| Patent Number |
Title Of Patent |
Date Issued |
| RE39449 |
Apparatus for cryopreservation and recovery of red blood cells |
December 26, 2006 |
| A system dynamically adjusts the delivery rate of a cryopreservation solution to red blood cells to permit freezing. The delivery rate is preferably determined according to an equation that maintains a linear change of red blood cell osmolarity over time so as to prevent osmolarity s |
| D609334 |
Support pole for holding solutions |
February 2, 2010 |
|
| D423095 |
Disposable blood bag set |
April 18, 2000 |
|
| D312128 |
Bowl body for centrifuge |
November 13, 1990 |
|
| 7601268 |
Continuous blood filtration and method of use |
October 13, 2009 |
| The invention is directed to a system for continuously filtering a blood product including whole blood or any of its component(s), erythrocytes, leukocytes, platelets and plasma either alone or in combination. The system includes a connector for receiving the blood product, a filter |
| 7452322 |
Rotor with elastic diaphragm for liquid-separation system |
November 18, 2008 |
| A rotor for collecting and centrifuging biological fluids in a range of volumes. The rotor includes an elastic impermeable diaphragm which defines at least a portion of a variable-volume processing chamber, where the fluid is centrifuged. The rotor includes a rigid mounting member, to |
| 7332125 |
System and method for processing blood |
February 19, 2008 |
| A system for filtering and processing blood that is simple to implement and that reduces the need for human intervention. The system may be used to collect red blood cells (RBCs). For such a system, a disposable set may be provided with an inlet port, an RBC container, a centrifuge rotor |
| 7055401 |
Closed method and system for the sampling and testing of fluid |
June 6, 2006 |
| A closed fluidic sampling system. The system includes a first port for receiving a sample of fluid and a sampling chamber in fluid communication with the first port. A a one-way valve allows fluid to flow from the first port towards the sampling chamber while preventing backflow of f |
| 6824506 |
Shaped diaphragm for a centrifuge system rotor |
November 30, 2004 |
| A shaped diaphragm as a part of a fluid processing disposable set acting as a centrifuge system rotor. The fluid processing disposable set has a variable-volume chamber and a fluid port. The shaped diaphragm defines a wall of the variable-volume chamber. The chamber is in fluid communica |
| 6709377 |
System and method for quick disconnect centrifuge unit |
March 23, 2004 |
| A centrifugal device. The centrifugal device includes two drive units (1, 22) , coaxially mounted and pivoting, devices (23-33) to drive the first (1) and the second (22) drive units, with a rotational speed ratio of 2/1 between each other, a circular centrifugal unit (2) equipped with a |
| 6705983 |
Compact centrifuge device and use of same |
March 16, 2004 |
| This device includes a centrifugal cup or bowl (2) rotating at the speed of 2.omega. around its revolving axis, a separation chamber (3) connected to the center of this cup or bowl (3) by three channels (4, 5, 6) integral to three flexible tubes (4a, 5a, 6a) forming open loops driven at |
| 6641552 |
Blood collection and separation system |
November 4, 2003 |
| A system compact enough to be located entirely beside the donor's chair, and able to process the blood while the donor is still resting in the chair after having donated the blood. The separated blood components (plasma and red blood cells) may be stored in their individual optimum e |
| 6632191 |
System and method for separating blood components |
October 14, 2003 |
| A system for collecting red blood cells (RBCs) and other blood components that reduces the need for human intervention. A disposable set is provided having a port, an RBC container, a centrifuge rotor having a variable total volume, and a filter, along with tubing connecting the port, th |
| 6629919 |
Core for blood processing apparatus |
October 7, 2003 |
| The invention is directed to a centrifugation bowl with a rotating core. The centrifugation bowl includes a rotating bowl body which defines a primary separation chamber. The core, which is generally cylindrically shaped and is disposed within the bowl body, defines a secondary separ |
| 6602179 |
Rotor with elastic diaphragm defining a liquid separating chamber of varying volume |
