| Patent Number |
Title Of Patent |
Date Issued |
| RE40033 |
Process for preparing 2-methyl-thieno-benzodiazepine |
January 22, 2008 |
| 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno-[2,3-b][1,5]benzodiazepine, or an acid salt thereof, has pharmaceutical properties, and is of particular use in the treatment of disorders of the central nervous system. The compound has the following structure: ##STR00001## |
| RE39071 |
Anhydro-and isomer-a-21978c cyclic peptides |
April 18, 2006 |
| Two new groups of A-21978C cyclic peptides, anhydro- and isomer-A21978C peptide derivatives, have antibacterial activity and are useful as intermediates. The two groups are prepared via transpeptidation of the parent cyclic peptides. Pharmaceutical formulations containing the new pep |
| RE39050 |
Methods of use for inhibiting bone loss and lowering serum cholesterol |
March 28, 2006 |
| A method of inhibiting bone loss or resorption, or lowering serum cholesterol, comprising administering to a human in need thereof a compound having the formula ##STR00001## or a pharmaceutically acceptable salt or solvate thereof, in a low dosage amount. Also encompassed by the in |
| RE39049 |
Methods for inhibiting bone loss |
March 28, 2006 |
| The current invention provides methods and pharmaceutical formulations that are useful for inhibiting the loss of bone. These methods and formulations can be used without the associated adverse effects of estrogen therapy, and thus serve as an effective and acceptable treatment for o |
| RE39030 |
Fluoxetine enteric pellets and methods for their preparation and use |
March 21, 2006 |
| A superior enteric formulation of the antidepressant drug, fluoxetine, is in the form of enteric pellets of which the enteric layer comprises hydroxypropylmethylcellulose acetate succinate. |
| RE38968 |
Methods for inhibiting bone loss using 6-hydroxy-2-(4-hydroxyphenyl)-benzo- [b]thien-3-yl-4-[2-(p |
February 7, 2006 |
| The current invention provides a method useful for inhibiting the loss of bone using 6-hydroxy-2-(4-hydroxyphenyl)-benzo(B)-thien-3-yl-4[2-piperidi- n-1-ethoxyphenol]methanone hydrochloride. |
| RE37971 |
Selective acylation of epsilon-amino groups |
January 28, 2003 |
| The present invention relates to the acylation of proteins. More particularly, the invention relates to a one-step process for selectively acylating the free .epsilon.-amino group of insulin, insulin analog, or proinsulin in the presence of a free .alpha.-amino group. |
| RE37806 |
Method of using eukaryotic expression vectors comprising the BK virus enhancer |
July 23, 2002 |
| The present invention is a method of using the BK enhances in tandem with a eukaryotic promoter to promote transcription of DNA that encodes a useful substance. The method of the present invention requires the presence of the E1A gene produce for maximum expression of the useful substanc |
| RE37720 |
Method of using eukaryotic expression vectors comprising the BK virus enhancer |
May 28, 2002 |
| The present invention is a method of using the BK enhancer in tandem with a eukaryotic promoter to promote transcription of DNA that encodes a useful substance. The method of the present invention requires the presence of the E1A gene product for maximum expression of the useful substanc |
| RE34875 |
Method of selecting recombinant DNA-containing streptomyces |
March 14, 1995 |
| A novel method of selecting Streptomyces recombinant DNA-containing host cells and vectors useful in the method are described. The vectors confer tylosin resistance to sensitive Streptomyces host cells and thus provide a convenient method of selecting Streptomyces transformants. The nove |
| RE33300 |
Oxiranes |
August 14, 1990 |
