| Patent Number |
Title Of Patent |
Date Issued |
| 7592478 |
Ligand antagonists of RAR receptors and pharmaceutical/cosmetic applications thereof |
September 22, 2009 |
| Novel ligand antagonists of the RAR receptors have the following structural formula (I): ##STR00001## in which A is a CH.sub.2, CHOH, C.dbd.O or C.dbd.N--OH radical or a sulfur or selenium atom; B is a radical selected from among those of formulae (a) to (f): ##STR00002## and Ar is |
| 7582663 |
Biaromatic compounds which activate PPAR.gamma. type receptors and cosmetic/pharmaceutical compo |
September 1, 2009 |
| Novel biaromatic compounds having the structural formula (I) below: ##STR00001## are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases |
| 7579377 |
Administration of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid for the treatment of derm |
August 25, 2009 |
| Dermatological disorders having an inflammatory or proliferative component are treated with pharmaceutical compositions containing on the order of 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthanoic acid (adapalene) or salt thereof, formulated into pharmaceutically accept |
| 7517907 |
Pharmaceutical/cosmetic compositions comprising a novel RARbeta receptor-activating ligand |
April 14, 2009 |
| Novel ligand compounds having the structural formula (I): ##STR00001## and the salts and optical/geometrical isomers thereof are suited for formulation into pharmaceutical compositions useful in human or veterinary medicine, or, alternatively, into cosmetic compositions. |
| 7498461 |
Method for the preparation of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid |
March 3, 2009 |
| A novel method for preparing 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid includes a Suzuki reaction between 3-adamantyl-4-methoxyphenylboronic acid of formula (II): ##STR00001## and 6-bromo-2-naphthoic acid of formula (III): ##STR00002## |
| 7468457 |
Ligand inhibitors of the RAR receptors, process for preparing same and therapeutic/cosmetic appl |
December 23, 2008 |
| Novel biaryl compounds having the structural formula (I): ##STR00001## are useful in a variety of pharmaceutical applications, whether human or veterinary, and also in cosmetics. |
| 7452878 |
Biaromatic compounds which activate PPAR.gamma. type receptors and cosmetic/pharmaceutical compo |
November 18, 2008 |
| Novel biaromatic compounds having the structural formula (I) below: ##STR00001## are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases |
| 7439396 |
Pharmaceutical/cosmetic compositions comprising novel ligands that activate RAR receptors |
October 21, 2008 |
| Novel ligand compounds that activate RAR receptors have the following structural formula (I): ##STR00001## and are suited for formulation into pharmaceutical compositions useful in human or veterinary medicine, or, alternatively, into cosmetic compositions. |
| 7396953 |
Angiogenesis inhibitors and pharmaceutical/cosmetic applications thereof |
July 8, 2008 |
| Novel derivatives of fumagalone have the general formula (I): ##STR00001## and are useful angiogenes is inhibitors; these can be formulated into pharmaceutical compositions suited for human or veterinary medicine, or can be formulated into cosmetic compositions. |
| 7348449 |
Ligand antagonists of RAR receptors and pharmaceutical/cosmetic applications thereof |
March 25, 2008 |
| Novel ligand antagonists of the RAR receptors have the following structural formula (I): ##STR00001## in which A is a CH.sub.2, CHOH, C.dbd.O or C.dbd.N--OH radical or a sulfur or selenium atom; B is a radical selected from among those of formulae (a) to (f): ##STR00002## and Ar is |
| 7326803 |
Ligand inhibitors of the RAR receptors, process for preparing same and therapeutic/cosmetic appl |
February 5, 2008 |
| Novel bicyclic compounds having the structural formula (I): ##STR00001## are useful in a variety of pharmaceutical applications, whether human or veterinary, and also in cosmetics. |
| 7319155 |
7,7-disubstituted (5H,9H)-6,8-dioxabenzocycloheptene compounds useful in the synthesis of non-st |
January 15, 2008 |
| Novel 7,7-disubstituted (5H,9H)-6,8-dioxabenzocycloheptene compounds having the structural formula (I): ##STR00001## are useful intermediates in the synthesis of non-steroidal derivatives of vitamin D. |
| 7312249 |
Vitamin D analogues |
December 25, 2007 |
| Novel biaromatic vitamin D analogues have the general formula (I): ##STR00001## and are suited for a wide variety of pharmaceutical applications, whether in human or veterinary medicine, and also for cosmetic applications. |
| 7307078 |
Polycyclic compounds which modulate PPAR.gamma. type receptors and cosmetic/pharmaceutical compo |
December 11, 2007 |
| Novel polycyclic compounds having the structural formula (I) below: ##STR00001## are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases |
| 7294639 |
Biaromatic ligand activators of PPAR.gamma. receptors |
November 13, 2007 |
| Novel pharmaceutical/cosmetic compositions contain at least one biaromatic ligand activator of a PPAR.gamma. receptor, such biaromatic ligand having the structural formula (I): ##STR00001## and are well suited, inter alia, for regulating and/or restoring skin lipid metabolism, for treat |
| 7285568 |
Biaromatic compounds which activate PPARgamma type receptors and cosmetic/pharmaceutical composi |
October 23, 2007 |
| Novel biaromatic compounds having the structural formula (I) below: ##STR00001## are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases |
