| Patent Number |
Title Of Patent |
Date Issued |
| 7109394 |
Methods for modulating floral organ identity, modulating floral organ number, increasing of meri |
September 19, 2006 |
| This invention is directed to plant genetic engineering. In particular, it relates to DEMETER (DMT) nucleic acids and polypeptides that control, for example, seed (and in particular endosperm, embryo and seed coat) development, flowering time, chromosomal DNA methylation and transcri |
| 7101981 |
Bovine growth hormone recombinantly produced in E. coli |
September 5, 2006 |
| Recombinant materials have been obtained which permit the production of bovine growth hormone in E. coli. |
| 7084208 |
N-halamine vinyl compounds and their polymeric biocides |
August 1, 2006 |
| The present invention provides heterocyclic vinylic compounds that can be used to form biocidal polymers. The polymers thus generated can used alone or can be grafted onto textiles, fabrics and polymers. The polymers are readily converted to N-halamine structures on exposure to a halogen |
| 7083961 |
Crystal structures of T. foetus inosine monophosphate dehydrogenase in complex with substrate, c |
August 1, 2006 |
| The invention provides a crystalline complex containing T. foetus IMPDH in complex with inosine monophosphate (IMP), the complex specified by disclosed atomic coordinates. Also provided are crystalline complexes of containing T. foetus IMPDH with both inosine monophosphate (IMP) and |
| 7070771 |
Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells |
July 4, 2006 |
| This invention relates to genes which encode accessory molecule ligands, such as the CD40 ligand and their use for immunomodulation, vaccination and treatments of various human diseases, including malignancies and autoimmune diseases. This invention also describes the use of accessory |
| 7057435 |
Distributed delay-locked-based clock and data recovery systems |
June 6, 2006 |
| A clock and data recovery system using a distributed variable delay line is provided. The clock and data recovery system can use a delay-locked loop methodology to align a local clock with an incoming data stream. The variable delay line can include a transmission line coupled with a |
| 7057073 |
Synthesis of trinitrophloroglucinol and triaminotrinitrobenzene (TATB) |
June 6, 2006 |
| A method to convert surplus nitroarene explosives into trinitrophloroglucinol and triaminotrinitrobenzene (TATB) is described. Picric acid is directly aminated to diaminopicric acid, which is converted to trinitrophloroglucinol and triaminotrinitrobenzene. |
| 7041462 |
Conformational and topological protein regulation |
May 9, 2006 |
| Methods and compositions are provided for identifying novel conformers of proteins not known to exist as different conformers. By using chimeric genes replacing a native signal sequence with a different signal sequence resulting in the production of a conformer, one can compare the nativ |
| 7026155 |
Method of reducing bacterial proliferation |
April 11, 2006 |
| Bacteria and in particular pathogenic bacteria are treated in a manner which alters the bacteria's native level or activity of DNA methyltransferase (Dam). The alteration results in a change in the bacteria's native level of methylation of adenine in a GATC tetranucleotide which inhi |
| 7015646 |
Magnetic and electrostatic confinement of plasma with tuning of electrostatic field |
March 21, 2006 |
| A system and method for containing plasma and forming a Field Reversed Configuration (FRC) magnetic topology are described in which plasma ions are contained magnetically in stable, non-adiabatic orbits in the FRC. Further, the electrons are contained electrostatically in a deep energy |
| 7005411 |
Method for modulating nerve cell function |
February 28, 2006 |
| The amount of active Robo expressed on a cell is modified by modulating the effective amount of a Comm polypeptide in contact with the cell, whereby the amount of expressed active Robo is modulated inversely with the modulation of the effective amount of the Comm polypeptide in contact |
| 6992915 |
Self reverse bias low-power high-performance storage circuitry and related methods |
January 31, 2006 |
| An integrated circuit is provided comprising a first NMOS transistor; a first PMOS transistor; a second NMOS transistor; a second PMOS transistor; a first bias voltage node coupled to a first source/drain of the first NMOS transistor; a second bias voltage node coupled to a first sou |
| 6974896 |
