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Closure Medical Corporation Patents
Assignee:
Closure Medical Corporation
Address:
Raleigh, NC
No. of patents:
66
Patents:


1 2


Patent Number Title Of Patent Date Issued
D573710 Dispenser July 22, 2008
D570227 Mesh dispenser June 3, 2008
D559385 Adhesive dispenser/applicator device January 8, 2008
D540470 Adhesive dispenser/applicator device April 10, 2007
D500085 Adhesive dispenser/applicator device December 21, 2004
7371345 Sterilization of medical adhesive kits May 13, 2008
Adhesive compositions, particularly medical adhesive compositions, often include several components that may react differently to different sterilization processes, particularly when combined with one another. The present invention is directed to methods of sterilizing different comp
7331463 Medical procedure kit having medical adhesive February 19, 2008
A medical procedure kit includes a saleable package including: an outer wrap defining at least one sealed and sterile interior portion; at least one sterilized surgical tool located within the at least one interior portion and sterilized after insertion into the at least one interior
7318937 Liquid coating compositions January 15, 2008
Liquid coating compositions are provided that comprise siloxane containing polymer, volatile polydimethylsiloxane, and aliphatic hydrocarbon. The liquid coating compositions preferably comprise from 18-55 weight % of volatile polydimethylsiloxane, from 5-55 weight % of aliphatic hydr
7306390 Applicators, dispensers and methods for dispensing and applying adhesive material December 11, 2007
An applicator/dispenser assembly for dispensing and/or applying an adhesive material comprises: a first body portion and a second body portion, at least one of the first and second body portions being movable relative to the other of the first and second body portions; a cavity in at
7255874 Biocompatible polymers and adhesives: compositions, methods of making and uses related thereto August 14, 2007
Biocompatible polymers and adhesives have a cyanoacrylic core and other substituents such as therapeutic agents, targeting moieties, imaging agents, amino acid residues or other organic moieties. Exemplary uses of inventive compositions include use as sealants and adhesives for medical
6960040 Package assembly with applicator and container for adhesive materials November 1, 2005
A package assembly or kit can be used in conjunction with storing and dispensing adhesive materials. The package assembly can include an enclosure in which an applicator and a container may be positioned. The container contains adhesive material. The enclosure may include a base and
6942875 Adhesive treatment for skin yeast infections September 13, 2005
A method of treating or preventing skin yeast infections, such as cutaneous candidiasis, includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with or susceptible to a skin yeast infection, optionally with at least one of an additional anti-fungal
6896838 Halogenated polymeric containers for 1, 1-disubstituted monomer compositions May 24, 2005
A container made without employing a mold release agent, comprised of halogenated polymeric material provides an extended shelf-life for 1,1-disubstituted ethylene adhesive monomer compositions.
6837027 Method of sterilizing a medical procedure kit containing a medical adhesive January 4, 2005
A medical procedure kit incorporates one or more surgical tools necessary to perform at least part of a medical procedure, along with a container having a quantity of a medical adhesive. Medical adhesives are useful as an alternate or an adjunct to surgical sutures and/or staples in woun
6811341 Multiple-component combining November 2, 2004
A device for use in combining components to form a compound and for applying the compound to a substrate includes a first housing having a first-housing receptacle with a proximal end, a plunger including a proximal end and a distal end, the distal end being disposed in the proximal
6802416 Package assembly with applicator and container for adhesive materials October 12, 2004
A package assembly or kit can be used in conjunction with storing and dispensing adhesive materials. The package assembly can include an enclosure in which an applicator and a container may be positioned. The container contains adhesive material. The enclosure may include a base and
6779657 Single-use applicators, dispensers and methods for polymerizable monomer compound August 24, 2004
A single-use applicator assembly for dispensing and applying a polymerizable monomeric adhesive material includes: a base portion having at least one sealed compartment; a polymerizable monomeric adhesive material contained in the compartment; an applicator at least partially dispose
6767552 Adhesive treatment for oral fungal infection July 27, 2004
A method of treating or preventing oral fungal infection includes applying a polymerizable monomer adhesive composition to an area afflicted with or susceptible to oral fungal infection, optionally with at least one of an additional anti-fungal agent, and allowing the polymerizable monom
6748950 Compositions and medical procedure to treat snoring June 15, 2004
A method of treating snoring, includes injecting least one of a monomer composition, a polymer solution and a microparticle solution into a patient's soft palate, optionally with a least one of an additional medicament, bioactive agent, sclerotic agent or stiffening agent. The inject
6746667 Adhesive treatment for tinea pedis June 8, 2004
A method of treating or preventing tinea pedis, commonly known as Athlete's Foot, includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with or susceptible to tinea pedis, optionally with at least one of an additional anti-fungal agent or a foot care
6743858 Sterilized cyanoacrylate solutions containing thickeners June 1, 2004
A method of making a sterile adhesive composition includes placing a mixture of a polymerizable adhesive monomer and a thickening agent in a container, sealing the container, and sterilizing the mixture and the container. The method provides superior viscosity for the monomer composi
6705790 Adhesive applicators with improved applicator tips March 16, 2004
An applicator for dispensing adhesive material includes a container body holding the adhesive material and an applicator tip configured to permit improved control and economy in application of the adhesive.
