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Hoechst Aktiengesellschaft Patents
Assignee:
Hoechst Aktiengesellschaft
Address:
Frankfurt am Main, DE
No. of patents:
4942
Patents:












Patent Number Title Of Patent Date Issued
RE35754 Cephem derivatives March 24, 1998
Cephem derivatives of the general formula ##STR1## is which the R.sub.2 O group is in the syn-position, a process for their manufacture and pharmaceutical formulations which are active against bacterial infections and contain these compounds.
RE35389 Process for the preparation of N-phosphonomethylglycine December 3, 1996
A process for the preparation of N-phosphonomethylglycine by reaction of aminomethanephosphonic acid and glyoxylic acid in the molar ratio 1:2 in aqueous medium.
RE35292 Process for separating organometallic compounds and/or metal carbonyls from their solutions in o July 9, 1996
Organometallic compounds and/or metal carbonyls are separated from their solutions in organic media with the aid of semi-permeable membranes made of aromatic polyamides.
RE34901 Optical waveguide with polymer core and polymer cladding April 11, 1995
An optical waveguide having a core/sheath structure whose sheath comprises a terpolymer based on vinylidene fluoride, tetrafluoroethylene and hexafluorpropylene, is suitable for transmission paths of ca. 10 to 100 m an can also be used at a temperature of above 100.degree. C. without
RE34865 Cephalosporin derivatives February 21, 1995
Cephemcarboxylic acid esters of the general formula ##STR1## pharmaceutical preparations which are active against bacterial infections, which contain such cephem derivatives, a process for the preparation of the cephem derivatives and the pharmaceutical preparations, and also the
RE32015 Process for the manufacture of insulin, analogs and derivatives thereof October 29, 1985
A process for manufacture of insulin, analogs and derivatives thereof by treating an insulin compound wherein the A- and B-chains are linked by a bis-methionyl-carbonyl-bridge, with cyano bromide.
RE30783 Flame retarding linear polyesters and shaped articles thereof October 27, 1981
Flame-repellant linear polyesters are obtained by incorporating by condensation phosphorus-compounds having the formula ##STR1## wherein R and R.sub.1 are organic radicals which may also contain hereto atoms into the linear polyesters, preferably those from terephthalic acid and
RE30740 Insecticidal composition for ultra low volume application September 8, 1981
Ultra low volume formulations of endosulfan (6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzod ioxathiepine-3-oxide), comprising endosulfan, a mixture of a vegetable oil and aromatic hydrocarbons, and an epoxide stabilizer.
RE30700 Insecticidal compositions for ultra low volume application August 4, 1981
Ultra-low volume formulations of endosulfan (6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzod ioxathiepine-3-oxide), comprising endosulfan, a mixture of mono- or dicarboxylic acid (di)esters and aromatic hydrocarbons, and an epoxide stabilizer.
RE30650 Dispersing and stabilizing agents for dyestuffs June 16, 1981
Dispersions of pigments, disperse- or vat-dyestuffs, wherein the dispersing agent is formed either by cocondensation of a phenolic component, formaldehyde and an alkali metal sulfite or of a sulfonated phenolic component and formaldehyde. These dispersions are characterized in that t
6875589 Mini-proinsulin, its preparation and use April 5, 2005
A mini-proinsulin, in which the amino acid Arg bridges the A and the B chain instead of the C chain, shows insulin activity and is suitable for the preparation of pharmaceuticals for the treatment of diabetes mellitus. It can furthermore be converted into an insulin derivative simply usi
6867208 Vitronectin receptor antagonists, their preparation and their use March 15, 2005
The present invention relates to compounds of the formula Iin which A, B, D, E, F and G have the meanings given in the patent claims, to their preparation and to their use as medicaments. The compounds of the invention are used as vitronectin receptor antagonists and as inhibitors of bon
