| Patent Number |
Title Of Patent |
Date Issued |
| RE38628 |
Pharmaceutical compositions |
October 19, 2004 |
| A method of treatment of a condition selected from the group comprising conjunctivitis, keratitis, `allergic eyes`, adenovirus infections, corneal homograft rejection, anterior uveitis, nasal polyps, vasomotor rhinitis, allergic manifestations of the nasopharynx, reversible obstructive a |
| D395706 |
Overcap for a nasal inhalation device |
June 30, 1998 |
|
| D348100 |
Medicament inhaler |
June 21, 1994 |
|
| D281402 |
Programmable multimeter housing |
November 19, 1985 |
|
| 6123924 |
Pressurized aerosol inhalation compositions |
September 26, 2000 |
| Pressurized aerosol inhalation composition consisting essentially of a liquefied hydrofluoroalkane, a powdered medicament dispersible to form a suspension in the liquefied hydrofluoroalkane, and polyvinylpyrrolidone present in a concentration of 0.00001 to 10% w/w. |
| 6109261 |
Powder inhaler with breath flow regulation valve |
August 29, 2000 |
| There is provided a device for the administration of an inhalation medicament, including a body defining a through-going air pathway having a longitudinal axis, an air inlet, an air outlet forming a mouthpiece, means for dispensing medicament into the pathway and air flow regulating mean |
| 5976436 |
Process for production of medicament formulations |
November 2, 1999 |
| A process for the production of compacted bodies of powdered medicament is disclosed, the process comprising the steps of:a) positioning expansible means along the longitudinal axis of the mold;b) placing loose powdered medicament in the mold; andc) expanding the expansible means perpendicularly |
| 5846521 |
Pressurized solvent-free drug aerosol compositions containing hydrofluorocarbon propellants |
December 8, 1998 |
| Pressurised aerosol compositions comprise a medicament, a hydrofluorocarbon propellant and a polyethoxylated surfactant, the compositions containing substantially no solvent, other than the propellant, capable of increasing the solubility of the surfactant in the propellant. The composit |
| 5787881 |
Inhalation device |
August 4, 1998 |
| A device for the administration of powdered inhalation medicament contained initially in a capsule having at least one aperture formed therein, comprising a swirl chamber (1) adapted to receive the medicament capsule; a mouthpiece (2) communicating with the swirl chamber (1) and separate |
| 5727546 |
Powder inhaler with breath flow regulation valve |
March 17, 1998 |
| There is provided a device for the administration of an inhalation medicament, including a body defining a through-going air pathway having a longitudinal axis, an air inlet, an air outlet forming a mouthpiece, means for dispensing medicament into the pathway and air flow regulating mean |
| 5682875 |
Aerosol device having a spout to prevent spray head blockage |
November 4, 1997 |
| An aerosol inhalation device suitable for use in association with a pressurized medicament container having a valve stem has a spray head adapted to receive the valve stem. The spray head has an outlet orifice of uniform diameter which is provided with a spout to prevent blockage of the |
| 5670167 |
Process for the production of medicament formulations |
September 23, 1997 |
| A medicament compact is produced by placing loose powdered medicament in a mould having a longitudinal axis where a mandrel is positioned along the longitudinal axis of the mould compressing the medicament when a force parallel to the longitudinal axis is applied. The frictional force be |
| 5628307 |
Medicament inhalation device and formulation |
May 13, 1997 |
| A device for the administration by inhalation of a medicament in powdered form comprises a medicament reservoir (3) and metering means for dispensing a dose of medicament from the reservoir (3), characterized in that the reservoir (3) comprises a compacted body of powdered medicament |
| 5615670 |
Powder inhaler with centrifugal force used to meter powder |
April 1, 1997 |
| A device for the administration by inhalation of a medicament in dry powder form comprises a medicament reservoir (9) and a medicament metering system (10) including a metering chamber (23) communicable with the reservoir (9), characterized in that the reservoir (9) is mounted in a housi |
| 5572024 |
Apparatus and method for isotopic ratio plasma mass spectrometry |
