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Novo Nordisk A/S Patents
Assignee:
Novo Nordisk A/S
Address:
Bagsvaerd, DK
No. of patents:
1035
Patents:




Patent Number Title Of Patent Date Issued
RE39678 Meiosis regulating compounds June 5, 2007
Certain novel sterol derivatives can be used for regulating the meiosis in oocytes and in male germ cells.
RE37302 Peptide July 31, 2001
The invention employs GLP-1(7-37), GLP-1(7-36)amide, and certain related compounds in combination with an oral hypoglycaemic agent for treating diabetes mellitus.
RE36375 Treatment of Alzheimer's disease using azacyclic compounds November 2, 1999
The present invention relates to therapeutically active azacyclic compounds. The novel compounds are useful as stimulants of the cognitive function of the forebrain and hippocampus of mammals and especially in the treatment of Alzheimer's disease, severe painful conditions and glaucoma.
RE35822 Heterocyclic compounds June 9, 1998
The present invention relates to therapeutically active azacyclic compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful as stimulants of the cognitive function of the forebrain and hippocampus of mammals
D444226 Inhaler June 26, 2001
D353999 Dispenser January 3, 1995
D353711 Storage case for a blood coagulation meter December 27, 1994
D350195 Capillary tube holder for drawing blood August 30, 1994
D347894 Adaptor top for a pen syringe ampoule June 14, 1994
D336335 Lancet June 8, 1993
7615532 Insulin derivatives November 10, 2009
The present invention relates to insulin derivatives which are naturally occurring insulins or analogues thereof which have a side chain attached either to the .alpha.-amino group of the N-terminal amino acid residue of the B chain or to the .epsilon.-amino group of a Lys residue present
7614545 Electronic marking of a medication cartridge November 10, 2009
The invention relates to a marking of cartridges, carpules or any kind of package. The marking can be in an electronically readable form while being transparent. Hereby a marking with improved security for avoiding reading errors which ensures a mandatory visual inspection of content is
7598391 Heteroaryl-ureas and their use as glucokinase activators October 6, 2009
This invention relates to compounds of formula (I) ##STR00001## which are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
7597679 Safety system for an electrically driven medical delivery device and a computer-readable medium October 6, 2009
This invention relates to a safety system for an electrically driven medical delivery device for delivering a dose of medication, wherein the safety system is configured for preventing delivery of an erroneous dose of the medicament and comprising detector means for registering mecha
7595293 Stable pharmaceutical compositions September 29, 2009
Pharmaceutical composition for parenteral administration comprising a glucagon-like peptide and human serum albumin or a variant thereof.
7595172 Method for making acylated polypeptides September 29, 2009
The present invention related to a method of producing polypeptides in transformed host cells by expressing a precursor molecule of the desired polypeptide which are to be acylated in a subsequent in vitro step. The invention is also related to DNA-sequences, vectors and transformed host
7582769 Dicycloalkyl urea glucokinase activators September 1, 2009
Dicycloalkyl urea glucokinase activators compounds are glucokinase inhibitors useful for the treatment of diabetes. (I) ##STR00001##
7576062 Compounds with growth hormone releasing properties August 18, 2009
Disclosed are compounds of formula I ##STR00001## wherein R.sup.1, R.sup.2, R.sup.5, R.sup.6, R.sup.7, R.sup.8, G, J, L, M, a, b, c, d, e, and f are as defined in the specification, and compositions containing them. These compounds are useful for treating medical disorders resulting
7576059 Peptide derivatives August 18, 2009
A pharmacologically active peptide hormone derivative in which the parent peptide hormone has been modified by introducing either a lipophilic substituent, W, in the N-terminal amino acid or a lipophilic substituent, Z, in the C-terminal amino acid of the parent peptide hormone or an
7572884 Method for making acylated polypeptides August 11, 2009
The present invention related to a method of producing polypeptides in transformed host cells by expressing a precursor molecule of the desired polypeptide which are to be acylated in a subsequent in vitro step. The invention is also related to DNA-sequences, vectors and transformed host
7553293 Safety needle assembly June 30, 2009
The invention relates to a safety needle assembly for injecting a fluid into a human body comprising a cylindrical housing with a bottom surface supporting a needle cannula and a shield telescopically movable relative to the housing. A spring located within the housing urges the shield i
7544185 Needle device comprising a plurality of needles June 9, 2009
A needle device comprises a housing, a base portion having a mounting surface adapted for application to the skin of a patient, and a plurality of needles. Each needle comprises a distal pointed end adapted to penetrate the skin of the subject, and has a first position in which the d
7541430 Peptides for use in treating obesity June 2, 2009
Novel cyclic and linear peptides of the formula R.sup.1--X--X.sup.1--X.sup.2--X.sup.3--X.sup.4--X.sup.5--X.sup.6--X.sup.7- --X.sup.8--X.sup.9--X.sup.10--X.sup.11--R.sup.2 are useful in the treatment of obesity are provided.
