| Patent Number |
Title Of Patent |
Date Issued |
| RE34387 |
Method for restoring depleted purine nucleotide pools |
September 21, 1993 |
| A method of increasing the rate of repletion of purine nucleotide pools in tissue deficient in the nucleotides, which comprises administering to a human or animal a therapeutically effective amount of 5-amino-4-imidazolecarboxamide riboside, 5-amino-4-imidazolecarboxamide, or a pharm |
| 7449449 |
Particle-mediated transformation of vertebrate tissue cells |
November 11, 2008 |
| A method of transferring a gene to vertebrate cells is disclosed. The method comprises the steps of: (a) providing microprojectiles, the microprojectiles carrying polynucleic acid sequences, the sequences comprising, in the 5' to 3' direction, a regulatory sequence operable in the ti |
| 7439019 |
Methods of identifying individuals at risk of perioperative bleeding, renal dysfunction |
October 21, 2008 |
| The present invention relates, in general, to perioperative bleeding and, in particular, to methods of identifying individuals at risk of perioperative bleeding.The present invention relates, in general, to perioperative renal dysfunction and, in particular, to methods of identifying |
| 7439014 |
Droplet-based surface modification and washing |
October 21, 2008 |
| The present invention relates to droplet-based surface modification and washing. According to one embodiment, a method of providing a droplet in contact with a surface with a reduced concentration of a substance is provided, wherein the method includes: (a) providing a droplet microa |
| 7432843 |
Compressive sampling and signal inference |
October 7, 2008 |
| A signal is temporally compressively sampled. A plurality of analog to digital converters are assembled to sample the signal. Each analog to digital converter of the plurality of analog to digital converters is configured to sample the signal at a time step determined by a temporal s |
| 7432052 |
Method and identification of downstream mRNA ligands to FMRP and their role in fragile X syndrom |
October 7, 2008 |
| Compositions and methods for identifying and/or modulating RNA transcripts and/or genes involved in fragile X syndrome and other associated disorders are provided. In particular, RNA targets for fragile X mental retardation protein (FMRP) have been identified by a novel monoclonal an |
| 7429580 |
Compositions of an anticonvulsant and an antipsychotic drug and methods of using the same for af |
September 30, 2008 |
| Disclosed are compositions for affecting weight loss comprising a first compound and a second compound, where the first compound is a psychotherapeutic agent and the second compound is a anticonvulsant. Also disclosed are methods of affecting weight loss, increasing energy expenditur |
| 7429458 |
Methods of using bioelastomers |
September 30, 2008 |
| Bioelastomers are disclosed for use in methods of binding compounds including immunoassay methods, in biosensors and methods or regenerating biosensors, and in methods for targeting the delivery of a compound to a particular location within an animal subjects. In general, the bioelas |
| 7427932 |
Compressive sampling and signal inference |
September 23, 2008 |
| An optical signal is copressively sampled using an imaging system. The imaging system is created from a plurality of subimaging systems. Each subimaging system comprises a subaperture and a plurality of sensors. The optical signal is collected at each subaperture of the plurality of |
| 7425445 |
Modulators that promote cell surface expression of odorant receptors |
September 16, 2008 |
| The present invention relates to polypeptides capable of promoting odorant receptor cell surface localization and odorant receptor functional expression. The present invention further provides assays for the detection of ligands specific for various odorant receptors. Additionally, t |
| 7420724 |
Scanner apparatus having electromagnetic radiation devices coupled to MEMS actuators |
September 2, 2008 |
| A disclosed scanner apparatus includes a member having spaced apart proximal and distal portions. An electromagnetic radiation device is configured to direct electromagnetic radiation therefrom and is moveably coupled to the distal portion of the member. The electromagnetic radiation |
| 7417109 |
Polymers for delivering nitric oxide in vivo |
August 26, 2008 |
| Disclosed are novel polymers derivatized with at least one --NO.sub.x group per 1200 atomic mass unit of the polymer. X is one or two. In one embodiment, the polymer is an S-nitrosylated polymer and is prepared by reacting a polythiolated polymer with a nitrosylating agent under cond |
| 7415143 |
Methods and systems for the detection of malignant melanoma |
August 19, 2008 |
