| Patent Number |
Title Of Patent |
Date Issued |
| 7005527 |
Process for the production of beraprost and its salts |
February 28, 2006 |
| The present invention relates to a new process for the preparation of beraprost of formula (I) using new intermediates. ##STR00001## |
| 6482959 |
Process for the stereoselective reduction of .alpha.,.beta.-unsaturated ketones |
November 19, 2002 |
| A process for the preparation of .alpha.,.beta.-unsaturated alcohols of general formula (I), ##STR1##wherein R means an alkyl group of 1-4 carbon atoms, or benzoyloxy group optionally substituted with a phenyl group; R.sup.1 means a hydrogen atom or an alkyl group of 1-4 carbon ato |
| 6432928 |
Complexes and their compositions |
August 13, 2002 |
| This invention provides inclusion complexes of Taxol ((2aR-(a.alpha.,4.beta.,4.alpha..beta.,6.beta.,9.alpha.(.alpha.R*,.beta.S* ),11.alpha.,12.alpha.,12a.alpha.,12b.alpha.))-.beta.-(benzoylamino)-.alpha. -hydroxy-benzene-propanoic acid 6,12-b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5, |
| 5589513 |
Pharmaceutical composition and process for the preparation thereof |
December 31, 1996 |
| The invention relates to two phase pharmaceutical compositions comprising as active ingredient a MAO inhibitor and an uptake inhibitor together with usual pharmaceutical auxiliaries. The compositions can be used for the treatment of neurodegenerative diseases. As active ingredient option |
| 5571186 |
Pharmaceutical bone growth-promoting composition and process |
November 5, 1996 |
| The invention relates to a combination useful for the substitution of bone defects having pathologically developed or being artificially established as well as compositions containing these combinations. The combinations of the invention preferably contain in a weight ratio of 1:9 to 9:1 |
| 5516778 |
Method for improving tissue antioxidant status |
May 14, 1996 |
| The invention relates to a method of using 3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione (generic name:pentoxifylline) and/or 1-(3',4'-diethoxybenzyl)-6,7-diethoxy-3,4 -dihydroisoquinolinium theophylline-7-acetate (Depogen) or monohydrate thereof to improve mammalian ti |
| 5475000 |
3-(substituted tetrazolyl)-4-oxo-4H-pyrido-[1,2-a]pyrimidines, salts thereof, pharmaceutical com |
December 12, 1995 |
| 4-oxo-4H-pyrido[1,2-a]-pyrimidines are disclosed of the formula ##STR1## wherein R is a C.sub.1-6 alkyl, C.sub.3-6 alkenyl, C.sub.3-6 alkynyl, C.sub.3-7 cycloalkyl, --(CH.sub.2).sub.n --COOR.sup.3 wherein R.sup.3 is C.sub.1 to C.sub.4 alkyl and n is 0 or 1 or a C.sub.7-8 aralkyl grou |
| 5455237 |
Acaricidally active tetrazine derivatives |
October 3, 1995 |
| The invention relates to novel tetrazine derivatives of the formula (I), ##STR1## wherein X is fluorine, chlorine or bromine; andY is hydrogen or fluorine, as well as to a process for the preparation thereof.Furthermore, the invention relates to compositions containing the above comp |
| 5449828 |
Process for the preparation of propargyl ammonium-chloride |
September 12, 1995 |
| The present invention relates to a process for the preparation of L-isomer of propargyl-ammonium-chloride derivatives of the formula (I) ##STR1## by decomposing D-tartarte of L-isomer of the amine of the general ##STR2## wherein y is hydrogen or fluoro and by reacting the obtaine |
| 5441940 |
Process for the preparation of water soluble primycin and its components and pharmaceutical comp |
August 15, 1995 |
| The invention relates to a process for the preparation of water soluble primycin and to the separation of its components of formulae (A.sub.1) and (A.sub.3) either as single components or as a mixture of the two components. According to the invention(i) water insoluble primycin is reacte |
| 5424327 |
Combined compositions |
June 13, 1995 |
| The invention relates to novel combined compositions for combatting plant, animal and sanitarian as well as forestry, horticultural and warehouse pests. These compositions contain a pyrethroid-type insecticide as an insecticidally active ingredient and at least one fungicide inhibiting t |
| 5387588 |
Pyridopyrimidine derivatives, pharmaceutical compositions containing them and process for prepar |
February 7, 1995 |
| The present invention relates to novel 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide derivatives of the general formula (I) and the acid addition salts thereof, pharmaceutical compositions containing them and a process for their preparation. In the general formula (I) ##STR1## |
| 5380845 |
Process for the preparation of quinoline carboxylic acid derivatives |
