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Novo Nordisk A/S Patents
Assignee:
Novo Nordisk A/S
Address:
Bagsvaerd, DK
No. of patents:
1140
Patents:












Patent Number Title Of Patent Date Issued
RE41956 Dose setting limiter November 23, 2010
A limiting mechanism which prevents the setting of a dose, which exceeds the amount of liquid left in a cartridge of an injection device, is disclosed. The injection device is the type where a dose is set by rotating a dose setting member relative to a driver and away from a fixed st
RE39678 Meiosis regulating compounds June 5, 2007
Certain novel sterol derivatives can be used for regulating the meiosis in oocytes and in male germ cells.
RE37302 Peptide July 31, 2001
The invention employs GLP-1(7-37), GLP-1(7-36)amide, and certain related compounds in combination with an oral hypoglycaemic agent for treating diabetes mellitus.
RE36375 Treatment of Alzheimer's disease using azacyclic compounds November 2, 1999
The present invention relates to therapeutically active azacyclic compounds. The novel compounds are useful as stimulants of the cognitive function of the forebrain and hippocampus of mammals and especially in the treatment of Alzheimer's disease, severe painful conditions and glaucoma.
RE35822 Heterocyclic compounds June 9, 1998
The present invention relates to therapeutically active azacyclic compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful as stimulants of the cognitive function of the forebrain and hippocampus of mammals
D444226 Inhaler June 26, 2001
D353999 Dispenser January 3, 1995
D353711 Storage case for a blood coagulation meter December 27, 1994
D350195 Capillary tube holder for drawing blood August 30, 1994
D347894 Adaptor top for a pen syringe ampoule June 14, 1994
D336335 Lancet June 8, 1993
8586614 Urea glucokinase activators November 19, 2013
The invention provides a compound of general formula (I) ##STR00001## wherein the substituents are defined further in the application, as well as further embodiments hereof described in the attached embodiments. The present invention also provides use of the compounds of the invention f
8579869 Needle mounting system and a method for mounting a needle assembly November 12, 2013
A needle mounting system and methods for mounting a needle assembly on a needle mount are disclosed. The needle mounting system includes a needle hub having protrusions extending radially inward. A needle mount has a plurality of slots to receive the protrusions. The slots have a first
8579868 Medical delivery system with flexible blocking element November 12, 2013
A medical delivery system (200) having a container (202) and a dosing assembly (204), where the container is fastenable to the dosing assembly by a movement comprising a translatory movement followed by a rotational movement. One of the container and the dosing assembly comprises one or
8579861 Needle magazine November 12, 2013
A needle magazine for holding a plurality of injection needles (50) is described. The needle magazine comprises a first opening adapted to receive the device fluid access portion (120) of a medical delivery device. Each needle (50) is selectively moveable from a respective storage po
8575096 Rapid acting insulin analogues November 5, 2013
The invention is related to fast acting insulin analogues which can form soluble mix-tures (pre-mixed or self-mixed) with long acting insulin analogues. The fast action is achieved through monomerizing substitutions/deletions in the C-terminus of the B-chain of human insulin and the
8575091 Amylin analogues and pharmaceutical compositions thereof November 5, 2013
The invention relates to polypeptides comprising an amino acid sequence which is an analogue of human amylin, pharmaceutical compositions comprising these polypeptides, and these polypeptides for use as medicaments.
8575090 Amylin analogues and pharmaceutical compositions thereof November 5, 2013
The invention relates to polypeptides comprising an amino acid sequence which is an analogue of pramlintide, pharmaceutical compositions comprising these polypeptides, and these polypeptides for use as medicaments.
