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Population Genetics Technologies Ltd Patents
Assignee:
Population Genetics Technologies Ltd
Address:
Cambridge, GB
No. of patents:
14
Patents:












Patent Number Title Of Patent Date Issued
8563274 Compositions and methods for intramolecular nucleic acid rearrangement October 22, 2013
Aspects of the present invention are drawn to processes for moving a region of interest in a polynucleotide from a first position to a second position with regard to a domain within the polynucleotide, also referred to as a "reflex method". In certain embodiments, the reflex method r
8298767 Compositions and methods for intramolecular nucleic acid rearrangement October 30, 2012
Aspects of the present invention are drawn to processes for moving a region of interest in a polynucleotide from a first position to a second position with regard to a domain within the polynucleotide, also referred to as a "reflex method". In certain embodiments, the reflex method r
8288097 Asymmetric adapter library construction October 16, 2012
The present invention provides methods and compositions for asymmetrically tagging a nucleic acid fragment using asymmetric adapters.
8241850 Methods and compositions for isolating nucleic acid sequence variants August 14, 2012
The invention is drawn to isolating sequence variants of a genetic locus of interest using a modified iterative primer extension method. The nucleic acids analyzed are generally single stranded and have a reference sequence which is used as a basis for performing iterative single nuc
8168385 Methods and compositions for tagging and identifying polynucleotides May 1, 2012
The invention provides methods and compositions for attaching oligonucleotide tags to polynucleotides for the purpose of carrying out analytical assays in parallel and for decoding the oligonucleotide tags of polynucleotides selected in such assays. Words, or subunits, of oligonucleo
8148068 Methods and compositions for tagging and identifying polynucleotides April 3, 2012
The invention provides methods and compositions for attaching oligonucleotide tags to polynucleotides for the purpose of carrying out analytical assays in parallel and for decoding the oligonucleotide tags of polynucleotides selected in such assays. Words, or subunits, of oligonucleo
8124336 Methods and compositions for reducing the complexity of a nucleic acid sample February 28, 2012
Aspects of the present invention are drawn to methods and compositions for sorting nucleic acid molecules into physically separate compartments according to the identity of a nucleotide base or sequence of bases at a specific location, resulting in the production of reduced complexity
8029993 Asymmetric adapter library construction October 4, 2011
The present invention provides methods and compositions for asymmetrically tagging a nucleic acid fragment using asymmetric adapters.
8021842 Nucleic acid analysis using sequence tokens September 20, 2011
The present invention provides methods and compositions for tagging nucleic acid sequence fragments, e.g., a set of nucleic acid sequence fragments from a single genome, with one or more unique members of a collection of oligonucleotide tags, or sequence tokens, which, in turn, can b
7635566 Methods and compositions for isolating nucleic acid sequence variants December 22, 2009
The invention is drawn to isolating sequence variants of a genetic locus of interest using a modified iterative primer extension method. The nucleic acids analyzed are generally single stranded and have a reference sequence which is used as a basis for performing iterative single nuc
7579153 Isothermal DNA amplification August 25, 2009
The present invention provides for amplification of one or more polynucleotides by multi-staged linear amplifications using one or more RNA polymerases. At each stage RNA transcripts are accumulated at a linear rate, so that multiple stages provide for faster than linear transcript a
7544473 Nucleic acid analysis using sequence tokens June 9, 2009
The present invention provides methods and compositions for tagging nucleic acid sequence fragments, e.g., a set of nucleic acid sequence fragments from a single genome, with one or more unique members of a collection of oligonucleotide tags, or sequence tokens, which, in turn, can b
7537897 Molecular counting May 26, 2009
The invention provides methods and compositions for counting molecules in a sample, wherein each molecule is labeled with a unique oligonucleotide tag. Such tags are amplified and identified rather than the molecules themselves; that is, the problem of counting molecules is converted int
7393665 Methods and compositions for tagging and identifying polynucleotides July 1, 2008
The invention provides methods and compositions for attaching oligonucleotide tags to polynucleotides for the purpose of carrying out analytical assays in parallel and for decoding the oligonucleotide tags of polynucleotides selected in such assays. Words, or subunits, of oligonucleo

 
 
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