| Patent Number |
Title Of Patent |
Date Issued |
| 7465713 |
Glucopyranosyloxypyrazole derivatives and use thereof in medicines |
December 16, 2008 |
| The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula: ##STR00001## wherein R represents a hydrogen atom, a lower alkyl group or a group forming a prodrug; one of Q and T represents a ##STR00002## group represented by the general fo |
| 7465712 |
Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and inte |
December 16, 2008 |
| The present invention relates to glucopyranosyloxybenzylbenzene derivatives represented by the general formula: ##STR00001## wherein R.sup.1 represents a hydrogen atom or a hydroxy(lower alkyl) group; and R.sup.2 represents a lower alkyl group, a lower alkoxy group, a lower alkylthi |
| 7446128 |
Agent for treating interstitial cystitis |
November 4, 2008 |
| A compound which can be used as an agent for treating interstitial cystitis. An agent for treating interstitial cystitis, which comprises a phenoxyacetic acid derivative represented by a general formula (I) ##STR00001## wherein R.sup.1 represents hydroxyl group or a lower alkoxy gro |
| 7429568 |
Glucopyranosyloxypyrazole derivatives and use thereof in medicines |
September 30, 2008 |
| The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula: ##STR00001## wherein R represents a hydrogen atom, a lower alkyl group or a group forming a prodrug; one of Q and T represents a group represented by the general formula: ##STR00002# |
| 7423185 |
Amino alcohol derivatives, pharmaceutical compositions containing the same, and use thereof |
September 9, 2008 |
| The present invention provides compounds represented by general formula (I): ##STR00001## or pharmaceutical acceptable salts thereof, wherein R.sup.1 and R.sup.2 are each hydrogen or lower alkyl; R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are each hydrogen, halogen, lower alkyl or lower |
| 7417169 |
Amino alcohol derivatives, medicinal composition containing the same, and use of these |
August 26, 2008 |
| The present invention provides compounds represented by general formula (I): ##STR00001## a prodrug thereof, or pharmaceutical acceptable salts thereof, wherein R.sup.1 is hydrogen or lower alkyl; each of R2 and R3 is independently hydrogen or lower alkyl; each of R.sup.4, R.sup.5 and |
| 7402692 |
Intermediates in producing phenoxyacetic acid derivatives and method of using the same |
July 22, 2008 |
| The present invention provides novel intermediates represented by general formula (I) etc. for preparing a phenoxyacetic acid derivative represented by general formula (X) or a pharmaceutically acceptable salt thereof, which has .beta.3-adrenoceptor stimulating activity and are usefu |
| 7396954 |
Intermediates in producing phenoxyacetic acid preventives and method of using the same |
July 8, 2008 |
| The present invention provides novel intermediates represented by general formula (I) etc. for preparing a phenoxyacetic acid derivative represented by general formula (X) or a pharmaceutically acceptable salt thereof, which has .beta.3-adrenoceptor stimulating activity and are usefu |
| 7393968 |
Intermediates in producing phenoxyacetic acid derivatives and method of using the same |
July 1, 2008 |
| The present invention provides novel intermediates represented by general formula (I) etc. for preparing a phenoxyacetic acid derivative represented by general formula (X) or a pharmaceutically acceptable salt thereof, which has .beta.3-adrenoceptor stimulating activity and are usefu |
| 7393838 |
Glucopyranosyloxypyrazole derivatives and use thereof in medicines |
July 1, 2008 |
| The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula: ##STR00001## wherein R represents a hydrogen atom, a lower alkyl group or a group forming a prodrug; one of Q and T represents a ##STR00002## group represented by the general fo |
| 7375113 |
Nitrogenous fused-ring derivatives, medicinal compositions containing the derivatives, and use t |
May 20, 2008 |
| The present invention provides nitrogen-containing fused-ring derivatives represented by the following general formula, or pharmaceutically acceptable salts thereof, or prodrugs thereof, which exhibit an excellent inhibitory activity in human SGLT and are useful as agents for the pre |
| 7375087 |
Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and inter |
May 20, 2008 |
| The present invention provides pyrazole derivatives represented by the general formula: ##STR00001## wherein R.sup.1 represents H, an optionally substituted C.sub.1-6 alkyl group etc.; one of Q and T represents a group represented by the general formula: ##STR00002## or a group rep |
| 7371730 |
Crystals of glucopyranosyloxybenzyl benzene derivative |
May 13, 2008 |