January 10, 1995 |
| The invention relates to a new process for the preparation of antibacterial compounds of the Formula I ##STR1## wherein R.sup.1 stands for phenyl substituted by 1 or 2 halogen atoms;R.sup.2 stands for piperazinyl or 4-methyl-piperazinyl;and pharmaceutically acceptable salts thereof which |
| 5380761 |
Transdermal compositions |
January 10, 1995 |
| An anhydrous transdermal composition is disclosed comprising in a 20 to 100% lyotropic liquid crystalline arrangement:5 to 15 weight % of optically active or racemic N-methyl-N-(1-phenyl-2-propyl)-2-propynylamine or N-methyl-N-{1-(4-fluorophenyl)-2-propyl}-2-propynylamine or a pharma |
| 5338868 |
Process for preparing alpha-amino-phenylacetic acid-trifluoromethane sulfonic acid mixed anhydri |
August 16, 1994 |
| A process is disclosed for the preparation of a compound of the Formula (VI) ##STR1## wherein X is a hydrogen atom, or OH,Y is a hydrogen atom, OH or a methyl group,R.sup.2 is a CH--COOR group, or a group of the formula (XI) ##STR2## and R is a C.sub.1 to C.sub.2 alkyl group, wh |
| 5298496 |
Inclusion complexes of 3-morpholino-sydnonimine or its salts or its tautomer isomer, process for |
March 29, 1994 |
| The invention relates to inclusion complexes of 3-morpholino-sydnonimine or its salts or its tautomer isomer, process for the preparation thereof and pharmaceutical compositions containing the same.The inclusion complex of 3-morpholino-sydnonimine or its salt formed with cyclodextrin der |
| 5294712 |
Process for the preparation of quinoline carboxylic acids |
March 15, 1994 |
| The invention relates to a new process for the preparation of compounds of the Formula I ##STR1## (wherein R stands for hydrogen or methyl) and pharmaceutically acceptable salts thereof which comprises reacting a compound of the Formula V ##STR2## (wherein R.sup.1 and R.sup.2 |
| 5284950 |
Process for the preparation of quinoline carboxyolic acids |
February 8, 1994 |
| A method of using a compound of the Formula (V) ##STR1## or a pharmaceutically acceptable salt thereof is disclosed, wherein R.sup.1 and R.sup.2 are each C.sub.1 to C.sub.6 aliphatic acyloxy, unsubstituted or substituted by halogen, or are each C.sub.7 to C.sub.11 aromatic acylox |
| 5273953 |
Pesticidal compositions comprising ethoxylated citric or tartaric acid derivatives as stabilizin |
December 28, 1993 |
| The invention relates to a plant protecting or veterinary or additive composition, containing beside the active ingredient and other usually applied auxiliaries, such as solid and liquid carrier(s), surface active agent(s) and further additive(s), one or more surface active agent(s) of |
| 5260426 |
Process for the preparation of pseudo primycin |
November 9, 1993 |
| The invention relates to antibacterial pseudo-primycin complexes of formula (I) ##STR1## to the components and acid addition salts thereof, as well as to the preparation of these compounds and to the pharmaceutical compositions containing said compounds as active ingredient.In th |
| 5252572 |
Pyridopyrimidine derivatives, pharmaceutical compositions containing them and process for prepar |
October 12, 1993 |
| The present invention relates to novel 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide derivatives of the general formula (I) and the acid addition salts thereof, pharmaceutical compositions containing them and a process for their preparation. In the general formula (I) ##STR1## |
| 5247102 |
Process for the preparation of substituted isoflavone derivative |
September 21, 1993 |
| The invention relates to a process for the preparation of pure isoflavone derivatives of the general formula (I), ##STR1## wherein R stands for hydrogen or isopropyl,R.sup.2 and R.sup.3 stand for hydrogen or C.sub.1-2 alkoxy by reacting a rezorcinol-derivative of the general formula |
| 5235109 |
Process for the preparation of ketone compounds |
August 10, 1993 |
| The invention relates to an improved, large scale process for the preparation of compounds of formula (I) ##STR1## wherein R is halogen atom or hydroxyl,R.sup.2 is hydrogen atom or hydroxyl,R.sup.3 and R.sup.4 are hydrogen or alkoxy having 1-6 carbon atoms. |
| 5220068 |
Psychostimulant agent |
June 15, 1993 |
| The present invention relates to a pharmaceutical composition comprising as active ingredient a compound of the Formula I ##STR1## wherein R.sup.1 stands for straight or branched chain alkyl comprising 1 to 8 carbon atoms; phenyl alkyl having 7 to 10 carbon atoms; phenyl; or cycl |
| 5218117 |
Process for preparing isoquinoline compounds |
June 8, 1993 |
