| Patent Number |
Title Of Patent |
Date Issued |
| RE39219 |
Growth arrest homebox gene |
August 1, 2006 |
| A novel growth arrest homeobox gene has been discovered and the nucleotide sequences have been determined in both the rat and the human. The expression of the novel homeobox gene inhibits vascular smooth muscle cell growth. The growth arrest homeobox gene hereinafter referred to as t |
| RE37933 |
Viral vectors and their use for treating hyperproliferative disorders, in particular restenosis |
December 10, 2002 |
| The present invention relates to replication defective recombinant viruses which contain at least one inserted gene encoding all or part of the protein GAX or of a variant of this protein, and to their therapeutic use, in particular for treating post-angioplastic restenosis. |
| 7623925 |
Methods for selectively stimulating components in, on, or near the pudendal nerve or its branche |
November 24, 2009 |
| Systems and methods selectively stimulate components of the pudendal nerve away from the sacral root to evoke desired physiologic responses in persons who lack the ability to otherwise produce these responses--e.g., maintain continence and/or produce micturition, and/or provide male/ |
| 7620440 |
Direct temporal encoding of spatial information |
November 17, 2009 |
| An improved imaging technique and apparatus for direct temporal encoding of spatial information of an object is presented. The signal collected from the object after application of excitation energy in a magnetic field is directly representative of the spatial position of the object |
| 7616735 |
Tomosurgery |
November 10, 2009 |
| Systems, methods, and other embodiments associated with Tomosurgery are described. One method embodiment includes logically dividing a target volume into treatment slices to be radiated individually by co-planar beams. The method embodiment also includes planning a two dimensional pa |
| 7606612 |
System and method to perform parallel imaging |
October 20, 2009 |
| A system and method to perform parallel MR imaging are disclosed. The system comprises an MR imaging machine and a probe having at least two MR RF reception coils. Each coil of the probe is operationally connected to a separate receiver channel of the MR imaging machine. The MR imaging |
| 7596402 |
MRI probe designs for minimally invasive intravascular tracking and imaging applications |
September 29, 2009 |
| A probe suitable for attachment to, or incorporation in, a medical interventional device, such as a catheter, and which may be employed for tracking, imaging, or both, includes a first material having an MR resonance frequency distinct from a resonance frequency of a second material |
| 7571000 |
Apparatus for stimulating components in, on, or near the pudendal nerve or its branches to achie |
August 4, 2009 |
| Apparatus for control of physiological functions, including physiological functions of the urinary tract, using at least one electrode sized and configured to be located on, in, or near a targeted component of the pudendal nerve, and/or its branch(es), and/or its spinal root(s). The |
| 7562581 |
Wireless sensor platform for harsh environments |
July 21, 2009 |
| Reliable and efficient sensing becomes increasingly difficult in harsher environments. A sensing module for high-temperature conditions utilizes a digital, rather than analog, implementation on a wireless platform to achieve good quality data transmission. The module comprises a sensor, |
| 7560257 |
Diagnostic methods for age related macular degeneration |
July 14, 2009 |
| Diagnostic methods for identifying a test subject who has or is at risk of developing age-related macular degeneration (AMD) or an analogous disease associated with oxidation of DHA-containing lipids are provided. In one aspect, the methods comprise: assaying for the presence of elevated |
| 7558414 |
Iterative image reconstruction |
July 7, 2009 |
| Systems and methods using an image produced by a constrained image reconstruction process as a constraint in a forward iterative reconstruction process are described. One example system may include a constrained reconstruction logic to receive an initial data having an initial format |
| 7554004 |
Allelic series of genomic modifications in cells |
June 30, 2009 |
| The present invention relates to methods of producing an allelic series of modifications in genes of interest in a cell. In particular, the invention provides methods for using nucleic acid sequence-modifying agents (e.g., chemicals, electromagnetic radiation, etc.) to introduce modi |
| 7545966 |
Efficient methods for reconstruction and deblurring of magnetic resonance images |
