characteristics April 11, 2000
Single fluorescent molecules in a flowing sample stream are distinguished and identified using only a single laser excitation wavelength. A sample stream is formed containing a dilute mixture of single molecule fluorophores, wherein each one of the fluorophores is serially ordered in
6038388 Anomaly analysis using maximum likelihood continuity mapping March 14, 2000
A method of modeling symbol sequence generation is obtained which allows the probability of symbol sequences to be estimated. The model involves treating symbols as if they are emitted as a point travels through an abstract space called a continuity map (CM), in which each position in th
6037072 Fuel cell with metal screen flow field March 14, 2000
A polymer electrolyte membrane (PEM) fuel cell is provided with electrodes supplied with a reactant on each side of a catalyzed membrane assembly (CMA). The fuel cell includes a metal mesh defining a rectangular flow-field pattern having an inlet at a first corner and an outlet at a
6037016 Capacitively coupled RF diamond-like-carbon reactor March 14, 2000
A process of coating a non-conductive fiber with diamond-like carbon, including passing a non-conductive fiber between a pair of parallel metal grids within a reaction chamber, introducing a hydrocarbon gas into the reaction chamber, forming a plasma within the reaction chamber for a
6032464 Traveling-wave device with mass flux suppression March 7, 2000
A traveling-wave device is provided with the conventional moving pistons eliminated. Acoustic energy circulates in a direction through a fluid within a torus. A side branch may be connected to the torus for transferring acoustic energy into or out of the torus. A regenerator is locat
6029079 Evaluated teletherapy source library February 22, 2000
The Evaluated Teletherapy Source Library (ETSL) is a system of hardware and software that provides for maintenance of a library of useful phase space descriptions (PSDs) of teletherapy sources used in radiation therapy for cancer treatment. The PSDs are designed to be used by PEREGRINE,
6015599 High vertical aspect ratio thin film structures January 18, 2000
This invention relates to the area of microelectromechanical systems in which electronic circuits and mechanical devices are integrated on the same silicon chip. The method taught herein allows the fabrication of thin film structures in excess of 150 microns in height using thin film
6014387 Stable operating regime for traveling wave devices January 11, 2000
Autophase stability is provided for a traveling wave device (TWD) electron beam for amplifying an RF electromagnetic wave in walls defining a waveguide for said electromagnetic wave. An off-axis electron beam is generated at a selected energy and has an energy noise inherently arising
6004927 Method for increasing bioavailability of orally administered pharmaceutical compounds December 21, 1999
A method for increasing bioavailability of an orally administered hydrophobic pharmaceutical compound, which comprises orally administering the pharmaceutical compound to a mammal in need of treatment with the compound concurrently with a bioenhancer comprising an inhibitor of a cyto
6003276 Reinforcement of cementitious walls to resist seismic forces December 21, 1999
A cementitious wall is externally reinforced against out-of-plane or in-plane seismic forces using an overlying layer of composite material, preferably a carbon-fiber/polymer matrix composite material. To externally reinforce the wall against out-of-plane forces, the composite material i
6001060 Video data representation of physiological data December 14, 1999
A system for patient diagnostic testing includes the physiological data output is in a two dimensional graphical format. Optionally, the report includes imaging data. Color is a dimension provided to the graphical presentation of normal patient data in horizontal and vertical dimensions.