Trace element phytoremediation |
December 13, 2005 |
| The invention provides methods and compositions for trace element, particularly heavy metal phytoremediation, including plants which are genetically engineered to overexpress a sulfate assimilation pathway enzyme gene and thereby provide enhanced trace element accumulation. In variou |
| 6960448 |
Methods for diabetes susceptibility assessment in asymptomatic patients |
November 1, 2005 |
| Assays for identifying human patients at risk for developing insulin-dependent diabetes mellitus rely on detection of autoantibodies to a 38 kD autoantigen present in pancreatic .beta.-cells in patient sera. It has been found that autoantibodies to this particular autoantigen develop |
| 6952436 |
Inorganic/block copolymer-dye composites and dye doped mesoporous materials for optical and sens |
October 4, 2005 |
| A method for preparing transparent mesostructured inorganic/block-copolymer composites or inorganic porous solids containing optically responsive species with selective optical, optoelectronic, and sensing properties resulting therefrom. Mesoscopically organized inorganic/block copolymer |
| 6946257 |
Patched genes and uses related thereto |
September 20, 2005 |
| Methods are provided for identifying agents that decrease hedgehog signal transduction for ameliorating an effect of loss of function of a patched gene in a mammalian cell. |
| 6908918 |
Antitumor agents |
June 21, 2005 |
| The present invention provides compounds of general formula I or II: ##STR1##wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, and R.sub.7 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, as well as pharmaceutical composition |
| 6897357 |
Characterization of phenylalanine ammonia-lyase (PAL) gene in wounded lettuce tissue |
May 24, 2005 |
| The invention provides phenylalanine ammonia-lyase (PAL) sequences, and constructs and methods related thereto. In one aspect, Lactuca sativa PAL sequences are isolated and characterized. The invention also provides novel sequences associated with PAL polynucleotide sequences and methods |
| 6884589 |
Model for myeloid cell growth, differentiation and disease |
April 26, 2005 |
| The invention is a genetic construct comprising the coding sequence for a hormone dependent E2a-Pbx1 protein. The invention is the use of the construct to generate hematopoietic cell lines arrested in differentiation upon exposure to the appropriate hormone. Upon removal of the hormone, |
| 6872750 |
Modulating angiogenesis |
March 29, 2005 |
| The invention provides methods and compositions relating to Kuz involvement in angiogenesis. In various embodiments, the invention provides methods for modulating angiogenesis by specifically modulating the activity of Kuz in a vertebrate animal predetermined to have a pathogenic angioge |
| 6872537 |
Assays for the detection of microtubule depolymerization inhibitors |
March 29, 2005 |
| This invention provides methods for the screening and identification of agents having potent effects on the progression of the cell cycle. In one embodiment, the methods involve contacting a polymerized microtubule with a microtubule severing protein or a microtubule depolymerizing prote |
| 6852321 |
Lectin-derived progenitor cell preservation factor and methods of use |
February 8, 2005 |
| The invention relates to an isolated nucleic acid molecule that encodes a protein that is effective to preserve progenitor cells, such as hematopoietic progenitor cells. The nucleic acid comprises a sequence defined by SEQ ID NO:1, a homolog thereof, or a fragment thereof. The encode |
| 6831070 |
Delivery of therapeutic gene products by intestinal cell expression |
December 14, 2004 |
| The present invention provides methods of delivering a secreted protein into the bloodstream of a mammal. A nucleic acid molecule encoding the protein is introduced into the gastrointestinal tract of the mammal, and the nucleic acid molecule enters an intestinal epithelial cell, where th |
| 6828477 |
Method of enhancing endosperm development in a plant |
December 7, 2004 |
| The invention provides methods of controlling endosperm development in plants. |
| 6827935 |
Method of and compositions for immunization with the pseudomonas V antigen |
December 7, 2004 |
| A method of inhibiting, moderating or diagnosing Pseudomonas aeruginosa infection is disclosed. In one embodiment, this method comprises inoculating a patient with an effective amount of PcrV antigen. |
| 6824266 |