June 9, 2009 |
| Methods are described for efficient reconstruction of MRI data. In one practice, new reconstruction algorithms for non-uniformly sampled k-space data are presented. In the disclosed algorithms, Iterative Next-Neighbor re-Gridding (INNG) and Block INNG (BINNG), iterative procedures are |
| 7521020 |
Device for precise chemical delivery and solution preparation |
April 21, 2009 |
| A burette (10, 110, 200) suitable for delivery of a reagent into a target solution (50) employs diffusion for delivering the reagent. The reagent is in the form of a solution, which is combined with a matrix material (22), such as a gel or porous ceramic. A membrane (32) covers a deliver |
| 7510871 |
Alzheimer model for drug screening |
March 31, 2009 |
| The present invention relates to methods and reagents for drug screening. Screening methods are disclosed employing neuronal cells that have been treated so as to exhibit characteristics associated with a re-entry into the cell cycle. One treatment approach comprises transfection of neur |
| 7486839 |
Efficient method for MR image reconstruction using coil sensitivity encoding |
February 3, 2009 |
| SENSitivity Encoding (SENSE) has demonstrated potential for significant scan time reduction using multiple receiver channels. SENSE reconstruction algorithms for non-uniformly sampled data proposed to date require relatively high computational demands. A Projection Onto Convex Sets ( |
| 7486498 |
Strong substrate alloy and compressively stressed dielectric film for capacitor with high energy |
February 3, 2009 |
| A capacitor anode (1) includes a substrate (10) which is formed from an alloy, metal, or metal compound which has a high tensile yield strength and high elastic modulus. The material has a composition which can be anodized, yielding an adherent and compressively stressed dielectric film |
| 7485420 |
Methods and compositions for detecting colon cancers |
February 3, 2009 |
| This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as colon neoplasia. |
| 7471973 |
Determining a surface geometry of an object |
December 30, 2008 |
| Methods for determining a surface geometry of an object, including determining a first projection matrix based on a first imaging device, determining a second projection matrix based on a second imaging device, obtaining at least one first two-dimensional (2D) image of the object usi |
| 7470538 |
Cell-based therapies for ischemia |
December 30, 2008 |
| The invention provides, among other things, methods for treating an ischemic tissue in a subject in need thereof. The invention further provides methods for increasing the blood flow to an ischemic tissue in a subject in need thereof, such as to ischemic myocardium. The invention fur |
| 7442375 |
Compositions of beta-defensin inducing agents |
October 28, 2008 |
| The disclosure provides, among other things, beta-defensin related agents for the treatment and prevention of viral infections, and particularly HIV infections. The disclosure provides methods for identifying additional beta-defensin related agents and for improving available beta-de |
| 7432050 |
Methods and compositions for detecting colon cancers |
October 7, 2008 |
| This application describes methods and compositions for detecting and treating HLTF-associated neoplasia. Differential methylation of the HLTF nucleotide sequences has been observed in HLTF-associated neoplasia such as colon neoplasia. |
| 7389145 |
Systems and methods for reversibly blocking nerve activity |
June 17, 2008 |
| Systems and methods for blocking nerve impulses use an implanted electrode located on or around a nerve. A specific waveform is used that causes the nerve membrane to become incapable of transmitting an action potential. The membrane is only affected underneath the electrode, and the eff |
| 7365181 |
Probes for chondrogenesis |
April 29, 2008 |
| Markers for detecting and staging chondrogenesis in cells are provided. In one aspect the markers are isolated polynucleotides, referred to hereinafter as CZF-1 and CZF-2, and fragments thereof. In one embodiment, the CZF-1 polynucleotide comprises the open reading frame sequence set |
| 7362444 |
Interferometers for optical coherence domain reflectometry |
April 22, 2008 |
| An interferometer system includes an optical radiation source, an optical circulator connected between the optical radiation source and a sample location for transmitting optical radiation from the optical radiation source to the sample location, an output of the optical circulator c |
| 7359745 |
Method to correct magnetic field/phase variations in proton resonance frequency shift thermometr |
