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McGill University Patents
Assignee:
McGill University
Address:
Quebec, CA
No. of patents:
192
Patents:


1 2 3 4


Patent Number Title Of Patent Date Issued
RE39299 INGAP protein involved in pancreatic islet neogenesis September 19, 2006
Cellophane wrapping (CW) of hamster pancreas induces proliferation of duct epithelial cells followed by endocrine cell differentiation and islet neogenesis. Using the mRNA differential display technique a cDNA clone expressed in cellophane wrapped but not in control pancreata was ide
PP8853 June-bearing strawberry named Chambly August 2, 1994
A Nordic-type strawberry variety named "Chambly" combines the characteristics of cold-hardiness, adaptability to various soil conditions, vigor and strength, absence of suckering and its high yield of firm, deep red fruit with raised neck, elevated calyx and uniform well-colored fles
7626005 Inhibitors of aminoglycoside 6'-N-acetyltransferases, compositions and uses thereof December 1, 2009
The present invention relates to novel inhibitors of aminoglycoside 6'-N-acetyltransferases, more specifically, AAC(6')-li and AAC(6')-ly, as well as compositions and uses thereof. Furthermore, the present invention relates to synthetic methodologies for preparing the inhibitors of a
7608839 Plasma source and applications thereof October 27, 2009
A low-power atmospheric pressure plasma source, comprising a plasma-forming region for injection of a plasma-forming gas; an excitation region for injection of a source of reactive species downstream of the plasma-forming region; and a narrow converging plasma exit for producing a na
7572798 Combi-molecules having signal transduction inhibitory properties and DNA damaging properties August 11, 2009
The present invention relates to a series of new chemical agents that demonstrate anti-tumor activity. More particularly, the present invention relates to molecules, referred to as "combi-molecules", that combine two major mechanisms of anti-tumor action. A combi-molecule is capable of
7553661 Stromal antigen-presenting cells and use thereof June 30, 2009
There is provided a stromal antigen-presenting cell capable of antigen presentation in the context of MHC II. When stimulated with IFN.gamma. the stromal cell expresses B7-H1 and/or CD80. These stromal cells can be used to generate an immune response in an animal.
7544816 (-)-Epigallocatechin gallate derivatives for inhibiting proteasome June 9, 2009
(-)-EGCG, the most abundant catechin, was found to be chemopreventive and anticancer agent. However, (-)-EGCG has at least one limitation: it gives poor bioavailability. This invention provides compounds of generally formula 10, wherein R.sub.1 is selected from the group of --H and C.sub
7501503 Compositions and methods for inhibiting RNase H activity of retroid reverse transcriptase March 10, 2009
The invention relates to oligonucleotide agents that inhibit RNase H activity of a retroid virus reverse transcriptase and are useful for inhibiting retroid virus proliferation and preventing or treating a retroid virus infection.
7474974 Embedded time domain analyzer for high speed circuits January 6, 2009
A method of providing an on-chip high-speed time domain digital analyzer for the characterization and analysis of signals within an integrated circuit is provided. The method involves processing the signal being characterized/analyzed in the digital domain irrespective of it's starti
7465714 Oligonucleotide inhibitors of MBD2/DNA demethylase and uses thereof December 16, 2008
Oligonucleotide inhibitors that inhibit expression of a mammalian MBD2/DNA demethylase (MBD2/dMTase) are provided. The oligonucleotide inhibitors can be used to inhibit the growth or proliferation of tumor cells in vitro and in vivo. The use of the oligonucleotide inhibitors in the t
7452540 Enhanced immunization and suppression of oral tolerance November 18, 2008
This invention provides for methods of immunizing mammals against tumors expressing a carcinoembryonic antigen using a carcinoembryonic immunogen modified to lack cellular immunosuppressive activity or CD1d binding. The invention further provides for use of a carcinoembryonic immunogen h
7447403 Integrated etched multilayer grating based wavelength demultiplexer November 4, 2008
An integrated etched multilayer grating-based wavelength multiplexer/demultiplexer is disclosed wherein an etched multilayer grating structure is monolithically integrated within the optical waveguide stack of the multiplexer/demultiplexer to reflectively diffract an input optical be