6723727 Substituted purine derivatives, processes for their preparation, their use, and compositions com April 20, 2004
The present invention relates to compounds of the formulae I and Ia ##STR1##in which X, Y, W, W.sup.a, G and G.sup.a have the meanings given in the patent claims, and their physiologically tolerable salts and their prodrugs, their preparation, their use, in particular as pharmaceutical
6632840 Monoacyl-substituted guanidines, a process for their preparation, their use as a medicament or d October 14, 2003
Monoacyl-substituted guanidines of formula III, or a salt or acid thereof, and their use as medicine or diagnostic aid: ##STR1##in which X(2) is ##STR2##
6620820 Inhibitors of bone reabsorption and antagonists of vitronectin receptors September 16, 2003
The present invention relates to 5-membered ring heterocycles of the formula I, ##STR1##in which E, F, G, W, Y and Z have the meaning given in the patent claims, to their preparation and to their use as medicaments.The novel compounds are used as vitronectin receptor antagonists and as
6596727 Substituted pyrimidines, processes for their preparation, and their use as pesticides and fungic July 22, 2003
Substituted 4-amino- and 4-alkoxy-cycloalkylpyrimidines, processes for their preparation, and their use as pesticides and fungicidesThe invention relates to compounds of the formula ##STR1##in which R.sup.1, R.sup.2, R.sup.3 and Q are as defined in the description, X is NH or oxygen and
6573362 Cythohesin-PH peptides that affect the ability of integrins to adhere June 3, 2003
Isolated cytohesin-PH peptides that can inhibit the beta-2 integrins from adhering, wherein the cytohesin-PH peptide has an amino acid sequence that comprises about a 140 amino acid domain from cytohesin-2. Assay kits comprising the peptides also are provided.
6555714 Inhibitors of hydroxyphenylpyruvate dioxygenase and an assay for identification of inhibitors April 29, 2003
Disclosed and claimed is an assay for identifying potential inhibitors of p-hydrophenylpyruvate dioxygenases (HPPD) from plants, in which an enriched HPPD from plants is incubated with a test substrate to be examined and the enzymatic activity of the enzyme is determined in compariso
6514952 Hydantoin derivatives as inhibitors of leucocyte adhesion and as VLA-4 antagonists February 4, 2003
Compounds of the formula I ##STR1##in which B, D, E, R, W, Y, Z, b, c, d, e, f, g and have the meanings indicated in the claims, are inhibitors of the adhesion and migration of leucocytes and/or antagonists of the adhesion receptor VLA-4 which belongs to the group of integrins. The i
6504057 Fluorophenyl-substituted alkenylcarboxylic acid guanidides, process for their preparation, their January 7, 2003
This invention relates to fluorophenyl-substituted alkenylcarboxylic acid guanidides, process for their preparation, their use as a medicament or diagnostic, and medicament containing them. An embodiment of the invention embraces compounds of the formula I: ##STR1##and the pharmaceut
6504042 Use of spiro compounds as materials in non-linear optics January 7, 2003
Spiro compounds of the formula I ##STR1##in which .psi. is C, Si, Ge or Sn and K.sup.1 and K.sup.2 independently of one another are conjugated systems, are suitable as materials in nonlinear optics.
6486189 Five-membered heterocycles having biphenylsulfonyl substitution, process for their preparation, November 26, 2002
Five-membered heterocycles having biphenylsulfonyl substitution, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them. Compounds of the formula I ##STR1##in which the symbols have the meanings indicated in the claims, have outstanding
6482947 Substituted (hetero) aryl compounds, process for their preparation, agents containing them and t November 19, 2002
Compounds of the formula I and their salts, as defined in claim 1, are suitable as safeners for protecting crop plants against the phytotoxic side-effects of herbicides.
