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Leica Microsystems CMS GmbH Patents
Assignee:
Leica Microsystems CMS GmbH
Address:
Wetzlar, DE
No. of patents:
160
Patents:


1 2 3 4










Patent Number Title Of Patent Date Issued
D669511 Optical filter wheel for a microscope October 23, 2012
D660336 Detector for microscope May 22, 2012
D525636 Microscope July 25, 2006
8587865 Device for examining and manipulating microscopic objects with coupled illumination and manipula November 19, 2013
A device for examining and manipulating microscopic objects with a microscope having a light source that serves to illuminate the object, and which generates an illumination light beam that runs along and illumination beam path, that can be guided over or through the object by means
8293490 Method for high spatial resolution stochastic examination of a sample structure labeled with a s October 23, 2012
A method for high spatial resolution stochastic examination of a biological sample structure labeled with a labeling substance is described. The method comprises providing a biological sample structure; choosing such a labeling substance that has molecules present in a first state an
8263946 Method and apparatus for high-resolution optical scanning of a sample September 11, 2012
A method and an apparatus are suggested for high-resolution optical scanning, particularly in a laser scanning fluorescence microscope. A sample to be scanned comprises a first and a second substance that are switchable into a first and second energy state. In the scanning process, e
8259383 Beam combiner and a light source with such a beam combiner September 4, 2012
A beam combiner for combining at least two light beams (1, 2) into one combined light beam (3), in particular in the beam path of an optical arrangement, preferably of a microscope, is with respect to a flexible beam combination with structurally simple means characterized by an acou
8253937 Optical evaluation method by means of laser pulses and corresponding apparatus August 28, 2012
An optical evaluation method and an apparatus for performing said method are described. First laser pulses of a first type and second laser pulses of a second type that differs from the first type are sent onto a sample to be examined. The sample is hit with first incident light from the
8228600 Inverted microscope for high-contrast imaging July 24, 2012
An inverted microscope for the high-contrast imaging of objects includes multiple objectives configured to be disposable in an imaging beam path. Each objective has a respective objective pupil associated therewith. A lens system is also provided for generating respective intermediate
8199407 Immersion objective, apparatus for forming an immersion film and method June 12, 2012
An immersion objective for microscopic investigation of a specimen is provided wherein an outer lens is disposed in an objective body. A delivery device including a cap that is disposed over the objective body so as to form a space adapted to receive an immersion liquid is also provi
8164829 System for recording and representing images of preparations April 24, 2012
A system for acquiring and displaying images of preparations is provided. The system includes a first and second illumination device, each including an illumination source defining a respective illumination beam path amid configured to emit light to illuminate the preparation. A came
8102598 Microscope and pinching prevention apparatus for a microscope January 24, 2012
The present invention relates to a microscope (1). The microscope (1) comprises a microscope stand (3) and a component (8) arranged movably relative to the microscope stand (3). The microscope stand (3) and the movably arranged component (8) each comprise a surface (11, 10). A gap (9
8064121 Acousto-optical component November 22, 2011
An acousto-optical component is suggested, in particular for use in the beam path of an optical arrangement, preferably of a microscope, with a crystal for the passage of light. Sound waves are generated via an electrical transducer and passed through the crystal. The sound waves pas
8054561 Optical system for merging a first and a second partial image beam, each proceeding from a speci November 8, 2011
An optical system is described for merging a first and a second partial image beam emanating from a specimen into a resultant image beam allowing modification of the areal proportion of the respective first or second partial image beam in the resultant image beam. A stop arrangement
8014624 Method, arrangement, and software for optimizing the image quality of movable subjects imaged wi September 6, 2011
A method and an arrangement for optimizing the image quality of movable subjects imaged with a microscope system are proposed. The microscope system encompasses at least one objective that defines an image window. Motions of the subjects being observed are captured in the image frame. A
8009353 Comparison optical system August 30, 2011
A comparison optical system (1) comprising several image-acquiring optical subsystems is disclosed. A bridge (3) mechanically and optically connects the optical subsystems to one another. Each of the image-acquiring optical subsystems possesses an XYZ stage (8a, 8b), movable in motor
7999935 Laser microscope with a physically separating beam splitter August 16, 2011
The invention proposes a method for imaging at least one microscopic property of a sample and an apparatus with which the proposed method can be carried out. In the method, at least one coherent illumination light with at least one illumination wavelength is produced by means of at l
7986338 Microscope system and image production method July 26, 2011
A microscope system and an image production method utilizing a microscope having one or more setting elements for modifying at least one microscope setting, and a camera for acquiring a microscope image, which camera is operable in predeterminable image modes. At least one of the setting
7948629 Microscope and method for total internal reflection-microscopy May 24, 2011
A microscope for total internal reflection microscopy. The microscope includes at least one light source configured to provide an illumination light to an illumination beam path for an evanescent illumination of a specimen so as to reflect the illumination light at an interface to the
7903247 Method and microscope for high spatial resolution examination of samples March 8, 2011
A method and a microscope, in particular a laser scanning fluorescence microscope, for high spatial resolution examination of samples, the sample (1) to be examined comprising a substance that can be repeatedly converted from a first state (Z1, A) into a second state (Z2, B), the fir
7873241 Method for superimposing optical information in a scanning microscope January 18, 2011
A method for superimposing optical information in a scanning microscope includes determining a transformation matrix, and superimposing first optical information of a CCD image and second optical information of at least one piece of second image information using the transformation m
7835601 Device for generating a laser light beam November 16, 2010
A device for generating a laser light beam includes a module. The module includes at least one laser light source, and a mechanical, an electrical and/or an optical interface defined towards an outside of the module.
