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Brown University Patents
Assignee:
Brown University
Address:
Providence, RI
No. of patents:
31
Patents:




Patent Number Title Of Patent Date Issued
7612038 Biglycan and related therapeutics and methods of use November 3, 2009
The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated prote
7569734 Method of using rhodium quinonoid catalysts August 4, 2009
In accordance with aspects of the invention methods of using rhodium hydroquinone catalysts for the conjugate addition of boronic acids are disclosed.
7551657 Magneto-optoelectronic switch and sensor June 23, 2009
A Magneto-Optoelectronic Device MOD (10) includes a magnetic sensing device (12), such as a magnetoresistive device or a magnetic tunnel junction device, that is combined with a semiconductor light emitter (14), such as a LED or a laser diode, to create a compact integrated device wh
7543791 Tunable inverse pendulum vibration isolation system June 9, 2009
A vibration isolation system couples two resonant systems to provide isolation of transverse vibrational motions. The first system incorporates a plurality of tunable inverse pendulum assemblies. The second system incorporates a table of large mass suspended at several points from th
7505154 Optical method for the characterization of laterally patterned samples in integrated circuits March 17, 2009
Disclosed is a method for characterizing a sample having a structure disposed on or within the sample, comprising the steps of applying a first pulse of light to a surface of the sample for creating a propagating strain pulse in the sample, applying a second pulse of light to the sur
7495097 Rhodium quinonoid catalysts February 24, 2009
In accordance with one aspect of the invention a rhodium quinonoid catalyst is disclosed.
7492934 Methods and apparatus for model-based detection of structure in view data February 17, 2009
In one aspect, a method and apparatus for determining a value for at least one parameter of a configuration of a model associated with structure of which view data has been obtained including detecting at least one feature in the view data, and determining the value for the at least one
7440479 Magneto-optoelectronic switch and sensor October 21, 2008
A Magneto-Optoelectronic Device MOD (10) includes a magnetic sensing device (12), such as a magnetoresistive device or a magnetic tunnel junction device, that is combined with a semiconductor light emitter (14), such as a LED or a laser diode, to create a compact integrated device wh
7387032 Methods and apparatus for measuring the viscoelastic response of vocal fold tissues and scaffold June 17, 2008
In one aspect the present invention concerns methods and apparatus for measuring the mechanical properties of soft materials across a frequency regime. In particular, the present invention concerns methods and apparatus using torsional waves to measure the mechanical properties of vo
7363177 Apparatus and method for performing the time delay estimation of signals propagating through an April 22, 2008
A system and method for increasing the accuracy of time delay estimates of signals propagating through an environment. The system includes one or more sensors for receiving a plurality of signals, and a time delay estimator for measuring time delays between multiple pairs of signals. At
7339676 Optical method and system for the characterization of laterally-patterned samples in integrated March 4, 2008
Disclosed is a method for characterizing a sample having a structure disposed on or within the sample, comprising the steps of applying a first pulse of light to a surface of the sample for creating a propagating strain pulse in the sample, applying a second pulse of light to the sur
7289388 Estimation of background noise and its effect on sonar range estimation October 30, 2007
A system and method for estimating the SNR in a sonar environment and for determining the effect of the estimated SNR on sonar ranging accuracy. The system includes a sensor, a transmitter, a receiver, a plurality of band-pass filters, a cross correlator, and a data analyzer. The tra
7257711 Efficient authenticated dictionaries with skip lists and commutative hashing August 14, 2007
An efficient and practical method for dynamically maintaining an authenticated dictionary uses a skip list data structure and communicative hash functions to provide a dictionary database (201) that stores information objects so that any individual object can be authenticated as belo
7239580 Noise adaptive sonar signal processor July 3, 2007
A system and method of performing sonar range estimations in a noisy sonar environment. The system includes a sensor, a transmitter, a receiver, a plurality of band-pass filters, a cross correlator, and a data analyzer. The transmitter transmits a pulse through a transmission medium. The
7220972 Method and apparatus for the characterization and analysis of the shape of molecules and molecul May 22, 2007
A method and apparatus to characterize a shape of an isomeric form of a sample comprised of a molecule or a cluster of molecules. The method includes raising an electron of the sample to a Rydberg state having an orbital diameter sufficient to encompass at least a portion of the samp
7198785 Systems and methods related to degradation of uremic toxins April 3, 2007
The present invention generally relates to the treatment of uremic toxins in vivo using uremic toxin-treating enzymes, and/or cells capable of producing uremic toxin-treating enzymes or otherwise reacting with uremic toxins. Non-limiting examples of cases where the treatment of uremic
