| Patent Number |
Title Of Patent |
Date Issued |
| RE34606 |
Modified enzymes and methods for making same |
May 10, 1994 |
| A cloned subtilsin gene has been modified at specific sites to cause amino acid substitutions at certain spots in the enzyme. The modified enzyme, preferably produced by Bacillus, is useful in combination with detergents. |
| 5441882 |
Method for preparing modified subtilisins |
August 15, 1995 |
| There are described methods for making mutant subtilisins, the methods comprising obtaining a DNA fragment from a Bacillus subtilisin and introducing a mutation into the fragment by substituting at least one amino acid, transforming a suitable host cell with the mutated DNA, recoveri |
| 5411873 |
Process for producing heterologous polypeptides |
May 2, 1995 |
| Processes for producing various heterologous polypeptides which when expressed are either incorrectly processed and hence asssociated with the surface of the host cell or are not processed to mature form. More specifically, processes for the production of heterologous non-human carbo |
| 5389536 |
Lipase from Pseudomonas mendocina having cutinase activity |
February 14, 1995 |
| A substantially enzymatically pure hydrolase is provided which is secreted by and isolatable from Pseudomonas mendocina ATCC 53552. Cloning the gene expressing the hydrolase into a suitable expression vector and culturing, such as fermenting the E. coli strain JM101 harboring a plasmid d |
| 5378621 |
Killing cells without lysis in a method for enzyme recovery from a fermentation broth |
January 3, 1995 |
| This invention provides a method for killing fungal cells without lysing in fermentation processes in order to prepare the fermentation mixture for processing to recover or extract an extracellularly expressed enzyme from the fermentation mixture. A preferred method of this invention com |
| 5346823 |
Subtilisin modifications to enhance oxidative stability |
September 13, 1994 |
| There are provided methods for making a mutant Bacillus subtilisin having altered oxidative stability, the methods comprising obtaining DNA fragment consisting of a region coding for a Bacillus subtilisin, and introducing a mutation into said DNA fragment such that the mutation is introd |
| 5316941 |
Non-human carbonyl hydrolase mutants, DNA sequences and vectors encoding same and hosts transfor |
May 31, 1994 |
| There are described certain DNA sequences which encode subtilisins wherein the amino acid sequence of such substilisins has been modified at a position equivalent to +225 in Bacillus amyloliquefaciens, such that an amino acid selected from the group consisting of alanine, leucine, me |
| 5310675 |
Procaryotic carbonyl hydrolases |
May 10, 1994 |
| Recombinant host bacteria and plasmids for making the bacteria using recombinant DNA techniques are described. The plasmids contain DNA coding for subtilisin with an amino acid substitution. Expression of the plasmid DNA results in production of a modified subtilisin. |
| 5264366 |
Protease deficient bacillus |
November 23, 1993 |
| There are described, normally sporulating mutant Bacillus strain(s) which produce no detectable proteolytic activity during any phase of its growth. The absence of detectable proteolytic activity is due to the deletion of one or more codons specifying the mature subtilisin protease and t |
| 5155033 |
Subtilisins modified at position 225 resulting in a shift in catalytic activity |
October 13, 1992 |
| There are described certain subtilisins wherein the amino acid sequence of such subtilisins has been modified at a position equivalent to +225 in Bacillus amyloliquefaciens, such that an amino acid selected from the group consisting of alanine, leucine, methionine, glutamine, valine, and |
| 4981611 |
Cutinase cleaning compositions |
January 1, 1991 |
| This invention relates to cleaning compositions and methods for using them. Particularly, the invention relates to compositions comprising a surfactant and a cutinase enzyme. A preferred cutinase is derived from Pseudomonas putida ATCC 53552. Excellent cleaning is obtained with a sur |
| 4927644 |
Preferential entrainment of enzymes in cheese curds |
May 22, 1990 |
| The invention relates to a novel method for preferentially entraining a lipase or protease substantially into cheese curds when making curds and whey. An insoluble enzyme particle size of at least about 0.20 microns is selected or formed, and upon curd formation the insoluble particle wi |
| 4795101 |
Use of cellulase in a method of wet milling a starch-containing grain |
January 3, 1989 |
| The invention relates to a method of milling grain, especially corn, comprising cleaning the grain, steeping the grain in water to soften it, and then milling the grain with a cellulase enzyme. |
| 4760025 |
Modified enzymes and methods for making same |
July 26, 1988 |
| A cloned subtilisin gene has been modified at specific sites to cause amino acid substitutions at certain spots in the enzyme. The modified enzyme, preferably produced by Bacillus, is useful in combination with detergents. |
| 4749511 |
Contact lens cleaning solutions containing endoproteinase lys-C |
June 7, 1988 |
| Contact lens cleaning compositions and a method which comprises treating soft contact lenses with general purpose proteases in combination with endoproteinase lys-C are effective in dissolving away and hydrolyzing lysozyme, the major protein component of tears. |
| 4726954 |
Lipolytic enzyme derived from a aspergillus microorganism having an accelerating effect on chees |
February 23, 1988 |
| The present invention relates to a novel lipolytic enzyme derived from a novel Aspergillus microorganism. Cheese aged in the presence of a low concentration of this lipolytic enzymes ripens faster than with conventional lipolytic enzymes and without any associated rancidity. |
| 4721676 |
Novel thermophile isolate having thermostable hydrolytic activity |
January 26, 1988 |
| This application represents an invention based upon the discovery of a novel thermophilic organism, its isolation from natural source and to the unique thermostable hydrolytic activity produced by this bacterium, this activity being useful for industrial purposes. |
| 4716911 |
Method for protein removal from tobacco |
January 5, 1988 |
| An improved process for removing insoluble nitrogen-containing compounds from cured tobacco uses alkali or a combination of protease and nonprotease depolymerase, rather than simple protease extraction.The method of the invention is more efficient and results in a more effective extracti |
| 4636468 |
Lipolytic enzyme derived from a aspergillus microorganism having an accelerating effect on chees |
January 13, 1987 |
| The present invention relates to a novel lipolytic enzyme derived from a novel Aspergillus microorganism. Cheese aged in the presence of a low concentration of this lipolytic enzymes ripens faster than with conventional lipolytic enzymes and without any associated rancidity. |
| 4618579 |
Raw starch saccharification |
October 21, 1986 |
| A multi-step process is provided for solubilizing and saccharifying granular starch slurries of between 20 and 60% d.s. starch. In a first step, an enzyme mixture exhibiting raw starch hydrolyzing activity is added to the slurry and maintained in contact therewith until at least a su |
