| Patent Number |
Title Of Patent |
Date Issued |
| D450240 |
Nested package |
November 13, 2001 |
|
| 7448264 |
Non-destructive method for evaluating the strength of cancellous bone |
November 11, 2008 |
| A non-destructive method for evaluating the strength of cancellous bone includes the steps of performing at least two of the following tests on each cancellous bone of a population of cancellous bones: a manual compression test, an apparent density test, and an appearance test; deter |
| 7413576 |
Biocompatible osteogenic band for repair of spinal disorders |
August 19, 2008 |
| Methods of repairing a joint formed by at least two bone sections are provided wherein a biocompatible osteogenic band fabricated from an osteogenic biological material such as bone, tendon, ligament and collagen is affixed to two or more bone sections. |
| 7399739 |
Vertebral augmentation composition and method |
July 15, 2008 |
| A flowable vertebral augmentation composition for the treatment and repair of a vertebral body defect, e.g., an osteoporotic condition, contains biocompatible, optionally osteoconductive, support elements that are resistant to deformation or fracture under the normal physiologic loads |
| 7357895 |
Method for sterilizing bioactive materials |
April 15, 2008 |
| A method is provided for sterilizing a bioactive material which comprises contacting the bioactive material with hydrogen gas and while the bioactive material is in contact with hydrogen gas, irradiating the bioactive material with ionizing radiation to sterilize the material. |
| 7323193 |
Method of making demineralized bone particles |
January 29, 2008 |
| Demineralized bone particles are obtained by demineralizing whole bone and thereafter subdividing the demineralized bone to provide the demineralized bone particles. |
| 7291345 |
Formable and settable polymer bone composite and method of production thereof |
November 6, 2007 |
| A composite osteoimplant. The osteoimplant includes a polymer and bone-derived particles. The composite is adapted and constructed to be formable during or immediately prior to implantation and to be set after final surgical placement. |
| 7270813 |
Coupling agents for orthopedic biomaterials |
September 18, 2007 |
| The invention provides a method for the preparation of bone-polymer composites wherein the mineral portion of the bone is treated with a coupling agent before being incorporated into a biocompatible polymeric matrix. The resulting composites may be used as such or be further processe |
| 7179299 |
Osteoimplant and method for making same |
February 20, 2007 |
| A method of manufacturing an osteoinductive osteoimplant is provided which comprises the steps of: demineralizing part or all of at least one surface of a monolithic section of cortical bone to a depth of at least about 100 microns; and, configuring the monolithic section of cortical |
| 7163691 |
Bone graft |
January 16, 2007 |
| An improved demineralized bone matrix (DBM) or other matrix composition is provided that has been mixed with a stabilizing agent that acts as (1) a diffusion barrier, (2) a enzyme inhibitor, (3) a competitive substrate, or (4) a masking moiety. A diffusion barrier acts as a barrier so as |
| 6911045 |
Bio-implant insertion instrument |
June 28, 2005 |
| The present invention is directed to an impact-absorbing member for use with an implant insertion instrument and the placement of an implant in a recipient's body. Preferably, the implant is a spinal implant for insertion into the intervertebral space. The impact-absorbing member may |
| 6863694 |
Osteogenic implants derived from bone |
March 8, 2005 |
| An osteogenic osteoimplant in the form of a flexible sheet comprising a coherent mass of bone-derived particles, the osteoimplant having a void volume not greater than about 32% and a method of making an osteogenic osteoimplant having not greater than about 32% void volume, the method |
| 6855167 |
Spinal intervertebral implant, interconnections for such implant and processes for making |
February 15, 2005 |
| A cortical bone implant is formed of two or more planks of bone which are connected with one or more offset pins. The pins may be right circular cylinders inserted into a corresponding offset bore which offset bends the inserted pin. The bending creates compression and tensile loads in t |
| 6846853 |
Calcium phosphate bone graft material, process for making same and osteoimplant fabricated from |
January 25, 2005 |