August 5, 2003 |
| A rotor for collecting and centrifuging biological fluids in a range of volumes. The rotor includes an elastic impermeable diaphragm which defines at least a portion of a variable-volume processing chamber, where the fluid is centrifuged. The rotor includes a rigid mounting member, to wh |
| 6558307 |
Method for collecting platelets and other blood components from whole blood |
May 6, 2003 |
| A method for collecting, from whole blood, platelets suspended in plasma is described. By centrifuging the blood at a high enough rotational speed, the platelets are separated from the plasma and the red blood cells. In a preferred embodiment, some of the plasma is removed while the cent |
| 6464624 |
Blood processing method and apparatus using a centrifugation bowl with filter core |
October 15, 2002 |
| The invention is directed to blood processing method and apparatus utilizing a centrifugation bowl with a filter core disposed within the bowl. The centrifugation bowl includes a rotating bowl body defining an enclosed separation chamber. A generally cylindrical filter core is dispos |
| 6440372 |
Apparatus for cryopreservation and recovery of red blood cells |
August 27, 2002 |
| A system dynamically adjusts the delivery rate of a cryopreservation solution to red blood cells to permit freezing. The delivery rate is preferably determined according to an equation that maintains a linear change of red blood cell osmolarity over time so as to prevent osmolarity s |
| 6402702 |
Automatic whole blood collection system |
June 11, 2002 |
| A whole blood collection system includes an automated pump/control unit and an accompanying disposable blood set. When combined and connected to a source of anticoagulant, these elements allow automatic priming of the blood set with anticoagulant and automatic collection of anticoagulate |
| 6267925 |
Method for cryopreservation and recovery of red blood cells |
July 31, 2001 |
| A system dynamically adjusts the delivery rate of a cryopreservation solution to red blood cells to permit freezing. The delivery rate is preferably determined according to an equation that maintains a linear change of red blood cell osmolarity over time so as to prevent osmolarity s |
| 6113554 |
Automatic whole blood collection system |
September 5, 2000 |
| A whole blood collection system includes an automated pump/control unit and an accompanying disposable blood set. When combined and connected to a source of anticoagulant, these elements allow automatic priming of the blood set with anticoagulant and automatic collection of anticoagulate |
| 6026684 |
Active donor hand gripper for use in a blood collection apparatus |
February 22, 2000 |
| An active hand gripper for use in a blood drawing apparatus provides a tactile signal to a blood donor reminding the donor to periodically squeeze the hand gripper, thereby increasing donor venous pressure and the related blood flow rate from the donor into the blood drawing apparatus. |
| 5971948 |
Apparatus for collection, washing, and reinfusion of shed blood |
October 26, 1999 |
| An integrated, vacuum-driven shed blood processing system that collects, dilutes, filters and washes postoperatively shed blood and concentrates red blood cells for reinfusion to the patient. The location of the centrifuge bowl between the surgical site and the vacuum source used to |
| 5954971 |
Pumped-filter blood-processing apparatus and methods |
September 21, 1999 |
| Automated filtration of whole blood or blood components is accomplished in a manner that ensures consistent flow or pressure characteristics through the filter. A feedback circuit monitors pressure in the vicinity of the filter inlet and controls operation of a fluid pump that sends one |
| 5882289 |
Centrifuge bowl with improved core structure |
March 16, 1999 |
| A centrifuge bowl suitable for separating blood components, in particular concentrated red blood cells. A centrifuge bowl 10 comprises a core 14 having an annular portion 50A and a cylindrical outer wall 50. Annular portion 50A has a thick wall for minimizing the holdup volume of blood |
| 5783093 |
Blood cell concentrates using a single solution for anticoagulation and preservation |
July 21, 1998 |
| A method for preparing red blood cell concentrates uses a single additive solution composition having a reduced citrate concentration both for anticoagulation of whole blood and for preserving red blood cells in storage. |