7440654 Wavelength multiplexer/demultiplexer comprising an optically dispersive stratified body October 21, 2008
The present invention provides a wavelength multiplexer/demultiplexer comprising a plurality of regions of optically permissive material. The plurality of regions are disposed adjacent one another in a side by side relationship in order to define a stratified body. The materials in a
7439035 Method of identifying or characterizing a compound that modulates ribonuclease H activity October 21, 2008
The invention relates to a substrate and method for the assay of ribonuclease H activity. The substrate comprises a DNA/RNA heteroduplex molecule having fluorophore and quencher molecules in close proximity, which emit a background level of fluorescence in the absence of ribonuclease
7427220 Amphibious robotic device September 23, 2008
A control system for a robotic device maneuverable in at least a liquid medium, the system having at least one visual sensor retrieving an image of the device's environment, an image analyzing module receiving the image, determining a presence of an object of a given type therein and
7423114 GD2 ligands September 9, 2008
The invention provides ligands of ganglioside GD2, including peptide ligands such as GGITNYNSALM; YCGGITNYNSACY; YCITNYNSCY; YCGGITNYNCY; YCTNYGVHCY; YCTNYGVCY; GGIANYNTS; YCGGIANYNCY; YCGGIANYNTSCY; and, YCIANYNTCY. GD2 ligands of the invention may for example be used to treat or di
7399746 Agents for wound healing July 15, 2008
The present invention relates to pharmaceutical compositions containing fragments of alpha-1 proteinase inhibitor (API) or chimeric proteins of API and insulin-like growth factor for use in stimulating wound healing.
7395200 Remote language interpretation system and method July 1, 2008
A method and system of providing language interpretation between a first person and a second person in visual contact with one another. The method comprises receiving from the remote language interpreter an audio signal emitted by the interpreter and video images of the interpreter;
7393837 Inhibition of PEX in the treatment of metabolic bone diseases July 1, 2008
The present invention relates to a method of treating metabolic bone diseases in a patient, which comprises the modulation of PEX activity to modulate the bone micro-environmental concentrations of critical bone anabolic agents, namely PTH and PTHrP. The present invention also provid
7364852 Short GCG expansions in the PAB II gene for oculopharyngeal muscular dystrophy and diagnostic th April 29, 2008
The present invention relates to a human PAB II gene containing transcribed polymorphic GCG repeat, which comprises a sequence as set forth in SEQ ID NO:3, which includes introns and flanking genomic sequence. The allelic variants of GCG repeat of the human PAB II gene are associated
7316731 Adsorption of contaminants from gaseous stream and in situ regeneration of sorbent January 8, 2008
Contaminant is removed from a gaseous stream, especially an air stream bearing the contaminant, by adsorption on a sorbent which is a resiliently compressible, electrically conductive, activated carbon cloth material, leaving a gaseous stream liberated of the contaminant; the carbon
7262151 Methods and compositions for production of lipo-chito oligosaccharides by rhizobacteria August 28, 2007
Lipo-chito oligosaccharides (LCOs) are produced by culturing rhizobacteria cells in or on a culture medium comprising at least one of: jasmonic acid or a derivative thereof; linoleic acid or a derivative thereof; or linolenic acid or a derivative thereof. Preferably, the rhizobacteria
7250068 Method of increasing photosynthesis in plants comprising an exposure thereof to lipochitooligosa July 31, 2007
The present invention relates to agriculture. More particularly, the invention relates to a method of increasing photosynthesis of a plant and more particularly of crop plants. In addition, the invention relates to a method of increasing photosynthesis and/or yield in crop plants, co
7186520 Substrate for assaying ribonuclease H activity March 6, 2007
The invention relates to a substrate and method for the assay of ribonuclease H activity. The substrate comprises a DNA/RNA heteroduplex molecule having fluorophore and quencher molecules in close proximity, which emit a background level of fluorescence in the absence of ribonuclease
7173002 150 KDA TGF-B1 accessory receptor acts a negative modulator of TGF-B signaling February 6, 2007
The present invention relates to a TGF-.beta.1 binding protein called r150. This protein has a GPI-anchor contained in r150 itself and not on a tightly associated protein and that it binds TGF-.beta.1 with an affinity comparable to those of the signaling receptors. Furthermore, the relea