| A calcium phosphate bone graft material comprising an amorphous calcium phosphate glassy phase of from about 30 to about 100 volume % is obtained by plasma spraying calcium phosphate-containing powder onto a target to produce a deposited layer and removing the deposited layer from the ta |
| 6843807 |
Osteoimplant |
January 18, 2005 |
| An osteoimplant comprises a solid aggregate of bone derived elements, adjacent bone-derived elements being bonded to each other through chemical linkages between their adjacent surface-exposed collagen. Various other components can be incorporated into the bone implant material such as |
| 6808585 |
Osteogenic implants derived from bone |
October 26, 2004 |
| An osteogenic osteoimplant in the form of a flexible sheet comprising a coherent mass of bone-derived particles, the osteoimplant having a void volume not greater than about 32% and a method of making an osteogenic osteoimplant having not greater than about 32% void volume, the method |
| 6752831 |
Biocompatible osteogenic band for repair of spinal disorders |
June 22, 2004 |
| Methods of repairing a joint formed by at least two bone sections are provided wherein a biocompatible osteogenic band fabricated from an osteogenic biological material such as bone, tendon, ligament and collagen is affixed to two or more bone sections. |
| 6746454 |
Implant insertion tool |
June 8, 2004 |
| A spinal implant tool comprises a steel shaft bifurcated into shaft portions at one end at which a pair of extensions extend from the bifurcated shaft portions. The extensions are flat members which extend from an implant impact element at the end of each of the shaft portions. A spi |
| 6733504 |
Cervical dowel and insertion tool |
May 11, 2004 |
| A dowel insertion tool includes a T-shaped handle and a hollow sleeve which extends distally from the T-shaped handle. A shaft extends from the handle through the hollow sleeve and includes a transverse extension. A rotatable knob having an annular channel positioned to receive the trans |
| 6706067 |
Spinal intervertebral implant and method of making |
March 16, 2004 |
| A C-shaped or ring shaped implant formed of cortical bone has its C-shaped or inner channel filled with a bone promoting material which is preferably demineralized bone fibers formed as a flexible wet sheet or may be cancellous bone, pressed bone fibers formed from demineralized cortical |
| 6696073 |
Shaped load-bearing osteoimplant and methods of making same |
February 24, 2004 |
| A load-bearing osteoimplant, methods of making the osteoimplant and method for repairing hard tissue such as bone and teeth employing the osteoimplant are provided. The osteoimplant comprises a shaped, coherent mass of bone particles which may exhibit osteogenic properties. In additi |
| 6666866 |
Spinal intervertebral implant insertion tool |
December 23, 2003 |
| An insertion tool for a C-shaped bone spinal wedge shaped intervertebral implant comprises an outer shank with a hollow core in which is placed a shaft with a threaded stud which passes through a bore in the shank at an implant insertion end of the shank. A flat extension member defines |
| 6638310 |
Intervertebral spacer and implant insertion instrumentation |
October 28, 2003 |
| An intervertebral spacer formed of dense cancellous human or animal bone is provided. In one preferred embodiment, the intervertebral spacer includes at least one bore which is dimensioned to receive a plug formed from cortical bone tissue. The cortical bone plug provides increased mecha |
| 6622864 |
Moisture resistant package for storing sterile items |
September 23, 2003 |
| A moisture resistant package for storing and transporting sterile items, such as specimens of human or animal tissue, comprises an inner tray that fits within a moisture resistant outer tray. The inner tray has a cavity for storing the specimen. The specimen is enclosed within the cavity |
| 6616698 |
Bone graft and guided bone regeneration method |
September 9, 2003 |
| An implantable, biocompatible, osteogenic bone graft comprises at least one zone of impermeability to soft tissue ingrowth which is integral with the bone graft. Application of the bone graft to a bone repair site leads to selective rapid new bone ingrowth and inhibits or prevents soft t |
| 6599520 |
Method of inducing new bone growth in porous bone sites |
July 29, 2003 |
| A method of treating a condition in a vertebrate animal characterized by bone having increased porosity and/or decreased bone mineral density. The porous bone is injected with an effective amount of a flowable bone composition. Also provided is a kit for the treatment of porous bone |
