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Epitomics, Inc. Patents
Assignee:
Epitomics, Inc.
Address:
Burlingame, CA
No. of patents:
4
Patents:




Patent Number Title Of Patent Date Issued
7462697 Methods for antibody engineering December 9, 2008
The invention provides a method for identifying positions of an antibody that can be modified without significantly reducing the binding activity of the antibody. In many embodiments, the method involves identifying a substitutable position in a parent antibody by comparing its amino aci
7431927 TNF.alpha.-neutralizing antibodies October 7, 2008
The invention provides monoclonal antibodies that neutralize TNF.alpha. activity. The monoclonal antibodies may be rabbit monoclonal antibodies or monoclonal antibodies having CDR regions derived from those rabbit monoclonal antibodies. In certain embodiments, the monoclonal antibodies
7429487 Fusion partner for production of monoclonal rabbit antibodies September 30, 2008
The invention provides a rabbit-derived immortal B-lymphocyte capable of fusion with a rabbit splenocyte to produce a hybrid cell that produces an antibody. The immortal B-lymphocyte does not detectably express endogenous immunoglobulin heavy chain and may contain, in certain embodim
7402409 Cell fusion method July 22, 2008
The invention provides methods for fusing a first cell with a second cell to form a hybrid cell. The methods involve incubating a first parental cell producing a first partner of a fusogenic binding partner pair on its surface with a second parental cell producing a second partner of the

 
 
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