7830506 Method for high spatial resolution examination of samples November 9, 2010
A method for high spatial resolution examination of a sample, the sample to be examined including a substance that can be repeatedly converted from a first state into a second state, the first and the second states differing from one another in at least one optical property. The method
7817271 Confocal microscope and method for detecting by means of a confocal microscope October 19, 2010
The invention relates to a confocal microscope which illuminates a sample (15) by means of at least one light source. A detection light beam (17) is emitted from the sample (15). The detection light beam (17) is spectrally split up in a spatial manner by the dispersive element (20) a
7808699 Microscope lens for total internal reflection microscopy and microscope October 5, 2010
A microscope objective includes an optical fiber. The optical fiber can deliver light for total internal reflection microscopy. The optical fiber can couple illumination light directly into the microscope objective through the optical fiber.
7807108 Apparatus for receiving biological specimens October 5, 2010
An apparatus for receiving biological specimens, the apparatus being introducible into a laser microdissection device for laser microdissection of a biological specimen, includes a first element having a first opening extending from a first side to a second side of the first element.
7802027 Method for data processing in a scan microscope comprising a fast scanner and scan microscope co September 21, 2010
The process acquires data blocks in real-time with a fast scanner. The acquired data blocks are then transmitted to a computer system (23). The data blocks are then processed as a function of a frame burst ratio (N). The transmission of the acquired data blocks to the computer system is
7777942 Device for modifying the distance between a microscope objective and a microscope stage August 17, 2010
Disclosed is a device for modifying the distance between a microscope table and a microscope objective. The vertical adjusting mechanism of the microscope table encompasses a eccentric member which is rotatable about a shaft. At least one actuating button is mounted on the shaft. The
7764375 Imaging device for imaging microscopic or macroscopic objects July 27, 2010
The present invention relates to an imaging device (1) for imaging microscopic or macroscopic objects (5). The imaging device (1) comprises a light source (2), an illumination beam path (6), an imaging beam path (7) and an imaging optical means (4), in particular in the form of an ob
7760428 Specimen slide unit for holding a specimen that is to be examined under a microscope or analyzed July 20, 2010
A specimen slide unit for holding a specimen that is to be examined under a microscope or analyzed with a laboratory analysis system includes a specimen slide, a data carrier device and a signal element. The data carrier device has a radio frequency identification tag that can be read
7746552 Illumination module for evanescent illumination and microscope June 29, 2010
A microscope with a light source that produces an illumination light beam for evanescently illuminating a sample includes an adjustment mechanism with which the polarization of the illumination light beam may be changed.
7742226 Interference microscope, and method for operating an interference microscope June 22, 2010
The present invention concerns an interference microscope and a method for operating an interference microscope, in particular a 4.pi. microscope, standing wave field microscope, or I.sup.2M, I.sup.3M, or I.sup.5M microscope, at least one specimen support unit associated with the spe
7733483 Method for ascertaining the orientation of molecules in biological specimens June 8, 2010
A method of ascertaining the orientation of molecules in a biological specimen by total internal reflection includes focusing illuminating light through an objective in different positions in a plane of a pupil of the objective so as to generate a plurality of respective differently
7724363 Device for multifocal confocal microscopic determination of spatial distribution and for multifo May 25, 2010
Many points on a sample are tested simultaneously in parallel in an FCS method with multifocal illumination and/or detection.
