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Novartis AG Patents
Assignee:
Novartis AG
Address:
Basel, CH
No. of patents:
924
Patents:


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Patent Number Title Of Patent Date Issued
RE40596 Rapamycin assay December 2, 2008
Monoclonal antibodies to rapamycin and to 40-O-alkylated derivatives of rapamycin are provided, together with novel haptens, immunogenic conjugates, and processes for making them and assay kits for using them.
PP11231 Verbena plant named `Morena` February 22, 2000
A new and distinct variety of Verbena plant, named Morena, characterized particularly as to novelty by large, early-appearing, vivid pink flowers, and a growth habit that is initially semi-erect but later spreading and hanging.
PP11197 Verbena plant named `Silvena` February 1, 2000
A new and distinct variety of Verbena plant, named Silvena, characterized particularly as to novelty by large, early-appearing purple flowers, and a growth habit that is initially semi-erect but later spreading and hanging.
PP11192 Verbena plant named `Mylena` January 25, 2000
A new and distinct variety of Verbena plant, named Mylena, characterized particularly as to novelty by large, early appearing, dark purple flowers, and a growth habit that is initially semi-erect but later spreading and hanging.
H1973 Human neutrophil collagenase splice variant July 3, 2001
The subject invention is related to human MMP-8alt genes and gene products and their differential expression when comparing a patient with a disease state to a control. A further aspect of the invention concerns compounds which antagonize the biological activity of MMP-8alt protein and m
D604502 Combined pill container and lid November 24, 2009
D591418 Nebulizer April 28, 2009
D579550 Inhaler October 28, 2008
D579549 Inhaler October 28, 2008
D579548 Inhaler October 28, 2008
D579547 Inhaler October 28, 2008
D579546 Inhaler October 28, 2008
D579545 Inhaler October 28, 2008
D579544 Inhaler October 28, 2008
D574230 Package for an ophthalmic product August 5, 2008
D573836 Spill resistant lid July 29, 2008
D553733 Tablet October 23, 2007
D548087 Bottle August 7, 2007
D538661 Bottle March 20, 2007
D530814 Combined capsule and tablets October 24, 2006
D529821 Food tray October 10, 2006
D529797 Food tray October 10, 2006
D527817 Inhaler September 5, 2006
D520635 Combine capsule and tablets May 9, 2006
D474841 Dosage device May 20, 2003
D420739 Injector February 15, 2000
D420736 Attachment for an inhaler February 15, 2000
D411801 Aerosol dispenser cap July 6, 1999
D410541 Inhaler June 1, 1999
7622484 Mixtures or organic compounds for the treatment of airway diseases November 24, 2009
A medicament comprising, separately or together, (A) a compound of formula (I) in free or pharmaceutically acceptable salt or solvate form and (B) a corticosteroid, for simultaneous, sequential or separate administration in the treatment of an inflammatory or obstructive airways disease,
7622483 .beta.2-adrenoceptor agonists November 24, 2009
Compounds of formula ##STR00001## in free or salt or solvate form, where Ar is a group of formula ##STR00002## Y is carbon or nitrogen and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, R.sup.10, X, n, p, q and r are as defined in the specification,
7615635 N-formyl hydroxylamines November 10, 2009
Novel N-formyl hydroxylamine compounds and their derivatives are disclosed. These N-formyl hydroxylamine compounds inhibit peptidyl deformylase (PDF), an enzyme present in prokaryotes. The compounds are useful as antimicrobials and antibiotics. The compounds of the invention display
7615609 Preparation of somatostatin peptides November 10, 2009
Provided is a process for preparing cyclic somatostatin analogues and the linear intermediates used in this process.
7615562 2-aminopyrimidine derivatives and their medical use November 10, 2009
A compound of formula I or a pharmaceutically acceptable salt, ester or prodrug thereof wherein the variables have the meanings as defined in the specification. Further disclosed are a method of inhibiting IKK activity using a compound of formula I, a method of inhibiting production of T
7615523 Lens care product containing dexpanthenol November 10, 2009
The present invention relates to contact lens care product comprising dexpanthenol. The invention similarly relates to the usage of a contact lens care compositions of this kind for cleaning and optionally disinfecting contact lenses.
7612238 Amino-propanol derivatives November 3, 2009
Compounds of formula I ##STR00001## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are as defined in the specification, processes for their production, their uses and pharmaceutical compositions containing them.
