| Patent Number |
Title Of Patent |
Date Issued |
| H1324 |
Extracorporeal circulation system |
June 7, 1994 |
| A system for controlling and monitoring the extracorporeal circulation of fluids, which is particularly useful in controlling and monitoring the circulation of blood and cardioplegia solution in surgical procedures. A set of perfusion assemblies are mounted in a transportable console, ea |
| D406894 |
Apheresis system |
March 16, 1999 |
|
| D406893 |
Apheresis system |
March 16, 1999 |
|
| D314824 |
Blood centrifuge or the like |
February 19, 1991 |
|
| 6153113 |
Method for using ligands in particle separation |
November 28, 2000 |
| A system and method are disclosed for separating particles having different sedimentation velocities. The system includes a container containing a binding substance including first particles and ligands attached to the first particles. When the binding substance is mixed with a liquid |
| 6129656 |
Extracorporeal blood processing methods and apparatus |
October 10, 2000 |
| An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various |
| 6071422 |
Particle separation method and apparatus |
June 6, 2000 |
| An apparatus and method are disclosed for filtering or separating particles. The apparatus has a centrifuge rotor rotatable about an axis of rotation. A fluid chamber rotates with the rotor. A substance is supplied to the inlet of the chamber. A saturated fluidized bed of first particles |
| 6051146 |
Methods for separation of particles |
April 18, 2000 |
| A system and method are disclosed for separating particles having different sedimentation velocities. The system includes a fluid chamber for separating the particles form one another. Conduits are provided for flowing liquid carrying particles to the fluid chamber and for mixing the |
| 6046225 |
Method of treatment with medical agents |
April 4, 2000 |
| A method of therapeutic or diagnostic treatment using a medical agent in which there will be beneficial effects if the level of circulating medical agent is reduced artificially faster than the reduction by the normal clearance or routes that obviate normal clearance mechanisms. The meth |
| 6022306 |
Method and apparatus for collecting hyperconcentrated platelets |
February 8, 2000 |
| The instant invention relates to a method and the apparatus for collecting a hyperconcentrated platelet product. A fluid containing platelets and other particles flows into a fluid chamber at a flow rate. The flow rate of the fluid is selected to retain the majority of the platelets in t |
| 6007978 |
Method of freezing cells and cell-like materials |
December 28, 1999 |
| A process is provided for freezing, including freeze-drying of cells, cell-membranes or cell-like materials using a cryoprotectant medium which stabilizes the cells or membranes for freezing or freeze-drying and allows for freezing or freeze-drying to be performed at -60.degree. C. or hi |
| 6003556 |
Hinged cap fluid connector |
December 21, 1999 |
| A capped connector for a tubing set and/or medical equipment is provided. The connector comprises a hollow tube having a cap securing leash pivotally attached to its exterior. A cap is pivotally attached to the leash's opposing end. The leash is designed to hold the cap in an orienta |
| 5970423 |
Blood component collection system with optimizer |
October 19, 1999 |
| A blood component collection system with optimization capabilities. In one embodiment, process parameters are derived from an input/configured predetermined blood component yield and which is based upon the maximization of at least one process parameter. Thereafter, the blood compone |
| 5958670 |
Method of freezing cells and cell-like materials |
September 28, 1999 |
| A process is provided for freezing, including freeze-drying of cells, cell-membranes or cell-like materials using a cryoprotectant medium which stabilizes the cells or membranes for freezing or freeze-drying and allows for freezing or freeze-drying to be performed at -60.degree. C. or hi |
| 5954626 |
Method of minimizing coriolis effects in a centrifugal separation channel |
September 21, 1999 |
| A centrifuge separation device is disclosed and includes a rotor configured to be connected to a centrifuge motor for rotation about an axis of rotation. A retainer is associated with the rotor and defines a passageway for a separation channel. A protrusion formed in one of the passagewa |
| 5951877 |
Particle filter method |
September 14, 1999 |
| An apparatus and method are disclosed for filtering or separating particles. The apparatus has a motor coupled to a centrifuge rotor rotatable about an axis of rotation. A fluid chamber rotates with the rotor. A substance is supplied to the inlet of the chamber. At least one of the m |
| 5948251 |
Technique for using a dialysis machine to disinfect a blood tubing set |
September 7, 1999 |
| A method of disinfecting a blood tubing set on a dialysis machine after the blood tubing set has been used in a dialysis treatment. One end of the blood tubing set is connected to a disinfection port on the dialysis machine and an opposite end of the blood tubing set is connected to a |
| 5941842 |
Extracorporeal blood processing methods and apparatus |
August 24, 1999 |
| An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various |
| 5939319 |
Particle separation method and apparatus |
August 17, 1999 |