| The present invention provides crystals of 2-(4-methoxybenzyl)phenyl 6-O-ethoxycarbonyl-.beta.-D-glucopyranoside, pharmaceutical compositions containing the same and their uses, which exhibit excellent SGLT2 inhibitory activities, and are useful for treating or preventing diseases as |
| 7294618 |
Glucopyranosyloxypyrazole derivatives and medicinal use thereof |
November 13, 2007 |
| The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula: ##STR00001## wherein R.sup.1, R.sup.2 and R.sup.3 represent a hydrogen atom or a halogen atom; R.sup.4 represents a lower alkyl group or a halo(lower alkyl) group; and R.sup.5 re |
| 7271153 |
Nitrogenous heterocyclic derivatives, medicinal compositions containing the same, medicinal uses |
September 18, 2007 |
| The present invention provides nitrogen-containing heterocyclic derivatives represented by the general formula: ##STR00001## wherein X.sup.1 and X.sup.3 independently represent N or CH; X.sup.2 represents N or CR.sup.2; X.sup.4 represents N or CR.sup.3; and with the proviso that one |
| 7256215 |
Crystals of 5-hydroxycarbamimidoyl-2-hydroxybenzenesulfonamide derivative |
August 14, 2007 |
| The present invention provides a novel crystalline form of n-butyl[4-[2-[2-hydroxy-5-(N-hydroxycarbamimidoyl) benzenesulfonylamino]ethyl]-2'-methanesulfonyl-3-yloxy] acetate hydrochloride, pharmaceutical compositions containing the same and their uses, which exhibits excellent inhibi |
| 7230031 |
Thyroid hormone receptor ligand, medicinal compositions containing the same and use thereof |
June 12, 2007 |
| The present invention provides a compound represented by general formula (I): ##STR00001## or pharmaceutically acceptable salts thereof, wherein W is O, S(O).sub.m, CH.sub.2 and the like; R.sup.1 is halogen, lower alkyl, halo-lower alkyl, CN and the like; R.sup.3 is hydrogen and the |
| 7217832 |
5-amidino-2-hydroxybenzenesulfonamide derivatives, pharmaceutical compositions containing the sa |
May 15, 2007 |
| The present invention relates to a 5-amidino-2-hydroxybenzenesulfonamide derivative represented by the general formula: ##STR00001## wherein R.sup.1 is a hydrogen atom or an optionally substituted lower alkyl group; R.sup.2 is a di(lower alkyl)amino group, a lower alkyl group, a c |
| 7217697 |
Glucopyranosyloxypyrazole derivative medicinal composition containing the same medicinal use the |
May 15, 2007 |
| The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula: ##STR00001## wherein R.sup.1 is a hydrogen atom or a hydroxyalkyl group; one of Q and T is a group represented by the general formula; ##STR00002## the other is an optionally su |
| 7208524 |
5-amidino-2-hydroxybenzenesulfonamide derivatives, pharmaceutical compositions containing the sa |
April 24, 2007 |
| The present invention relates to a 5-amidino-2-hydroxybenzenesulfonamide derivative represented by the general formula: ##STR00001## wherein R.sup.1 is a hydrogen atom or an optionally substituted lower alkyl group; R.sup.2 is a di(lower alkyl)amino group, a lower alkyl group, a cyc |
| 7208520 |
Crystals of hydroxynorephedrine derivative |
April 24, 2007 |
| The present invention provides ethyl (-)-2-[4-[2-[[(1S,2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]amino]e- thyl]-2,5-dimethylphenoxy]acetate hydrochloride, crystalline forms thereof and pharmaceutical compositions containing them, which have excellent .beta..sub.3-adrenoceptor st |
| 7196203 |
Phenol derivatives and method of use thereof |
March 27, 2007 |
| The present invention provides novel phenol derivatives represented by the formula: ##STR00001## wherein the carbon atom marked with (S) represents a carbon atom in S configuration; Z represents the group represented by the formula: ##STR00002## or the formula: ##STR00003## wherein th |
| 7189702 |
Glucopyranosyloxypyrazole derivatives and medicinal use thereof |
March 13, 2007 |
| The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula: ##STR00001## wherein one of Q and T represents a group represented by the general formula: ##STR00002## while the other represents a lower alkyl group or a halo(lower alkyl) grou |
| 7166301 |
Immediate release medicinal compositions for oral use |
January 23, 2007 |
| The present invention relates to an immediate release oral pharmaceutical composition which comprises as an active ingredient calcium salt of a benzylsuccinic acid derivative represented by the formula: ##STR00001## or its hydrate, which is useful as an agent for the treatment of dia |
| 7160556 |
Immediate release medicinal compositions for oral use |
January 9, 2007 |
| The present invention relates to an immediate release oral pharmaceutical composition which comprises as an active ingredient calcium salt of a benzylsuccinic acid derivative represented by the formula: ##STR00001## or its hydrate, which is useful as an agent for the treatment of dia |
| 7160555 |