| The present invention relates to the detection of malignant melanoma. In particular, the present invention relates to systems and methods for the early detection of cancerous lesions. |
| 7413906 |
Quantitative, high-throughput screening method for protein stability |
August 19, 2008 |
| In proteomic research, it is often necessary to screen a large number of polypeptides for the presence of stable structure. Described herein are methods (referred to as MALDI MS-HX and SUPREX) for measuring the stability of proteins in a rapid, high-throughput fashion. The method emp |
| 7407987 |
Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins |
August 5, 2008 |
| A method for treating hair loss in mammals uses compositions containing prostaglandin F analogs. The compositions can be applied topically to the skin. The compositions can arrest hair loss, reverse hair loss, and promote hair growth. |
| 7399957 |
Coded mass spectroscopy methods, devices, systems and computer program products |
July 15, 2008 |
| A coded mass spectrometer incorporates a spatial or temporal code to reduce the resolution/sensitivity dichotomy inherent in mass spectrometry. The code is used to code one or more portions of a mass spectrometer. Coding patterns, such as Hadamard codes, Walsh codes, and perfect code |
| 7388029 |
Compositions and methods for treating hair loss using non-naturally occurring prostaglandins |
June 17, 2008 |
| A method for treating hair loss in mammals uses compositions containing prostaglandin F analogs. The compositions can be applied topically to the skin. The compositions can arrest hair loss, reverse hair loss, and promote hair growth. |
| 7384907 |
Method of treating infection with ABl tyrosine kinase inhibitors |
June 10, 2008 |
| The present invention relates to a method of preventing or treating a pathogen infection comprising administering to a mammal in need thereof an effective amount of an inhibitor of Abl tyrosine kinase. |
| 7374538 |
Methods, systems, and computer program products for ultrasound measurements using receive mode p |
May 20, 2008 |
| A pushing pulse is delivered from an ultrasound transducer array having a plurality of elements to a target region within a medium to displace the target region to a displaced position. A tracking pulse is delivered from the ultrasound transducer array to the target region, and a plurali |
| 7371522 |
Use of polymorphism of the serotonin transporter gene promoter as a predictor of disease risk |
May 13, 2008 |
| The present invention provides a method of screening subjects for disease risk. The method comprises determining the serotonin transporter gene promoter genotype of a subject. The serotonin transporter gene promoter genotype is used to indicate whether or not the subject is at increased |
| 7364859 |
Methods of using bioelastomers |
April 29, 2008 |
| Bioelastomers are disclosed for use in methods of binding compounds including immunoassay methods, in biosensors and methods or regenerating biosensors, and in methods for targeting the delivery of a compound to a particular location within an animal subjects. In general, the bioelas |
| 7358234 |
Induction of a protective immune response through microprojectiles coated with a DNA sequence en |
April 15, 2008 |
| The present invention relates to a process for inducing a protective immune response in a mammal against a virus, in which a construct including a promoter and a DNA sequence encoding a protein or peptide producing an immune response against the virus is introduced into muscle or ski |
| 7358043 |
Proteomic interaction and genomic action determinations in the presence of associated redox stat |
April 15, 2008 |
| Genomic actions and/or proteomic interactions for pathophysiological processes and for physiological processes are determined at associated redox state conditions. Protein interactions are correlated with oxygen tensions. Identification of markers for disease including epitopes is ef |
| 7355023 |
Isolated nucleic acids and polypeptides associated with glucose homeostasis disorders and method |
April 8, 2008 |
| An isolated and substantially pure nucleic acid sequence located between D20S119 and D20S178 on human chromosome 20q13, the nucleic acid sequence including: a nucleic acid sequence coding for a glucose transporting protein and having the sequence shown in SEQ ID NO: 1; or a nucleic acid |
| 7351975 |
Sensor system for identifying and tracking movements of multiple sources |
April 1, 2008 |
| A system identifies a human being from the movement of the human being. The system includes a dual element pyroeleetric detector, a Fresnel lens array, and a processor. The dual element pyroelectric detector detects radiation from the human being as the human being moves over time. The |
