| Patent Number |
Title Of Patent |
Date Issued |
| 7553938 |
Method of providing a purified, virus safe antibody preparation |
June 30, 2009 |
| A method of preparing a purified, virus inactivated and virus safe antibody preparation from a starting solution comprising antibodies and contaminants, the method comprising the steps of: (a) adjusting the pH of the starting solution to about 4.6 to about 4.95 in particular to about |
| 7166709 |
Haemostatically active preparation containing vWF and method for the production thereof |
January 23, 2007 |
| A process for preparing a hemostatically active preparation containing von Willebrand factor (vWF) from a fraction of human plasma by chromatographic purification of a vWF-containing plasma fraction on an anion-exchange material which has the anion-exchanging groups on grafted polyme |
| 6893856 |
Process for preparing virus-inactivated factors 1X and X by membrane chromatography |
May 17, 2005 |
| Disclosed is a process for preparing agents containing virus-inactivated vitamin K-dependent plasma components as well as protein C, protein S, factors II, VII, IX and/or X as well as combinations thereof, such as, for example, PPSB preparations, wherein a source containing these compone |
| 6528246 |
Method for the inactivation of non-lipid-coated viruses |
March 4, 2003 |
| A method for the inactivation of viruses, in particular those having no lipid coats, in protein-containing compositions from blood, blood plasma or similar natural sources by treating said source, simultaneously or succesively, with an effective amount of dialkyl or trialkyl phosphates |
| 6518406 |
Method for purification of proteins |
February 11, 2003 |
| The present invention relates to methods for purification of antithrombin-III (AT-III) by precipitation of impurities. The said methods comprise (a) adding, to a solution comprising antithrombin-III, a saccharide and citrate, in an amount sufficient for impurities to precipitate whil |
| 6136865 |
Method for reduction of the infectiousness of potentially infectious material |
October 24, 2000 |
| A method for reduction of the viral infectiousness of potentially infectious material, such as human or animal body fluids or fractions derived therefrom from which biologically active substances can be isolated, wherein the infectiousness is due to non-lipid-coated viruses character |
| 6057164 |
Process for testing suitability of protein fractions containing factor VIII |
May 2, 2000 |
| The method for the aptitude testing of protein fractions containing factor VIII the further processing of which comprises a pasteurizing step is performed in such a way that the starting material is examined for fragments within a range of from 20 to 50 kD. Fragments of factor VIII w |
| 6007979 |
Method for reduction of the infectiousness of potentially infectious material |
December 28, 1999 |
| A method for reduction of the viral infectiousness of potentially infectious material, such as human or animal body fluids or fractions derived therefrom from which biologically active substances can be isolated, wherein the infectiousness is due to non-lipid-coated viruses character |
| 5919909 |
Process for the preparation of factor IX from biological sources |
July 6, 1999 |
| A process for the preparation of factor IX from a biological source by chromatography involves prior treatment with ammonium sulfate as a protein precipitant at a concentration of from 1.5-2.3 mol/l. |
| 5714590 |
Process for recovering a high-purity virus-inactivated factor VIII by anion exchanger chromatogr |
February 3, 1998 |
| Described is an economical process for the recovery of factor VIII from blood plasma or cryoprecipitate. In the process, anion exchanger chromatography is conducted using a separating material based on carriers containing hydroxyl groups, the surfaces of which carriers have been coat |
| 5648472 |
Process for preparing virus-inactivated immunoglobulin solutions |
July 15, 1997 |
| This invention describes a process for preparing virus-inactivated immunoglobulin solutions suitable for intra-venous application, characterized in that the immunoglobulin is treated with non-ionic surfactants which subsequently are removed by solid-phase extraction on hydrophobic ma |
| 5328694 |
Stable injectable solution of factor VIII |
July 12, 1994 |
| A stable, injectable solution containing factor VIII suitable for the treatment of humans, natural or synthetic disaccharides, preferably saccharose, in concentrations of from 0.1 to 0.65 mol/1, and one or more amino acids in concentrations of from 0.1 to 1.0 mol/1. A process for pre |