| Patent Number |
Title Of Patent |
Date Issued |
| RE38775 |
Electrode with improved signal to noise ratio |
August 16, 2005 |
| An electrode assembly for sensing an electrochemical signal diffused from a source to a working electrode which is comprised of a plurality of substantially separated working electrode surfaces is disclosed. The electrode of the invention is comprised of 1) a working electrode made up |
| RE38681 |
Electrode with improved signal to noise ratio |
January 4, 2005 |
| An electrode assembly for sensing an electrochemical signal diffused from a source to a working electrode which is comprised of a plurality of substantially separated working electrode surfaces is disclosed. The electrode of the invention is comprised of 1) a working electrode made up |
| D438807 |
Cover for quality control testing of an iontophoretic sampling system |
March 13, 2001 |
|
| 6941163 |
Formulation and manipulation of databases of analyte and associated values |
September 6, 2005 |
| The present invention relates to methods of formulating analyte data databases, the databases themselves, and methods of manipulating the same. In one aspect the present invention includes the formulation of analyte data points, derived data, and data attributes databases comprising data |
| 6902905 |
Glucose measuring assembly with a hydrogel |
June 7, 2005 |
| This invention relates to methods for reducing the presence of a compound in an ionically conductive material, e.g., for use in iontophoretic devices, wherein the presence of the compound interferes with detecting a selected analyte. Removal of the compound can typically take place eithe |
| 6885883 |
Methods for improving performance and reliability of biosensors |
April 26, 2005 |
| The present invention relates to a predictive-kinetic method for use with data processing of a sensor-generated signal, as well as, microprocessors and monitoring systems employing such a predictive-kinetic method. Data from a transient region of a signal is used with suitable models and |
| 6882940 |
Methods and devices for prediction of hypoglycemic events |
April 19, 2005 |
| Described herein are methods, devices, and microprocessors useful for predicting a hypoglycemic event in a subject. The hypoglycemic predictive approach described herein utilizes information obtained from a data stream, e.g., frequently obtained glucose values (current and/or predict |
| 6862466 |
Methods of monitoring glucose levels in a subject and uses thereof |
March 1, 2005 |
| Methods of frequently monitoring glucose amounts and/or concentrations in a subject who is at risk for hypoglycemia, hyperglycemia, and/or glucose level fluctuations that put the subject at risk are provided. Also provided are methods of monitoring the effects of one or more pharmace |
| 6850790 |
Monitoring of physiological analytes |
February 1, 2005 |
| Methods and devices are provided for measuring the concentration of target chemical analytes present in a biological system. Device configuration and/or measurement techniques are employed in order to reduce the effect of interfering species on sensor sensitivity. One important applicati |
| 6816742 |
Biosensor and methods of use thereof |
November 9, 2004 |
| An automated system for continual transdermal extraction of analytes present in a biological system is provided. The system can be used for detecting and/or measuring the concentration of the analyte using an electrochemical biosensor detection means. The system optionally uses rever |
| 6771995 |
Chemical signal-impermeable mask |
August 3, 2004 |
| A chemical signal-impermeable mask is positioned in the electrolyte flow such that the mask is between a source of chemical signal and a working electrode which senses the chemical signal transported from the source (e.g., by diffusion). The configuration of the mask is such that the mas |
| 6736777 |
Biosensor, iontophoretic sampling system, and methods of use thereof |
May 18, 2004 |
| The present invention relates generally to a sensor for use in monitoring the amount or concentration of target chemical analytes present in a biological system. For example, the invention relates to a sensor for measuring the amount or concentration of one or more analytes in a tran |
| 6687522 |
Device for sample of substances using alternating polarity |
February 3, 2004 |
| A method for sampling of a substance from a subject is provided, which comprises placing one or more sampling chambers on a collection site on a tissue surface on the subject; conducting electric current through the tissue to extract a substance from the subject in a first direction in o |
| 6633772 |
Formulation and manipulation of databases of analyte and associated values |
October 14, 2003 |
| The present invention relates to methods of formulating analyte data databases, the databases themselves, and methods of manipulating the same. In one aspect the present invention includes the formulation of analyte data points, derived data, and data attributes databases comprising data |
| 6615078 |
Methods and devices for removing interfering species |
September 2, 2003 |
| This invention relates to methods for reducing the presence of a compound in an ionically conductive material, e.g., for use in iontophoretic devices, wherein the presence of the compound interferes with detecting a selected analyte. Removal of the compound can typically take place eithe |
| 6595919 |
Device for signal processing for measurement of physiological analytes |
July 22, 2003 |
| A method is provided for continually or continuously measuring the concentration of target chemical analytes present in a biological system, and processing analyte-specific signals to obtain a measurement value that is closely correlated with the concentration of the target chemical |
| 6594514 |
Device for monitoring of physiological analytes |
July 15, 2003 |
| Methods and devices are provided for measuring the concentration of target chemical analytes present in a biological system. Device configuration and/or measurement techniques are employed in order to reduce the effect of interfering species on sensor sensitivity. One important applicati |
| 6561978 |
Devices and methods for frequent measurement of an analyte present in a biological system |
May 13, 2003 |