6676322 Impregnated applicator tip January 13, 2004
An applicator tip for dispensing a polymerizable and/or cross-linkable material which is porous, absorbent or adsorbent and includes a polymerization or cross-linking initiator. The initiator initiates polymerization or cross-linking when the polymerizable and/or cross-linkable mater
6637967 Adhesive applicator tips with improved flow properties October 28, 2003
An article of manufacture for dispensing an adhesive material, such as a synthetic or semi-synthetic polymerizable or cross-linkable monomer material, includes a container body, and a porous applicator tip having a proximal end that is attached to the container body, and a distal end
6620846 Absorbable adhesive compositions September 16, 2003
A method of treating living tissue includes applying to living tissue a biocompatible adhesive composition containing at least one alkyl ester cyanoacrylate monomer and a polymerization initiator or accelerator, wherein the polymerization initiator or accelerator is a quaternary amine.
6616019 Adhesive applicator with improved applicator tip September 9, 2003
An applicator for dispensing adhesive material, includes a container body, and an applicator tip, where the adhesive material is located in the container body in a non-contacting relationship with the applicator tip prior to dispensing said adhesive material. The applicator tip has a
6607631 Adhesive compositions with reduced coefficient of friction August 19, 2003
A polymerizable monomer adhesive composition includes a 1,1-disubstituted ethylene monomer and at least one slip additive, where the slip additive causes a polymer film formed from the monomer to have a lower coefficient of friction than in an absence of the slip additive. The slip addit
6605667 Antioxidant enriched adhesive compositions and storage containers therefor August 12, 2003
An adhesive composition includes a polymerizable adhesive monomer and at least one antioxidant stabilizer, and/or a container for storing said monomer composition that includes an antioxidant stabilizer. The antioxidant stabilizer provides superior stabilization and shelf-life of the
6602496 Adhesive treatment for tinea corporis August 5, 2003
A method of treating or preventing tinea corporis, commonly known as ringworm of the skin, includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with or susceptible to tinea corporis, optionally with at least one of an additional anti-fungal agent
6595940 Applicator for dispensable liquids July 22, 2003
A disposable applicator includes a generally tubular applicator body having a closed proximal end and an open distal end and a frangible vial inside. The proximal end is covered by a drying swab while the distal end is covered by an applicator swab that is in open communication with the
6592281 Adhesive applicator tips with improved flow properties July 15, 2003
An article of manufacture for dispensing an adhesive material, such as a synthetic or semi-synthetic polymerizable or cross-linkable monomer material, includes a container body, and a porous applicator tip having a proximal end that is attached to the container body, and a distal end
6585967 Adhesive treatment for tinea cruris July 1, 2003
A method of treating or preventing tinea cruris, commonly known as Jock Itch, includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with or susceptible to tinea cruris, optionally with at least one of an additional anti-fungal agent or a skin care
6579469 Cyanoacrylate solutions containing preservatives June 17, 2003
An adhesive composition that contains a preservative is particularly useful as a medical adhesive and can include alkyl cyanoacrylate monomers. The preservative is preferably soluble in the monomer. The composition may optionally be sterilized by placing a mixture of a polymerizable adhe
6565840 Monomeric compositions effective as wound closure devices May 20, 2003
A biocompatible monomer composition includes: (A) at least one monomer, which forms a medically acceptable polymer; (B) at least one plasticizing agent present in the composition in an amount of from 0.5 wt. % to 15 wt. % of the composition; and (C) at least one acidic stabilizing agent
6547467 Microapplicators, delivery systems and methods for adhesives and sealants April 15, 2003
A microapplicator for dispensing and applying an adhesive or sealant material comprises a handle portion, an applicator tip connected to the handle portion, and a microreservoir at the applicator tip arranged to hold a small amount, about 20 microliters or less, of an adhesive/sealant
6512023 Stabilized monomer adhesive compositions January 28, 2003
An adhesive composition includes a polymerizable adhesive monomer, at least one vapor phase stabilizer, and at least one liquid phase stabilizer. The combination of at least one vapor phase stabilizer and at least one liquid phase stabilizer provides superior stabilization and shelf-life
6494896 Applicator for laparoscopic or endoscopic surgery December 17, 2002