7541373 Aryl carbonyl derivatives as therapeutic agents June 2, 2009
This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
7517854 Melanocortin receptor agonists April 14, 2009
Small cyclic peptides of the formula X1-X2-X3-X4-X5-X6-X7-R.sup.1 comprising 7-12 amino acid residues are provided. Said peptides are MC4 receptor agonists, and thus useful in the treatment of obesity and related diseases.
7500959 Medication delivery system with improved dose accuracy March 10, 2009
The invention relates to: A medication delivery device (1) for delivering a specific dose comprising a medication cartridge (11) having an outlet (111) and a piston (112), and means (12) for holding said cartridge, and a piston rod (13) being operable to engage and displace said piston,
7470250 Apparatus for automatic insertion of a solid medicine December 30, 2008
An apparatus for insertion of a medicine peg (3) into the skin (4) has a barrel (2) wherein the medicine peg (2) is stored and in which a plunger (8) behind said peg (2) can be moved to press the peg out through an end of the barrel (2) pressed against the skin (4) where it is intended t
7456276 Peptide purification by means of metal ion affinity chromatography November 25, 2008
A polymer substrate functionalized with a functionality comprising at least one cyclic, metal ion coordinating ligand group, the cyclic ligand group comprising at least 3 metal ion coordinating donor atoms independently selected from the group consisting of N, O and S.
7446091 Methods and preparations for curing clinically ill patients November 4, 2008
This invention relates to a life saving medicament for critically ill patients and a method of treatment. The composition is a pharmaceutically effective amount of a blood glucose regulator which is used to control the blood glucose level.
7419803 Nucleic acids encoding human coagulation Factor VII polypeptides September 2, 2008
The present invention relates to novel human coagulation Factor VIIa variants having coagulant activity as well as polynucleotide constructs encoding such variants, vectors and host cells comprising and expressing the polynucleotide, pharmaceutical compositions, uses and methods of t
7411039 GLP-2 compounds, formulations, and uses thereof August 12, 2008
The present invention relates to novel human glucagon-like peptide-2 (GLP-2) peptides and human glucagon-like peptide-2 derivatives which have a protracted profile of action as well as polynucleotide constructs encoding such peptides, vectors and host cells comprising and expressing
7407490 Delivery device and cartridge therefore August 5, 2008
The invention relates to a portable pump device and a cartridge therefore. The cartridge comprises a first reservoir for a flowable drug provided in combination with a second reservoir comprising a pump liquid, a pump chamber being associated with the first reservoir and adapted to recei
7402565 Processes for making acylated insulin July 22, 2008
A method is provided which allows high yields of acylated insulin. The method comprises expressing a singe-chain insulin precursor, preferably in yeast, cleaving the single-chain insulin precursor with a suitable protease which will open the peptide bond between the C-terminal amino
7397730 Device with time indicating means July 8, 2008
The invention relates to a timer device capable of performing one or more control actions in response to the time lapsed since a user initiated action took place. The timer device comprises contact means operatable between two conditions, timer means, and means for storing first and
7396903 Process for preparing insulin compounds July 8, 2008
A preferred way of converting insulin precursors into insulin compounds is to perform an enzymatic peptide cleavage in an aqueous medium and, thereafter, without removal of the intermediate product formed, to add an amino acid ester or a peptide ester and an organic solvent so that the
7387996 Formulations of insulin June 17, 2008
Stable insulin formulations can be prepared by mixing a monomeric insulin and a soluble acylated insulin analog.