| An apparatus and method are disclosed for filtering or separating particles. The apparatus has a centrifuge rotor rotatable about an axis of rotation. A fluid chamber rotates with the rotor. A substance is supplied to the inlet of the chamber. A saturated fluidized bed of first particles |
| 5936714 |
Red blood cell spillover detection technique |
August 10, 1999 |
| An apparatus and a method are provided to monitor a generally transparent blood tube at a location that is downstream from a blood separator in order to detect the presence of red blood cells in a tube that is intended to carry a different blood component, for example platelets. A red li |
| 5928177 |
Technique for loading a pump header within a peristaltic pump of a dialysis machine |
July 27, 1999 |
| A pivotable cover secures a pump header or tubing to a peristaltic pump of a dialysis machine. The cover includes an integral raceway for engaging the pump header as a rotor of the peristaltic pump rotates along the integral raceway. The cover is pivoted away from the dialysis machine to |
| 5922162 |
Gas-permeable pathogen-resistant labyrinthine seal and method for making labyrinthine seal |
July 13, 1999 |
| A gas-permeable, pathogen-resistant seal for sealing packages containing medical products is described. The seal comprises a labyrinthine passage, preferably formed in two dimensions, through which bacteria cannot pass. The seal functions to block the passage of bacteria without an addit |
| 5921950 |
Extracorporeal blood processing methods and apparatus |
July 13, 1999 |
| An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various |
| 5919154 |
Extracorporeal blood processing methods and apparatus |
July 6, 1999 |
| An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various |
| 5919125 |
Centrifuge bowl for autologous blood salvage |
July 6, 1999 |
| An improved centrifuge bowl and related system is disclosed which is particularly apt for enhanced autologous blood salvage applications. The centrifuge bowl assembly includes a rotatable outer bowl, an internal spacer interconnected therewithin, and a stator assembly for introducing |
| 5913768 |
Particle filter apparatus |
June 22, 1999 |
| An apparatus and method are disclosed for filtering or separating particles. The apparatus has a motor coupled to a centrifuge rotor rotatable about an axis of rotation. A fluid chamber rotates with the rotor. A substance is supplied to the inlet of the chamber. At least one of the m |
| 5910252 |
Technique for extracorporeal treatment of blood |
June 8, 1999 |
| Blood from a patient is treated extracorporeally by any selected one of a plurality of predetermined treatments. Each of the treatments involves the flow of blood from the patient into a primary chamber of a filtration unit, past a semipermeable membrane located in the filtration unit wh |
| 5906570 |
Particle filter apparatus |
May 25, 1999 |
| An apparatus and method are disclosed for filtering or separating particles. The apparatus has a motor coupled to a centrifuge rotor rotatable about an axis of rotation. A fluid chamber rotates with the rotor. A substance is supplied to the inlet of the chamber. At least one of the m |
| 5900726 |
Differential conductivity hemodynamic monitor |
May 4, 1999 |
| A flow rate of a fluid flowing in a tube is quantitatively determined by altering the electrical conductivity of the fluid by injection of a bolus of saline. The electrical conductivity of the altered conductivity is measured over the time it takes the altered conductivity fluid to pass |
| 5900270 |
Technique for testing and coating a microporous membrane |
May 4, 1999 |
| The integrity of a microporous membrane within a mass transfer device such as an oxygenator is tested simultaneously with applying a biocompatible surfactant to at least the blood-contact surface of the membrane. The membrane integrity test contacts both sides of the microporous membrane |
| 5891080 |
Biological fluid cassette and tubing set |
April 6, 1999 |
| An apparatus for managing and controlling fluid flow through a plurality of fluid conduits includes a chassis, a plurality of conduit occluders mounted in the chassis, each occluder for association with at least one of the plurality of fluid conduits and each being selectively actuatable |
| 5879280 |
Intermittent collection of mononuclear cells in a centrifuge apparatus |
March 9, 1999 |
| A centrifuge apparatus is used for collecting white blood cells, primarily mononuclear cells, from whole blood stratified into layers. A thin mononuclear (MNC) layer is formed at the interface of red blood cells and plasma. A barrier is positioned in the separation vessel of the centrifu |
| 5876321 |
Control system for the spillover collection of sparse components such as mononuclear cells in a |
March 2, 1999 |
| A centrifuge apparatus is used for collecting white blood cells (WBC), primarily mononuclear cells, from whole blood stratified into layers. A thin mononuclear (MNC) layer is formed at the interface of red blood cells and plasma. A barrier is positioned in the separation vessel of the |
| 5849473 |
Method of lyophilization of mammalian sperm cells |
December 15, 1998 |
| A method is provided for the lyophilization of mammalian sperm cells which can be stored and reconstituted to provide morphologically intact cells. The method is advantageous in that the sperm cells may be stored at ambient temperatures for extended periods of time and recovered morp |