| 7338670 |
Use of an agent that restores tissue perfusion and oxygenation |
March 4, 2008 |
| The presently disclosed subject matter provides methods for increasing perfusion in hypoxic regions of tissues in subjects. Also provided are methods for treating diseases and/or disorders associated with hypoxia in subjects, methods for increasing sensitivity of tumors to radiation |
| 7336366 |
Methods and systems for reducing complex conjugate ambiguity in interferometric data |
February 26, 2008 |
| A complex conjugate ambiguity can be resolved in an Optical Coherence Tomography (OCT) interferogram. A reference light signal is propagated along a reference path. A sample light signal is impinged on a sample reflector. The reference light signal is frequency shifted with respect t |
| 7336353 |
Coding and modulation for hyperspectral imaging |
February 26, 2008 |
| Embodiments of the present invention relate to systems and methods for spectral imaging. In one embodiment, an image of the scene is formed on a coded aperture of a spectrometer. A coded image from the coded aperture is detected on a two-dimensional detector array of the spectrometer |
| 7329545 |
Methods for sampling a liquid flow |
February 12, 2008 |
| In a method for sampling a continuous liquid flow, the liquid flow is supplied to a surface along an input flow path. The liquid flow is sampled by forming a sample droplet from a portion of the liquid flow. The sample droplet is moved along an analysis flow path to a processing area |
| 7329543 |
Red blood cells loaded with S-nitrosothiol and uses therefor |
February 12, 2008 |
| Red blood cells can be loaded with low molecular weight nitrosylating agents, such as S-nitrosothiols, to act as a delivery system for NO.sup.+ groups to tissues. Loaded red blood cells can be used in methods of therapy for conditions which are characterized by abnormal O.sub.2 metab |
| 7329225 |
Methods, devices, systems and computer program products for oscillating shafts using real time 3 |
February 12, 2008 |
| An oscillating shaft is scanned to provide images including the oscillating shaft in vivo in real-time with a real-time three-dimensional (3D) ultrasound scanner. An interventional device can be guided in vivo using an ultrasound scanner and includes a sheath having a bore therethrou |
| 7319011 |
Method for distinguishing follicular thyroid adenoma (FTA) from follicular thyroid carcinoma (FT |
January 15, 2008 |
| Follicular thyroid adenoma (FTA) is distinguished from follicular thyroid carcinoma (FTC) by comparing amount of an expression product of at least one gene selected from the group consisting of DDIT3, ARG2, ITM1, C1orf24, TARSH, and ACO1 in a test follicular thyroid specimen to a nor |
| 7312325 |
RNA aptamers and methods for identifying the same |
December 25, 2007 |
| RNA aptamers and methods for identifying the same are disclosed. The RNA aptamers selectively bind coagulation factors, E2F family members, Ang1 or Ang2, and therapeutic and other uses for the RNA aptamers are also disclosed. |
| 7307171 |
Materials and methods for inhibiting fouling of surfaces exposed to aquatic environments |
December 11, 2007 |
| The subject invention provides materials and methods for inhibiting the biofouling of surfaces exposed to aquatic environments. In one embodiment, the subject invention provides additives for marine paints and surface treatments. The subject invention further provides repellents and |
| 7307102 |
Method of preventing or treating estrogen-dependent diseases and disorders |
December 11, 2007 |
| The present invention relates, in general, to the treatment of estrogen-dependent diseases and disorders and, in particular, to a method of treating estrogen-dependent cancers, particularly breast cancer, with antiestrogens. |
| 7301625 |
Static two-dimensional aperture coding for multimodal multiplex spectroscopy |
November 27, 2007 |
| A class of aperture coded spectrometer is optimized for the spectral characterization of diffuse sources. The instrument achieves high throughput and high spatial resolution by replacing the slit of conventional dispersive spectrometers with a spatial filter or mask. A number of mask |
| 7300922 |
Modulators of pharmacological agents |
November 27, 2007 |
| The biological activity of nucleic acid ligand is regulated (i.e. enhanced or inhibited) in vivo to produce a desired biological effect. This is accomplished through the administration of a modulator, or regulator, that changes the binding of the nucleic acid ligand for its target or |
| 7299089 |
Methods, systems, and computer program products for neural channel selection in a multi-channel |
November 20, 2007 |