November 5, 1996 |
| The invention comprises a method and apparatus for inductively-coupled plasma mass spectrometry which is particularly suitable for the determination of isotopic ratios.In order to improve the precision of such determinations, the nozzle-skimmer type interface of the mass spectrometer is |
| 5561292 |
Mass spectrometer and electron impact ion source thereof |
October 1, 1996 |
| An enclosed ion source for generating substantially monoenergetic ions from a gaseous sample comprises a chamber into which the gaseous sample is introduced and which is substantially enclosed by a source block having two electron entrance apertures formed in it and by a source plate hav |
| 5560490 |
Pharmaceutical packaging with capsule sealing means |
October 1, 1996 |
| A medicament pack (1) comprising a base member (2) having a plurality of blisters (3) formed therein, each blister (3) being adapted to accommodate a medicament containing capsule (4), each capsule (4) being provided with at least one aperture (5) to permit medicament to be dispensed the |
| 5538999 |
Medicament inhalation device and formulation |
July 23, 1996 |
| A compacted body of powdered medicament for use in a device for the administration by inhalation of a medicament in powdered form. The compacted body is made by compressing a loose powder containing the medicament in powdered form under pressure to create sufficient structural integr |
| 5534998 |
Sample nebulizer and evaporation chamber for ICP and MIP emission or mass spectrometry and spect |
July 9, 1996 |
| The invention provides a nebulizer and spray chamber (3) for producing an aerosol (7) suitable for feeding into the plasma torch of an ICP or MIP emission or mass spectrometer. The aerosol (7) is subjected to rapid radiative heating (26) to evaporate the smaller droplets to dryness and |
| 5532170 |
Processing analytical reagents |
July 2, 1996 |
| A method of preparing functionalized particles including (a) treating an activated substrate (CPG) with a bifunctional cross-linking agent containing a cleavable bond so as to immobilize the cross-linking agent, (b) conjugating an activated particle (P) with the immobilized cross-lin |
| 5519049 |
Macrolides for the treatment of reversible obstructive airways diseases |
May 21, 1996 |
| Compositions comprising certain macrolides are disclosed which are useful in methods for the treatment of reversible obstructive airway diseases, particularly asthma. |
| 5514868 |
Reducing interferences, in plasma source mass spectrometers |
May 7, 1996 |
| A method and apparatus for determining the elemental composition of a sample (1) by plasma mass spectroscopy comprises introducing a said sample (1) into an inductively-coupled or microwave-induced plasma formed in an inert gas to generate atomic ions from the elements present in it; pas |
| 5506414 |
Charged-particle analyzer |
April 9, 1996 |
| The invention provides apparatus and methods for investigating a small selected area of the surface of a specimen. The specimen is irradiated by a primary beam of X-rays or electrons to cause it to emit electrons. These are collected by a novel electron-optical arrangement and are used t |
| 5490497 |
Inhalation devices with a reduced risk of blockage |
February 13, 1996 |
| An elastomeric cap for use in an aerosol inhalation device is disclosed. The cap prevents blockage and the buildup of accretions of medicament on the valve stem of the inhalation device and shields the valve stem from the breath of a user of the inhalation device. |
| 5482946 |
Medicament inhalation device and formulation |
January 9, 1996 |
| A compacted body of powdered medicament for use in a device for the administration by inhalation of a medicament in powdered form. The compacted body is made by compressing a loose powder containing the medicament in powdered form under pressure to create sufficient structural integr |
| 5478756 |
Chemical sensor for detecting binding reactions |
December 26, 1995 |
| A chemical sensor includes a piezoelectric support (1) capable of supporting a shear horizontal wave provided on its surface with an electrode (2,3). The sensor is characterized in that the surface of the piezoelectric support (1) including the region bearing the electrode (2,3) is c |
| 5475023 |
Aqueous pharmaceutical formulations of sodium cromoglycate |
December 12, 1995 |