| 6569168 |
Intervertebral distractor and implant insertion instrument |
May 27, 2003 |
| A distractor/guide sleeve assembly is provided which includes a body having a cylindrical throughbore and a distractor assembly mounted thereon. The distractor assembly includes a rotatable dial, a pair of distractor rods, and two pairs of jaws. A plate is secured to the distal end of ea |
| 6547823 |
Intervertebral implant |
April 15, 2003 |
| An intervertebral implant having a composite wedge/dowel configuration is provided. The intervertebral implant includes a central body portion and a pair of radially extending wings. The radially extending wings can be tapered from a first end of the implant to the second end of the impl |
| 6530955 |
Ramp-shaped intervertebral implant |
March 11, 2003 |
| A ramp-shaped intervertebral implant is disclosed. The implant has a body having a first end, a second end, a top surface and a bottom surface. At least one of the top and bottom surfaces is tapered and converges towards the second end of the body. An opening extends through the body and |
| 6527773 |
Cervical dowel and insertion tool |
March 4, 2003 |
| A dowel insertion tool includes a T-shaped handle and a hollow sleeve which extends distally from the T-shaped handle. A shaft extends from the handle through the hollow sleeve and includes a transverse extension. A rotatable knob having an annular channel positioned to receive the trans |
| 6478825 |
Implant, method of making same and use of the implant for the treatment of bone defects |
November 12, 2002 |
| An implant is provided as a solid aggregate of bone-derived elements, e.g., particles, powders, granules, fibers, strips and/or large pieces of xenogenic, allogenic, transgenic, tissue engineered or autologous cortical and/or cancellous bone, employing as binding agent for the bone-deriv |
| 6458144 |
Methods for manufacturing skeletal implants |
October 1, 2002 |
| Instrumentation for manufacturing a bone dowel from human or animal cadaveric bone and instrumentation for evaluating the suitability of the bone and/or dowel for implant use after each step of the manufacturing process is provided. Such instrumentation for manufacturing a bone dowel |
| 6440444 |
Load bearing osteoimplant and method of repairing bone using the same |
August 27, 2002 |
| A load-bearing osteoimplant, method of making the osteoimplant and method for repairing bone using the osteoimplant are provided. The osteoimplant comprises a shaped, compressed composition of bone particles. The osteoimplant possesses a bulk density of greater than about 0.7 g/cm.sup.3 |
| 6436138 |
Process for producing flexible sheets from demineralized, elongate, bone particles |
August 20, 2002 |
| A process for fabricating shaped material from demineralized bone particles includes the steps of applying a liquid slurry of demineralized bone particles to a support, removing excess liquid form the demineralized bone particles to provide a cohering shaped mass of demineralized bone |
| 6413258 |
Rod-to-rod coupler |
July 2, 2002 |
| A rod-to-rod coupler includes a body having first and second coupler portions. Each coupler portion defines a concavity configured to receive a portion of an elongated spinal rod. A screw and nut assembly which includes a screw and a flanged nut is positioned adjacent each concavity. |
| 6383221 |
Method for forming an intervertebral implant |
May 7, 2002 |
| An intervertebral implant having a composite wedge/dowel configuration is provided. The intervertebral implant includes a central body portion and a pair of radially extending wings. The radially extending wings can be tapered from a first end of the implant to the second end of the impl |
| 6368322 |
Surgical bone screw |
April 9, 2002 |
| An interference screw suitable for surgical use is provided. The interference screw is constructed from bone and includes an elongated body having an outer threaded surface, a tapered insertion end and a central throughbore. Insertion tool engaging structure is formed along the walls |
| 6332779 |
Method of hard tissue repair |
December 25, 2001 |
| A method for promoting the growth of bone, periodontium, or ligament in a warm-blooded vertebrate, the method comprising: producing a surgical flap to expose the bone, periodontium or ligament; debriding the bone, periodontium or ligament to remove organic matter from the bone, perio |