7169411 Composition for delivery of biological agents and methods for the preparation thereof January 30, 2007
A composition for facilitating delivery of biological agents, comprising a therapeutic or diagnostic agent and a supramolecular complex, the latter comprising (i) a block copolymer, having at least one nonionic, water soluble segment and at least one polyionic segment, and (ii) at least
7138369 Compounds and methods for modulating apoptosis November 21, 2006
Cyclic peptides and compositions comprising such cyclic peptides are provided. The cyclic peptides comprise a classical cadherin cell adhesion recognition sequence HAV. Methods for using such peptides and compositions for inducing apoptosis in cadherin-expressing cells, such as cance
7132274 Method for identifying modulators of CLK-1 and UbiF activity November 7, 2006
The present invention provides methods for screening modulators of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone (DMQ) hydroxylation activity, inhibitors and activators of the activity, and methods of using such compounds. More particularly, this invention relates to modulators of
7129341 Identification of Candida albicans essential fungal specific genes and use thereof in antifungal October 31, 2006
The invention relates to the identification and disruption of essential fungal specific genes isolated in the yeast pathogen Candida albicans namely CaKRE5, CaALR1, and CaCDC24 and to the use thereof in antifungal diagnosis and as essential antifungal targets in a fungal species for
7127962 Four-degree-of-freedom parallel manipulator for producing Schonflies motions October 31, 2006
The present invention relates to a manipulating device (A) for producing Schonflies motions comprising a parallel array of at least two legs (B), each leg (B) including an actuator unit (C) having first and second ends and producing a pan-tilt motion, each leg (B) also including a passiv
7122155 Electron microscopy cell fraction sample preparation robot October 17, 2006
A parallel processing, fluid handling apparatus for concurrent temperature controlled preparation of a plurality of cell fraction samples adapted to be used for electron microscopic viewing. The apparatus comprises generally a sample receiving member, a fluid handling means, and a se
7115227 Heat pipe October 3, 2006
A heat pipe assembly (10/110), under vacuum and having a working substance charged therein, comprising generally an evaporator (12/112) adapted to evaporate the working fluid and a condenser (16/116). The heat exchanging condenser is in fluid flow communication with the evaporator. The
7098012 DNA demethylase, therapeutic and diagnostic uses thereof August 29, 2006
The present invention relates to a DNA demethylase enzyme having about 40 KDa, and wherein said DNA demethylase enzyme is overexpressed in cancer cells and not in normal cells. The present invention also relates to the therapeutic and diagnostic uses of the DNA demethylase.
7071375 Nuclear fertility restorer genes and methods of use in plants July 4, 2006
The present invention includes nuclear fertility restorer genes, proteins encoded by those genes and transgenic plants and plant cells containing those genes. More particularly, the nuclear fertility restorer genes can be used to restore fertility in cytoplasmic male-sterile plants such
7063944 Human methionine synthase reductase: cloning, and methods for evaluating risk of, preventing, or June 20, 2006
The invention features a novel gene encoding methionine synthase reductase. The invention also features a method for detecting an increased likelihood of hyperhomocysteinemia and, in turn, an increased or decreased likelihood of neural tube defects, cardiovascular disease, Down's Syn
7063842 Compounds and methods for inhibiting the interaction between .alpha.-catenin and .beta.-catenin June 20, 2006
Modulating agents for inhibiting an interaction between .alpha.-catenin and .beta.-catenin are provided. The modulating agents comprise one or more of: (a) a .beta.-catenin HAV motif; (b) a peptide analogue or mimetic of a .beta.-catenin HAV motif; or (c) an antibody or antigen-bindi
7045612 Human methionine synthase reductase: cloning, and methods for evaluating risk of neural tube def May 16, 2006
The invention features a novel gene encoding methionine synthase reductase. The invention also features a method for detecting an increased likelihood of hyperhomocysteinemia and, in turn, an increased or decreased likelihood of neural tube defects, cardiovascular disease, or cancer.