| A pharmaceutical formulation comprising a substantially clear aqueous solution having a viscosity of less than 10 mPa.s containing 3.5 to 5% w/v of 1,3-bis(2-carboxychromon-5-yloxy)-propan-2-ol, or a pharmaceutically acceptable salt thereof, as active ingredient and glycerol, the con |
| 5471059 |
Multiple-detector system for detecting charged particles |
November 28, 1995 |
| A multiple charged-particle detector system includes a plurality of charged-particle detector assemblies (10-12) which are each made up of a first arm (19-22) and a second arm (24-27) extending at an angle to each other. Charged particles (4-7) enter an aperture (14-18) at the entrance |
| 5468620 |
Methods and device for glycosylation analysis |
November 21, 1995 |
| Methods of glycosylation analysis are described in which a sample containing one or more specific oligosaccharide(s) (the analyte) is contacted with a surface on which is immobilized a glycosidase specific for the analyte and/or a specific binding partner for a product of the action |
| 5451783 |
Charged-particle analyser |
September 19, 1995 |
| A charged particle analyzer which irradiates a specimen and analyzes charged particles emitted therefrom, for example a photo electron spectrometer, having a flood-source which emits charged particles to neutralize the charge which develops on a specimen. The analyzer is provided wit |
| 5443833 |
Pharmaceutical compositions |
August 22, 1995 |
| A method of treatment of a condition selected from the group comprising conjunctivitis, keratitis, `allergic eyes`, adenovirus infections, corneal homograft rejection, anterior uveitis, nasal polyps, vasomotor rhinitis, allergic manifestations of the nasopharynx, reversible obstructive a |
| 5434663 |
Analytical device |
July 18, 1995 |
| A sensor, particularly a resonant optical biosensor based on the principle of frustrated total reflection, includes an optical structure comprising: a) a cavity layer (3) of transparent dielectric material of refractive index n.sub.3, b) a dielectric substrate (1) of refractive index n.s |
| 5428044 |
Anti-inflammatory 4-aminophenyl derivatives |
June 27, 1995 |
| There are disclosed compounds of the formula (I): ##STR1## in which the variables R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, and X are defined in the specification. The compounds are useful as pharmaceuticals, especially as anti-inflammatory agents. |
| 5415842 |
Surface plasmon resonance analytical device |
May 16, 1995 |
| A long-range SPR sensor includes: (a) a source of electromagnetic radiation, (b) an optical structure including a block of material transparent to the electromagnetic radiation, a spacer layer of dielectric material, a metallic layer, and a sensitive layer capable of reaction with a |
| 5406608 |
X-ray analysis apparatus |
April 11, 1995 |
| A device for performing both elemental and structural analysis of a crystalline sample, comprising a polychromatic x-ray source (11); a mounting means (15) for mounting the sample so that it is illuminated with x-rays; one or more fluorescence channels (17), able to select x-rays of a |
| 5384461 |
Process for the manufacture of a multipolar elongate-electrode lens or mass filter |
January 24, 1995 |
| The method includes the steps of assembling one or more blanks (1) in supporting means (2, 3) so that the or each blank occupies at least the space to be occupied by elongate electrodes and, without disturbing the position of the blanks relative to said supporting means, removing mat |
| 5384316 |
4,16-diazatetracyclo[23.3.1.1.Hu 14,17=b . 0 Hu 4,9 triaconta-16,19-diene-2,3,10-trione derivati |
January 24, 1995 |
| Compounds of formula (I) are provided, wherein R.sup.1 represents OH or OCH.sub.3 ; R.sup.2 represents OH or H; R.sup.3 represents methyl, ethyl, propyl or allyl; X represents O, (H,OH) or (H,H); m represents 0 or 1; n represents 1 or 2; and pharmaceutically acceptable derivatives thereo |
| 5383019 |
Inductively coupled plasma spectrometers and radio-frequency power supply therefor |
January 17, 1995 |
| The invention provides methods and apparatus for atomic emission spectroscopy and for mass spectrometry which make use of an inductively coupled radio-frequency plasma torch. A radio-frequency power supply supplies energy to a plasma induction coil via reflectometer means and a match |
| 5376787 |
Mass spectrometer with adjustable aperture mechanism |
December 27, 1994 |