6458909 Aryl-substituted poly (p-arylene-vinylenes), process for their preparation and their use in elec October 1, 2002
Poly(p-arylene-vinylenes) comprising repeating units of the formula (I), ##STR1##where the symbols and indices have the following meanings: Y.sup.1, Y.sup.2, Y.sup.3 : identical or different, CH, N; Aryl: an aryl group having from 4 to 14 carbon atoms; R', R": identical or different, ea
6436999 Diacyl-substituted guanidines, a process for their preparation, their use as medicine or diagnos August 20, 2002
Diacyl-substituted guanidines of the formula I ##STR1## are described where X(1) and X(2) are ##STR2## as defined herein. The compounds are suitable for use as antiarrhythmic pharmaceuticals possessing a cardioprotective component for the prophylaxis and treatment of infarction
6399653 Ring fused dihydropyrans, process for preparation and use thereof June 4, 2002
The invention relates to compounds of the formula I ##STR1##in which the radicals R.sup.1, R.sup.2, R.sup.3 and A have the meaning mentioned in the description. The invention further relates to a process for the preparation of the compounds of the formula I by means of solid-phase sy
6387895 Vitronectin receptor antagonists, their preparation and their use May 14, 2002
The present invention relates to compounds of the formula Iin which A, B, D, E, F and G have the meanings given in the patent claims, to their preparation and to their use as medicaments. The compounds of the invention are used as vitronectin receptor antagonists and as inhibitors of bon
6384202 Cell-specific active compounds regulated by the cell cycle May 7, 2002
A DNA sequence is described for the gene therapy of diseases associated with the immune system. In its essential elements, the DNA sequence is composed of an activator sequence, a promoter module and a gene for the active substance. The activator sequence is activated in a cell-specific
6365638 Process for preparation of hydrophilic or partially hydrophilic inorganic aerogels April 2, 2002
Process for preparation of hydrophilic or partially hydrophilic inorganic aerogels. The invention relates to a process for the preparation of hydrophilic or partially hydrophilic inorganic aerogels, which comprises pyrolyzing a hydrophobic inorganic aerogel in the presence of oxygen at
6361917 Process for patterning poly(arylenevinylene) polymer films by irradiation with light March 26, 2002
A process for forming a pattern which comprises irradiating with light a film of a poly(arylenevinylene) polymer represented by the following formula (I)wherein Ar is a substituted or unsubstituted divalent aromatic hydrocarbon group or a substituted or unsubstituted divalent heterocycli
6337325 Combined preparation for the therapy of immune diseases January 8, 2002
A combination preparation comprising a compound which has a phosphodiesterase-inhibiting action, and a compound which reduces the biologically effective intracellular Ca.sup.2+ content, is suitable for the treatment of immunological diseases.
6335451 Five-membered heterocycles having biphenylsulfonyl substitution, with sulfonylcyanamide side cha January 1, 2002
Five-membered heterocycles having biphenylsulfonyl substitution, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them. Compounds of the formula I ##STR1##in which the symbols have the meanings indicated in the claims, have outstanding
6335186 Process for the preparation of L-phosphinothricin by a coupled enzymatic reaction January 1, 2002
A coupled enzyme reaction of a transaminase with GOT activity and of a transaminase with L-phosphinothricin transaminase activity produces phosphinothricin in virtually quantitative yield and virtually without any contamination whatever by a natural amino acid when the amino donor gl
6329082 Hetero-spiro compounds and their use as electroluminescence materials December 11, 2001
Hetero-spiro compounds of the formula (I), ##STR1##where.PSI. is an element of the 4th main group of the Periodic Table with the exception of carbon, preferably Sn, Ge or Si, particularly preferably Ge or Si, andK.sup.1 and K.sup.2 are, independently of one another, conjugated systems,
6294562 Salts of ethyl 3-(2-(4-(4-amino-imino-methyl)phenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl )ac September 25, 2001
The present invention relates to ethyl 3-(2-(4-(4-(amino-imino-methyl)-phenyl)-4-methyl-2,5-dioxoimidazolidin-1-y l)acetylamino)-3-phenylpropionate salts of the formula I, ##STR1##in which HM is maleic acid, and to their physiologically tolerated salts, thereof, to processes for their
6280744 Use of inorganic aerogels in pharmacy August 28, 2001
The invention relates to the use of inorganic aerogels as an auxiliary and/or excipient for pharmaceutical active compounds and/or preparations.
6251449 Cellulose-hydrate-based food casings impregnated with liquid smoke and process for producing June 26, 2001
A cellulose-hydrate-based food casing impregnated on its inside with liquid smoke which has a pH of about 2 to less than 4 and additionally contains a viscosity-increasing compound, an emulsifier and a triglyceride or lecithin.