Immediate release medicinal compositions for oral use |
January 9, 2007 |
| The present invention relates to an immediate release oral pharmaceutical composition which comprises as an active ingredient calcium salt of a benzylsuccinic acid derivative represented by the formula: ##STR00001## or its hydrate, which is useful as an agent for the treatment of dia |
| 7129381 |
Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and inter |
October 31, 2006 |
| The present invention relates to glucopyranosyl-oxybenzylbenzene derivatives represented by the general formula: ##STR00001## wherein R.sup.1 represents a hydrogen atom, a hydroxy group, a substituted or unsubstituted amino group, a carbamoyl group, a substituted or unsubstituted(lo |
| 7115575 |
Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermedia |
October 3, 2006 |
| The present invention relates to glucopyranosyloxypyrazole derivatives represented by the general formula: ##STR00001## wherein R.sup.1 represents a hydrogen atom or a lower alkyl group; one of Q.sup.1 and T.sup.1 represents a group represented by the general formula: ##STR00002## |
| 7087579 |
Glucopyranosyloxypyrazole derivatives and medicinal use thereof |
August 8, 2006 |
| The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula: ##STR00001## wherein one of Q and T represents a group represented by the general formula: ##STR00002## while the other represents a lower alkyl group or a halo(lower alkyl) grou |
| 7084123 |
Glucopyranosyloxypyrazole derivatives and use thereof in medicines |
August 1, 2006 |
| The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula: ##STR00001## wherein R represents a hydrogen atom, a lower alkyl group or a group forming a prodrug: one of Q and T represents a group represented by the general formula: ##STR00002# |
| 7056892 |
Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermedia |
June 6, 2006 |
| The present invention relates to glucopyranosyloxypyrazole derivatives represented by the general formula: ##STR00001## wherein R.sup.1 represents a hydrogen atom or a lower alkyl group; one of Q.sup.1 and T.sup.1 represents a group represented by the general formula: ##STR00002## |
| 7053060 |
Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and inter |
May 30, 2006 |
| The present invention relates to glucopyranosyloxybenzylbenzene derivatives represented by the general formula: ##STR00001## wherein R.sup.1 represents a hydrogen atom, a hydroxy group, a substituted or unsubstituted amino group, a carbamoyl group, a substituted or unsubstituted (lo |
| 7045665 |
Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and inter |
May 16, 2006 |
| The present invention relates to benzylphenol derivatives represented by the general formula: ##STR00001## wherein R.sup.11 represents a hydrogen atom or a protected hydroxy(lower alkyl) group; and R.sup.12 represents a lower alkyl group, a lower alkoxy group, a lower alkylthio gr |
| 7022689 |
5-amidino-n-(2-aminophenethyl)-n-hydroxy-benzenesulffonamide derivative, medical composition con |
April 4, 2006 |
| The present invention relates to a 5-amidino-N-(2-aminophenethyl)-2-hydroxybenzenesulfonamide derivative represented by the general formula: ##STR00001## wherein R.sup.1 is a hydrogen atom or a lower alkyl group; R.sup.2 represents a hydrogen atom, an optionally substituted lower a |
| 6972283 |
Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermedia |
December 6, 2005 |
| The present invention relates to glucopyranosyloxypyrazole derivatives represented by the general formula: ##STR1##wherein R.sup.1 represents a hydrogen atom or a lower alkyl group; one of Q.sup.1 and T.sup.1 represents a group represented by the general formula: ##STR2##while the ot |
| 6872706 |
Glucopyranosyloxybenzylbenzene derivatives and medicinal compositions containing the same |
March 29, 2005 |
| The present invention relates to glucopyranosyloxybenzylbenzene derivatives represented by the general formula: ##STR1##wherein P represents a group forming a prodrug; and R represents a lower alkyl group, a lower alkoxy group, a lower alkylthio group, a lower alkoxy-substituted (low |
| 6849655 |
Aqueous liquid formulations |
February 1, 2005 |
| An aqueous liquid formulation which comprises a compound of formula I: ##STR1##wherein Y is a hydroxy group, a carboxyl group, an acyloxy group or an alkoxycarbonyl group; R is a lower alkyl group or a lower alkyl group with one or more halogen atoms; or a pharmaceutically acceptable sal |
| 6790865 |
2-methylpropionic acid derivatives and pharmaceutical compositions comprising the same |
September 14, 2004 |
| The present invention provides novel 2-methylpropionic acid derivatives represented by the general formula: ##STR1##(wherein R.sup.1 represents a hydrogen atom, a lower alkyl group or an aralkyl group; R.sup.2 represents a hydrogen atom, a lower alkyl group or a halogen atom; A repre |
