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Merck Patent GmbH Patents
Assignee:
Merck Patent GmbH
Address:
Darmstadt, DE
No. of patents:
864
Patents:


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Patent Number Title Of Patent Date Issued
RE41008 Method for producing 5-aryl nicotinaldehydes November 24, 2009
The invention relates to a process for the preparation of 5-arylnicotinaldehydes by reduction of the corresponding 5-arylnicotinic acids by catalytic hydrogenation in the presence of carboxylic anhydrides in which the catalyst used is a palladium/ligand complex, characterized in that
RE39605 Combination of optical elements May 1, 2007
The invention relates to a combination of optical elements comprising at least one optical retardation film and at least one broadband reflective polarizer, characterized in that the optical retardation film is comprising at least one layer of an anisotropic polymer material having a
RE36849 Anisotropic compounds and liquid crystal mixtures therewith September 5, 2000
Anisotropic compounds of the formula (1) specified in claim 1 are suitable, owing to their low .DELTA..epsilon./.epsilon..perp. values for liquid crystal displays which have high information densities of for examples up to 10.sup.6 image dots and accordingly need to be highly multiplexib
D493220 Inhaler July 20, 2004
8586684 Conjugated copolymer November 19, 2013
The invention relates to a conjugated copolymer comprising indenofluorene and triarylamine units and to its use in organic electronic devices.
8586659 Redispersible surfaced-modified particles November 19, 2013
The present invention relates to surface-modified particles which can be dispersed in organic solvents, and to the use thereof for incorporation into polymers, paints and coatings.
8586599 Polymorphic forms of 6-(1-methyl-1H-pyrazol-4-yl)-2-{3-[5-(2-morpholin-4-yl-ethoxy)-pyrimidin-- November 19, 2013
The present invention relates to 6-(1-methyl-1H-pyrazol-4-yl)-2-{3-[5-(2-morpholin-4-yl-ethoxy)-pyrimidin-- 2-yl]-benzyl}-2H-pyridazin-3-one dihydrogenphosphate, its solvates and crystalline modifications thereof. The present invention further relates to processes of manufacturing the
8586577 Diazepane acetamide derivatives as selective 11B-HSD1 inhibitors November 19, 2013
The present invention relates to diazepane-acetamide derivatives of formula I as selective inhibitors of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11.beta.-HSD-1) and the use of such compounds for the treatment and prevention of metabolic syndrome, diabetes, insulin res
8586545 Solid materials of {[(2S, 5R,8S,11S)-5-benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,6,9 November 19, 2013
The instant invention relates to novel solid materials of {[(2S,5R,8S,11S)-5-Benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,- 6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acetic acid}, methods for producing them, and the use of said solid materials in pharmaceuti
8585925 Liquid-crystalline medium and liquid-crystal display November 19, 2013
The present invention relates to dielectrically positive, preferably nematic, media comprising one or more polymerisable compounds, to polymer-stabilized media obtained therefrom, to the use thereof in liquid-crystal displays, and to these displays, in particular PSA-IPS, PSA-FFS and
8585922 Liquid-crystalline medium November 19, 2013
The invention relates to a liquid-crystalline medium comprising one or more compounds of the formula I ##STR00001## in which R.sup.0, ring A and L.sup.1-4 have the meanings indicated in Claim 1, and to the use thereof in electro-optical liquid-crystal displays.
8581262 Electronic devices comprising multi cyclic hydrocarbons November 12, 2013
The present invention relates to compositions comprising functionalized or un-functionalized multi cyclic hydrocarbons and functional organic compounds, which can be used in different electronic devices. The invention further relates to an electronic device comprising one or more org
8581096 Gel electrolytes for dye sensitized solar cells November 12, 2013
Replacing liquid electrolytes with solid or quasi-solid electrolytes facilitates the production of photovoltaic cells using continuous manufacturing processes, such as roll-to-roll or web processes, thus creating inexpensive, lightweight photovoltaic cells using flexible plastic subs
8580781 Pyridazinone derivatives November 12, 2013
Compounds of the formula (I), in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.4' have the meanings indicated in claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumors.
8575163 Pyrrolopyridinylpyrimidin-2-ylamine derivatives November 5, 2013
Pyrrolopyridinylpyrimidin-2-ylamine derivatives of the formula (I), in which R.sup.1-R.sup.6 and R.sup.1 have the meanings indicated in claim 1, are inhibitors of cell proliferation/cell vitality and can be employed for the treatment of tumours.
8575161 Benzofurane, benzothiophene, benzothiazol derivatives as FXR modulators November 5, 2013
The present invention relates to compounds of formula (I) wherein the substituents are as defined in the claims, including pharmaceutical compositions thereof and for their use in the treatment and/or prevention and/or amelioration of one or more symptoms of disease or disorders rela
8574456 Liquid-crystalline medium and liquid crystal display November 5, 2013
The invention relates to a liquid-crystalline medium comprising one or more compounds of the formula I ##STR00001## in which R.sup.0, X.sup.0 and L.sup.1-6 have the meanings indicated in Claim 1, and to the use thereof in electro-optical liquid-crystal displays.