| The invention relates to novel compounds of the general formula (I), ##STR1## The compounds of the invention antagonize the effects of constrictive mediators, e.g. histamine, acetylcholine or serotonin; they show an antiallergic action and possess an antiinflammatory effect. Thus, th |
| 5217707 |
Pharmaceutical composition and process for the preparation thereof |
June 8, 1993 |
| The invention relates to a stabile, aqueous suspoemulsion containing as active ingredient 0.2-5 weight % of primycin, 5-25 weight % of propylene glycol, 0.5-5 weight % of non-ionic surface active agent, if desired 15 weight % of auxiliary agent and distilled water in an amount necessary |
| 5189062 |
Plant protecting agent |
February 23, 1993 |
| ULV plant protecting arthropodicidal formulation comprising alkyl aryl polyglycol ether as further additives in addition to the active ingredient(s) dissolved in the mixture of alphatic hydrocarbons and sunflower oil. The formulation according to the invention has an initial contact |
| 5182277 |
Fungicides and plant-growth controlling agents |
January 26, 1993 |
| A synergistic plant fungicide is disclosed which comprises:(A) a morpholine compound selected from the group consisting of:(a) N-tridecyl-2,6-dimethylmorpholine;(b) N-cyclododecyl-2,6-dimethylmorpholine;(c) N-alkyl(C.sub.12)-2,6-dimethylmorpholine; and(d) 4-(3-p-tert.-butylphenyl)-2-methylpropyl-6-c |
| 5179089 |
Isoquinoline compounds, compositions and use |
January 12, 1993 |
| The invention relates to novel compounds of the general formula (I), ##STR1## wherein R means hydrogen or a straight or branched chain C.sub.1-6 alkoxy group;R.sup.1 stands for hydrogen or a straight or branched chain C.sub.1-6 alkyl group;R.sup.2 represents hydrogen or a straight or |
| 5153349 |
Process for the preparation of cypermethrine isomers |
October 6, 1992 |
| The invention relates to a process for the preparation of such isomer mixtures of cypermethrine of the Formula (I) ##STR1## wherein carbon atoms indicated by 1, 3 and .alpha. stand for a chiral carbon atom and the wavy line indicates cis or trans configuration related to the cycl |
| 5151419 |
Composition for the treatment of schizophrenia |
September 29, 1992 |
| The present invention is related to a pharmaceutical composition suitable for the treatment of schizophrenia comprising an acid addition salt of (1)-N-(1-phenyl-isopropyl)-N-methyl-1-propynyl-amine in a therapeutically effective amount and optionally one or more neuroleptica and phar |
| 5110976 |
Insecticidal composition comprising more than one active ingredient |
May 5, 1992 |
| A process is disclosed for preparing a synergistic, crystalline product consisting of solely enantiomer pair 1RCisS and 1SCisR and enantiomer pair 1RTransS and 1STransR of cypermethrin in a 3:7 to 5:5 crystalline mixture, which comprises the steps of: (a) epimerizing an oily melt or a sa |
| 5104857 |
Pseudo-primycin complexes, components and acid addition salts thereof |
April 14, 1992 |
| The invention relates to antibacterial pseudo-primycin complexes of formula (I) ##STR1## to the components and acid addition salts thereof, as well as to the preparation of these compounds and to the pharmaceutical compositions containing said compounds as active ingredient.In th |
| 5096612 |
Multiphase systems |
March 17, 1992 |
| A graft lyotropic liquid crystalline composition having a viscosity less than 10 Pa.s comprising a low amount of surfactant(s), optionally co-surfactant(s), and/or solvents, optionally a polymer in relative stretched state and which is partly or totally penetrable by the medium and a |
| 5093359 |
Primycin components and process for the separation of the antibiotic complex |
March 3, 1992 |
| The invention relates to the components of primycin antibiotic complex and the salts thereof and to the process for the separation of the individual components by chromatography. A further object of the invention is a synergistic antimicrobial composition containing the said components a |
| 5091530 |
Baron chelates of quinoline carboxylic acids |
February 25, 1992 |
| The invention relates to a new process for the preparation of compounds of the general Formula I ##STR1## /wherein R stands for piperazinyl, 4-methyl-piperazinyl or 4-ethyl-piperazinyl group/ and pharmaceutically acceptable salts thereof which comprises reacting a compound of the |
| 5091411 |
Pseudo-primycin complexes, components and acid addition salts thereof as well as a process for t |
February 25, 1992 |