5994372 Peripherally active anti-hyperalgesic opiates November 30, 1999
Compositions and methods using the compositions for treatment of peripheral hyperalgesia are provided. The compositions contain an anti-hyperalgesia effective amount of one or more compounds that directly or indirectly interact with peripheral opiate receptors, but that do not, upon topi
5994346 Use of exochelins in the preservation of organs for transplant November 30, 1999
Exochelins can be used to prevent damage to organs for transplant from the formation or presence of the .circle-solid.OH radical. In particular, the invention is directed to the administration of exochelins to the organ prior to or coincidental with removal from a donor, storage, implant
5991019 Method and apparatus for bubble chamber spectroscopy November 23, 1999
A bubble chamber spectrometer provides a new method for the sensitive detection of an analyte in a solvent. A bubble chamber receives a solution containing an analyte to be detected. A laser is adapted to direct an output laser beam through the bubble chamber, where the laser is selected
5990479 Organo Luminescent semiconductor nanocrystal probes for biological applications and process for November 23, 1999
A luminescent semiconductor nanocrystal compound is described which is capable of linking to an affinity molecule. The compound comprises (1) a semiconductor nanocrystal capable of emitting electromagnetic radiation (luminescing) in a narrow wavelength band and/or absorbing energy, and/o
5985328 Micromachined porous membranes with bulk support November 16, 1999
A microfabricated containment capsule has a bulk substrate delimiting a cavity with a boundary, a first portion of which constitutes an inner wall of a solid portion of the bulk substrate. The bulk substrate also provides at a second portion of the boundary a membrane joined to one side
5985164 Method for forming a filter November 16, 1999
Surface micromachining and bulk micromachining are employed for realizing a porous membrane with bulk support for a microparticle filter. The filter is manufactured by a process employing a thin film etch-stop, in which the bulk substrate is etched using a first etching process followed
5981827 Carbon based prosthetic devices November 9, 1999
A composite article is disclosed including a porous structural member formed of carbon fiber, the porous structural member containing a multiplicity of pores of dimensions greater than about 200 microns in diameter, the porous structural member further including carbon fill material
5981236 Geminivirus-based gene expression system November 9, 1999
A geminivirus based vector system for obtaining controlled expression of a nucleic acid fragment of interest is disclosed. Tissue specific regulatory regions are identified employing cDNA screening and the resulting tissue-specific regulatory regions are manipulated for use in geminiviru
5973826 Reflective optical imaging system with balanced distortion October 26, 1999
An optical system compatible with short wavelength (extreme ultraviolet) An optical system compatible with short wavelength (extreme ultraviolet) radiation comprising four reflective elements for projecting a mask image onto a substrate. The four optical elements comprise, in order from
5971565 Lamp system with conditioned water coolant and diffuse reflector of polytetrafluorethylene(PTFE) October 26, 1999
A lamp system with a very soft high-intensity output is provided over a large area by water cooling a long-arc lamp inside a diffuse reflector of polytetrafluorethylene (PTFE) and titanium dioxide (TiO.sub.2) white pigment. The water is kept clean and pure by a one micron particulate
5958605 Passivating overcoat bilayer for multilayer reflective coatings for extreme ultraviolet lithogra September 28, 1999
A passivating overcoat bilayer is used for multilayer reflective coatings for extreme ultraviolet (EUV) or soft x-ray applications to prevent oxidation and corrosion of the multilayer coating, thereby improving the EUV optical performance. The overcoat bilayer comprises a layer of silico
5958299 Explosive simulants for testing explosive detection systems September 28, 1999
Explosives simulants that include non-explosive components are disclosed that facilitate testing of equipment designed to remotely detect explosives. The simulants are non-explosive, non-hazardous materials that can be safely handled without any significant precautions. The simulants
5955365 Self-assembling polynucleotide delivery system September 21, 1999
This invention provides a self-assembling polynucleotide delivery system comprising components aiding in the delivery of the polynucleotide to the desired address which are associated via noncovalent interactions with the polynucleotide. The components of this system include DNA-masking
5952119 Fuel cell membrane humidification September 14, 1999
A polymer electrolyte membrane fuel cell assembly has an anode side and a cathode side separated by the membrane and generating electrical current by electrochemical reactions between a fuel gas and an oxidant. The anode side comprises a hydrophobic gas diffusion backing contacting one s
5943150 Massively parallel processor networks with optical express channels August 24, 1999
An optical method for separating and routing local and express channel data comprises interconnecting the nodes in a network with fiber optic cables. A single fiber optic cable carries both express channel traffic and local channel traffic, e.g., in a massively parallel processor (MPP) n
5939318 Cholesterol disposal fusion enzymes August 17, 1999
Fusion enzymes having multiple segments of different biological activity including one segment having P450scc activity and at least one segment having electron-transfer activity for transferring electrons to P450scc are described along with genetic constructs for production of such enzym
5919364 Microfabricated filter and shell constructed with a permeable membrane July 6, 1999
Microfabricated filters constructed with permeable polysilicon membranes and methods for fabricating such filters. The filters include a frame structure having a plurality of openings therethrough and a permeable polysilicon membrane disposed over the openings in the frame structure.
5919350 Mediated electrochemical oxidation of organic wastes using a Co(III) mediator in a neutral elect July 6, 1999
An electrochemical cell with a Co(III) mediator and neutral pH anolyte provides efficient destruction of organic and mixed wastes. The organic waste is concentrated in the anolyte reservoir, where the cobalt mediator oxidizes the organics and insoluble radioactive species and is regenera
5914097 Amino-acyl-type and catecholamine-type contrast agents for MRI June 22, 1999
The present invention relates to the preparation of amino-acyl-type and catecholamine-type compounds having multiple carboxylic acid functional groups. Paramagnetic metal (II) or (III) ion chelate complexes are formed using these compounds for use as intravenous contrast agents to produc
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