8569295 Bicyclic urea compounds October 29, 2013
The invention provides novel substituted azaheterocyclic compounds according to Formula (I), their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.
8568526 Glass-ceramic discs for use in pigments October 29, 2013
The present invention relates to a glass composition comprising crystalline phases, and to glass flakes produced therefrom. These glass flakes can be used as base substrate for effect pigments. The glass flakes can furthermore be used in paints, coatings, printing inks, plastics and
8563729 Thienopyridone derivatives as AMP-activated protein kinase (AMPK) activators October 22, 2013
The present invention relates to compounds of formula (I) wherein R1, R2 and R3 are as defined in claim 1, including pharmaceutical compositions thereof and for their use in the treatment and/or prevention of diseases and disorders modulated by AMP agonists. The invention is also directe
8563678 Photovoltaic cell with thiazole-containing polymer October 22, 2013
Photovoltaic cells with thiazole-containing polymers, as well as related components, systems, and methods, are disclosed.
8563561 3-(3-pyrimidine-2-yl-benzyl)-[1,2,4] triazolo[4,3-b]pyrimidine derivatives October 22, 2013
The 3-(3-pyrimidin-2ylbenzyl)-1,2,4-triazolo[4,3-b]pyrimidine compounds of formula ##STR00001## in which R.sup.1, R.sup.2, R.sup.3, R.sup.3, R.sup.4 have the meanings indicated herein, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for
8562986 Engineered anti-alpha V-integrin hybrid antibodies October 22, 2013
The invention relates to engineered antibodies which specifically bind to integrin receptors, especially the alpha V integrin receptor subunit. The antibodies comprise the antigen binding sites (CDRs) of a known mouse anti-integrin antibody, as well as hybrid light chain variable sequenc
8562870 Polymer dopants October 22, 2013
A polymer dopant for electrially conducting, photoconducting and semiconducting components and devices and novel polymers comprising electron accepting groups that are suitable as polymer dopants.
8298315 Use of liquid-crystal displays, and processes for the recycling thereof October 30, 2012
The present invention relates to the use of liquid-crystal displays (LCDs), and to processes for the recycling thereof. The processes according to the invention are characterised in that the LCDs are employed at least partly as replacement for other raw materials. In general, the LCD
8293784 .alpha.-amino acid derivatives for improving solubility October 23, 2012
The invention relates to the use of .alpha.-amino acid derivatives for improving the solubility of sparingly soluble substances in water or aqueous solutions, and to mixtures and preferred compositions.
8289494 Birefringent polymer film with negative optical dispersion October 16, 2012
The invention relates to a polymer film having negative optical dispersion, novel polymerisable compounds and liquid crystal (LC) materials for its preparation, and the use of the polymer film and novel compounds and materials in optical, electrooptical, electronic, semiconducting or
8287875 Nucleic acids encoding a house dust mite allergen, Der p III, and uses therefor October 16, 2012
Isolated nucleic acids encoding an allergen of Dermatophagoides pteronyssinus, Der p III, are disclosed. A cDNA encoding a peptide having a Der p III activity and a predicted molecular weight of about 24,985 daltons is also described. The nucleic acids can be used as probes to detect
8282808 Use of phosphinic acids and/or phosphonic acids in redox processes October 9, 2012
The present invention relates to the use of phosphinic acids and/or phosphonic acids and salts thereof, preferably as surface-active compounds, in redox processes, in particular in electroplating technology, particularly preferably in electroplating baths, and to electroplating baths
8277907 Liquid-crystalline medium October 2, 2012
The present invention relates to a liquid-crystalline medium based on a mixture of polar compounds having negative dielectric anisotropy (.DELTA..di-elect cons.), which is distinguished by the fact that it has a value for the ratio .gamma..sub.1/.DELTA.n.sup.2 in the range 6-45 with
8268845 Tetrahydro- and dihydroquinazolinones September 18, 2012
The present invention relates to the use of tetrahydro- and dihydroquinazolinones of formula I as protein kinase activators or inhibitors, a method for their manufacture, their use for the preparation of a medicament for the treatment of diseases, their use for the manufacture of a p
8268293 UV protection September 18, 2012
The present invention relates to the use of compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, for the development of UV-A or UV-B protection during use, to corresponding novel compounds and compositi
8268191 Liquid-crystalline medium and liquid-crystal display September 18, 2012
The present invention relates to dielectrically positive liquid-crystalline media comprising one or more compounds of the formula I ##STR00001## in which the parameters have the meaning indicated in the specification, and optionally one or more compounds selected from the group of
8268069 Pearlescent pigments September 18, 2012
The present invention relates to pearlescent pigments based on glass flakes which are distinguished by the fact that they have the following layer structure: A) optionally a layer of SiO.sub.2, B) a high-refractive-index coating have a refractive-index n>1.8 which essentially cons
8263090 Variants of group 1 allergens from Poaceae having reduced allergenicity and maintained T-cell re September 11, 2012
The present invention relates to the preparation and use of variants of the group 1 allergens of the Poaceae (sweet grasses) which are characterised by reduced IgE reactivity compared with the known wild-type allergens and at the same time by substantially maintained reactivity with
8261964 Carton packaging with film internal container, prefabricated carton unit for the production ther September 11, 2012
In carton packaging having an outer folding carton and an inner folding carton which surrounds a film internal container, the inner folding carton is adhesively bonded by means of one of its carton body walls (14) to an adjacent carton body wall (6) of the outer folding carton. The o
8258151 3-aminoimidazo [1,2-A] pyridine derivatives as SGLT inhibitors September 4, 2012
Novel compounds of the formula I, in which X, Y, R, R', R.sup.1, R.sup.1', R.sup.1'', R.sup.2, R.sup.2', R.sup.2'', R.sup.3, R.sup.3', R.sup.4, R.sup.4' and n have the meanings indicated in Patent Claim 1, are suitable as antidiabetics ##STR00001##
8257617 Functional paste September 4, 2012
To provide functional paste with etching activity and good electrical properties. Functional paste comprising a metal powder, an etching agent, a binder and an organic solvent.