8574199 Coupling for injection devices November 5, 2013
The present invention concerns a prefilled injection device having a container and a dose setting mechanism encapsulated inside the housing. The housing is made from two parts which are locked together by a bayonet coupling: In addition to the bayonet coupling, the two parts are also
8298194 Injection device and a method of changing a cartridge in the device October 30, 2012
A refillable injection device (1) having a dose setting mechanism with a dose setting member (4) and a dose rod (11). The dose setting member and the dose rod engage during normal operation of the injection device, and they do not engage during change of cartridge. The dose setting membe
8298172 Medical skin mountable device and system October 30, 2012
A medical device is provided comprising a transcutaneous device unit and a process unit. The transcutaneous device unit may comprise a transcutaneous device for transporting a fluid through a skin portion of a subject, and a mounting surface adapted for application to the skin of the
8287861 Anti-human interleukin-20 antibodies October 16, 2012
Anti-human IL20 monoclonal antibodies that can reduce IL20 mediated activation of both IL20R1/IL20R2 and IL22R1/IL20R2 receptor complexes in one or more species, including humans, are described, as well as antigen-binding molecules such as, e.g., antigen-binding antibody fragments, a
8268967 Glycopegylated interferon .alpha. September 18, 2012
The present invention provides IFN-.alpha. conjugates including IFN-.alpha. peptides and modifying groups such as PEG moieties. The IFN-.alpha. peptide and modifying group are linked via an intact glycosyl linking group interposed between and covalently attached to the IFN-.alpha. pe
8267899 Injection device September 18, 2012
A medication dispensing device with a housing and a member wherein the member is moveable in a distal direction is useful in delivering medication to a patient. A fluid container can be used with the device and often has a moveable piston at one end and an outlet at the other. The me
8263634 Heteroaryl-ureas and their use as glucokinase activators September 11, 2012
This invention relates to compounds of formula (I) ##STR00001## which are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
8263551 Soluble, stable insulin-containing formulations with a protamine salt September 11, 2012
The present invention relates to pharmaceutical formulations comprising insulin, an insulin analog, an insulin derivative, or a combination of any of the foregoing, and a salt of protamine, to methods of preparing such formulations, and to uses of such formulations in the treatment of
8257318 Injection device having a rotatable scale drum September 4, 2012
The application disclosed concerns an injection device for apportioning set doses of a drug from a reservoir (40) to a subject. The injection device comprises a rotatable scale drum (50) which is screwed out from the proximal end of the injection device when a does is set. The rotata
8226618 Gearing mechanism for an injection device July 24, 2012
An injection device comprising: a base member (102); a plunger (104) for driving a piston in a distal direction; a driving member (106); and a gear mechanism (108) providing a gearing between the driving member (106) and the plunger (104) such that then the driving member (106) is moved
8222376 KIR-binding agents and methods of use thereof July 17, 2012
The present invention relates to agents and methods that are capable of augmenting NK-mediated killing of target cells by reducing inhibitory KIR signalling without reducing the binding of KIR to HLA-C. As described herein, transduction of negative signaling via KIR, 5 upon binding of KI
8221359 Injection device with cap July 17, 2012
A drug delivery device capable of working in at least two different modes which includes a dose injection mode and a set-up mode. The drug delivery device automatically changes from the dose injection mode to the set-up mode and vice versa in accordance with the detection of the cover by
8221356 Medication delivery system with a detector for providing a signal indicative of an amount of a s July 17, 2012
A medication delivery system, comprising: a movable part (230, 232) adapted to move relative to a stationary part; at least two conductors (234, 236) which are arranged such that an electrical characteristic is defined by the mutual position of the movable and the stationary part and
8221344 Apparatus for automatic insertion of a solid medicine July 17, 2012
An apparatus for insertion of a medicine peg (3) into the skin (4) has a barrel (2) wherein the medicine peg (2) is stored and in which a plunger (8) behind said peg (2) can be moved to press the peg out through an end of the barrel (2) pressed against the skin (4) where it is intended t
8211420 Interleukin-21 variants with altered binding to the IL-21 receptor July 3, 2012
The invention is concerned with IL-21 polypeptide variants having an altered binding to the common gamma chain (c) of the IL-21 receptor and the use thereof in therapy.