A hand-held applicator delivers liquid or semi-liquid compositions, such as adhesives, to an internal tissue or organ in an even and controlled manner. The applicator includes a pump, a tubular extension that is thin enough to pass through an endoscopic pathway or trocar, a proximal end
6488944 1, 1-disubstituted ethylene adhesive compositions containing polydimethylsiloxane December 3, 2002
An adhesive composition that contains cyanoacrylate monomers and cyclic or alkyl- or phenyl-terminated linear polydimethylsiloxane is particularly useful in applications requiring flexibility and elasticity. A method of removing, reducing or preventing scar tissue including applying an
6478191 Applicator with protective barrier November 12, 2002
An applicator for dispensing compositions includes a crushable ampoule covered with a barrier material that serves as a protective barrier. The applicator can also include a body made of a flexible material that holds at least one crushable ampoule. The protective barrier protects the us
6455064 Method of applying an adhesive composition over a bioactive polymerization initiator or accelera September 24, 2002
A composition comprising a polymerizable adhesive monomer is applied over a biologically active initiator or accelerator for polymerization of the monomer. The biologically active initiator or accelerator is a medicament that provides a desired medical or therapeutic activity as well as
6439789 Polymerizable 1, 1-disubstituted ethylene monomer formulation applicators, applicator tips, appl August 27, 2002
A polymerizable 1,1-disubstituted ethylene formulation applicator includes polymerizable 1,1-disubstituted ethylene monomer. According to one embodiment, the monomer is surrounded by a container that may be engaged with an applicator tip The applicator tip has an internal cavity defined
6433096 Sterilized cyanoacrylate solutions containing thickeners August 13, 2002
A method of making a sterile adhesive composition includes placing a mixture of a polymerizable adhesive monomer and a thickening agent in a container, sealing the container, and sterilizing the mixture and the container. The method provides superior viscosity for the monomer composi
6428234 Adhesive applicator tips with improved flow properties August 6, 2002
An article of manufacture for dispensing an adhesive material, such as a synthetic or semi-synthetic polymerizable or cross-linkable monomer material, includes a container body, and a porous applicator tip having a proximal end that is attached to the container body, and a distal end
6428233 Adhesive applicator tips with improved flow properties August 6, 2002
An article of manufacture for dispensing an adhesive material, such as a synthetic or semi-synthetic polymerizable or cross-linkable monomer material, includes a container body, and a porous applicator tip having a proximal end that is attached to the container body, and a distal end
6425704 Adhesive applicators with improved applicator tips July 30, 2002
An applicator for dispensing adhesive material includes a container body holding the adhesive material and an applicator tip configured to permit improved control and economy in application of the adhesive.
6420590 Continuous processes and apparatus for forming cyanoacetate and cyanoacrylate July 16, 2002
Continuous processes for forming cyanoacrylate from polycyanoacrylate include stripping a solvent from a reaction mass; cracking a polymer in the reaction mass to form a cracked cyanoacrylate monomer and residue substances; and distilling the cracked cyanoacrylate monomer to produce a
6412639 Medical procedure kit having medical adhesive July 2, 2002
A medical procedure kit incorporates one or more surgical tools necessary to perform at least part of a medical procedure, along with a container having a quantity of a medical adhesive. Medical adhesives are useful as an alternate or an adjunct to surgical sutures and/or staples in woun
6376019 Impregnated applicator tip April 23, 2002
An applicator tip for dispensing a polymerizable and/or cross-linkable material which is porous, absorbent or adsorbent and includes a polymerization or cross-linking initiator. The initiator initiates polymerization or cross-linking when the polymerizable and/or cross-linkable mater
6372313 Package assembly with applicator and container for adhesive materials April 16, 2002
A package assembly or kit can be used in conjunction with storing and dispensing adhesive materials. The package assembly includes an enclosure in which an applicator and a container may be positioned. The container contains adhesive material. The enclosure may include a base and a cover
6352704 Flavored cyanoacrylate compositions March 5, 2002
A sterile or non-sterile flavored monomeric adhesive composition includes a flavoring additive and a monomer. The composition can be applied, for example, to skin or the inside of the mouth. A method of making a sterile, flavored adhesive composition includes placing a mixture of a p
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