| 5837150 |
Extracorporeal blood processing methods |
November 17, 1998 |
| A method for processing blood in an apheresis system is disclosed. The present invention includes selecting a packing factor for separated blood component types in the separation stage(s) of a blood processing vessel. A packing factor is a number that reflects the degree with which the b |
| 5817042 |
Method and apparatus for controlling concentrations in vivos and in tubing systems |
October 6, 1998 |
| A method and apparatus for maximizing the total amount of blood processed during an apheresis procedure by optimizing the concentration of anticoagulant in a donor/patient and the associated extracorporeal tubing set is provided. A simplified model of anticoagulant accumulation in a |
| 5800978 |
Method of freezing cells and cell-like materials |
September 1, 1998 |
| A process is provided for freezing, including freeze-drying of cells, cell-membranes or cell-like materials using a cryoprotectant medium which stabilizes the cells or membranes for freezing or freeze-drying and allows for freezing or freeze-drying to be performed at -60.degree. C. or hi |
| 5795317 |
Extracorporeal blood processing methods and apparatus |
August 18, 1998 |
| An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various |
| 5792038 |
Centrifugal separation device for providing a substantially coriolis-free pathway |
August 11, 1998 |
| A centrifuge separation device is disclosed and includes a rotor configured to be connected to a centrifuge motor for rotation about an axis of rotation. A retainer is associated with the rotor and defines a passageway for a separation channel. A protrusion formed in one of the passagewa |
| 5776345 |
Automatic priming technique |
July 7, 1998 |
| Blood from a patient is treated extracorporeally by any selected one of a plurality of predetermined treatments. Each of the treatments involves the flow of blood from the patient into a primary chamber of a filtration unit, past a semipermeable membrane located in the filtration unit wh |
| 5776091 |
Technique for priming and recirculating fluid through a dialysis machine to prepare the machine |
July 7, 1998 |
| A technique for automatically priming and recirculating sterile fluid through an extracorporeal circuit of a dialysis machine having a blood pump, a dialyzer, and a blood tubing set including an arterial line for drawing blood from a patient and a venous line for returning the blood to |
| 5762805 |
Technique for extracorporeal treatment of blood |
June 9, 1998 |
| Blood from a patient is treated extracorporeally by any selected one of a plurality of predetermined treatments. Each of the treatments involves the flow of blood from the patient into a primary chamber of a filtration unit, past a semipermeable membrane located in the filtration unit wh |
| 5759774 |
Method of detecting circulating antibody types using dried or lyophilized cells |
June 2, 1998 |
| A method is provided for qualitatively detecting in vitro the presence or absence of selected circulating antibody types using a diagnostic kit comprising reconstituted, after lyophilization or evaporative drying, red blood cell samples or other cell or cell-like material which have anti |
| 5750025 |
Disposable for an apheresis system with a contoured support |
May 12, 1998 |
| An extracorporeal blood processing system is disclosed which includes a disposable for an apheresis system. The disposable can include a blood processing vessel and a contoured support. The blood processing vessel includes sidewalls to define the vessel and a blood inlet port and a blood |
| 5738902 |
Biocompatible coated article |
April 14, 1998 |
| The biocompatibility of polymeric and metallic articles used in contact with blood can be substantially improved by coating the articles as described. The coating materials are triblock copolymers of the polylactone-polysiloxane-polylactone type. Optimum biocompatibility is provided |
| 5738644 |
Extracorporeal blood processing methods and apparatus |
April 14, 1998 |
| An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various |
| 5734464 |
Red blood cell spillover detection technique |
March 31, 1998 |
| An apparatus and a method are provided to monitor a generally transparent blood tube at a location that is downstream from a blood separator in order to detect the presence of red blood cells in a tube that is intended to carry a different blood component, for example platelets. A red li |
| 5733398 |
Efficient methods of manufacturing hollow fiber exchangers |
March 31, 1998 |
| An exchanger includes an outer casing having an inlet port and an outlet port for a first fluid, and an inlet port and an outlet port for a second fluid, and a bundle of hollow fibers located within the outer casing and being in flow communication with the inlet and outlet port for the s |
| 5722946 |
Extracorporeal blood processing methods and apparatus |
March 3, 1998 |
| An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various |
| 5722926 |
Method for separating particles |
March 3, 1998 |
| A fluid chamber and method are disclosed for filtering or separating particles. The fluid chamber includes a wall extending between an inlet and outlet to form a fluid chamber interior. The interior converges from a position of maximum cross-sectional area toward the inlet. A groove or a |