| Methods, systems, and computer program products for transmitting neural signal information. Methods, systems, and computer programs products are disclosed for neural channel selection in a multi-channel system. A method according to one embodiment can include a step for receiving a p |
| 7286389 |
Low-power, p-channel enhancement-type metal-oxide semiconductor field-effect transistor (PMOSFET |
October 23, 2007 |
| Low-power, all-p-channel enhancement-type metal-oxide semiconductor field-effect transistor (PMOSFET) SRAM cells are disclosed. A PMOSFET SRAM cell is disclosed. The SRAM cell can include a latch having first and second PMOSFETs for storing data. Further, a gate of the first PMOSFET |
| 7283232 |
Optical spectroscopy with overlapping images |
October 16, 2007 |
| An optical spectrometer distinguishes ambiguity between different wavelength constituent components present in incident light. A spatial filter in the spectrometer spatially filters the incident light. A dispersion system receives the spatially filtered light and disperses images of |
| 7283231 |
Compressive sampling and signal inference |
October 16, 2007 |
| A transmission mask or cooled aperture is used in spectroscopy to compressively sample an optical signal. The locations of transmissive and opaque elements of the mask are determined by a transmission function. The optical signal transmitted by the mask is detected at each sensor of |
| 7282521 |
Anti-retroviral moronic acid derivatives |
October 16, 2007 |
| The present invention provides moronic acid derivatives of the general formula: ##STR00001## which have antiviral activity, along with compositions containing the same and methods of use thereof. |
| 7279324 |
Nucleic acid encoding G-protein coupled receptor with modified DRY motif |
October 9, 2007 |
| The present invention relates to modified G-protein coupled receptors (GPCRs). The modified GPCRs of the present invention include GPCRs that have been modified to have altered DRY motifs such that the modified GPCRs are constitutively desensitized. As such, the modified GPCRs of the |
| 7276588 |
Antibody of human mitochondrial voltage dependent anion channel |
October 2, 2007 |
| An isolated antibody that binds to a plasminogen kringle 5 receptor, i.e., the human voltage-dependent anion channel, preferably at an epitope between amino acids Tyr.sub.224 through Lys.sub.255 thereof, is described, along with methods of use thereof. Peptides or immunogens that sti |
| 7273614 |
Nucleic acids encoding DP-178 and other viral fusion inhibitor peptides useful for treating aids |
September 25, 2007 |
| The present invention relates to peptides which exhibit potent anti-retroviral activity. The peptides of the invention comprise DP178 (SEQ ID:1) peptide corresponding to amino acids 638 to 673 of the HIV-1.sub.LAI gp41 protein, and fragments, analogs and homologs of DP178. The invent |
| 7259250 |
C-nitroso compounds and use thereof |
August 21, 2007 |
| A C-nitroso compound having a molecular weight ranging from 225 to 1,000 (from 225 to 600 for oral administration) on a monomeric basis wherein a nitroso group is attached to a tertiary carbon, which is obtained by nitrosylation of a carbon acid having a pKa less than about 25, is useful |
| 7250100 |
Two dimensional electrophoresis cassette |
July 31, 2007 |
| A device for two-dimensional electrophoresis includes a cassette comprising two opposing plates. The two opposing plates form a first elongated portion for receiving a first elongated electrophoretic separation medium and a second portion extending away from the first portion. A seco |
| 7241795 |
Synthesis and antimicrobial activity of novel dicationic "reversed amidines" |
July 10, 2007 |
| The present invention relates to novel 2,5-bis{[alkyl (or aryl) imino]aminophenyl}furans and thiophenes of the general formula ##STR00001## in which R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are each independently selected from the group consisting of H, alkyl, alkoxy, halide, and alkyl |
| 7238793 |
Estrogen receptor modulators |
July 3, 2007 |
| The present invention relates to an estrogen receptor co-regulator and to antibodies specific therefor. The invention further relates to methods of screening test compounds for their suitability as estrogen receptor modulators and to methods of using same in disease treatment. |
| 7235649 |
Isolated GRP94 ligand binding domain polypeptide and nucleic acid encoding same, and screening m |
June 26, 2007 |
| We claim an isolated nucleic acid molecule encoding a ligand binding domain of glucose regulated protein of 94 kDa (GRP94), a chimeric polynucleotide consisting of said nucleic acid molecule operably linked to a heterologous promoter wherein said nucleic acid molecule is optionally l |