| The invention relates to antibacterial pseudo-primycin complexes of formula (I) ##STR1## to the components and acid addition salts thereof, as well as to the preparation of these compounds and to the pharmaceutical compositions containing said compounds as active ingredient.In th |
| 5064815 |
Primycin-containing colloidal basic gel |
November 12, 1991 |
| This invention relates to a primycin-containing colloidal basic gel comprising 5-30% of primycin and 95-70% of N-methyl-pyrrolidone-2. The invention also relates to antibacterial compositions particularly for the treatment of acne vulgaris comprising as active ingredient 0.1-100% of a |
| 5045311 |
Plant-protective composition of increased stability containing nonionic surfactant only |
September 3, 1991 |
| The invention relates to an emulsifiable microemulsion concentrate containing a phophoric acid ester and/or thiophosphoric acid ester as active ingredient. In addition to 20 to 80% by weight of active ingredient, the composition comprises: 7 to 70% by weight of a nonionic surface act |
| 5043338 |
Fungicide compositions |
August 27, 1991 |
| The invention relates to synergistic combinations of known fungicide active ingredients and their application in plant protection. |
| 5043326 |
Inclusion complex of 7-isopropoxy-isoflavon formed with cyclodextrin, the preparation thereof an |
August 27, 1991 |
| The invention relates to the inclusion complexes of 7-isopropoxy-isoflavon formed with cyclodextrin or cyclodextrin derivatives as well as to the pharmaceutical compositions containing these inclusion complexes as active ingredient. The invention further relates to the preparation of the |
| 5043163 |
Pesticide composition |
August 27, 1991 |
| The present invention relates to a multi-component pesticidal composition against anthropoda containing as active ingredient pyrethroides and phosphate esters and optionally piperonyl butoxide and excipients comprising as pyrethroid component 0.1 to 40 percent by weight of cypermethr |
| 5023337 |
Chemical process for the preparation of pharmaceutically active compounds |
June 11, 1991 |
| The present invention is directed to the preparation of benzimidazole derivatives of the formula (I), ##STR1## wherein A=stands for S, SO or SO.sub.2,R.sup.1 =stands for C.sub.1-4 alkyl group,R.sup.2 =stands for C.sub.1-4 alkyl, C.sub.3-7 cycloalkyl or C.sub.6-10 aryl or aralkyl,comp |
| 5023242 |
Primycin salts |
June 11, 1991 |
| The invention relates to salts of primycin formed with an organic acid--preferably a C.sub.1-16 aliphatic carboxylic acid, a halogenated carboxylic acid, an aliphatic dicarboxylic acid, an aromatic carboxylic acid, a substituted aromatic carboxylic acid or an organic sulfonic acid--o |
| 5013754 |
Insecticidal composition comprising more than one active ingredient |
May 7, 1991 |
| According to the present invention there is provided a synergistic insecticidal composition containing more than one active ingredients and being harmless to environment characterized by comprising in an amount of from 0.001 to 99% by weight a synthetic pyrethroid of the Formula /I/ |
| 5008386 |
Methylated cyclodextrin type compounds and process for preparing same |
April 16, 1991 |
| The invention relates to novel partially methylated carboxyacyl-cyclodextrins of the general formula (I), ##STR1## wherein A means the cyclodextrin skeleton of the general formula (II) ##STR2## containing the substituents in the position labelled by the wavy line; W stands f |
| 5008292 |
Pesticidal method |
April 16, 1991 |
| The invention relates to N-[2-(4-fluorophenyl)-1-methyl]-ethyl-N-methyl-N-propynyl amine of the Formula I ##STR1## and isomers and salts thereof. The compound of the Formula I is useful as an insecticide. |
| 5006545 |
Veterinary compositions against endoparasites containing cypermethrin and albendazole |
April 9, 1991 |
| A veterinary composition is disclosed which is suitable against endoparasites and which contains as active ingredients:(a) alpha-(cyano)-3-(2,2-dichlorovinyl)-2,2-dimethyl-cyclopropane-carboxylic a cid-3-phenoxybenzyl ester or any isomeric mixture thereof; and(b) 5(6)-propylthio-2-benzimi |
| 4999454 |
Process for the preparation of trichloromethyl carbinols |
March 12, 1991 |
| The invention is directed to a new process for the preparation of carbinols of the general formula I ##STR1## by reaction chloral and olefins of the general formula ##STR2## and by optional acylation of the product comprising dissolving a catalyst of the general formula IIIin |
| 4988693 |
Fungicide compositions |
January 29, 1991 |
| The invention relates to synergistic combinations of known fungicide active ingredients and their application in plant protection. |