April 15, 2008 |
| PRF shift MRI data is acquired. The PRF shift MRI data may include signals affected by both a desired PRF shift and an undesired PRF shift. Thus, example systems and methods describe manipulating the PRF shift MR! data to make it substantially free of the effects of the undesired PRF shi |
| 7341839 |
Diagnostic methods for age related macular degeneration |
March 11, 2008 |
| Diagnostic methods for identifying a test subject who has or is at risk of developing age-related macular degeneration (AMD) or an analogous disease associated with oxidation of DHA-containing lipids are provided. In one aspect, the methods comprise: assaying for the presence of elevated |
| 7326566 |
Compositions and methods for screening antimicrobials |
February 5, 2008 |
| A method for screening compounds for antimicrobial activity is described that utilizes bacterial protein-protein binding in vitro. The method may be performed using immobilized elements and the immobilization may be carried out using a variety of immobilization means (e.g., columns, |
| 7301342 |
Bunched phase encoding (BPE) |
November 27, 2007 |
| Systems, methodologies, media, and other embodiments associated with improving MRI scan times and mitigating the effects of aliasing artifacts when the Nyquist data sampling threshold is not satisfied are described. One exemplary method embodiment includes producing an oscillating phase |
| 7292828 |
Miniaturized multichannel transmitter and wireless telemetry system |
November 6, 2007 |
| A multichannel wireless telemetry system is disclosed. The system includes a transmitter and a receiver in communication with the transmitter. The transmitter includes a signal processing chip. The signal processing chip includes a plurality of input preamplifiers, a plurality of selecti |
| 7260436 |
Implantable networked neural system |
August 21, 2007 |
| A neural prosthesis includes a centralized device that can provide power, data, and clock signals to one or more individual neural prosthesis subsystems. Each subsystem may include a number of individually addressable, programmable modules that can be dynamically allocated or shared |
| 7255914 |
Variable refractive index polymer materials |
August 14, 2007 |
| A new class of composite polymer films where the refractive index can be varied by simple compressive or extensive forces. The films are comprised of alternating layers of an elastomer and a glassy polymer or two different elastomers. When the layer spacing is much less than the wave |
| 7233143 |
BRORC-S2PD |
June 19, 2007 |
| Systems, methodologies, media, and other embodiments associated with a block-by-block off-resonance frequency estimation method are described. One exemplary method embodiment includes calculating a field map from local B.sub.0 off resonance frequency estimates. The example method may |
| 7223988 |
Color tunable photoluminescent blends |
May 29, 2007 |
| Embodiments of the present invention are directed toward a photoluminescent article comprising at least one host material and at least one color tunable photoluminescent dye. In certain embodiments, the emission spectrum of the at least one tunable photoluminescent dye may be depende |
| 7172874 |
Diagnostic methods for age related macular degeneration |
February 6, 2007 |
| Diagnostic methods for identifying a test subject who has or is at risk of developing age-related macular degeneration (AMD) or an analogous disease associated with oxidation of DHA-containing lipids are provided. In one aspect, the methods comprise: assaying for the presence of elevated |
| 7118912 |
Methods and compositions for categorizing patients |
October 10, 2006 |
| The disclosure provides, among other things, molecular markers for categorizing the neoplastic state of a patient, methods for using the molecular markers in diagnostic tests, nucleic acid and amino acid sequences related to the molecular markers, reagents for detection of molecular |
| 7102756 |
Interferometers for optical coherence tomography and reflectometry |
September 5, 2006 |
| An interferometer system includes an optical radiation source, an optical circulator connected between the optical radiation source and a sample location for transmitting optical radiation from the optical radiation source to the sample location, an output of the optical circulator c |
| 7081516 |
Methods for categorizing patients |
July 25, 2006 |
| The disclosure provides, among other things, molecular markers for categorizing the neoplastic state of a patient, methods for using the molecular markers in diagnostic tests, nucleic acid and amino acid sequences related to the molecular markers, reagents for detection of molecular |