| 5769811 |
Blood-processing machine system |
June 23, 1998 |
| A multiprotocol blood-processing machine and disposable units for use therewith. The disposable units generally comprise a centrifuge bowl for separating whole blood into blood constituents, an inlet tube for conveying blood into the bowl, an outlet tube for conveying the blood const |
| 5658231 |
Mechanism for securing a separation bowl to a mechanical chuck |
August 19, 1997 |
| A centrifugal chuck comprising a chuck housing and a plurality of fingers pivotally mounted around the outer perimeter of the chuck housing. Each finger includes a tip, adapted to receive the base portion of a separation bowl. The fingers are mounted to the chuck housing so that the tips |
| 5643193 |
Apparatus for collection washing and reinfusion of shed blood |
July 1, 1997 |
| An integrated, vacuum-driven shed blood processing system that collects, dilutes, filters and washes postoperatively shed blood and concentrates red blood cells for reinfusion to the patient. The location of the centrifuge bowl between the surgical site and the vacuum source used to |
| 5637082 |
Adaptive apheresis apparatus |
June 10, 1997 |
| Automated apheresis apparatus and methods avoid unneeded collection and return of blood components. An operator "dials in" a desired amount of one or more blood components, whereupon the invention calculates the number of cycles necessary to achieve the target and directly implements an |
| 5634893 |
Autotransfusion apparatus |
June 3, 1997 |
| An autotransfusion apparatus for collecting salvaged blood includes an upper chamber for collecting blood and a lower chamber for receiving blood from the upper chamber. The upper chamber is subjected to a vacuum to withdraw blood from a patient. Particles and lipids are removed from the |
| 5607579 |
Apheresis apparatus for separating an intermediate density component from whole blood |
March 4, 1997 |
| An apheresis apparatus for increasing the purity and yield of platelets separated from donated whole blood by centrifugation incorporates a centrifuge for separating whole blood into lower, intermediate, and higher density components. The centrifuge has inlet and outlet ports in selectiv |
| 5514095 |
Apparatus for heating, filtering and eliminating gas from biological fluids |
May 7, 1996 |
| The present invention provides an apparatus for heating, filtering and eliminating gas from biological fluids. The apparatus includes a heat exchanger for heating biological fluids coaxially positioned within a filter unit. The filter unit receives heated fluid from the heat exchanger |
| 5514070 |
Plural collector centrifuge bowl for blood processing |
May 7, 1996 |
| A centrifuge bowl for separating whole blood into less dense and more dense components and for collecting both less dense and more dense components without stopping bowl rotation. The fluid pathway from an inlet port to a separation chamber comprises an inlet tube and an introduction pas |
| 5505683 |
Centrifuge bowl gripping apparatus having a retaining arm with a stationary jaw and a moveable j |
April 9, 1996 |
| An apparatus for gripping a centrifuge bowl includes a single pivoting retaining arm having a stationary jaw. The retaining arm is capable of pivoting into and out of position such that the centrifuge bowl can be loaded and unloaded. A moveable jaw pivots about the retaining arm to lock |
| 5494592 |
Apheresis apparatus and method |
February 27, 1996 |
| An apheresis apparatus and method is disclosed for increasing the purity and yield of platelets separated from donated whole blood in a centrifuge. The whole blood in the centrifuge is diluted by recirculating fluid, such as plasma or saline, at a first flow rate, to mix with further wit |
| 5478479 |
Two-stage cell wash process controlled by optical sensor |
December 26, 1995 |
| A method of washing salvaged blood includes separating higher density blood components from lower density blood components within a rotating centrifuge bowl. The separated blood components are washed with wash solution to remove free hemoglobin (Hgb), anticoagulant, cellular debris a |
| 5458459 |
Centrifugal blood pump with impeller blades forming a spin inducer |
October 17, 1995 |