7196758 Method of alignment of liquid crystals comprising exposing an alignment material to an interfere March 27, 2007
A method includes exposing an alignment material to an interference pattern to cause a chemical reaction in the alignment material and exposing the alignment material to a liquid crystal, where the liquid crystal aligns relative to the alignment material based on the interference pat
7006747 Optical devices incorporating photo reactive polymers February 28, 2006
A method for forming a display device including generating a face plate element by providing a first substrate with a photoactive resin thereon and exposing the photoactive resin to a light interference pattern formed by three collimated and coherent light sources, resulting in columnar
6963077 Sublithographic nanoscale memory architecture November 8, 2005
A memory array comprising nanoscale wires is disclosed. The nanoscale wires are addressed by means of controllable regions axially and/or radially distributed along the nanoscale wires. In a one-dimensional embodiment, memory locations are defined by crossing points between nanoscale wir
6958380 Polyurethane ionomers and methods for their preparation and formation October 25, 2005
The invention relates to improved polyurethane ionomers and methods for making the same. It was found that the polyurethane anionomers obtained by using the method of the invention had improved physical properties than those made by conventional methods. For example, the polyurethane ion
6949604 Polyurethane ionomer blends and methods for their preparation and formation September 27, 2005
The invention relates to blends of improved polyurethane ionomers with other polymers and methods for making the same. It was found that the blends of polyurethane anionomers obtained by using the method of the invention had improved physical properties than those made by conventional
6916821 Methods of treating disorders with Group I mGluR antagonists July 12, 2005
mGluR5 antagonists are used for the treatment and prevention of disorders, including Fragile X, autism, mental retardation, schizophrenia and Down's Syndrome. The methods of the invention can be used to treat epilepsy and anxiety in a human having Fragile X syndrome, autism, mental retar
6900479 Stochastic assembly of sublithographic nanoscale interfaces May 31, 2005
A method for controlling electric conduction on nanoscale wires is disclosed. The nanoscale wires are provided with controllable regions axially and/or radially distributed. Controlling those regions by means of microscale wires or additional nanoscale wires allows or prevents electric
6890931 Methods of treating disorders with group I mGluR antagonists May 10, 2005
Compositions and uses of mGluR5 antagonists for the treatment and prevention of neurological disorders, such as Fragile X, autism, mental retardation, schizophrenia and Down's Syndrome, are disclosed.
6710189 Method to produce novel polyketides March 23, 2004
A polyketide, or an antibiotic which is obtainable from the polyketide by a method comprising treating the polyketide with a culture medium conditioned by Saccharopolyspora erythraea, selected from the group consisting of: ##STR1## ##STR2##
6083523 Implantable biocompatable immunoisolatory vehicle for delivery of selected therapeutic products July 4, 2000
An immunoisolatory vehicle for the implantation into an individual of cells which produce a needed product or provide a needed metabolic function. The vehicle is comprised of a core region containing isolated cells and materials sufficient to maintain the cells, and a permselective,
6080555 Synthesis of polyketides from diketides June 27, 2000
Cell-free systems which effect the production of polyketides employing modular polyketide synthases are described. Libraries of new and/or known polyketides may also be produced in cell-free systems employing aromatic PKS, modular PKS or both.
5939323 Hyaluronan based biodegradable scaffolds for tissue repair August 17, 1999
A hyaluronic acid derivitized scaffold and method of forming are disclosed. The scaffolds are useful for various medical purposes such as tissue repair, tissue reconstruction and wound healing. In order to enhance these processes the scaffolds may be engineered to incorporate biologicall
5346908 Nitrogen-containing cyclohetero cycloheteroaminoaryl derivatives for CNS disorders September 13, 1994
Certain nitrogen-containing cyclohetero cycloalkylaminoaryl compounds are described for treatment of CNS disorders such as cerebral ischemia, psychoses and convulsions. Compounds of particular interest are of the formula: ##STR1## wherein each of R.sup.1, R.sup.4, R.sup.5, R.sup.
4911810 Modular sputtering apparatus March 27, 1990
A sputtering apparatus is constructed in modular form to facilitate changes in sputtering processes and target materials. At least two sputtering modules and a pumping stack module are arranged in series and in any desired order between a load module and an exit module. Each module is
4523319 Laser tape systems June 11, 1985
A laser tape system for use in the resonant cavity of laser consisting of a flexible tape carrying at least one lasing dye and adapted for insertion into the resonant cavity, and a drive mechanism for moving the tape such that different portions of the tape may be focused within the cavi

 
 
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