8247448 Butenoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions co August 21, 2012
The present invention relates to butenoic acid derivatives of the formula I: ##STR00001## in which R, R.sup.1, R.sup.2 and R.sup.3 are as defined in the description, and also to processes for the preparation thereof, to pharmaceutical compositions comprising them and to their use for t
8242128 1,3-benzoxazolyl derivatives as kinase inhibitors August 14, 2012
The invention relates to compounds of formula 1, the production and use thereof as a medicament for the treatment of diseases, particularly tumours and/or diseases caused, mediated or propagated by angiogenesis. The compounds of formula 1 are effective inhibitors of tyrosin kinases,
8236968 1,4-bis(2-thienylvinyl)benzol derivatives and their use August 7, 2012
The present invention relates to novel 1,4-bis(2-thienylvinyl)benzene derivatives, to conjugated polymers, dendrimers, blends, mixtures and formulations comprising same, and to the use thereof in electronic devices, in particular in polymeric organic light-emitting diodes.
8221652 Process of preparing regioregular polymers July 17, 2012
The invention relates to a process of preparing regioregular polymers, in particular head-to-tail (HT) poly-(3-substituted) thiophenes or selenophenes with high regioregularity and defined molecular weight, to novel polymers prepared by this process, to the use of the novel polymers
8211948 Lyophilized nanoemulsion July 3, 2012
The present invention relates to a lyophilized nanoemulsion comprising a lipophilic phase and one or more sucrose fatty acid esters, to the nanoemulsion which can be prepared from the lyophilized nanoemulsion by redispersion, and to a process for the preparation of the lyophilized na
8211277 Compounds containing organofluorochlorophosphate anions July 3, 2012
The present invention relates to compounds containing organofluorochlorophosphate anions, the preparation thereof and the use thereof, in particular as ionic liquids.
8207345 Tetrahydroquinolines for use as modulators of the mitotic motor protein Eg5 June 26, 2012
Compounds of the formula (I), in which W, R, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 have the meanings indicated in Claim 1, can be employed, inter alia, for the treatment of tumors. ##STR00001##
8207210 Aminoindazolylurea derivatives June 26, 2012
Novel aminoindazolylurea derivatives of the formula I (I), in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, X and Y have the meanings indicated in Claim 1, are SGK inhibitors and can be used for the treatment of SGK-induced diseases and complaints, such as diabetes, obesity, met
8206718 Expression and export of angiogenesis inhibitors as immunofusins June 26, 2012
A homodimeric protein of the invention has angiogenesis inhibiting activity. The homodimeric protein consists of two identical fusion proteins bound together as a homodimer. Each fusion protein comprises an immunoglobulin Fc region and a first target protein linked to the immunoglobu
8202584 Liquid-crystalline medium and liquid-crystal display June 19, 2012
Disclosed are a dielectrically negative, liquid-crystalline medium which contains a (first) dielectrically negative component (component A), which contains one or more dielectrically negative compounds of formula I ##STR00001## and a further (second) dielectrically negative component
8188248 Nucleic acids encoding interleukin-12P40 variants with improved stability May 29, 2012
Modified interleukin-12 (IL-12) p40 polypeptides are disclosed. The modified polypeptides have alterations in the IL-12p40 subunit to eliminate the protease site between positions Lys260 and Arg261. The modified IL-12p40 polypeptides according to the invention have improved stability
8188087 Crystalline (3-cyano-1H-indol-7-yl)-[4-(4-fluorophenethyl) piperazin-1-yl]methanone phosphate May 29, 2012
The present invention relates to novel crystalline forms of (3-cyano-1H-indol-7-yl)-[4-(4-fluorophenethyl)piperazin-1-yl]methanone phosphate and to pharmaceutical compositions containing said forms.
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