| In a mass spectrometer, an aperture defining a beam path to a particle detector (4) is defined by a fixed aperture (5) and a cover (6) mounted on respective carriage assemblies (50,49) running along a beam 46. When a shaft (36) drives carriage (50), a rod (22) on carriage (49) is engaged |
| 5376663 |
Macrocyclic compounds |
December 27, 1994 |
| Compounds of formula (I), in which [R.sup.1 and R.sup.2 ], [R.sup.3 and R.sup.4 ] and [R.sup.5 and R.sup.6 ] represent a carbon-carbon bond or two hydrogen atoms; R.sup.2 additionally represents alkyl; R.sup.7, R.sup.8 and R.sup.9 represent groups including H or OH, R.sup.10 has various |
| 5374563 |
Surface plasmon resonance device and method of determining biological, biochemical, or chemical |
December 20, 1994 |
| A sensor based on the technique of surface plasmon resonance (SPR) comprises an SPR device, a source of electromagnetic radiation from which radiation can be directed onto the device, and a detector to measure the intensity of radiation reflected from the SPR device. The electromagnetic |
| 5369035 |
Method and apparatus for analytical sample preparation |
November 29, 1994 |
| In the elemental analysis of an analyte present in a sample by optical or mass spectrometry, a nebulizer sprays the liquid sample into a chamber which has a wall transparent to infra-red radiation. Infra-red radiation from a heater external to the chamber is focused on to the droplets of |
| 5356631 |
Pharmaceutical composition |
October 18, 1994 |
| Particulate nedocromil sodium with a mass median diameter of from 5 to 10 .mu.m is useful as a medicament for inhalation.The particulate nedocromil sodium of the invention is particularly advantageous in that its dispersion, i.e. the proportion of particles which are capable of penetrati |
| 5354988 |
Power supply for multipolar mass filter |
October 11, 1994 |
| A quadrupole mass filter (1) includes a controllable RF oscillator (7) which follows any drift in the resonant frequency of a resonant circuit means (8), this circuit means (8) amplifying an alternating RF potential from the oscillator (7) and supplying it to the filter electrodes (2, 3, |
| 5352893 |
Isotopic-ratio plasma source mass spectrometer |
October 4, 1994 |
| An isotopic-ratio mass spectrometer comprises an r.f. or microwave induced plasma ion source (1, 2, 3), an electrostatic ion-energy analyzer (75), a magnetic sector ion-momentum analyzer (82) wherein ions are dispersed at a first potential according to their mass-to-charge ratios, and tw |
| 5349944 |
Inhalation devices with a reduced risk of blockage |
September 27, 1994 |
| An aerosol inhalation device, having a mouthpiece (12) and a canister (15) of pressurized hygroscopic medicament, the canister (15) being fitted at one end with a dispensing metering valve; wherein a protective barrier (19) is provided between the dispensing metering valve and the mouthp |
| 5348978 |
Angiotensin converting enzyme inhibitors |
September 20, 1994 |
| Angiotensin converting enzyme inhibitors have the formula Z(CH.sub.2).sub.n CHR.sub.1 COOCHR.sub.2 COOHin which Z is --SR.sub.3, --COCHR.sub.4 NHCOR.sub.5, ##STR1## or --NHCHR.sub.7 COOH, R.sub.4, R.sub.5, R.sub.6, and R.sub.7, which may be the same or different, are each phenyl or |
| 5347125 |
Mass spectrometer having means for observing the radiation emitted when ions collide with a targ |
September 13, 1994 |
| A collision cell for observing the emission spectrum of ions. The substantially enclosed collision cell (8) is bounded by a wall (46), the wall having an entrance aperture (47) and an exit aperture (29) through which an ion beam (5) may be passed to traverse the collision cell, and h |
| 5341800 |
Medicament inhalation device and formulation |
August 30, 1994 |
| A method of compacting and administering a powdered inhalation medicament for use in an inhalation device includes compacting a body of loosely powdered inhalation medicament such that the degree of compaction is sufficient to hold the body together solely due to the force of compaction |
| 5334374 |
Pharmaceutical compositions containing pentamidine |
August 2, 1994 |
| Pharmaceutical compositions suitable for administration by inhalation and containing pentamidine, or pharmaceutically acceptable salt thereof, in powder form. Such compositions include pressurized aerosol compositions and nonpressurized power compositions. Also described is finely divide |