| A centrifugal pump for pumping biological fluids such as blood includes a housing which defines a pumping chamber. The pumping chamber encloses an impeller comprised of a spindle for rotation about a spindle axis and a plurality of blades positioned such that each inner blade end is |
| 5405308 |
Disposable centrifuge rotor and core for blood processing |
April 11, 1995 |
| An improved centrifuge rotor formed of a bowl body and core for blood processing applications, such as cell washing or pheresis, is described. A tubular core adapted to rotate with the rotor defines a processing region between the core and the interior of the bowl body. A plurality of |
| 5387187 |
Red cell apheresis method |
February 7, 1995 |
| The present invention provides an apheresis apparatus and method for separating blood. A phlebotomy needle draws anticoagulated whole blood from a donor into a separation chamber. The separation chamber separates plasma from higher density blood components. The plasma is displaced to a |
| 5387088 |
Peristaltic pump tube loading assembly |
February 7, 1995 |
| A peristaltic pump assembly for easy loading includes a pump housing having a curved surface. A stationary tubing manifold from which a loop of tubing extends is positioned in line with the curved surface. A pump rotor rotatable about an axis is positioned adjacent to the curved surface. |
| 5311908 |
Blood processing method and apparatus with disposable cassette |
May 17, 1994 |
| A fluid flow apparatus includes a peristaltic pump rotor mounted to a deck module assembly. A disposable software set is provided which includes a cassette which has a primary flexible tube and a pump platen adjacent to which the primary flexible tube resides. Tubing with blood processin |
| 5273517 |
Blood processing method and apparatus with disposable cassette |
December 28, 1993 |
| A fluid flow apparatus includes a peristaltic pump rotor mounted to a deck module assembly. A disposable software set is provided which includes a cassette which has a primary flexible tube and a pump platen adjacent to which the primary flexible tube resides. Tubing with blood processin |
| 5100372 |
Core for blood processing apparatus |
March 31, 1992 |
| An improved core member for a centrifuge bowl is described in which a plurality of small size circular openings are formed in the core member between a toroidal blood cell separation chamber and a collection chamber to provide fluid communication therebetween for collection of blood |
| 5045048 |
Rotary centrifuge bowl and seal for blood processing |
September 3, 1991 |
| A seal for a blood processing centrifuge bowl which is formed of a dynamic rotary seal and a static seal. The dynamic rotary seal is formed of an upper graphite or carbon non-rotating ring member and a lower two-piece rotatable ring member formed of a ceramic bearing surface bonded by |
| 4983158 |
Plasmapheresis centrifuge bowl |
January 8, 1991 |
| An improved disposable plasmapheresis centrifuge bowl is described comprising a rotary seal enclosing an aperture in a one-piece seamless bowl body through which various core members may be inserted. |
| 4946434 |
Disposable manifold and valve |
August 7, 1990 |
| A disposable manifold and valve for fluid processing are claimed in which a manifold provides a plurality of sterile paths for directing the flow of fluids. A rotatable valve employs a cam to control the flow of fluids through the manifold. The valve and manifold system are suited for th |
| 4943273 |
Disposable centrifuge bowl for blood processing |
July 24, 1990 |
| An improved disposable blood processing centrifuge bowl is described comprising a rotary seal enclosing an aperture in a bowl body through which a two-piece core assembly is inserted. |
| 4889524 |
Portable centrifuge apparatus |
December 26, 1989 |
| A portable centrifuge apparatus for use with a centrifuge bowl having a seamless, unitary blow molded bowl body for the separation of blood into less dense and more dense components. A light weight, hand-held cabinet houses the centrifuge, and auxiliary equipment such as blood pumps, |
| 4871462 |
Enhanced separation of blood components |
October 3, 1989 |
| A method of separating blood plasma from particles including blood cells, in the blood, includes the steps:(a) providing a membrane with holes therethrough of a size to pass the particulate, and supplying blood to one side of the membrane,(b) moving the membrane at sufficiently high velocity |