7612055 Macrocyclic lactams and pharmaceutical use thereof November 3, 2009
The present invention relates to novel macrocyclic compounds of the formula ##STR00001## wherein R.sub.1, R.sub.2, R.sub.3, U, V, W, X, Y, Z and n are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16 or 17, in free base form
7612054 Dibenzo[b,f]oxepine-10-carboxamides and pharmaceutical uses thereof November 3, 2009
The present invention pertains to novel dibenzo[b,f]oxepine-10-carboxamides compound to a process for the preparation of such compounds of formula I, their use as a pharmaceuticals, especially in the treatment of neurological and vascular disorders related to beta-amyloid generation
7612052 Combinations comprising epothilones and pharmaceutical uses thereof November 3, 2009
The invention relates to a combination which comprises (a) a bisphosphonate, a platinum compound or a vasculostatic compound and (b) an epothilone derivative of formula I ##STR00001## wherein A represents O or NR.sub.N, wherein R.sub.N is hydrogen or lower alkyl, R is hydrogen or lo
7605267 Process for the preparation of 5-(halocetyl)-8-(substituted oxy)-(1h)-quinolin-2-ones October 20, 2009
The invention relates to a process for preparing 5-(.alpha.-haloacetyl)-8-substituted oxy-(1H)-quinolin-2-ones. The process involves (i) reacting (a) 8-hydroxy-(1H)-quinolin-2-one with an acylating agent and a Lewis acid to form 5-acetyl-8-hydroxy-(1H)-quinolin-2-one; or (b) 8-hy
7595390 Industrially scalable nucleoside synthesis September 29, 2009
An industrially scalable two-step process for preparing a .beta.-L-2'-deoxy-nucleoside that results in a predominance of the .beta.- over the .alpha.-anomeric form of the compound is described. An optional third step may be used to prepare 3'-prodrugs of desirable .beta.-L-2'-deoxy-n
7592349 Diarylamine-containing compounds and compositions, and their use as modulators of c-kit receptor September 22, 2009
Described herein are compounds that include a diarylamine structural feature. Also described herein are methods for making such compounds, methods for using such compounds to modulate the activity of c-kit receptors, and pharmaceutical compositions and medicaments comprising such com
7589216 Process for preparing N-hydroxyformamido-propyl pyrrolidin compounds and intermediates September 15, 2009
The present invention is directed to a process for preparing intermediates that are useful to prepare certain antibacterial N-formyl hydroxylamine compounds which are peptide deformylase inhibitors. The process makes use .alpha. .beta.-lactarn intermediate. Certain optically pure interme
7589091 Hydroxamic acid derivatives September 15, 2009
Novel hydroxamic acid derivatives, e.g., of formula (I), wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as defined, are found to be useful as pharmaceuticals, e.g., for the suppression of TNF release and the treatment of autoimmune and inflammatory diseases, e.g., multiple scleros
7589079 Crystalline and amorphous forms of beta-L-2'-deoxythymidine September 15, 2009
Physical forms of beta-L-2'-deoxythymidine are disclosed that can be characterized by physical appearance, purity levels, Infra-Red and Raman spectroscopy, X-ray powder diffraction patterns, thermal properties, and methods of manufacture. These forms of beta-L-2'-deoxythymidine can be
7582782 Organic compounds September 1, 2009
Disclosed are .delta.-amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid amide compounds of formula (I) ##STR00001## and the salts thereof, having renin-inhibiting properties. Also disclosed are pharmaceutical compositions comprising these compounds and methods of administering them f
7582327 LbL-coated medical device and method for making the same September 1, 2009
The present invention provides a medical device, preferably an ophthalmic device, more preferably a contact lens, which comprises a core material and a biocompatible LbL coating non-covalently attached to said core material. The biocompatible LbL coating comprises at least one charge
7579467 N-phenyl-2-pyrimidine-amine derivatives August 25, 2009
The present invention relates to novel amides and a process for preparing these amides.
7579362 Aza-bicycloalkyl ethers and their use as alpha7-nAChR agonists August 25, 2009
The present invention relates to 1-aza-bicycloalkyl derivatives of formula I, ##STR00001## wherein X is CH.sub.2 or a single bond; Y is a group of formula ##STR00002## and wherein R has the meanings as defined in the specification, which compounds are alpha 7 nicotinic acetylcholine
7573974 Device and method for non-contact scanning of contact lens and contact lens mold geometry August 11, 2009
The invention relates to an apparatus and method for non-contact/non-destructive measurement of the geometry of molded ophthalmic lenses and the precision molds and tooling used in the manufacture of the ophthalmic lenses. In particular the present system uses micro computed tomograp
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