| Devices and methods are provided for frequently measuring the concentration of an analyte present in a biological system. A monitoring system having at least two components is employed in order to allow separation of data collection from data processing and display. Such separation allow |
| 6553244 |
Analyte monitoring device alarm augmentation system |
April 22, 2003 |
| The present invention relates to a device for augmenting an alarm signal generated by an analyte monitoring device, e.g., the GlucoWatch.RTM. (Cygnus, Inc., Redwood City, Calif.) biographer glucose monitoring device, for improving the alarm signal's effectiveness in alerting the user, |
| 6546269 |
Method and device for predicting physiological values |
April 8, 2003 |
| A method and device are provided for measuring the concentration of target chemical analytes present in a biological system, and then predicting a future or past concentration of an analyte using a series of such measurements. One important application of the invention involves predi |
| 6529755 |
Chemical signal-impermeable mask |
March 4, 2003 |
| A chemical signal-impermeable mask is positioned in the electrolyte flow such that the mask is between a source of chemical signal and a working electrode which senses the chemical signal transported from the source (e.g., by diffusion). The configuration of the mask is such that the mas |
| 6438414 |
Collection assemblies, laminates, and autosensor assemblies for use in transdermal sampling syst |
August 20, 2002 |
| The invention relates generally to consumable components of a device used for continually or continuously measuring the concentration of target chemical analytes present in a biological system. More particularly, the invention relates to collection assemblies, laminate structures, and |
| 6398562 |
Device and methods for the application of mechanical force to a gel/sensor assembly |
June 4, 2002 |
| Devices and methods are described for improving the contact of a conductive material, for example, a hydrogel, with a sensor, for example an electrode, by means of using mechanical force to apply the conductive material to the sensor before use of the conductive material and sensor in |
| 6393318 |
Collection assemblies, laminates, and autosensor assemblies for use in transdermal sampling syst |
May 21, 2002 |
| The invention relates generally to consumable components of a device used for continually or continuously measuring the concentration of target chemical analytes present in a biological system. More particularly, the invention relates to collection assemblies, laminate structures, and |
| 6391643 |
Kit and method for quality control testing of an iontophoretic sampling system |
May 21, 2002 |
| An automated system for continual transdermal extraction of analytes present in a biological system is described. The system optionally uses reverse iontophoresis to carry out the continual transdermal extraction of the analytes. The present invention describes quality control test kits, |
| 6370410 |
Methods of producing an assembly for use in a monitoring device |
April 9, 2002 |
| A chemical signal-impermeable mask is positioned in the electrolyte flow such that the mask is between a source of chemical signal and a working electrode which senses the chemical signal transported from the source (e.g., by diffusion). The configuration of the mask is such that the mas |
| 6356776 |
Device for monitoring of physiological analytes |
March 12, 2002 |
| Methods and devices are provided for measuring the concentration of target chemical analytes present in a biological system. Device configuration and/or measurement techniques are employed in order to reduce the effect of interfering species on sensor sensitivity. One important applicati |
| 6341232 |
Methods of producing collection assemblies, laminates, and autosensor assemblies for use in tran |
January 22, 2002 |
| The invention relates generally to methods of producing consumable components of a device used for measuring the concentration of target chemical analytes present in a biological system. More particularly, the invention relates methods of producing collection assemblies, laminate str |
| 6326160 |
Microprocessors for use in a device for predicting physiological values |
December 4, 2001 |
| The invention relates generally to methods, systems, and devices for measuring the concentration of target analytes present in a biological system using a series of measurements obtained from a monitoring system and a Mixtures of Experts (MOE) algorithm. In one embodiment, the present |
| 6309351 |
Methods for monitoring a physiological analyte |
October 30, 2001 |
| A method for continual monitoring of a physiologic analyte in a subject includes steps of contacting the subject with a collection reservoir such that the analyte can move from the subject into the collection reservoir, the contents of the collection reservoir being in operative communic |
| 6299578 |
Methods for monitoring a physiological analyte |
October 9, 2001 |
| A method for continual monitoring of a physiologic analyte in a subject includes steps of contacting the subject with a collection reservoir such that the analyte can move from the subject into the collection reservoir, the contents of the collection reservoir being in operative communic |
| 6298254 |
Device for sampling substances using alternating polarity of iontophoretic current |
October 2, 2001 |
| A method for sampling of a substance from a subject is provided, which comprises placing one or more sampling chambers on a collection site on a tissue surface on the subject; conducting electric current through the tissue to extract a substance from the subject in a first direction in o |
| 6284126 |
Electrode with improved signal to noise ratio |
September 4, 2001 |
| An electrode assembly for sensing an electrochemical signal diffused from a source to a working electrode which is comprised of a plurality of substantially separated working electrode surfaces is disclosed. The electrode of the invention is comprised of 1) a working electrode made up |
| 6272364 |
Method and device for predicting physiological values |
August 7, 2001 |