| 7078899 |
Pareto-optimal magnetic resonance data acquisition |
July 18, 2006 |
| A magnetic resonance data acquisition method includes designating a plurality of parameters that are representative of conditions for acquiring data from a magnetic resonance apparatus, at least one of the parameters being variable; designating at least one objective function measuri |
| 7075658 |
Method for optical coherence tomography imaging with molecular contrast |
July 11, 2006 |
| Spatial information, such as concentration and displacement, about a specific molecular contrast agent, may be determined by stimulating a sample containing the agent, thereby altering an optical property of the agent. A plurality of optical coherence tomography (OCT) images may be a |
| 7072047 |
Method and system for quantitative image correction for optical coherence tomography |
July 4, 2006 |
| A method of correcting optical coherence tomography (OCT) image data obtained from a layered media sample includes identifying at least one interface from the obtained OCT data and correcting the OCT data for distortion at the at least one interface. The OCT image data can be correct |
| 7061622 |
Aspects of basic OCT engine technologies for high speed optical coherence tomography and light s |
June 13, 2006 |
| An optical coherence tomography (OCT) system including an interferometer provides illuminating light along a first optical path to a sample and an optical delay line and collects light from the sample along a second optical path remitted at several scattering angles to a detector. In one |
| 7047078 |
Methods for stimulating components in, on, or near the pudendal nerve or its branches to achieve |
May 16, 2006 |
| Systems and methods control physiological functions of the urinary tract using at least one electrode sized and configured to be located on, in, or near a targeted component of the pudendal nerve. The systems and methods apply an electrical signal to the electrode at a selected frequ |
| 7042215 |
Three point dixon techniques in MRI spiral trajectories with off-resonance correction where each |
May 9, 2006 |
| Spiral imaging has recently gained acceptance for rapid MR data acquisition. One of the main disadvantages of spiral imaging, however, is blurring artifacts due to off-resonance effects. Dixon techniques have been developed as methods of water-fat signal decomposition in rectilinear |
| 7016719 |
System and methods for noninvasive electrocardiographic imaging (ECGI) using generalized minimum |
March 21, 2006 |
| Methods and systems for computing epicardial surface electric potentials based on measured body surface electric potentials, where the methods and systems include representing at least one geometric relationship between at least one body surface electric potential measuring system and th |
| 7006232 |
Phase-referenced doppler optical coherence tomography |
February 28, 2006 |
| A phase-referenced Doppler optical coherence tomography (OCT) system includes a low-coherence optical radiation source and a reference source co-propagated to a sample arm and a reference arm. The low-coherence and reference optical radiation reflected from the reference and arms is |
| 7002754 |
Multilayer polymer gradient index (GRIN) lenses |
February 21, 2006 |
| Disclosed are axial, radial or spherical gradient index (GRIN) lenses fabricated by layering composite polymer films into an hierarchical structure. |
| 7002342 |
System and method for reducing effects of rotational motion |
February 21, 2006 |
| A method and system for improving image quality by correcting errors introduced by rotational motion of an object being imaged is provided (1150). The method provides a computer executable methodology for detecting a rotation (1110) and selectively reordering (1160), deleting and/or |
| 6975900 |
Systems and methods for determining a surface geometry |
December 13, 2005 |
| Methods and systems for determining a surface geometry of an object, including determining a first projection matrix based on a first imaging device, determining a second projection matrix based on a second imaging device, obtaining at least one first two-dimensional (2D) image of the |
| 6942905 |
Buff-free liquid crystal alignment using poly(ionomer) coatings |
September 13, 2005 |
| The present invention consists of materials and a processing method for coating rigid-rod poly(ionomers) or salts thereof, in a solvent system, directionally on charged surfaces resulting in the formation of liquid crystal display surfaces with planar alignment and pretilt. |