| 6315795 |
Fusion implant device and method of use |
November 13, 2001 |
| An intervertebral prosthesis includes a bone graft implant member dimensioned for insertion within an intervertebral space defined between adjacent vertebrae and having at least first and second longitudinal sections with respective first and second cross-sectional dimensions. The fi |
| 6294187 |
Load-bearing osteoimplant, method for its manufacture and method of repairing bone using same |
September 25, 2001 |
| A load-bearing osteoimplant, method of making the osteoimplant and method for repairing bone using the osteoimplant are provided. The osteoimplant comprises a shaped, compressed composition of bone particles. The osteoimplant possesses a bulk density of greater than about 0.7 g/cm.sup.3 |
| 6294041 |
Method for an osteoimplant manufacture |
September 25, 2001 |
| The invention relates to an osteoimplant fabricated from a solid aggregate of bone derived elements possessing chemical linkages between their adjacent surface-exposed collagen. Also described are various other components which can be incorporated into the bone implant material such |
| 6277149 |
Ramp-shaped intervertebral implant |
August 21, 2001 |
| A ramp-shaped intervertebral implant is disclosed. The implant has a body having a first end, a second end, a top surface and a bottom surface. At least one of the top and bottom surfaces is tapered and converges towards the second end of the body. An opening extends through the body and |
| 6162258 |
Lyophilized monolithic bone implant and method for treating bone |
December 19, 2000 |
| Monolithic bone intended for implantation is treated in order to conserve its mechanical strength during lyophilization and subsequent packaging and to maintain the strength of the bone during the storage period preceding the rehydration and implantation of the bone. The method of treatm |
| 6123731 |
Osteoimplant and method for its manufacture |
September 26, 2000 |
| The invention relates to an osteoimplant fabricated from a solid aggregate of bone derived elements possessing chemical linkages between their adjacent surface-exposed collagen. Also described are various other components which can be incorporated into the bone implant material such |
| 6045580 |
Fusion implant device and method of use |
April 4, 2000 |
| An intervertebral prosthesis includes a bone graft implant member dimensioned for insertion within an intervertebral space defined between adjacent vertebrae and having at least first and second longitudinal sections with respective first and second cross-sectional dimensions. The fi |
| 5980948 |
Polyetherester copolymers as drug delivery matrices |
November 9, 1999 |
| A composition for delivering a biologically active agent to a host. The composition comprises a product including a biologically active agent encapsulated in a matrix comprising a polyetherester copolymer, such as a polyethylene glycol terephthalate/polybutylene terephthalate copolymer. |
| 5928238 |
Bone dowel cutter |
July 27, 1999 |
| A device is provided for cutting dowels from a bone mass which is easily disassembled for cleaning and sterilization. The dowel cutter includes an axial mounting member having a proximal end portion configured for engagement with a drill chuck and a distal end portion configured to r |
| 5899939 |
Bone-derived implant for load-supporting applications |
May 4, 1999 |
| A bone-derived implant is provided which is made up of one or more layers of fully mineralized or partially demineralized cortical bone and, optionally, one or more layers of some other material. The layers constituting the implant are assembled into a unitary structure to provide an |
| 5895426 |
Fusion implant device and method of use |
April 20, 1999 |
| An intervertebral prosthesis includes a bone graft implant member dimensioned for insertion within an intervertebral space defined between adjacent vertebrae and having at least first and second longitudinal sections with respective first and second cross-sectional dimensions. The fi |
| 5846484 |
Pressure flow system and method for treating a fluid permeable workpiece such as a bone |
December 8, 1998 |
| A pressure flow system and method for its use are provided for contacting the interior of a fluid permeable, e.g., porous, workpiece. The system includes a fluid pressure chamber having an inlet port and an opening formed in one of the chamber walls. An adjustable seal capable of pro |
