| Patent Number |
Title Of Patent |
Date Issued |
| 7554657 |
Accomodating device for specimen slides |
June 30, 2009 |
| A receiving device for object holders comprises a base part. A plurality of centering elements are connected with the base part. The centering elements are arranged such that a plurality of receiving areas for receiving one object holder each are configured. The centering elements fo |
| 7166423 |
Direct selection of cells by secretion product |
January 23, 2007 |
| Cells can be labeled with products which they secrete and release in an efficient manner by coupling the cells at their surface to a specific binding partner for the product and allowing the product to be captured by the specific binding partner as it is secreted and released. The pr |
| 7119248 |
Antibodies against epitopes with homology to self antigens, methods of preparation and applicati |
October 10, 2006 |
| This invention provides novel methods of obtaining autologous monoclonal antibodies (AMABs) to self-antigens or homologs thereof. The method involves obtaining a genetically engineered host animal that does not biosynthesize at least one epitope of the antigen and utilizes the lack o |
| 7030228 |
Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof |
April 18, 2006 |
| The invention provides antigen-binding fragments specific for dendritic cells and effective in treatment and/or diagnosing a variety of disorders. Methods of use are also provided as are methods for screening for additional such antigen-binding fragments and the products obtained the |
| 6900029 |
Method of selection of a population or subpopulation of a sample utilizing particles and gravity |
May 31, 2005 |
| A separation procedure for separating a selected desired or undesired population from a biological sample utilizing relatively heavy, dense particles and gravity sedimentation. The particles have one or more reactants bound thereto which are specific to and will bind with the selecte |
| 6730230 |
Use of high density microparticles for removal of pathogens |
May 4, 2004 |
| Methods of using high-density microparticles to bind and remove pathogens from biological fluids are disclosed. Pathogens include prions, viruses, bacteria and protozoa. |
| 6468432 |
Methods of modification of selected cells in a magnetic cell separation column |
October 22, 2002 |
| A method is provided for modifying cells retained in a high gradient magnetic cell separation column (HGMS). Selected cells within a heterogeneous mixture are labeled with a label comprising a magnetic particle and specific for the selected cells. The labeled, selected cells are appl |
| 6417011 |
Methods and materials for improved high gradient magnetic separation of biological materials |
July 9, 2002 |
| Improvements in the existing procedures and materials for conduct of high gradient magnetic separation (HGMS) are disclosed. The use of plastic coated matrices especially small spheres or balls which form superior magnetic gradient-intensifying supports are disclosed, along with improved |
| 6190870 |
Efficient enrichment and detection of disseminated tumor cells |
February 20, 2001 |
| Tumor cells, particularly carcinoma cells, are separated from peripheral blood by magnetic sorting. The tumor cells are magnetically labeled with antibodies directed to tissue specific antigens, preferably cytoplasmic proteins. Labeling for cytoplasmic antigens is accomplished first |
| 5916818 |
Isolation and characterization of allergen-binding cells for diagnosis of hypersensitivity |
June 29, 1999 |
| Methods and compositions are provided for the diagnosis of allergen hypersensitivity in a patient. Rare, allergen-specific cells are enriched from a complex cell population, e.g. a patient blood sample. The percentage of blood cells that bind to a particular allergen is less than 0.0 |
| 5786161 |
Isolation and characterization of allergen-binding cells for diagnosis of hypersensitivity |
July 28, 1998 |
| Methods and compositions are provided for the diagnosis of allergen hypersensitivity in a patient. Rare, allergen-specific cells are enriched from a complex cell population, e.g. a patient blood sample. The percentage of blood cells that bind to a particular allergen is less than 0.0 |
| 5779892 |
Magnetic separator with magnetic compensated release mechanism for separating biological materia |
July 14, 1998 |
| A magnetic separator device is provided for separating biological materials from carrier fluids using the technique of high gradient magnetic separation. A release compensator reduces the amount of force that an operator needs to apply in order to remove a separation column from the |
| 5711871 |
Magnetic separation apparatus |
January 27, 1998 |
| Improved magnetic separation devices for magnetic separation procedures are provided. The improved separation devices contain matrices which provide uniform pores or channels that reduce the entrapment of air or non-target substances, and decrease the loss of target substances due to mec |