| 6696489 |
2-Methylpropionic acid derivatives and medicinal compositions containing the same |
February 24, 2004 |
| The present invention provides novel 2-methylpropionic acid derivatives represented by the general formula: ##STR1##(wherein R.sup.1 represents a hydrogen atom, a lower alkyl group or an aralkyl group; R.sup.2 represents a hydrogen atom a lower alkyl group or a halogen atom; A repres |
| 6552083 |
Agents inhibiting chronic rejection reactions after organ transplantation |
April 22, 2003 |
| The present invention relates to an agent for inhibiting diseases associated with chronic rejection after organ transplantation, such as transplanted heart-accelerated coronary arteriosclerosis, containing as an active ingredient N-(3,4-dimethoxycinnamoyl)anthranilic acid represented |
| 6538152 |
Phenoxyacetic acid derivatives and medicinal compositions containing the same |
March 25, 2003 |
| The present invention provides novel phenoxyacetic acid derivatives represented by the general formula: ##STR1##wherein R.sup.1 represents a hydroxy group, a lower alkoxy group, an aralkoxy group, an amino group, or a mono or di(lower alkyl)amino group; one of R.sup.2 and R.sup.3 is |
| 6399660 |
Aminoethylphenoxyacetic acid derivatives and drugs for pain remission and calculi removal promot |
June 4, 2002 |
| Novel aminoethylphenoxyacetic acid derivatives represented by the general formula: ##STR1##(wherein R.sup.1 represents a hydrogen atom, a lower alkyl group or an aralkyl group; R.sup.2 represents a hydrogen atom or a halogen atom; the carbon atom marked with (R) represents a carbon a |
| 6376707 |
Crystal polymorphism of aminoethylphenoxyacetic acid derivative |
April 23, 2002 |
| The present invention relates to a crystalline polymorph of 2-[4-[2-[[(1S,2R)-2-hydroxy-2-(4-hydroxy-phenyl)-1-methylethyl]amino]ethyl ]phenoxy]acetic acid having strong diffraction peaks (diffraction angle: 2.theta..+-.0.1.degree.) at 10.8, 19.1, 19.3, 19.8, 20.6 and 27.0.degree. in |
| 6353025 |
Phenylaminoalkylcarboxylic acid derivatives and pharmaceutical compositions comprising the same |
March 5, 2002 |
| The present invention provides novel phenylaminoalkyl-carboxylic acid derivatives represented by the general formula: ##STR1##(wherein R.sup.1 represents a hydroxy group, a lower alkoxy group, an aralkoxy group, an amino group, an alicyclic amino group or a mono or di(lower alkyl)ami |
| 6310086 |
Indole derivatives and medicinal compositions containing the same |
October 30, 2001 |
| The present invention relates to indole derivatives represented by the general formula: ##STR1##(wherein R represents an ethyl group or a 2,2,2-trifluoroethyl group; Y represents a hydroxy group or a pivaloyloxy group; and the carbon atom marked with (R) represents a carbon atom in ( |
| 6303655 |
Preventives or remedies for diseases affecting excessive proliferation of retinal pigment epithe |
October 16, 2001 |
| The present invention relates to an agent for the prevention or treatment of diseases associated with excessive proliferation of retinal pigment epithelial cells such as proliferative vitreoretinopathy comprising as the active ingredient N-(3,4-dimethoxycinnamoyl)anthranilic acid represe |
| 6239177 |
Tranilast-containing preparation for external application and method of producing the same |
May 29, 2001 |
| An external preparation containing tranilast which is excellent in the release of the active ingredient contained therein, achieves a high percutaneous absorption, fully ensures the effective drug concentration in the skin tissue and little irritates the skin This preparation is composed |
| 6136852 |
3,4-disubstituted phenylethanolaminotetralincarboxylic acid derivatives |
October 24, 2000 |
| The present invention relates to 3,4-disubstituted phenylethanolaminotetralincarboxylic acid derivatives represented by the general formula: ##STR1## [wherein Q represents a vinylene group or a group represented by the general formula:(wherein A represents an oxygen atom or a met |
| 6133266 |
3,4-disubstituted phenylethanolaminotetralincarboxamide derivatives |
October 17, 2000 |
| The present invention relates to 3,4-disubstituted phenylethanolaminotetralincarboxamide derivatives represented by the general formula: ##STR1## (wherein A represents a lower alkylene group; B represents an amino group, a di(lower alkyl)amino group or a 3 to 7-membered alicyclic |
| 6046192 |
Phenylethanolaminotetralincarboxamide derivatives |
April 4, 2000 |
| The present invention relates to a phenylethanolaminotetralincarboxamide derivative represented by the general formula: ##STR1## (wherein A represents a lower alkylene group; B represents an amino group, a di(lower alkyl)amino group or a 3 to 7-membered alicyclic amino group whic |
