| Patent Number |
Title Of Patent |
Date Issued |
| 6319678 |
Process for glucuronidation screening |
November 20, 2001 |
| A process used to identify activity of conjugative enzymes involved in xenobiotic transformations, such as glucuronosyltransferases. |
| 5891696 |
Compositions for cytochrome P450 biotransformation reactions |
April 6, 1999 |
| A storable biotransformation mixture that can oxidize a drug, comprising a cytochrome P450 enzyme, an electron donor; and, a buffer solution. In a preferred embodiment the mixture also contains liposomes, cytochrome b.sub.5 and NADPH-P450 reductase as the electron donor. The mixture is |
| 5824557 |
Method for detecting and quantitating nucleic acid impurities in biochemical preparations |
October 20, 1998 |
| A homogeneous fluorescence-based nucleic acid detection and quantitation system is provided to measure nucleic acid in protein solutions. The process relies on the intercalation of a non-fluorescent dye into a double-stranded nucleic acid helix or single-stranded nucleic acid. The dy |
| 5786139 |
Method and kit for detecting nucleic acid cleavage utilizing a covalently attached fluorescent t |
July 28, 1998 |
| The present invention is based on the degradation of a fluorescence labeled nucleic acid such as DNA (F-DNA), RNA (F-RNA) or DNA/RNA substrate. The label may be covalently attached to the relatively high volume substrate at one position or many positions. The nucleic acid is then put in |