| 7148245 |
Biphenyl derivatives substituted with an aromatic or heteroaromatic radical, and pharmaceutical |
December 12, 2006 |
| Compounds of formula (I): ##STR00001## in which: Ar represents an aromatic or a heteroaromatic radical optionally substituted, in particular, with an alkyl or a carboxyl group, R.sub.2 and R.sub.3 represent, in particular, H or alkyl, or R.sub.2 and R.sub.3, taken together, form a |
| 7125869 |
Polycyclic compounds which modulate PPAR.gamma. type receptors and cosmetic/pharmaceutical compo |
October 24, 2006 |
| Novel polycyclic compounds having the structural formula (I) below: ##STR00001## are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases |
| 7122564 |
Biaromatic ligand activators of PPAR.gamma. receptors |
October 17, 2006 |
| Novel pharmaceutical/cosmetic compositions contain at least one biaromatic ligand activator of a PPAR.gamma. receptor, such biaromatic ligand having the structural formula (I): ##STR00001## and are well suited, inter alia, for regulating and/or restoring skin lipid metabolism, for treat |
| 6849658 |
Biaromatic compounds and pharmaceutical and cosmetic compositions comprising them |
February 1, 2005 |
| The invention concerns bi-aromatic compounds of formula (I) in which Ar represents (a), Z being O or S, R.sub.1 is CH.sub.3, --CH.sub.2 --O--R.sub.6, --OR.sub.6 or --COR.sub.7 ; R.sub.2 is --OR.sub.8, --SR.sub.8 or a polyether radical if in the latter case R.sub.4 is C.sub.1 -C.sub.2 |
| 6818666 |
Bi-aromatic compounds linked via a heteroethylene radical, and pharmaceutical and cosmetic compo |
November 16, 2004 |
| Bi-aromatic compounds linked via a heteroethynylene radical are provided along with pharmaceutical and cosmetic compositions containing these compounds and methods for their use. |
| 6649612 |
Biphenyl derivatives substituted with an aromatic or heteroaromatic radical, and pharmaceutical |
November 18, 2003 |
| Compounds of formula (I): ##STR1##in which: Ar represents an aromatic or a heteroaromatic radical optionally substituted, in particular, with an alkyl or a carboxyl group, R.sub.2 and R.sub.3 represent, in particular, H or alkyl, or R.sub.2 and R.sub.3, taken together, form a 5- or |
| 6642273 |
Unsaturated derivatives at the 4-position of 6-tert-butyl-1,1-dimethylindane and their use in hu |
November 4, 2003 |
| An unsaturated derivative at the 4-position of 6-tert-butyl-1,1-dimethylindane corresponding to the following formula: ##STR1##in which: X represents: a divalent radical of formula: ##STR2##and Y represents a divalent radical of following formula: ##STR3## R.sub.1 represents |
| 6534545 |
Unsaturated derivatives at the 4-position of 6-tert-butyl-1,1-dimethylindane and their use in hu |
March 18, 2003 |
| 6-tert-Butyl-1,1-dimethylindane derivatives which are unsaturated in the 4-position of formula: ##STR1## X represents: (i) either a radical of formula: (a) ##STR2## and Y represents a radical of formula: (b) ##STR3## (ii) or a radical of formula: (c) ##STR4## and |
| 6441010 |
Bi-aromatic compounds linked via a heteroethynylene radical, and pharmaceutical and cosmetic com |
August 27, 2002 |
| Bi-aromatic compounds linked via a heteroethynylene radical are provided along with pharmaceutical and cosmetic compositions containing these compounds and methods for their use. |
| 6346546 |
Biaromatic compounds and pharmaceutical and cosmetic compositions comprising them |
February 12, 2002 |
| Biaromatic compounds connected by a propynylene or ailenylene bond, corresponding to the formula (I). ##STR1## |
| 6340495 |
Device including a chromophoric composition to be applied to the skin, a method of fabricating s |
January 22, 2002 |
| The invention relates to device making it possible to apply a chromophoric composition to the skin, said device including a chromophoric composition containing at least one chromophoric agent. The chromophoric composition is in the form of a layer of constant thickness bonded to one face |
| 6316009 |
Biphenyl derivatives substituted by an aromatic or heteroaromatic radical and pharamaceutical an |
November 13, 2001 |
| "Biphenyl derivatives substituted with an aromatic or heteroaromatic radical, and pharmaceutical and cosmetic compositions containing them" ##STR1##in which:Ar represents an aromatic or a heteroaromatic radical optionally substituted, in particular, with an alkyl or a carboxyl group,R.su |
| 6201019 |
Bi-aromatic compounds bound by a heteroethynylene radical and pharmaceutical and cosmetic compos |
March 13, 2001 |
| Bi-aromatic compounds linked via a heteroethynylene radical are provided along with pharmaceutical and cosmetic compositions containing these compounds and methods for their use. |
| 6180674 |
Unsaturated derivatives at the 4-position of 6-tert-butyl-1, 1- dimethylindane and their use in |
January 30, 2001 |
| 6-tert-Butyl-1,1-dimethylindane derivatives which are unsaturated in the 4-position of formula: ##STR1##X represents:(i) either a radical of formula: ##STR2##and Y represents a radical of formula: ##STR3##(ii) or a radical of formula: ##STR4##and Y represents either a radical of |
| 6103762 |
Bi-aromatic compounds and pharmaceutical and cosmetic compositions containing same |
August 15, 2000 |
| The invention concerns bi-aromatic compounds of formula (I) in which Ar represents (a), Z being O or S, R.sub.1 is --CH.sub.3, --CH.sub.2 --O--R.sub.6, --OR.sub.6 or --COR.sub.7 ; R.sub.2 is --OR.sub.8, --SR.sub.8 or a polyether radical if in the latter case R.sub.4 is C.sub.1 -C.sub |