8206709 Anti-NKG2A antibodies and uses thereof June 26, 2012
Described herein are anti-NKG2A antibodies suitable for human therapy, including humanized versions of murine anti-NKG2A antibody Z270, as well as related methods and materials for producing and using such antibodies. Exemplary complementarity-determining regions (CDRs) sequences and sit
8206361 Injection device June 26, 2012
An injection device for injection of set doses of medicine from a cartridge, in which syringe a dose is set by screwing a nut up along a threaded piston rod, whereby a dose setting drum, which carries on its cylindrical surface along a helix a scale of which a number corresponding to
8202256 Injection device June 19, 2012
A medication dispensing device with a housing and a member wherein the member is moveable in a distal direction is useful in delivering medication to a patient. A fluid container can be used with the device and often has a moveable piston at one end and an outlet at the other. The me
8197450 Injection device June 12, 2012
An injection device for injection of set doses of medicine from a cartridge has a nut that is screwed up along a threaded piston rod during a dose setting operation. The nut is screwed along the piston rod by rotating a dose setting member. A rotational coupling mechanism includes an
8197449 Injection device comprising an optical sensor June 12, 2012
The present invention relates to an injection device comprising an optically-based sensor for determining the position or setting of a dose setting member arranged to set a dose to be injected from the injection device. In particular, the present invention relates to an injection dev
8177767 Cartridge and medical delivery system accommodating such cartridge May 15, 2012
A cartridge having a distal end provided with a mechanical coding. The coding has the form of a circular protrusion where the circular outer diameter is dedicated a specific concentration of insulin contained in the cartridge. The distal end of the cartridge is fitted in to a circular
8167841 Transcutaneous device assembly May 1, 2012
A medical device is provided comprising a cannula having a distal portion adapted to be arranged through the skin of the subject, and an outer needle arranged coaxially with and being axially moveable relative to the cannula, the needle comprising a pointed distal end, wherein the device
8158583 Soluble pharmaceutical compositions for parenteral administration comprising a GLP-1 peptide and April 17, 2012
Pharmaceutical composition for parenteral administration comprising a meal related insulin peptide and an insulinotropic peptide.
8153395 Method of making activated carboxypeptidases April 10, 2012
The invention is related to a method for making an activated carboxypeptidase in a fungi cell comprising introducing a DNA sequence encoding a proform of the carboxypeptidase wherein a Kex2 site has been introduced in the prosequence of the carboxypeptidase, culturing the fungi cell
8148412 Heteroaromatic glucokinase activators April 3, 2012
The present invention describes 2,3-di-substituted N-heteroaromatic propionamides, of Formula (I) wherein the substitution at the 3-position is an optionally substituted phenyl ring and the substitution at the 2-position is an alkyl or cycloalkyl group; pharmaceutical compositions co
8138185 Urea glucokinase activators March 20, 2012
This application relates to novel urea glucokinase activators and use of the compounds of the invention for preparation of a medicament for the treatment of various diseases, e.g. for the treatment of type 2 diabetes. Further encompassed is a pharmaceutical composition comprising a compo
8137325 Needle mounting system and a method for mounting a needle assembly March 20, 2012
A needle mounting system and methods for mounting a needle assembly on a needle mount are disclosed. The needle mounting system includes a needle hub having protrusions extending radially inward. A needle mount has a plurality of slots to receive the protrusions. The slots have a first
8129343 Acylated GLP-1 compounds March 6, 2012
Protracted GLP-1 compounds and therapeutic uses thereof.
8129146 Method for making insulin precursors and insulin precursor analogues having improved fermentatio March 6, 2012
Novel insulin precursors and insulin precursor analogs comprising a connecting peptide (mini C-peptide) of preferably up to 15 amino acid residues and comprising at least one Gly are provided. The precursors can be converted into human insulin or a human insulin analog. The precursors
8119775 Human anti-KIR antibodies February 21, 2012
Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies having antigen-binding
8118781 Fluid infusion system, a method of assembling such system and drug reservoir for use in the syst February 21, 2012
The present application relates to methods and devices for providing a reduced risk of free flow from medical devices such as an infusion pump. A medicament containing reservoir (100) is provided with a piston having a sealing portion (121) formed by a material of a first stiffness. The
8114959 Stabilized pharmaceutical peptide compositions February 14, 2012
Method for increasing the shelf-life of a pharmaceutical composition comprising a glucagon-like peptide which is prepared from a peptide product that has been dried at a pH above neutral pH.

 
 
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