| There are described compounds of formula ##STR1## in which n is 0, 1 or 2, R.sup.1 is a hydrocarbyl group optionally substituted with an optionally substituted phenyl group and containing from 5 to 30 carbon atoms, R.sup.2 is optionally substituted phenyl or C.sub.1-10 alkyl opti |
| RE32455 |
A-21978 antibiotics and process for their production |
July 7, 1987 |
| Antibiotic A-21978C complexes, in particular the A-21978C complex, comprising microbiologically active, related factors, C.sub.0, C.sub.1, C.sub.2, C.sub.3, C.sub.4, and C.sub.5. A-21978 complex and A-21978C complex are produced by submerged aerobic fermentation of Streptomyces roseo |
| RE32333 |
A-21978 Antibiotics and process for their production |
January 20, 1987 |
| Antibiotic A-21978 complexes, in particular the A-21978C complex, comprising microbiologically active, related factors C.sub.0, C.sub.1, C.sub.2, C.sub.3, C.sub.4, and C.sub.5. A-21978 complex and A-21978C complex are produced by submerged aerobic fermentation of Streptomyces roseosp |
| RE32311 |
Derivatives of A-21978C cyclic peptides |
December 16, 1986 |
| A-21978C cyclic peptide derivatives of the formula ##STR1## wherein R is hydrogen, a specified aminoacyl or N-alkanoylaminoacyl group, 8-methyldecanoyl, 10-methyldodecanoyl, 10-methylundecanoyl, the specific C.sub.10 -alkanoyl group of A-21978C.sub.0 or the specific C.sub.12 -alk |
| RE32310 |
Derivatives of A-21978C cyclic peptides |
December 16, 1986 |
| A-21978C cyclic peptide derivatives of the formula ##STR1## wherein R is a substituted benzoyl group of the formula ##STR2## R.sup.2 is C.sub.8 -C.sub.15 alkyl; X is hydrogen, chloro, bromo, iodo, nitro, C.sub.1 -C.sub.3 alkyl, hydroxy, C.sub.1 -C.sub.3 alkoxy, or C.sub.1 -C. |
| RE31396 |
A-21978 Antibiotics and process for their production |
September 27, 1983 |
| Antibiotic A-21978 complexes, in particular the A-21978C complex, comprising microbiologically active, related factors C.sub.0, C.sub.1, C.sub.2, C.sub.3, C.sub.4, and C.sub.5. A-21978 complex and A-21978C complex are produced by submerged aerobic fermentation of Streptomyces roseosp |
| RE31227 |
4-Trifluoromethyl-2,6-dinitroanilines |
May 3, 1983 |
| This invention relates to a group of novel substituent anilines, useful in eliminating germinating and seedling weed grasses and selected broadleaf weeds. |
| RE31226 |
4-Trifluoromethyl-2,6-dinitroanilines |
May 3, 1983 |
| This invention relates to a group of novel substituent anilines, useful in eliminating germinating and seedling weed grasses and selected broadleaf weeds. |
| RE30563 |
Preparation of benzoylureas |
March 31, 1981 |
| Benzoylureas are prepared from a benzamide, an alkyllithium, a phenyl chloroformate, and an amine. Two reaction sequences are described. The benzoylureas obtained by the process are useful as insecticides. |
| RE30561 |
Vinca alkaloid intermediates |
March 31, 1981 |
| 3-Spiro-5"-oxazolidine-2",4"-dione derivatives of Vinca alkaloids, useful as anti-tumor agents and as intermediates. |
| RE30560 |
Oxazolidinedione derivatives of Vinca alkaloids |
March 31, 1981 |
| 3-Spiro-5"-oxazolidine-2",4"-dione derivatives of Vinca alkaloids, useful as anti-tumor agents and as intermediates. |
| RE30415 |
Substituted pyrroloquinoxalinones and diones |
October 7, 1980 |
| Substituted pyrroloquinoxalinones and diones, useful as anti-inflammatory and anti-thrombotic agents. |
| RE30314 |
Substituted pyrroloquinoxalinones and diones |
June 24, 1980 |
| Substituted pyrroloquinoxalinones and diones, useful as anti-inflammatory and anti-thrombotic agents. |
| RE30219 |
Method of preparing 8,8-disubstituted-6-methylergolines and related compounds |
February 19, 1980 |
| 8,8-Disubstituted-6-methylergolines and 9-ergolenes, are prepared by alkylation of lysergic, or isolysergic acid or their 9,10-dihydro analogues. |
| RE30218 |
8,8-Disubstituted-6-methylergolines and related compounds |
February 19, 1980 |