6241888 Method of controlling the phosphorus concentration in biological wastewater purification plants June 5, 2001
The invention relates to a method of controlling a biological wastewater purification plant, in which the wastewater is aerated in an activation tank in the presence of an activated sludge and, to influence the properties of the activated sludge, phosphorus is added under controlled
6218415 Inhibitors or bone reabsorption and antagonists of vitronectin receptors April 17, 2001
Novel inhibitors of bone reabsorption and antagonists of vitronectin receptorsThe present invention relates to 5-membered ring heterocycles of the formula I, ##STR1##in which E, F, G, W, Y and Z have the meaning given in the patent claims, to their preparation and to their use as med
6218387 Vitronectin receptor anatagonists, their preparation and their use April 17, 2001
The present invention relates to compounds of the formula I,in which A, B, D, E, F and G have the meanings given in the patent claims, to their preparation and to their use as medicaments. The compounds of the invention are used as vitronectin receptor antagonists and as inhibitors of bo
6218140 Enhancer for eukaryotic expression systems April 17, 2001
An enhancer has been located in the upstream region of the major immediate early gene of human cytomegalovirus and has been isolated, which enhancer is more active than that from SV40 and has a wide host cell spectrum. Hence, it is suitable for eukaryotic expression systems wherein it ca
6214992 Use of theophylline derivatives for the treatment and prophylaxis of states of shock, novel xant April 10, 2001
Theophylline derivatives having at least one ether function in the structurally modified methyl radical in the 1-position that are useful in the treatment and prophylaxis of states of shock, new xanthine compounds having this substitution pattern, and processes for their preparation.
6214951 Cycloolefin copolymers having high tear strength and low optical attenuation April 10, 2001
Thermoplastic cycloolefin copolymers (COCs) having high tear strength and low optical attenuation, a process for their preparation, and their use as optical waveguides (optical fibers).
6214488 Polymer electrolyte membrane and process for the production thereof April 10, 2001
In order to produce a polymer electrolyte membrane from sulfonated, aromatic polyether ketone, an aromatic polyether ketone of the formula (I) ##STR1##in whichAr is a phenylene ring having p- and/or m-bonds,Ar' is a phenylene, naphthylene, biphenylene, anthrylene or another divalent arom
6194383 Lipopeptides from actinoplanes sp. with pharmacological action, process for their production and February 27, 2001
The invention relates to lipopeptides with very homologous amino-acid sequences but different fatty acid residues (lipid portion) which are synthesized by Actinoplanes sp. during fermentation and are released into the culture medium, to a process for isolating the lipopeptides from the
6191164 Sulfonamide-substituted chromans, processes for their preparation, their use as a medicament or February 20, 2001
Sulfonamide-substituted chromans, processes for their preparation, their use as a medicament or a diagnostic, and medicament comprising themChromans of the formula I ##STR1##and of the formula 1a ##STR2##having the meanings R(A), R(B), R(C) and R(1) to R(8) indicated in the claims ar
6177036 Process for formed article production by extrusion January 23, 2001
A plastic foam article 1 produced by extrusion, for example, a plastic foam sheet comprising homopolymers and copolymers of polycyclic olefins, contains at least 10% by volume of open cells 2, 4 which have a polyhedron-like shape and adjoin one another. The deformation-free opening o
6162420 Use of glyceryl triacetate for treating onychomycoses December 19, 2000
A nail varnish comprising glyceryl triacetate as an active compound and a water-insoluble film-forming agent is suitable for treatment of onychomycoses. If appropriate, the nail varnish can also additionally comprise antimycotic 1-hydroxy-2-pyridone derivatives.
6159900 Synergistic herbicidal agents December 12, 2000
When herbicides are applied, surfactants can affect the wettability of leaves of the plants and the effectiveness of the herbicides. According to the invention, a particular intensification of action is achieved when surfactants from the group comprising the C.sub.10 -C.sub.18 -alkyl
6159561 1,3-difluoronapthalene derivatives for liquid crystal mixtures December 12, 2000
1,3-Difluoronaphthalene derivatives of the formula (I)in whichB is ##STR1## and R.sup.1 (--A.sup.1 --M.sup.1).sub.a (--A.sup.2 --M.sup.2) and (--M.sup.3 --A.sup.3)(--M.sup.4 --A.sup.4)R.sup.2 denote mesogenic radicals are suitable as components for liquid-crystal mixtures, especi

 
 
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