7035269 Method and apparatus for distributed synchronous clocking April 25, 2006
A method and an apparatus are provided for synchronizing clock signals in spatially distributed nodes in large, synchronous electronic, optical, optoelectronic or wireless systems, such as systems comprising arrays of microprocessors and memories, and telecommunication systems. The nodes
6979664 Composition for accelerating seed germination and plant growth December 27, 2005
Lipo Chitooligosaccharide (LCO) [NodBj-V(C18:1,Mefuc)] isolated from Bradyrhizobium japonicum strain 532C was able to stimulate seed germination/seedling emergence, or in the case of potato, sprouting, of a number of crop plants representing eight distantly related plant families (Po
6971276 Recovery of purified volatile metal such as lithium from mixed metal vapors December 6, 2005
The present invention is concerned with a method for extracting selectively a metal from a metal mixture in the gaseous phase. The method comprises heating the metal mixture to vaporize the metal; condensing the metal contaminants present in the vapor; reacting any contaminants remaining
6969608 Pharmaceuticals containing multipotential precursor cells from tissues containing sensory recept November 29, 2005
Current sources of neural stem and progenitor cells for neural transplantation are essentially inaccessible in living animals. This invention relates to neural precursor cells (stem cells, progenitor cells or a combination of both types of cells) isolated from the olfactory epitheliu
6967238 Compounds and methods for modulating cell adhesion November 22, 2005
Cyclic peptides comprising a cadherin cell adhesion recognition sequence HAV, and compositions comprising such cyclic peptides, are provided. Methods for using such peptides for modulating cadherin-mediated cell adhesion in a variety of contexts are also provided.
6951970 Method for enhancement of naturally occurring cytoplasmic male sterility and for restoration of October 4, 2005
The present invention relates to methods for enhancement of naturally occurring cytoplastic male sterility and for restoration of male fertility and uses thereof in hybrid crop production. There is also disclosed a method for restoration of male fertility to cytoplasmic male sterile
6949378 C. elegans gro-1 gene September 27, 2005
The invention relates to the identification of gro-1 gene and to demonstrate that the gro-1 gene is involved in the control of a central physiological clock. Also disclosed are four other genes located within the same operon as the gro-1 gene.
6931579 Integrated excitation/extraction system for test and measurement August 16, 2005
An integrated test core for mixed-signal circuits comprises a periodic waveform generator capable of generating arbitrary band-limited waveforms for excitation purposes and a waveform digitizer for extracting an arbitrary waveform from the test circuit's analog response signal. The d
6917320 Method and device for use in DC parametric tests July 12, 2005
A system and device suitable for use in performing a DC parametric test on an external load is provided. The device may be configured to apply a desired voltage or current to the external load. The circuit device receives a forcing parameter signal at an input and releases at an output
6914548 Programmable DC voltage generator July 5, 2005
An efficient technique for generating accurate on-chip DC reference voltages is based on filtering a digital pulse modulated sequence in order to extract its average value encoding a DC level, A passive on-chip filter is used for simplicity with an all-digital modulator implementation.
6914044 Compounds and methods for modulating cell adhesion July 5, 2005
Cyclic peptides and compositions comprising such cyclic peptides are provided. The cyclic peptides comprise a cadherin cell adhesion recognition sequence HAV. Methods for using such peptides and compositions for modulating cadherin-mediated cell adhesion in a variety of contexts are
6902926 Toxoplasma gondii apical membrane antigen-1 June 7, 2005
The invention provides polypeptide fragments derived from TgAMA-1, nucleic acids that encode the polypeptide fragments, and TgAMA-binding polypeptides such as antibodies. Methods for using the polypeptide and nucleic acid molecules to produce vaccines are also provided. In addition t
6861518 Preparation of phosphorothioate oligomers March 1, 2005
Methods and Intermediates for the Preparation of Oligomers Containing Diastereomerically Enriched Phosphorothioate Linkages are Disclosed.
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