Lenses capable of post-fabrication power modification |
November 30, 2004 |
| The present invention relates to lenses that are capable of post-fabrication power modifications. In general, the inventive lenses comprise (i) a first polymer matrix and (ii) a refraction modulating composition that is capable of stimulus-induced polymerization dispersed therein. Wh |
| 6821742 |
Conformational and topological protein regulation |
November 23, 2004 |
| Methods and compositions are provided for identifying novel conformers of proteins not known to exist as different conformers. By using chimeric genes replacing a native signal sequence with a different signal sequence resulting in the production of a conformer, one can compare the nativ |
| 6821487 |
Method and apparatus for preparing lipidic mesophase material |
November 23, 2004 |
| A coupling system can utilize a first receptacle and a second receptacle to couple syringes together. Syringes can be used to mix viscous material and/or dispense the viscous material. Furthermore, a kit can be provided that contains parts used in mixing and/or dispensing viscous materia |
| 6819692 |
Optical amplifiers and lasers |
November 16, 2004 |
| An optical amplifier and laser having both broad band and wide range specific band capability can be based on semiconductor nanocrystal solids. |
| 6815431 |
Methods for therapy of neurodegenerative disease of the brain |
November 9, 2004 |
| A specific clinical protocol for use toward therapy of defective, diseased and damaged neurons in the mammalian brain, of particular usefulness for treatment of neurodegenerative conditions such as Parkinson's disease and Alzheimer's disease. The protocol is practiced by directly deliver |
| 6800793 |
Geminivirus resistant transgenic plants |
October 5, 2004 |
| Transgenic plants with increased resistance to geminivirus infection, and nucleic acid constructs useful in producing such plants, are described. The transgenic plants express a mutant AL1/C1 geminivirus protein, which increases resistance to infection by at least one geminivirus, compar |
| 6790615 |
Methods and compositions for regulating cell cycle progression |
September 14, 2004 |
| Method and compositions for regulating cell cycle progression are disclosed. Compositions include nucleic acids comprising a human Cdc5 gene, antisense gene and fragments thereof and a human Cdc5 protein and polypeptide fragments thereof polypeptide. The consensus DNA binding site fo |
| 6770273 |
Vaccine based on attenuated Haemophilus somnus |
August 3, 2004 |
| The present invention provides a method for protecting cattle from diseases such as septicemia, pneumonia or abortion by immunizing them with an H. somnus vaccine. Provided are natural isolates of H. somnus strains that have one or more important features of such vaccine, including, |
| 6756036 |
Methods for treating cancer using PSCA antibodies and fragments thereof |
June 29, 2004 |
| The invention provides a novel prostate cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent |
| 6734000 |
Nanoporous silicon support containing macropores for use as a bioreactor |
May 11, 2004 |
| A nanoporous silicon support comprising a plurality of macropores is provided to function as a bioreactor for the maintenance of cells in culture in a differentiated state. Each cell or group of cells is grown in an individual macropore and is provided with nutrients such as by perfu |
| 6727407 |
NUCLEIC ACIDS ENCODING THE ARABIDOPSIS PROTEIN KINASE .beta.-SUBUNIT CKB3 AND A METHOD OF ALTERI |
April 27, 2004 |
| A gene designated CKB3 whose product interacts specifically with CCA1 has been identified through use of the yeast two-hybrid system. CKB3 is a structural and functional homologue of the regulatory (.beta.) subunit of protein kinase CK2 in Arabidopsis. Recombinant CK2 can phosphorylate C |
| 6721587 |
Membrane and electrode structure for implantable sensor |
April 13, 2004 |
| The invention is the design of a biological measuring device for the determination of the concentration of biomolecules (e.g. glucose) in an environment which is designed for implantation into an individual or for use in the context of an external apparatus. The device contains a com |
| 6693130 |
Inhibitors of epoxide hydrolases for the treatment of hypertension |
February 17, 2004 |
| The invention provides compounds that inhibit epoxide hydrolase in therapeutic applications for treating hypertension. A preferred class of compounds for practicing the invention have the structure shown by ##STR1##wherein R is alkyl or aryl, the compound is trans-across the epoxide ring |