| A method and device are provided for measuring the concentration of target chemical analytes present in a biological system, and then predicting a future or past concentration of an analyte using a series of such measurements. One important application of the invention involves predi |
| 6233471 |
Signal processing for measurement of physiological analysis |
May 15, 2001 |
| A method is provided for continually or continuously measuring the concentration of target chemical analytes present in a biological system, and processing analyte-specific signals to obtain a measurement value that is closely correlated with the concentration of the target chemical |
| 6201979 |
Chemical signal-impermeable mask |
March 13, 2001 |
| A chemical signal-impermeable mask is positioned in the electrolyte flow such that the mask is between a source of chemical signal and a working electrode which senses the chemical signal transported from the source (e.g., by diffusion). The configuration of the mask is such that the mas |
| 6180416 |
Method and device for predicting physiological values |
January 30, 2001 |
| The invention relates generally to methods, systems, and devices for measuring the concentration of target analytes present in a biological system using a series of measurements obtained from a monitoring system and a Mixtures of Experts (MOE) algorithm. In one embodiment, the present |
| 6144869 |
Monitoring of physiological analytes |
November 7, 2000 |
| Methods and devices are provided for measuring the concentration of target chemical analytes present in a biological system. Device configuration and/or measurement techniques are employed in order to reduce the effect of interfering species on sensor sensitivity. One important applicati |
| 6141573 |
Chemical signal-impermeable mask |
October 31, 2000 |
| A chemical signal-impermeable mask is positioned in the electrolyte flow such that the mask is between a source of chemical signal and a working electrode which senses the chemical signal transported from the source (e.g., by diffusion). The configuration of the mask is such that the mas |
| 6139718 |
Electrode with improved signal to noise ratio |
October 31, 2000 |
| An electrode assembly for sensing an electrochemical signal diffused from a source to a working electrode which is comprised of a plurality of substantially separated working electrode surfaces is disclosed. The electrode of the invention is comprised of 1) a working electrode made up |
| 6023629 |
Method of sampling substances using alternating polarity of iontophoretic current |
February 8, 2000 |
| A method for sampling of a substance from a subject is provided, which comprises placing one or more sampling chambers on a collection site on a tissue surface on the subject; conducting electric current through the tissue to extract a substance from the subject in a first direction in o |
| 5989586 |
Two-phase matrix for sustained release drug delivery device |
November 23, 1999 |
| A two-phase hydrophilic drug-containing matrix for use in transdermal drug delivery patches in which one phase is a continuous hydrophobic polymer phase which optionally includes a hydrophobic solvent that acts as a skin permeation enhancer and the other phase is a dispersed particulate |
| 5989409 |
Method for glucose sensing |
November 23, 1999 |
| A method for measuring the concentration of glucose diffused from a source to a working electrode which assembly includes a scavenging electrode is disclosed. The electrode of the invention is comprised of 1) a working electrode; 2) a scavenging electrode; 3) an electroosmotic electrode; |
| 5980932 |
Solid matrix system for transdermal drug delivery |
November 9, 1999 |
| A matrix for containing drugs for transdermal delivery systems is disclosed. The matrix formed of a skin-adhesive acrylate copolymer, attains high rates of drug delivery without the addition of drug delivery rate enhancers. In preferred embodiments the matrix is used to administer st |
| 5972377 |
Transdermal patch and method for administering 17-deacetyl norgestimate alone or in combination |
October 26, 1999 |
| Compositions and methods for preventing ovulation in a woman are provided, as well as compositions and methods for female hormone replacement therapy. The compositions can be administered by the use of a transdermal patch. The patch will administer 17-deacetyl norgestimate alone or in |
| 5962013 |
Monolithic matrix transdermal delivery system for administering molsidomine |
October 5, 1999 |
| This invention provides monolithic matrix formulations for transdermal administration of molsidomine. The device includes a copolymer of 2-ethylhexyl acrylate, 2-hydroxyethylmethacrylate, and methacrylic acid. The invention also provides transdermal devices having a monolithic matrix |
| 5954685 |
Electrochemical sensor with dual purpose electrode |
September 21, 1999 |
| The present invention provides an electrode assembly for use in a transdermal analyte sensor operating in an alternating polarity mode in which a single electrode element provides both the counter electrode and iontophoretic electrode functions. By combining both the functions of the |
| 5928666 |
Crystalline form of estradiol and pharmaceutical formulations comprising same |
July 27, 1999 |
| The present invention is directed to a stable crystalline form of estradiol suitable for incorporation into pharmaceutical formulations. The invention further provides methods of preparing said crystalline form of estradiol. The invention further provides pharmaceutical formulations comp |
| 5906830 |
Supersaturated transdermal drug delivery systems, and methods for manufacturing the same |
May 25, 1999 |
| Methods are provided for manufacturing transdermal drug delivery systems containing supersaturated drug reservoirs, such that higher drug fluxes are obtained. The methods involve heating the drug reservoir components to a predetermined temperature. Generally, this temperature is higher t |
| 5902603 |
Polyurethane hydrogel drug reservoirs for use in transdermal drug delivery systems, and associat |
May 11, 1999 |
| High capacity drug reservoirs are provided for incorporation into transdermal drug delivery systems. The drug reservoirs are hydrogels formulated from polyurethanes crosslinked with diisocyanate crosslinking agents or cured with radiation in the presence of a photoinitator. Drug load |