7710641 Tube for a microscope May 4, 2010
A tube for a microscope includes an adaptation interface, a rotatable operator interface, a beam deflecting device, and a rotatable beam deflecting unit. The beam deflecting device includes a beam-splitting device. A rotation of the operator interface is constrainedly coupled to a ro
7679875 Protective circuitry for photomultiplier tubes March 16, 2010
An electronic circuit for protecting a photomultiplier against overloads is provided. The photomultiplier has a cathode, an anode, a plurality of dynodes and a voltage divider. The circuit includes a high-voltage source, which applies a high voltage to the photomultiplier. A protective
7679822 Broadband laser illumination device for a scanning microscope with output stabilization March 16, 2010
The arrangement for examining microscope preparations with a scanning microscope comprises a laser (1) and an optical means (12) which images the light generated by the laser (1) onto a specimen (13) that is to be examined. Provided between the laser (1) and the optical means (12) is an
7679741 Method and microscope for high spatial resolution examination of samples March 16, 2010
A method and a microscope, in particular a laser scanning fluorescence microscope, for high spatial resolution examination of samples, the sample (1) to be examined comprising a substance that can be repeatedly converted from a first state (Z1, A) into a second state (Z2, A), the fir
7676071 Method for illuminating a sample March 9, 2010
A method for illuminating a specimen or a region of the specimen (region of interest, ROI), the information indicating whether and in what manner a specific point on the specimen is to be illuminated, being stored in a data memory under a specific address. A change in the position, o
7675617 Optical array for the spectrally selective identification of light of a light beam March 9, 2010
Disclosed is an optical array (2) for the spectrally selective identification of light of a light beam, particularly for identifying light of a detecting light beam (3) in a preferably confocal scanning microscope (1). Said optical array comprises a means (18) for the spatial spectra
7675019 Method and device for adjusting at least one light beam in an optical system March 9, 2010
A device (70) is disclosed for adjusting a light beam (1) in an optical system (100), whereby the optical system (100) defines an optical axis (60). The device (70) for adjusting comprises means for coupling-in (3) of the light beam into a housing part (80) of the device (70). The means
7660035 Scanning microscope February 9, 2010
A scanning microscope includes at least one light source, an acousto-optical element, a beam deflection device and a beam guiding device. The at least one light source generates an illuminating light beam. The acousto-optical element spatially splits a sub-light beam from the illumin
7649682 Method for self-monitoring a microscope system, microscope system, and software for self-monitor January 19, 2010
This invention comprises a method, a software, and a microscope system for monitoring and controlling information loss. The observation of information that is not present and the comparison of ideal loss to actual loss generates an explanatory component by means of a rule set. The us
7646481 Method and microscope for high spatial resolution examination of samples January 12, 2010
A method and a microscope, in particular a laser scanning fluorescence microscope, for high spatial resolution examination of samples, the sample (1) to be examined comprising a substance that can be repeatedly converted from a first state (Z1, A) into a second state (Z2, B), the fir
7633622 Method for analyzing a sample and microscope for evanescently illuminating the sample December 15, 2009
A microscope with evanescent sample illumination and a method for testing samples are disclosed. A first evanescent field, which exhibits a first penetration depth in the sample, and a second evanescent field, which exhibits a second penetration depth in the sample that is greater than
7626706 Polarization interference microscope December 1, 2009
The present invention relates to a polarization interference microscope (1) for imaging objects (5). The polarization interference microscope (1) comprises a light source (2), an illumination beam path (6), an imaging beam path (7) and an objective (4). The illumination beam path (6)
7619732 Method and microscope for high spatial resolution examination of samples November 17, 2009
A method and a microscope, in particular a laser scanning fluorescence microscope, for high spatial resolution examination of samples, the sample (1) to be examined comprising a substance that can be repeatedly converted from a first state (Z1, A) into a second state (Z2, B), the fir
7602824 Device and method for supplying short-wavelength light October 13, 2009
The present invention broadly comprises a device for supplying light at an illumination wavelength shorter than 300 nm. The device includes a first subassembly, having a light source for delivering light at a wavelength that is at least twice as long as the illumination wavelength; a sec
7600926 Device for adjusting an optical fiber or an optical fiber bundle October 13, 2009
Disclosed is a device for adjusting an optical fiber (1) or an optical fiber bundle relative to a coupling point. Said device comprises a holding apparatus (2) for the fiber/s (1) and a mechanism (3) for positioning the fiber/s (1) in said holding apparatus (2). The positioning mecha
7599115 Raster microscope October 6, 2009
A scanning microscope includes an excitation light beam, a stimulation light beam, an objective, an optical component and an optical system, The excitation light beam optically excites a first area of a specimen. The stimulation light beam triggers a stimulated emission or an additional
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