| 6692509 |
Method of using a clot capture coil |
February 17, 2004 |
| A clot and foreign body removal device is described which comprises a catheter with at least one lumen. Located within the catheter is a clot capture coil that is connected to an insertion mandrel. In one embodiment, the clot capture coil is made out of a solid elastic or superelastic |
| 6686334 |
Use of inhibitors of protein kinase C epsilon to treat pain |
February 3, 2004 |
| The role of the .epsilon. isozyme of protein kinase C ("PKC.epsilon.") in pain perception, particularly hyperalgesia, methods of lessening pain through administration of inhibitors of PKC.epsilon., methods of identifying compounds that modulate pain, and pharmaceutical compositions c |
| 6683058 |
Methods for therapy of neurodegenerative disease of the brain |
January 27, 2004 |
| A specific clinical protocol for use toward therapy of defective, diseased and damaged cholinergic neurons in the mammalian brain, of particular usefulness for treatment of neurodegenerative conditions such as Alzheimer's disease. The protocol is practiced by delivering a definite co |
| 6673561 |
Diagnostic test for thrombotic or thromboembolic disease |
January 6, 2004 |
| Thrombotic or thromboembolic disease is detected or monitored by determining the presence or amount B in a urine sample. |
| 6663886 |
Inhibition of cell-cell binding by lipid assemblies |
December 16, 2003 |
| This invention relates generally to the field of therapeutic compounds designed to interfere between the binding of ligands and their receptors on cell surface. More specifically, it provides products and methods for inhibiting cell migration and activation using lipid assemblies with |
| 6660995 |
Particle size analysis in a turbid media with a single-fiber, optical probe while using a visibl |
December 9, 2003 |
| Apparatus and method for measuring scatterer size in a dense media with only a single fiber for both light delivery and collection are disclosed. White light is used as a source and oscillations of the detected light intensities are measured as a function of wavelength. The maximum and |
| 6660484 |
Colorimetric glycopolythiophene biosensors |
December 9, 2003 |
| The present invention relates to methods and compositions for the direct detection of analytes using observable spectral changes in biopolymeric systems. In particular, the present invention allows for the direct colorimetric detection of analytes using color changes that occur in gl |
| 6654445 |
Device and method for determining proportions of body materials |
November 25, 2003 |
| The present invention provides a radiation device that includes a device for retaining therein the body part in a uniform position. In addition, at least two reference materials that have attenuation characteristics are used and retained in the retaining device. The reference materials a |
| 6636145 |
Vehicle sharing system and method with parking state detection |
October 21, 2003 |
| A shared vehicle system includes a central facility, at least one vehicle distribution port facility and a plurality or fleet of vehicles, each having a vehicle subsystem. In general, the central station and port facility and the vehicle subsystems communicate in a manner to allow a |
| 6635803 |
Method to improve drought tolerance in plants |
October 21, 2003 |
| A method to increase drought resistance in plants is provided. The method comprises inhibiting or disabling inward-rectifying K.sup.+ (K.sup.+.sub.in) channels in the stomatal guard cells of the plant. |
| 6630618 |
Transgenic plants having non-pathogen induced systemic acquired resistance (SAR) |
October 7, 2003 |
| The present invention discloses the production of transgenic plants that exhibit a systemic acquired resistance (SAR) response even in the absence of an infecting pathogen. The transgenic plants are produced by a method comprising obtaining a plant having a first nucleic acid molecule en |
| 6630197 |
Inhibition of sulfate-reducing-bacteria-mediated degradation using bacteria which secrete antimi |
October 7, 2003 |
| The present invention relates to the field of degradation or corrosion prevention or inhibition through the use of bacteria which secrete antimicrobial chemical compositions. In particular, the invention relates to the use of bacteria which, either naturally or through the use of rec |