| 8,8-Disubstituted-6-methylergolines and 9-ergolenes, prepared by alkylation of lysergic, isolysergic or their 9,10-dihydro analogues, optionally followed by chemical modification of an 8-substituent. |
| RE29508 |
Ring-substituted N-(2,2-difluoroalkanoyl)-o-phenylenediamine compounds |
January 3, 1978 |
| Ring-substituted N-(2,2-difluoroalkanoyl)-o-phenylenediamine compounds useful as herbicides and as insecticides; and combinations of these compounds with known herbicides. |
| RE29465 |
Psoriasis treatment with mycophenolic acid |
November 1, 1977 |
| Psoriasis is treated orally .[.and topically.]. with mycophenolic acid or its .beta.-D-glucuronide. |
| RE29367 |
Fluoroalkoxyphenyl-substituted nitrogen heterocycles as plant stunting agents |
August 23, 1977 |
| There is disclosed a class of fluoroalkoxyphenylsubstituted nitrogen-containing heterocycles which are useful as herbicides, plant fungicides, and plant growth regulators. Internodal elongation of plants is inhibited by treatment with compounds of this invention. |
| RE28865 |
Selective dehalogenation |
June 15, 1976 |
| An improved process for removal of halogen from the pyrimidine ring only of a compound of the formula ##SPC1##WhereinAt least one of X is chlorine or bromine, the remainder hydrogen; .[.or lower alkyl.].Q is chlorine or fluorine; andN is an integer from 1 to 5.The dehalogenation process |
| H2085 |
Penicillin binding protein from Streptococcus pneumoniae |
October 7, 2003 |
| The invention provides isolated nucleic acid compounds encoding a novel high molecular weight PBP of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the PBP and a method for identifying compounds that bind and/or inhibit the enzy |
| H2071 |
Streptococcus pneumoniae gene HI0454 |
July 1, 2003 |
| The invention provides isolated nucleic acid compounds encoding the 454 gene of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein. |
| H2070 |
Streptococcus pneumoniae gene sequence for DNA ligase |
July 1, 2003 |
| The invention provides isolated nucleic acid compounds encoding a DNA ligase of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein. |
| H2023 |
Streptococcus pneumoniae sequence GrpE |
May 7, 2002 |
| The invention provides isolated nucleic acid compounds encoding GrpE of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein. |
| H2022 |
Inositolphosphoryl ceramide (IPC) synthase genes from fungi |
May 7, 2002 |
| The invention provides isolated nucleic acid compounds encoding IPC synthase or subunit thereof from fungal cells. Also provided are vectors and transformed heterologous host cells for expressing IPC synthase and a method for identifying compounds that inhibit a fungal IPC synthase. |
| H2021 |
Penicillin binding protein from Streptococcus pneumoniae |
May 7, 2002 |
| The invention provides isolated nucleic acid compounds encoding a novel high molecular weight PBP of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the PBP and a method for identifying compounds that bind and/or inhibit the enzy |
| D464734 |
Well plate seal |
October 22, 2002 |
|
| D462760 |
Medication delivery apparatus |
September 10, 2002 |
|
| D456896 |
Medication reconstituting apparatus |
May 7, 2002 |
|
| D426299 |
Medication delivery instrument |
June 6, 2000 |
|
| D414271 |
Reaction vessel for combining chemicals |
September 21, 1999 |
|
| D399313 |
Syringe alignment device |
October 6, 1998 |
|
| D390702 |
Barrel top tray |
February 17, 1998 |
|
| D380827 |
Multi-cartridge medication injector |
July 8, 1997 |
|
| D351466 |
Medication injector |
October 11, 1994 |
|
| D351465 |
Medication injector |
October 11, 1994 |
|
| D290229 |
Fragrance container |
June 9, 1987 |
|
| D284548 |
Fragrance container |
July 8, 1986 |
|
| D284411 |
Capsule |
June 24, 1986 |
|
| D275838 |
Bottle cap |
October 9, 1984 |
|
| D271623 |
Animal capsule |
November 29, 1983 |
|