7384967 Aryl carbonyl derivatives as therapeutic agents June 10, 2008
This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
7378390 Method for making insulin precursors and insulin precursor analogues having improved fermentatio May 27, 2008
Novel insulin precursors and insulin precursor analogs comprising a connecting peptide (mini C-peptide) of preferably up to 15 amino acid residues and comprising at least one Gly are provided. The precursors can be converted into human insulin or a human insulin analog. The precursors
7358238 Pharmaceutical use of fused 1,2,4-triazoles April 15, 2008
The use of fused 1,2,4-triazoles for modulating the activity of 11.beta.-hydroxysteroid dehydrogenase type 1 (11.beta.HSD1) and the use of these compounds as pharmaceutical compositions has been described. Also a novel class of fused 1,2,4-triazoles, their use in therapy, pharmaceuti
7344766 Injection-moulded stopper for medical containers March 18, 2008
The present invention relates to the field of pharmaceutical packaging. More specifically the present invention relates to a stopper made from a thermoplastic elastomer for the use in medical containers.
7332508 Substituted homopiperidine, piperidine or pyrrolidine derivatives February 19, 2008
A novel class of substituted homopiperidine, piperidine and pyrrolidine derivatives, methods for their preparation, pharmaceutical compositions comprising them and use thereof in the treatment of disorders related to the histamine H3 receptor. More particularly, the compounds possess
7317000 Glucose-dependent insulins January 8, 2008
The present invention relates to insulin derivatives having a built-in glucose sensor and a polyol moiety, capable to deliver insulin from an injected depot of an insulin derivative according to the invention as a function of the glucose concentration in the surrounding tissue.
7316999 Glucose dependent release of insulin from glucose sensing insulin derivatives January 8, 2008
Insulin derivatives having a built-in glucose sensor, capable of delivering insulin from a depot as a function of the glucose concentration in the surrounding medium (e.g. tissue), such that the rate of insulin release from the depot increases with an increased glucose concentration
7294626 Piperazines November 13, 2007
The present invention relates, inter alia, to novel piperazines of the following formula: ##STR00001## to the use of these compounds in the preparation of pharmaceutical compositions, to pharmaceutical compositions comprising the compounds, and to methods of treatment employing thes
7282029 Method and a system for assisting a user in a medical self treatment, said self treatment compri October 16, 2007
A method of self treating a disease, such as diabetes, includes collecting in one or more databases data representing values of parameters that related to the self treatment. The data is processed to provide a plurality of alternate choices between two or more actions that may be tak
7279470 Compounds and uses thereof for decreasing activity of hormone-sensitive lipase October 9, 2007
Use of compounds to inhibit hormone-sensitive lipase, pharmaceutical compositions comprising the compounds, methods of treatment employing these compounds and compositions, and novel compounds. The present compounds are inhibitors of hormone-sensitive lipase and may be useful in the
7278419 Method for treating diabetes mellitus in a patient October 9, 2007
The need for the delivery of insulin by injection can be reduced or eliminated by delivering aerosolized insulin. Repeatability of dosing is obtainable by using either regular insulin or monomeric insulin. When delivering insulin (not monomeric) by inhalation, the total inhaled volum
7276590 Ion exchange chromatography of proteins and peptides October 2, 2007
The present invention relates to an ion exchange chromatography process for purifying a peptide from a mixture containing the peptide and related impurities, and to an industrial method including such ion exchange chromatography process.
7273921 Method for producing acylated peptides September 25, 2007
The present invention provides a method for acylating one or more amino groups of a peptide where the acylation reaction is to be performed in an aqueous mixture containing less than 10% w/w aprotic polar solvent.
7241278 Injection device July 10, 2007
An injection device for injection of set doses of medicine from a cartridge, in which syringe a dose is set by screwing a nut up along a threaded piston rod, whereby a dose setting drum, which carries on its cylindrical surface along a helix a scale of which a number corresponding to

 
 
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